2-Bromo-4-Trifluoromethoxy-1-Iodobenzene

Fengxi Chemical

Specifications

HS Code	718619
Chemical Formula	C7H3BrF3IO
Molecular Weight	359.90
Appearance	Colorless to light yellow liquid
Boiling Point	N/A (experimental data may vary)
Melting Point	N/A (experimental data may vary)
Density	N/A (experimental data may vary)
Solubility	Soluble in common organic solvents like dichloromethane, chloroform
Flash Point	N/A (experimental data may vary)
Purity	Typically high - purity products around 95%+
Cas Number	N/A (exact number depends on source)
Odor	Characteristic organic odor
Stability	Stable under normal conditions but may react with strong oxidizing agents
Chemical Formula	C7H3BrF3IO
Molecular Weight	359.90
Appearance	Solid (Typical)
Solubility In Water	Insoluble (Aromatic halides' general property)
Solubility In Organic Solvents	Soluble (Aromatic halides' general property, e.g., in dichloromethane)
Vapor Pressure	Low (Aromatic halides' general property)
Stability	Stable under normal conditions (Aromatic halides' general property, but avoid strong oxidants)

As an accredited 2-Bromo-4-Trifluoromethoxy-1-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500g of 2 - bromo - 4 - trifluoromethoxy - 1 - iodobenzene packaged in a sealed glass bottle.
Storage	2 - bromo - 4 - trifluoromethoxy - 1 - iodobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition points. Keep it in a tightly sealed container to prevent exposure to air and moisture, which could potentially cause decomposition. Store separately from oxidizing agents and incompatible substances to avoid chemical reactions.
Shipping	2 - bromo - 4 - trifluoromethoxy - 1 - iodobenzene is shipped in sealed, corrosion - resistant containers. Adequate cushioning is used to prevent breakage. It follows strict hazardous chemical shipping regulations to ensure safe transit.

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2-Bromo-4-Trifluoromethoxy-1-Iodobenzene

General Information

Historical Development

Fu 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene This substance originated from the research of modern chemistry. At the beginning, chemists worked hard in the field of organic synthesis, hoping to obtain novel compounds to expand the boundaries of chemical cognition.
At that time, the method of organic synthesis was not as complete as it is today, but the wise men still tried again and again with tenacity. After many attempts, the way to synthesize this compound was obtained. The initial synthesis, the yield was very small, and the steps were complicated, requiring extremely high skills and precise operation.
With the passage of time, the chemical technology has become more and more exquisite, and the synthesis method has also been continuously improved. On the basis of future generations, optimize the process and improve the yield, so that this compound can gradually be prepared on a large scale. Its application in organic synthesis, drug research and development and other fields has also become increasingly apparent, contributing to the development of chemistry and promoting the continuous progress of this field.

Product Overview

Today there is a substance called 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene. This is an organic compound with a unique structure. Looking at the benzene ring, the bromine atom, the iodine atom and the trifluoromethoxy group are on one side.
Bromine, a halogen element, is also active and is often a key factor in chemical reactions. The iodine and halogen group has a large atomic radius and is easily deformed by electron clouds, which has a huge impact on the properties of compounds. The trifluoromethoxy group, due to the fluorine atom, has extremely strong electronegativity, giving this compound special chemical and physical properties.
This compound is widely used in the field of organic synthesis. It can be used as an intermediate to build more complex organic molecules through various chemical reactions. Its unique structure can guide the direction of the reaction and improve the yield of the target product. It has potential application value in pharmaceutical research and development, materials science and many other aspects, and is an important substance that cannot be ignored in chemical research.

Physical & Chemical Properties

2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene is an organic compound with unique physicochemical properties. It is a colorless to pale yellow liquid that is stable at room temperature and pressure.
From the perspective of physical properties, the boiling point and melting point of this substance depend on specific conditions and are related to intermolecular forces. Its density is also one of its characteristics, which affects its distribution in different media.
Discussing chemical properties, bromine, iodine and trifluoromethoxy functional groups in this compound are active. Bromine and iodine atoms can participate in nucleophilic substitution reactions, and trifluoromethoxy gives it special electronic effects and chemical stability. It is used in the field of organic synthesis or to construct complex molecular structures, and is a key raw material for many organic reactions.

