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What is the Chinese name of 2-bromo-4-iodotoluene?
2-Bromo-4-iodine toluene is one of the organic compounds. Its naming follows the chemical naming rules. "Toluene" means that there is a methyl-linked structure on the benzene ring as the base. "2-bromo" means that the second position of the benzene ring of toluene has a bromine atom phase; "4-iodine" means that there is an iodine atom attached to the fourth position of the benzene ring.
Chemical nomenclature is set for the structure and composition of the compounds. With toluene as the parent body, according to the numbering rules, the benzene ring carbon connected to the methyl ring is the first position, and the order is numbered. The structure of this compound is established, and it is called 2-bromo-4-iodotoluene according to the nomenclature, so that chemists can identify the same substance when communicating this substance without confusion. In the field of chemistry, the naming rules are rigorous and orderly, and all kinds of compounds are named according to this rule to facilitate academic discussions, experimental operations and industrial production.
What are the physical properties of 2-bromo-4-iodotoluene?
2-Bromo-4-iodotoluene is an organic compound. It has unique physical properties, let me tell you in detail.
Looking at its appearance, under room temperature and pressure, 2-bromo-4-iodotoluene is often colorless to light yellow liquid, pure in quality, and clear in appearance.
Smell its smell and emit the smell of unique organic compounds. Although it is not pungent and intolerable, it also has a characteristic smell, which is different from the smell of common hydrocarbon compounds and slightly smells of aromatic hydrocarbon halides.
In terms of its boiling point, its boiling point is relatively high due to the force between molecules. The presence of bromine and iodine atoms in the molecule enhances the intermolecular force, requiring a higher temperature to transform it from liquid to gaseous. According to relevant experimental measurements and theoretical calculations, the boiling point may be in a certain temperature range, which ensures that it is stable in a normal temperature environment.
As for the melting point, due to the influence of halogen atoms, the molecular arrangement is more regular, the interaction between molecules is enhanced, and the melting point is also increased accordingly. Under a specific low temperature environment, it will solidify from liquid to solid, showing a crystalline state with an orderly arrangement of structures.
In terms of solubility, 2-bromo-4-iodotoluene is a non-polar or weakly polar compound. According to the principle of similarity and miscibility, it has good solubility in organic solvents such as benzene, toluene, chloroform, etc., and can mutually dissolve with organic solvents to form a uniform solution. However, in water solvents with strong polarity, the solubility is extremely poor, and the two will be quickly layered after mixing, and the organic layer is in the upper or lower layer, depending on the density compared with water.
On the density, the density of bromine and iodine atoms is higher than that of common hydrocarbons due to their relatively large atomic masses. When mixed with less dense liquids such as water, 2-bromo-4-iodotoluene will settle at the bottom, forming clear layers.
In summary, the physical properties of 2-bromo-4-iodotoluene are determined by the halogen atoms in its molecular structure, and their applications in organic synthesis, chemical industry and other fields are closely related to these physical properties.
What are the chemical properties of 2-bromo-4-iodotoluene?
2-Bromo-4-iodotoluene is also an organic compound. It has the properties of halogenated aromatics, and the existence of halogen atoms bromine and iodine makes its chemical properties unique.
The first word about its nucleophilic substitution reaction. With its halogen atom activity, when encountering nucleophilic reagents, nucleophilic substitution can occur. If encountering hydroxyl negative ions, bromine or iodine atoms or replaced by hydroxyl groups, the corresponding alcohols will be produced. This reaction is easy to enter in alkaline media, and the capping base can increase the activity of nucleophilic reagents.
Times and elimination reactions. Under strong alkali and heating conditions, 2-bromo-4-iodotoluene can be eliminated. Bromine and hydrogen in the ortho-position of iodine, or co-elimination with halogen atoms, form an unsaturated bond, such as alkenes or alkynes, and then the product of elimination depends on the reaction conditions and substrate structure.
There is a coupling reaction. Under suitable catalysts and ligands, 2-bromo-4-iodotoluene can be coupled with other organohalides or organometallic reagents. For example, with Grignard reagents, catalyzed by metals, it can form carbon-carbon bonds and increase the carbon chain of molecules. It is an important method in organic synthesis to produce complex organic molecules.
