2-Bromo-5-Fluoroiodobenzene

Fengxi Chemical

Specifications

HS Code	650478
Chemical Formula	C6H3BrFI
Molecular Weight	303.896 g/mol
Appearance	Typically a colorless to light - yellow liquid
Boiling Point	Approximately 230 - 240 °C (est.)
Density	Estimated to be relatively high due to heavy halogens, around 2.3 - 2.5 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform, toluene
Reactivity	Reactive towards nucleophiles due to the presence of halogen atoms

As an accredited 2-Bromo-5-Fluoroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 2 - bromo - 5 - fluoroiodobenzene packaged in a sealed glass bottle.
Storage	2 - bromo - 5 - fluoroiodobenzene should be stored in a cool, dry, well - ventilated area away from sources of heat and ignition. Keep it in a tightly sealed container, preferably made of glass or a suitable chemical - resistant material. Store it separately from oxidizing agents, reducing agents, and reactive substances to prevent potential chemical reactions.
Shipping	2 - bromo - 5 - fluoroiodobenzene is shipped in sealed, corrosion - resistant containers. Packaging adheres to international chemical transport regulations to prevent leakage during transit, ensuring safety of handlers and the environment.

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General Information

Historical Development

Fu 2 - Bromo - 5 - Fluoroiodobenzene is also a product of organic chemistry. The process of its research and development is of far-reaching significance. In the past, the way of organic synthesis was not as delicate as it is today, and all the sages dedicated their efforts to exploring the synthesis of this thing.
At the beginning, I only knew the nature of its chemistry, but it was difficult to make it. The craftsmen worked hard and tried all kinds of methods, either because of the difficulties of conditions or because of the failure of the theory. However, everyone was not discouraged and continued to study.
After long-term grinding, the chemical theory has gradually enriched, and the technology has also become more and more mature. Scholars have delved into the reaction conditions, raw material ratio, etc., and finally obtained the synthesis method. This process is like clearing the clouds to see the sun, and after hardships, it will be bright. Since then, the preparation of 2-Bromo-5-Fluoroiodobenzene has gradually become routine, paving the way for subsequent applications in many fields and opening a new chapter in organic chemistry research.

Product Overview

Today there is a substance called 2 - Bromo - 5 - Fluoroiodobenzene. Its shape is crystalline, or colorless to light yellow. Looking at its structure, the benzene ring is based, and bromine, fluorine and iodine atoms are attached to it. The layout is consistent and the structure is exquisite.
This substance is used in various fields of chemistry and has a wide range of uses. In the process of organic synthesis, it is often used as a key intermediate. With its unique structure, it can lead to various reactions and pave the way for the creation of a variety of organic compounds.
When preparing, it needs to follow a precise method. Or through a halogenation reaction, bromine, fluorine and iodine can be connected to the benzene ring in an orderly manner. During operation, the reaction conditions are strictly controlled, such as temperature, solvent, catalyst, etc., which are all critical to success or failure.
However, this substance also has risks. It is toxic and corrosive to a certain extent, and the operator must be cautious, well-protected, and follow the norms to ensure safety and smooth research and production.

Physical & Chemical Properties

2 - Bromo - 5 - Fluoroiodobenzene is an organic compound. Its physical properties are mostly liquid at room temperature and have a special odor. Due to the presence of halogen atoms in the molecular structure, the relative density is greater than that of water. Its boiling point is affected by intermolecular forces, and the molecular polarity is enhanced due to halogen atoms, and the boiling point is higher.
In terms of chemical properties, halogen atoms have high activity. Bromine and iodine atoms can undergo nucleophilic substitution reactions. In case of nucleophilic reagents, halogen atoms are easily replaced. Due to the high electronegativity of fluorine atoms, the electron cloud density of benzene rings changes, which affects its electrophilic substitution reaction activity. This compound has a wide range of uses in the field of organic synthesis and can be used as a key intermediate to prepare complex organic molecules and promote the development

Technical Specifications & Labeling

Today there is a product called 2 - Bromo - 5 - Fluoroiodobenzene. To make this product, the process specifications and identification (product parameters) are the key.
Its process specifications need to be based on precise methods. The proportion of materials must be matched, and the reaction conditions should be cautious. If the temperature is controlled, the quality will change if it is too high, and it should be difficult if it is too low. The reaction time must also be just. If it is short, it will not be finished, and if it is long, it may damage its properties.
In terms of identification (product parameters), the appearance and luster are obvious, and the impurity content must be small. The standard of its purity is related to the quality. Accurate measurement to meet the needs of use. Only in this way can we produce good products, which are beneficial to the user and have a reputation for the industry.