Technical Specifications & Labeling

Husband 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene, the thing that is transformed is also. Its technology is not good (commodity is not good) until it needs to be changed. The shape, there is a specific shape, or a solid, or a liquid, its color is also determined. If it is good, the degree of accuracy needs to be determined until the relative quality, and the amount of quality must be controlled.
As long as it is good, it is clear that its name, 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene is not good. And its danger is also clear. If it encounters fire or water, it will cause harm to people. On the package, the grid is clearly discernible, so that the user can understand its nature and use it properly, so as to obtain the benefits of this thing and avoid its harm.

Preparation Method

The method of preparing 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene is related to the raw materials and production process, reaction steps, and catalytic mechanism.
First take the appropriate raw materials, such as compounds containing bromine, fluorine and iodine, and the proportions need to be precisely prepared. In the reactor, control the appropriate temperature and pressure, and add the raw materials in sequence. In the first step, the bromine-containing and fluorine-containing compounds are reacted first, and after a specific time, they are fully integrated to form a preliminary product.
Next, add the iodine-containing reactants. In this step, the reaction conditions need to be carefully controlled, or the temperature is adjusted, or the pH is controlled. With the help of a specific catalyst, the reaction process needs to be accelerated and the purity of the product is improved. The choice of catalyst is crucial, and it is related to the reaction rate and product quality.
After the reaction is completed, it is separated and purified to remove its impurities to obtain pure 2-Bromo-4-Trifluoromethoxy-1-Iodobenzene. Each step requires rigorous operation and follow the procedures to ensure the quality and quantity of the product.

Chemical Reactions & Modifications

The current technique of transformation is related to 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene. Its transformation and change are really the focus of our researchers.
The principle of transformation and reaction is that the reactants react according to their properties and form new qualities. In 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene, its structure is unique and the atoms are arranged in an orderly manner, which is the basis of response. When it encounters other agents, electrons migrate and bonds are broken, and new substances are born.
The natural transformation should not be static. If you want to do something good, you must seek change. The way to change, or adjust the temperature, the temperature should be high speed, molecular dynamic drama, collision frequency; or change the pressure, the pressure should be appropriate. It can also be an easy catalyst, and a good agent can reduce the energy barrier of the application and promote the smooth flow of the application.
My generation of researchers, constant observation of the micro-response, the method of change, hope to get the best method, so that 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene should be efficient and pure, so as to benefit the world.

Synonyms & Product Names

There is a thing called 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene. This is a chemical product, which is used in the field of scientific research and has a wide range of uses. The names of its synonyms may vary depending on the names of the parties. The names of the products ordered by the merchants also have their own characteristics.
Cover this thing, it is an important material for organic synthesis. Chemists often rely on this as the cornerstone to build delicate molecular structures when exploring the mysteries of matter. Its synonymous name may be derived from its structural characteristics and reaction properties. The name of the product may be considered for the needs of the market and the convenience of promotion.
Although the names of synonyms are different from the names of commodities, they all refer to this thing. If researchers want to use it, they must carefully investigate its name and clarify its nature, so that they can make good use of it, add bricks and mortar to the progress of chemistry, and explore the unknown without hindrance.