Furthermore, the halogen atom of 2-bromo-4-iodotoluene can change the electron cloud density of the benzene ring, which affects the activity and localization of the electrophilic substitution reaction of the benzene ring. Its halogen atom is an ortho-para-localization group, which can induce electrophilic reagents to the ortho-para-position of the benzene ring, so that the electrophilic substitution reaction has a specific orientation, and can assist in the synthesis of aromatic hydrocarbon derivatives with specific structures. In short, 2-bromo-4-iodotoluene is rich in chemical properties and has a wide range
What are the main uses of 2-bromo-4-iodotoluene?
2-Bromo-4-iodotoluene, the Chinese name for 2-bromo-4-iodotoluene, is a chemical compound, and its main use is.
First, in the field of chemical synthesis, it is often used as a medium. The chemical synthesis is aimed at molecules, 2-bromo-4-iodotoluene because of its molecular activity of bromine and iodine, can many reaction. Such as Suzuki, in this case, it can be boron-containing chemical compounds under the catalytic action of reaction, forming a new carbon - carbon, this is important for building aryl compounds, and aryl compounds exist in materials, such as multi-domain. For another example, it can be reversed even negishi, and it can also form carbon-carbon molecules under catalytic induction, helping to synthesize various molecules.
Second, in the field of materials science, it is also important. Because of its specialization, it can be introduced into specific functionalities by chemical modification, and the special properties of the material can be improved. If it is introduced into the polymer, it is expected to improve the properties of the whole polymer. In the research of high-density materials, it may improve the properties of the material, such as the transfer rate of the fluidic, and provide new avenues for the development of electronic devices such as optical diodes (OLEDs) and energy pools.
Third, in terms of physicochemistry, it cannot be ignored. Molecules often need to introduce specific functions to improve the activity of the whole product, the ability of substitution, etc. 2-Bromo-4-iodotoluene can be used as a starting material or medium for the synthesis of specific molecules, and a multi-step reaction can be used to build a molecular skeleton with specific biological activities to develop new compounds.
What are 2-bromo-4-iodotoluene synthesis methods?
There are many ways to synthesize 2-bromo-4-iodotoluene. One way is to start with toluene. Toluene is brominated to obtain o-bromotoluene. This reaction requires a suitable catalyst, such as iron filings or iron tribromide, to interact with bromine and toluene at a suitable temperature and reaction conditions. The capped bromide atom is on the benzene ring of toluene, which is affected by the localization effect of methyl and is mostly replaced by ortho-sites.
After obtaining o-bromotoluene, the iodization reaction is carried out. At this time, an appropriate iodizing reagent needs to be selected, such as a mixed system of iodine elemental substance and potassium iodide, accompanied by an appropriate oxidizing agent, such as hydrogen peroxide or nitric acid. In a suitable solvent, such as glacial acetic acid, etc., after careful regulation of the reaction temperature and time, the hydrogen at the ortho-position of the bromine atom on the benzene ring of o-bromotoluene can be replaced by the iodine atom, and finally 2-bromo-4-iodotoluene can be obtained.
Another method can be used to iodize toluene first. In a specific reaction environment, the action of iodine and toluene is used to generate iodine-o-toluene. During the reaction, catalyst assistance may be required, and attention should also be paid to the control of the reaction conditions. After obtaining o-iodotoluene, the bromination reaction is carried out. This bromination step is similar to the above method of brominating toluene. Appropriate brominating reagents and catalysts are selected. Under suitable conditions, bromine atoms can be substituted for hydrogen at the interatomic position of iodine atoms on the o-iodotoluene benzene ring, and the purpose of synthesizing 2-bromo-4-iodotoluene can also be achieved.
Furthermore, other organic synthesis paths can be used. For example, using an appropriate aromatic halide as the starting material, the structure of the target molecule can be gradually constructed by means of coupling reaction. However, all these methods require careful consideration of the reaction conditions, the selection and dosage of reagents, and the separation and purification of intermediate products to obtain high-purity 2-bromo-4-iodotoluene.