Preparation Method

This product of 2 - Bromo - 5 - Fluoroiodobenzene requires the raw materials and the preparation method. The raw materials are selected to be pure to ensure the quality of the product.
The method of preparation, first take an appropriate amount of fluorobenzene, use the method of bromination to make it adapt to a specific environment, and control its temperature and pressure. This is the first step. Bromine into fluorobenzene to form an intermediate body.
Next, add it by the method of iodization. At this step, pay attention to the mixing of reagents and the rate of response. Control the reaction process to adapt the intermediate body to the iodine agent to obtain 2 - Bromo - 5 - Fluoroiodobenzene.
In order to maintain the purity of the product, it needs to be refined. By chromatography or recrystallization, the heterogeneity is removed and the purity is retained. In the whole process of this system, the temperature, pressure, time and agent are controlled, and the catalytic mechanism of Jianliang is established to promote the reaction and yield. In this way, a good product 2 - Bromo - 5 - Fluoroiodobenzene can be obtained.

Chemical Reactions & Modifications

Today there is a thing, named 2 - Bromo - 5 - Fluoroiodobenzene, in the field of chemistry, its reaction and modification are worth studying. The reaction of chemistry, such as the symmetry of yin and yang, is endlessly variable. This compound has a unique structure and is atomic dependent, just like the stars in the sky.
To seek the beauty of its reaction, all conditions should be investigated. Temperature and solvent are the main factors. When the temperature is increased, the molecules are active, and the reaction speed changes. The properties of solvents also affect the polarity and non-polarity, and each has its own use.
As for modification, new groups can be introduced to change their properties. Or increase its activity, or change its physical characteristics. With ingenious methods, the atoms are rearranged and the structure is renewed. In this way, you can get the things you need, which can be used in various fields, medicine, materials, and all can benefit. Studying this path, such as exploring the secrecy, hoping to gain something, will contribute to the progress of chemistry.

Synonyms & Product Names

2 - Bromo - 5 - Fluoroiodobenzene, the synonym and trade name of this substance, is quite important. In my field of chemical research, it is crucial to know its different names.
Fu 2 - Bromo - 5 - Fluoroiodobenzene, or 5 - fluoro - 2 - bromoiodobenzene. This is because the naming rules can be determined according to different focuses. From a structural perspective, both refer to this particular organic compound. It is often used as a key intermediate in organic synthesis.
The trade names are also different, but they all refer to this unique chemical. Or because of its use and production process, the trade names are diverse. In the scientific research experiment, the accurate cognition of its synonyms and trade names can be used without error and promote the progress of the research, so as not to be confused by the title, mislead the process of the experiment, and lose the direction of the research.

Safety & Operational Standards

2 - Bromo - 5 - Fluoroiodobenzene is an important chemical compound in chemical synthesis. Its safety and operating standards are related to the success or failure of the experiment and the safety of personnel.
For storage, this compound should be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources and prevent direct sunlight. Because of its certain chemical activity, it should be stored separately from oxidants, acids, alkalis, etc., and should not be stored in combination to avoid chemical reactions and cause danger.
During operation, the experimenter must take protective measures. Wear suitable protective glasses to prevent the compound from splashing into the eyes and causing eye damage. Wear protective clothing to avoid skin contact. At the same time, wear protective gloves and choose materials that can effectively block the compound.
When taking 2-Bromo-5-Fluoroiodobenzene, it should be done in a fume hood. Because the compound may evaporate and produce harmful gases, the fume hood can discharge it in time to reduce indoor air pollution and ensure the safety of the experimenter's breathing. The use process requires the use of clean and dry appliances to prevent impurities from mixing and affecting the quality of the compound, and the action should be precise and rapid to avoid unnecessary waste and volatilization.
If you accidentally come into contact with 2-Bromo-5-Fluoroiodobenzene, you should take appropriate measures immediately. If it comes into contact with the skin, quickly rinse with a large amount of flowing water for at least 15 minutes, and then seek medical attention in time. If splashing into the eyes, immediately lift the eyelids, rinse thoroughly with plenty of flowing water or normal saline for at least 15 minutes, and go to the hospital as soon as possible.
In short, the safety and operating standards of 2-Bromo-5-Fluoroiodobenzene must not be taken lightly, and follow the rules to ensure the safety and smooth progress of the experiment.