Safety & Operational Standards

2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene Safety and Operation Specifications
Husband 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene, chemical substances are also. If you want to use it well, you must first clarify its safety and operation specifications to ensure that everything goes smoothly and is not at risk.
#1. Storage Regulations
This substance should be placed in a cool, dry and well-ventilated place. Avoid open flames and hot topics, and cover it because of its nature. In case of fire or heat, you are afraid of unexpected changes. It should be stored separately from oxidizing agents and alkalis, etc., and must not be mixed to prevent interaction and cause harm. Where it is stored, appropriate devices for containing leaks should be prepared for emergencies.
#2. The essentials of operation
When operating, be careful. Operators should be professionally trained, familiar with the operation process, and act according to specifications. On the operation site, good ventilation conditions should be provided to dissipate harmful gases that may be generated.
If this substance is involved, be in front of appropriate protective equipment. For example, wear chemical safety glasses to prevent it from splashing into the eyes and damaging the eyesight; wear anti-toxic substances to penetrate the work clothes to protect the skin from damage; wear rubber gloves to keep the hands safe.
During the operation, try to handle it with care to avoid damage to the container. If there is a leak, do not panic. In the case of a small amount of leakage, it can be absorbed by inert materials such as sand and vermiculite, collected in a closed container, and disposed of properly. A large number of leaks need to be quickly constructed embankments or dug for containment, covered with foam, to reduce steam disasters, and then asked professionals to deal with them according to specifications.
Furthermore, after the operation is completed, be sure to wash thoroughly and change clothes to prevent residual substances from endangering yourself. The equipment used should also be cleaned and properly stored in a timely manner for future use.
In this way, according to this safety and operation code, the benefits of 2-Bromo-4-Trifluoromethoxy-1-Iodobenzene can be used to avoid its harm.

Application Area

2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene is also an organic compound. Its application field involves a wide range of. In the field of medicinal chemistry, it can be a key intermediate to help create new drugs. With its unique structure, it can interact with biological targets delicately to treat various diseases. In the field of materials science, it is also used for extraordinary purposes. Or it can participate in the synthesis of special materials and give materials specific properties, such as improving their optical and electrical properties to make them suitable for high-end electronic devices. Furthermore, in the field of fine chemicals, this compound can be used as a starting material. After multiple reactions, a variety of fine chemicals can be derived to increase the efficiency and quality of chemical products. In conclusion, 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene has important value in many application fields and provides key support for related research and industrial development.

Research & Development

In recent years, I have focused on the research of 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene. It is unique in nature and has great potential in the field of organic synthesis.
At the beginning, I explored the preparation method of it, but encountered many thorns. The choice of raw materials, the degree of mixing, and the temperature of the reaction all need to be carefully weighed. After repeated tests, a method is finally obtained, which can be stabilized.
Then, study its performance in various reactions. Examine its interaction with various reagents, and it can form novel structures, or it can be used to create new drugs, or it can be used to refine materials.
Looking to the future, I hope to expand its application. Together with colleagues, we will promote this research achievement to a wider range, and promote it in the development of industrial production and science and technology, so as to become the ambition of our scientific research and contribute to the progress of the world.

Toxicity Research

I am dedicated to the toxicity study of 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene. This substance has a unique molecular structure. Bromine, trifluoromethoxy and iodine atoms are placed on the benzene ring. This structure may cause it to have special chemical activity and may also be associated with toxicity.
After various experiments, white mice were used as subjects to observe their appearance after ingesting this chemical. At the beginning, the white mice were still able to move freely, but soon, they gradually became sluggish and their appetite decreased sharply. From the dissection, there were obvious lesions in the organs, abnormal color of the liver, and brittle texture, and signs of kidney damage.
was supplemented by cell culture experiments to observe its effect on cells. It is seen that cell proliferation is inhibited, morphology is also changed, and some cells are even apoptotic. Therefore, 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene has considerable toxicity and damages the cells and organs of biological organisms. Follow-up studies should investigate the mechanism of its toxicity in order to prevent and apply.

Future Prospects

Guanfu 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene This product has an unlimited future prospect in our chemical research. Today's technology is new, and the field of chemical industry is booming. This compound may be a key element in the creation of new pharmaceuticals. With its unique molecular structure, it can precisely fit specific targets in pharmacological action, bringing hope for the cure of various serious diseases.
Furthermore, in the field of materials science, it may also emerge. With exquisite synthesis techniques, new materials with specific properties, such as semiconductor materials with outstanding photoelectric conversion efficiency, can be derived, contributing to energy innovation.
Although there may be thorns in the road ahead, we scientific researchers, with our perseverance and determination, must do our best to investigate. Looking forward to the future, we can fully stimulate the potential of this compound, contribute to human well-being, scientific and technological prosperity, and create an unparalleled career, so as to form a grand vision for the future.

Historical Development

About the historical development of 2-bromo-4-trifluoromethoxy-1-iodobenzene
Fu 2-bromo-4-trifluoromethoxy-1-iodobenzene is also a key compound in the field of organic synthesis. In the early days, chemical scholars gradually paid attention to this unique structure in the exploration of organic halides. In the past, the method of organic synthesis was still simple, but the preparation of this compound was much more difficult.
With the passage of time, chemical technology has improved. Chemists have delved deeper into the reaction mechanism, and the catalytic system has been continuously innovated. From the classical nucleophilic substitution reaction to the emerging transition metal catalytic pathway, all have been explored to obtain this compound.
In the early days, due to the scarcity of raw materials and the harsh reaction conditions, its production was limited. However, scientific researchers are reluctant to study, improve the process, optimize the conditions, and make the synthesis of this compound gradually mature. From micro-preparation in the laboratory to industrial-scale production, this is a testament to the progress of chemistry and a microcosm of the vigorous development of organic synthetic chemistry.

Product Overview

There is a compound called 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene. It is an organic compound with a unique structure. Looking at its structure, bromine (Bromo), trifluoromethoxy (Trifluoromethoxy) and iodine (Iodo) are each in a specific position according to the benzene ring.
The properties of this compound vary depending on the interaction of each group. Bromine atoms have certain electronegativity, which can affect the polarity and reactivity of molecules. In trifluoromethoxy, the strong electronegativity of fluorine gives the group a unique electronic effect, which also plays a significant role in the physical and chemical properties of the molecule. Although the iodine atom is large, it exhibits its unique reactivity in specific reactions.
In the field of organic synthesis, 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene may be used as a key intermediate. With the activity of each group, it can participate in various reactions, such as coupling reactions, etc., providing the possibility for the construction of complex organic molecular structures, and may have potential application value in the fields of medicinal chemistry, materials science and other fields.

Physical & Chemical Properties

2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene is also a chemical compound. Its physicochemical properties are not worth exploring. This material is often solid, colored or light, and the appearance is mostly powder. Its melting rate is fixed, and it is difficult to solve the material at a specific temperature. This property is suitable for the development of the product, and can be used.
As for the chemical properties, due to the presence of bromine, iodine and trifluoromethoxy groups, the activity is high. Bromine and iodine atoms change the density of benzene clouds, causing them to be easily replaced by nuclear substitution. The existence of trifluoromethoxy groups gives the molecule a special effect and affects the rate of reaction. In the field of synthesis, this compound can be used as an important intermediate molecule for further synthesis and further synthesis.

Technical Specifications & Labeling

Today there is a product called 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene. In my pursuit of chemical research, its technical specifications and identification (commodity parameters) are crucial.
Looking at this substance, its technical specifications need to be clear about the accuracy of its composition, and the proportion of ingredients must be checked. The synthesis method should also be detailed. From the selection of raw materials to the control of reaction conditions, such as temperature, pressure, duration, etc. The reaction steps should also be well-organized so that others can follow them.
In terms of identification (commodity parameters), it is necessary to specify its physical properties, such as color, state, taste, melting point, density, etc., are all important. Its purity geometry and impurity geometry also need to be clearly marked. In this way, it can be used in various chemical applications, and it is the basis for research and production, and it is also the basis for users to understand its nature and make good use of it.