Application Area

2 - Bromo - 5 - Fluoroiodobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help create new drugs. With its unique structure, it can interact precisely with molecules in organisms, or it can lead to specific therapeutic drugs.
In the field of materials science, it also has its uses. Or it can participate in the synthesis of functional materials through specific reactions. The characteristics of this compound may endow materials with unique optical and electrical properties, contributing to the research and development of advanced materials.
In addition, in organic synthetic chemistry, it is often used as the cornerstone of building complex organic molecules. With its lively chemical activity, chemists can use various reactions to build diverse molecular structures, expand the variety of organic compounds, and further promote the progress of chemical science.

Research & Development

In recent years, I have specialized in the field of chemistry, specializing in the product 2 - Bromo - 5 - Fluoroiodobenzene. This compound has a unique structure and has extraordinary potential in the process of organic synthesis.
At the beginning, the preparation method was difficult. The raw materials are rare, the reaction conditions are harsh, and the yield is often low. However, I did not give up, I devoted myself to research, and searched the classics all over, imitating the strength of ancient people in seeking knowledge, and tried new methods many times.
After months of work, I finally got the path of optimization. The reaction medium is improved, the temperature is precisely controlled, and the yield is gradually increasing. And the purity of this product has also been refined, reaching a very high level.
Looking at its application, it has emerged in many fields such as drug research and development, material creation, etc. It assists in the construction of new drug molecules and endows materials with specific properties.
I believe that in time, 2-Bromo-5-Fluoroiodobenzene will shine, adding to the progress of chemistry, leading a new way of synthesis and creating a new situation.

Toxicity Research

The study of poisons is related to the safety of people's livelihood. There are substances today, called 2-Bromo-5-Fluoroiodobenzene. This is a chemical substance, and the study of its toxicity cannot be ignored.
To understand its toxicity, we should study its properties. Looking at the structure of its molecules, atoms of bromine, fluorine and iodine are attached to the benzene ring. The quality of the benzene ring has a certain activity, and the connection of these atoms may change its chemical properties and increase its toxicity.
In the context of experiments, take animals as models and observe their reactions. If it enters the body, it may damage its internal organs and disrupt its physiological order. Or cause changes in cells and cause various diseases. And this thing in the environment, or long-lasting and difficult to eliminate, harm the ecology.
Therefore, its toxicity is studied, in order to ensure the health of all living beings and protect the harmony of nature. It is necessary to study its nature in detail to prepare for countermeasures, and not to slack a little.

Future Prospects

Fu 2 - Bromo - 5 - Fluoroiodobenzene is becoming more and more important in today's chemical research. Although it is currently or not in its prime, its future prospects are really promising.
Looking at its properties, it has unique chemical characteristics and can be a key raw material for many reactions. As a result, it may open up new avenues in the field of organic synthesis, and research assistants can obtain more delicate products.
In industrial applications, with time and in-depth investigation, it may become an essential agent for efficient synthesis, reducing costs and increasing benefits. Medical research, or as a result of new drug precursors, to add to the healing of diseases and diseases.
Even if there are current obstacles, the scientific researchers uphold the perseverance and unremitting research. I am convinced that with time, 2 - Bromo - 5 - Fluoroiodobenzene will be able to bloom its brilliance, expand infinite possibilities and develop grand visions in the scientific journey of the future.

Where to Buy 2-Bromo-5-Fluoroiodobenzene in China?

As a trusted 2-Bromo-5-Fluoroiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 2-Bromo-5-Fluoroiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-bromo-5-fluoroiodobenzene?