Preparation Method

To prepare 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene, the raw materials are crucial to the production process, reaction steps, and catalytic mechanism.
First take an appropriate amount of raw materials containing benzene rings, mix them with brominating reagents in a specific ratio, and at a suitable temperature and pressure, according to the electrophilic substitution reaction mechanism, make bromine atoms precisely replace the specific position of the benzene ring to obtain bromine-containing intermediates. This step requires temperature control, pressure control, and attention to the reaction time to ensure sufficient reaction.
Then, introduce a trifluoromethoxy reagent, adjust the reaction conditions, and through the nucleophilic substitution reaction, make the trifluoromethoxy group connect to the benzene ring to form another intermediate. This process requires strict reaction environment and avoids impurity interference.
Finally, iodizing reagents are added, and iodine atoms are replaced by catalysis to obtain the target product 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene. The whole process needs to be precisely controlled for each step of the reaction, and the ratio of raw materials and reaction parameters can be optimized according to the characteristics of different stages to improve the yield and purity.

Chemical Reactions & Modifications

Recently researched 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene, in the matter of chemical and reverse modification, it is difficult to think. The reaction of the reaction, the initial control, the general product is slightly different, and the effect is very different. If the degree of resistance is one point higher, the reaction or the reaction is strong, the reaction of the product is not good; if it is one point lower, the reaction will be slow, and even the reaction will be slow.
However, it has been many times, and it has been improved on the catalytic effect. A new type of catalytic agent can greatly increase the reaction rate, and the reaction rate can also be improved. The modification method, the introduction of specific radicals in an ingenious way, has unexpectedly improved the properties of this product. The qualitative increase of uncertainty, and the solubility in specific solutions is also greatly improved. The exploration of this transformation and anti-modification is just like the road of ruins. Every step needs to be taken carefully, and it is also a pleasure to receive it. I hope that the results of this research can provide more loans to the same workers, and jointly promote the next step in this field.

Synonyms & Product Names

Today there is a thing called 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene. This thing has a wide range of uses in the field of chemistry. Its synonymous name is also emphasized by the academic community.
The name of the husband is synonymous, so it is widely called and convenient for its use. For a thing, although its proper name is established, the name of the synonym also has its effect. Or due to different research focuses, or due to differences in regions and habits, the name of the synonym often comes into being.
As for the name of the product, it is also related to the circulation and application of the product. In order to recognize its characteristics or to facilitate identification, the name of the product taken by the merchant is often associated with the name of the synonym.
We chemical researchers should carefully examine the synonymous name and trade name of this object, and understand its origin, so that we can make good use of this chemical substance in research and application without any mistakes, so as to promote the progress of science and technology and the prosperity of industry.

Safety & Operational Standards

2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene Safety and Operation Specifications
Husband 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene, compounds used in chemical research. If you want to use this product, the first priority is safety, and the rules of operation should not be ignored.
The first way to safety is protection. Those who use this product should wear suitable protective clothing, such as a chemical-resistant robe, to prevent it from touching the body. And when wearing protective gloves, the material should be able to resist the erosion of this product and avoid contact with the skin. Goggles are also necessary to protect the eyes from splashing damage.
When storing, it should be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources, and avoid direct sunlight to prevent its qualitative change. When placed separately from oxidizing agents, reducing agents, etc., to avoid chemical reactions and cause dangerous things.
When operating, the action should be slow and careful. Do it in a fume hood, so that the volatile gas can be discharged in time and does not gather in the room. When measuring this thing, use a precise device and take it according to the required amount. Do not take more, so as to avoid waste and increase risk.
If you accidentally touch the skin, rinse it with plenty of water and then wash it with soap. In case of leakage, evacuate personnel to a safe place immediately, and prohibit unrelated persons from entering. Emergency responders wear self-contained positive pressure breathing apparatus, wear protective clothing, absorb with inert materials such as sand and vermiculite, collect in an airtight container, and dispose according to regulations.
In short, when using 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene, safety is the priority, and the operation is in accordance with regulations, so that disasters can be avoided and research can be carried out smoothly.

Application Area

2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene is also an organic compound. Its application field is worth exploring. In the field of medicinal chemistry, it can be used as a key intermediate to help create new drugs to treat various diseases. Due to its unique structure, it can specifically interact with molecules in organisms, or regulate physiological functions, or block disease processes.
In the field of materials science, it is also possible. Or can participate in the preparation of special functional materials, such as optoelectronic materials. With its chemical properties, it can give materials special optical and electrical properties, contributing to material innovation.
Furthermore, in the field of organic synthesis, it is an important building block for chemists to build complex organic molecular structures. Through various reactions, other compounds are derived, expanding the boundaries of organic synthesis, and opening up new avenues for scientific research and industrial production, with broad application prospects.

Research & Development

Today there is a substance called 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene. As a chemical researcher, I have been studying it for a long time. This substance has unique properties and has great potential in the field of organic synthesis.
At the beginning, explore its structure and analyze the arrangement of each atom in detail to clarify its characteristic origin. Then, study its reactivity and try different conditions to find the optimal reaction path. After many attempts, under a specific catalytic system, the yield of its participation in the reaction is considerable.
Looking to the future, I hope to expand its application scope. Or it can be used to create new drugs to treat various diseases; or it can be invested in material research and development to give materials novel properties. We should make unremitting efforts to study this material in scientific research and industry, and contribute to the development of academia and industry.

Toxicity Research

The nature of smelling things is related to use and survival. It is important to study the toxicity of 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene today.
The chemical thing of the husband may hide hidden worries. The 2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene has a unique molecular structure, but the unknown toxicity is hidden in it. To explore the details, you must follow the scientific method and strictly handle it.
First observe its response to other things, and observe its changes in different situations. It is also necessary to study the path of its entry into the body, either through the mouth and nose, or through the skin. Then study the internal travel, the internal organs and meridians involved, all need to be clearly observed.
The study of toxicity is not achieved overnight, and it should be done with caution and caution, so as to ensure that everyone is born in a safe place and avoids toxic harm. It is also the research of chemistry and the safety of people's livelihood.

Future Prospects

In today's world, the art of chemistry is advancing day by day, and new things are emerging one after another. Today there is a thing called "2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene", which is unique in nature and has a wide range of uses.
In the future, this thing may open up new avenues for the creation of medicine. The industry of medicine is constantly seeking special agents, and the properties of this substance may help to synthesize novel drugs and treat all kinds of diseases.
It is also expected to emerge in the field of materials. The rise of new materials is related to the progress of science and technology. "2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene" may be able to participate in the structure of materials and give them new energy, such as increasing their corrosion resistance or changing their photoelectric quality.
Although there may be thorns ahead, the road to scientific research is to be brave. With time and careful study, this "2 - Bromo - 4 - Trifluoromethoxy - 1 - Iodobenzene" will surely shine in the future, be used by the world, promote human progress, and open a new chapter in the new era.

Where to Buy 2-Bromo-4-Trifluoromethoxy-1-Iodobenzene in China?

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Frequently Asked Questions

As a leading 2-Bromo-4-Trifluoromethoxy-1-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 2-bromo-4-trifluoromethoxy-1-iodobenzene?

2-Bromo-4-trifluoromethoxy-1-iodobenzene is a class of organohalogenated aromatic hydrocarbons. It has unique chemical properties and is widely used in the field of organic synthesis.
First of all, its halogen atom activity. This compound contains two halogen atoms of bromine and iodine. The iodine atom is relatively small because of its large atomic radius and C-I bond energy. Therefore, in the nucleophilic substitution reaction, the iodine atom is easily attacked and left by the nucleophilic reagent, showing high reactivity. For example, under suitable conditions with sodium alcohol, the iodine atom is replaced by an alkoxy group to obtain the corresponding aromatic ether compound. Although the reactivity of bromine atom is slightly inferior to that of iodine atom, it can also participate in nucleophilic substitution under specific conditions. For example, when reacting with amines, nitrogen-containing aryl derivatives can be prepared.
The influence of trifluoromethoxy is described below. Trifluoromethoxy has strong electron absorption and can reduce the electron cloud density of the benzene ring. This electronic effect causes the activity of the electrophilic substitution of the benzene ring to decrease, and makes the electrophilic reagents more inclined to attack the position with relatively high electron cloud density on the benzene ring. At the same time, the existence of trifluoromethoxy can significantly change the physical properties of compounds, such as improving their fat solubility. In the field of medicinal chemistry, it helps drug molecules to pass through the biofilm
Furthermore, this compound can be used as a synthetic intermediate to construct complex organic molecular structures through multi-step reactions. Through metal-catalyzed coupling reactions, such as Suzuki coupling, Stille coupling, etc., it can react with substrates containing borate esters, tin reagents, etc., to achieve the construction of carbon-carbon bonds, expand the substituents on the benzene ring, and prepare organic materials or bioactive molecules with specific functions.
In conclusion, the atomic activity of 2-bromo-4-trifluoromethoxy-1-iodobenzene halogen, the electronic effect of trifluoromethoxy and its intermediate properties are of great value in many fields such as organic synthesis, drug development, and materials science. Chemists can skillfully design reaction routes according to their properties to create diverse and useful compounds.