2-Bromo-5-fluoroiodobenzene is an organic compound. Its main uses are quite extensive, and it is often used as a key intermediate in the field of organic synthesis.
First, in the field of medicinal chemistry, this compound can be used as the cornerstone for constructing new drug molecular structures. The unique electronic properties and spatial effects of bromine, fluorine and iodine atoms on the benzene ring can endow the synthesized drug with specific biological activities and pharmacological properties. After chemical modification and reaction, the interaction between the drug and the biological target can be precisely regulated, thereby improving the efficacy, selectivity and safety of the drug. For example, by forming halogen bonds with specific amino acid residues, the conformation and function of proteins can be affected to achieve intervention in disease-related biological processes.
Second, in the field of materials science, 2-bromo-5-fluoroiodobenzene also has important applications. It can participate in the preparation of functional organic materials, such as organic optoelectronic materials. With the properties of benzene rings and halogen atoms, the electronic transport properties, light absorption and emission properties of the materials can be adjusted. The obtained materials may be applied to organic Light Emitting Diodes (OLEDs), organic solar cells and other devices to improve their photoelectric conversion efficiency and stability.
Furthermore, in the fine chemical industry, this compound can be used to synthesize high-end fine chemicals. Due to its unique structure, it can be converted into various compounds with special functions through a series of chemical reactions, which are used in the production of fine chemical products such as fragrances, coatings, and additives, giving the products unique performance and quality.

What are the physical properties of 2-bromo-5-fluoroiodobenzene?

2-Bromo-5-fluoroiodobenzene is an organic compound. Its physical properties are crucial and of great significance in many fields of chemistry.
Looking at its physical state, under normal temperature and pressure, 2-bromo-5-fluoroiodobenzene is usually in a liquid state. This state makes it fluid. In the chemical reaction system, it can be more easily contacted and mixed with other substances, and then promote the reaction process.
When it comes to color, the compound is generally a colorless to light yellow liquid. The color characteristics can not only help to initially distinguish, but also in some reaction monitoring, the color change may suggest the reaction process and degree.
In terms of boiling point, although the exact boiling point fluctuates depending on specific conditions, it is roughly within a certain range. The boiling point shows the energy required for its transformation from liquid to gaseous state, which is of great significance for distillation, separation and other operations, and can be used to achieve separation from other substances with large boiling points.
Melting point is also one of the important physical properties, which reflects the temperature node of the mutual transformation of solid and liquid states. Understanding the melting point helps to control the appropriate temperature conditions during storage and use to ensure that it is in the required physical state.
In terms of solubility, 2-bromo-5-fluoroiodobenzene has a certain solubility in organic solvents such as dichloromethane, chloroform, ether, etc., but it is difficult to dissolve in water. This solubility characteristic is crucial in the process of organic synthesis, separation and purification, and can be selected according to the solubility of suitable solvents for reaction, extraction and other operations.
Density is another significant physical property. Through density data, it can be accurately measured in experiments and production processes involving volume and quality conversion to ensure that the reaction ratio is appropriate, and improve product quality and experimental accuracy.
2-Bromo-5-fluoroiodobenzene These physical properties are interrelated and affect each other, and have a profound effect on its storage, transportation, use and participation in chemical reactions. It is an indispensable consideration in the research and actual production process of organic chemistry.

Is 2-bromo-5-fluoroiodobenzene chemically stable?