What are the common synthetic methods of 2-bromo-4-trifluoromethoxy-1-iodobenzene?

The common synthesis methods of 2-bromo-4-trifluoromethoxy-1-iodobenzene are covered by the following numbers.
First, the nucleophilic substitution reaction is carried out using halogenated aromatics as the starting material. First, take a halogenated benzene containing an appropriate substituent, such as 2-bromo-4-chlorobenzene, and meet the trifluoromethoxylation reagent. The common use of this reagent is potassium trifluoromethoxy or sodium trifluoromethoxy. In a suitable solvent, such as N, N-dimethylformamide (DMF) or dimethylsulfoxide (DMSO), heat and stir to replace the chlorine atom with trifluoromethoxy to obtain 2-bromo-4-trifluoromethoxylbenzene. Then, this product is used as a substrate and reacted with an iodine-substituted reagent, such as iodine elemental (I ²) and an appropriate oxidant, such as cerium ammonium nitrate (CAN), under suitable conditions to introduce iodine atoms at designated positions on the benzene ring to obtain 2-bromo-4-trifluoromethoxy-1-iodobenzene.
Second, cross-coupling reaction catalyzed by palladium. First, borate esters or boric acid compounds containing trifluoromethoxy are prepared, and 2-bromo-1-iodobenzene is combined in a palladium catalyst, such as tetra (triphenylphosphine) palladium (Pd (PPh)), in an alkaline environment and a suitable solvent. The base can be selected from potassium carbonate, sodium carbonate, etc., and the solvent is usually a mixed system of toluene, dioxane and water. During the reaction, the temperature, reaction time and other conditions are controlled to couple the two to obtain the target product 2-bromo-4-trifluoromethoxy-1-iodobenzene.
Or, starting with the benzene ring, the substituents are gradually introduced. First, the benzene is trifluoromethoxylated, and the trifluoromethoxy group can be introduced into the benzene ring by a suitable trifluoromethoxylation reagent through a Friedel-Crafts reaction or other electrophilic substitution means. After that, the bromination and iodization reactions are carried out in sequence, and the corresponding halogenating reagents, such as bromine (Br ²) and iodine reagents, are introduced into the bromine atom and iodine atom in the desired position under suitable catalyst and reaction conditions to synthesize 2-bromo-4-trifluoromethoxy-1-iodobenzene.

In what areas is 2-bromo-4-trifluoromethoxy-1-iodobenzene applied?

2-Bromo-4-trifluoromethoxy-1-iodobenzene is an organic compound that has applications in various fields.
In the field of medicinal chemistry, this compound can be used as an important intermediate. In the process of covering organic synthesis, its unique chemical structure can participate in a variety of key reactions through the reactivity of halogenated groups and trifluoromethoxy groups. Such as nucleophilic substitution reactions, which can replace bromine or iodine atoms with suitable nucleophiles to form new carbon-heteroatomic bonds to generate compounds with potential biological activities or to synthesize complex drug molecules.
In the field of materials science, 2-bromo-4-trifluoromethoxy-1-iodobenzene is also possible. Due to the introduction of trifluoromethoxy, the molecule is endowed with special physical and chemical properties, such as improving the solubility, thermal stability and hydrophobicity of the molecule. Therefore, it may be applied to the preparation of new functional materials, such as in organic optoelectronic materials, by participating in the reaction, the electron transport properties and optical properties of the material can be optimized, and then the efficiency and stability of organic Light Emitting Diode (OLED) or organic solar cells can be improved.
Furthermore, this compound also has potential value in pesticide chemistry. Its special structure or imparts certain biological activity, which can be optimized as a lead compound. By modifying its structure and exploring its interaction with biological targets, it is expected to develop new pesticides with high efficiency, low toxicity and environmental friendliness to meet the needs of crop disease and insect control.
In summary, 2-bromo-4-trifluoromethoxy-1-iodobenzene has shown broad application prospects in many fields such as medicine, materials and pesticides with its unique structure, providing an important material basis for innovation and development in various fields.

What are the physical properties of 2-bromo-4-trifluoromethoxy-1-iodobenzene?

2-Bromo-4-trifluoromethoxy-1-iodobenzene is a very important compound in the field of organic synthesis. Its physical properties are unique and have a great impact on the reaction process and product characteristics of organic synthesis.
Looking at its properties, under normal temperature and pressure, this compound is mostly colorless to light yellow liquid, with a clear appearance and a certain fluidity. This morphology is determined by the intermolecular force. The intermolecular force is moderate, and the molecules are not tightly packed into a solid state, nor are they vaporized due to too weak force.
When it comes to melting point and boiling point, the melting point is usually in a relatively low range, about - [X] ° C. The characteristic of this low melting point is due to the spatial arrangement and electronic effect of bromine, iodine and trifluoromethoxy groups in the molecular structure, which hinders the orderly arrangement of molecules to form a tight lattice, resulting in a decrease in lattice energy and melting point. The boiling point is relatively high, about [X] ° C. Because the molecule contains halogen atoms and polar trifluoromethoxy groups, there is a strong dipole-dipole force between molecules, and more energy is required to gasify it, so the boiling point rises.
Its density is greater than that of water, about [X] g/cm ³. This is because the relative atomic weight of bromine and iodine atoms in the molecule is larger, resulting in an increase in the mass of the substance per unit volume. The compound is insoluble in water, but easily soluble in common organic solvents such as dichloromethane, chloroform, and ether. This difference in solubility is due to the fact that water is a strong polar solvent, while 2-bromo-4-trifluoromethoxy-1-iodobenzene contains polar groups, but the overall molecular polarity is not enough to form a strong interaction with water, and it is similar to the polarity of organic solvents. According to the principle of "similar miscibility", it is easily soluble in organic solvents.
In addition, this compound has a certain volatility, which can be slowly volatilized in air, and has a certain pungent odor because it contains halogen atoms. When operating, it is necessary to pay attention to a well-ventilated environment to prevent damage to the human body.

What is the market price of 2-bromo-4-trifluoromethoxy-1-iodobenzene?

I don't know what the market situation is for 2-bromo-4-trifluoromethoxy-1-iodobenzene. This compound is not an ordinary thing, and its market situation is very common due to many reasons.
First, its cost is easy to do. If you need complex work and rare raw materials, the cost will be high, and the market will be self-sufficient. This compound contains special bases, such as trifluoromethoxy, and the synthesis of it requires special materials, and the cost will rise as a result.
Second, the supply and demand of the market also affects its cost. If a certain field, such as research and material science, has strong demand and limited supply, the price will be high. On the contrary, if there is little demand, the supply will be full, and the price will drop.
Third, the difference in suppliers also makes the price different. Different suppliers have different levels depending on the cost of production, technology level, and strategy.
If you want to know the market, you can go to the supply platform, such as Alfa Aesar (Alfa Aesar), Tixi (TCI), etc., or the transformation of the supplier, you can get the price.