2-Bromo-5-fluoroiodobenzene is one of the organic compounds. The stability of its chemical properties is determined by a variety of factors.
From the perspective of molecular structure, this compound contains three halogen atoms: bromine, fluorine and iodine. Halogen atoms have strong electronegativity, which can cause electronic effects on the benzene ring. Fluorine atoms have a small radius and extremely strong electronegativity, which will reduce the electron cloud density of the benzene ring, especially in the adjacent and para-position of the benzene ring, causing its electrophilic substitution reaction activity to be different from that of the ordinary benzene ring. Although the electronegativity of bromine and iodine atoms is slightly weaker than that of fluorine, it also affects the electron cloud distribution of the benzene ring.
In terms of stability, the bond energy of the carbon-halogen The carbon-fluorine bond energy is extremely high and relatively stable; the carbon-bromine and carbon-iodine bond energy is slightly lower and the relative activity is higher. Therefore, under suitable conditions, the carbon-bromine bond and the carbon-iodine bond may react, causing molecular structure changes.
In common chemical environments, 2-bromo-5-fluoroiodobenzene may maintain a certain stability at room temperature, room pressure and no special reagent action. However, when exposed to high temperature, strong oxidizing agent, strong reducing agent or specific catalyst, it may react chemically. For example, in the nucleophilic substitution reaction, the carbon-halogen bond can be attacked by the nucleophilic reagent, causing the halogen atom to be replaced. In addition, under conditions that can initiate a free radical reaction, the halogen atom may be initiated into a free radical, resulting in a series of chain reactions.
In short, the chemical stability of 2-bromo-5-fluoroiodobenzene is not absolute, and it varies depending on the specific environment and the reagent encountered. Under certain conditions, it may exhibit certain activity and occur various chemical reactions. Therefore, when using or storing this compound, it must be properly disposed of according to its characteristics to ensure safety and stability.

What are 2-bromo-5-fluoroiodobenzene synthesis methods?

2-Bromo-5-fluoroiodobenzene is an important compound in organic synthesis. There are various synthesis methods, which you will describe in detail today.
First, it can be started from halogenated aromatics. First, react with a suitable brominating reagent, such as N-bromosuccinimide (NBS), with a fluoroiodobenzene derivative. In a suitable solvent, such as dichloromethane, in the presence of light or initiator, the bromine atomic energy in NBS selectively replaces the hydrogen atom at a specific position on the benzene ring to obtain the target product 2-bromo-5-fluoroiodobenzene. This reaction condition is mild and the selectivity is high.
Second, metal-catalyzed cross-coupling reaction can be used. The fluorophenylboronic acid derivative is reacted with halogenated bromoiodobenzene under the action of palladium and other metal catalysts. For example, tetra (triphenylphosphine) palladium is commonly used as a catalyst, and potassium carbonate is used as a base to heat the reaction in a mixed system of organic solvents such as toluene and water. This method can effectively construct carbon-carbon bonds and realize the synthesis of target compounds. And metal-catalyzed cross-coupling reactions are widely used in the field of organic synthesis. The substrate has strong applicability and can provide various pathways for product synthesis.
Third, the electrophilic substitution reaction of benzene ring can also be started. Using benzene as the starting material, fluorine atoms are introduced first, then iodine atoms are introduced, and finally bromine atoms are introduced through electrophilic substitution This process requires fine control of the reaction conditions and the amount of reagents, because different substituents on the benzene ring have an impact on the localization effect of subsequent substitution reactions. However, this method is easy to obtain raw materials, and if the conditions are properly controlled, it is also an effective strategy for the synthesis of 2-bromo-5-fluoroiodobenzene.
The above synthesis methods have their own advantages and disadvantages, and the appropriate synthesis path should be comprehensively considered according to the actual situation, such as the availability of raw materials, the difficulty of reaction conditions, and the requirements of product purity.

2-bromo-5-fluoroiodobenzene need to pay attention to when storing and transporting

2-Bromo-5-fluoroiodobenzene is an organic compound. When storing and transporting, many matters need to be paid careful attention.
Let's talk about storage first. Because of its certain chemical activity, it needs to be placed in a cool, dry and well-ventilated place. This environment can prevent its chemical properties from changing due to excessive temperature and humidity, and avoid degradation or reaction with substances in the environment. Furthermore, keep away from fire and heat sources, because it may be flammable, and it is easy to cause fire danger near fire. At the same time, it should be stored separately from oxidants and strong bases to prevent violent chemical reactions. Because the halogen atoms in the structure of 2-bromo-5-fluoroiodobenzene are active, the reaction may be out of control when exposed to oxidants and strong bases. The storage place should also have obvious warning signs to make the contact aware of its potential danger.
As for transportation, it is necessary to ensure that the packaging is in good condition. Use packaging materials that meet safety standards to prevent leakage. If it is a long-distance transportation, it is necessary to carefully check the sealing of the packaging. The temperature and humidity during transportation should be properly controlled to maintain a stable environment. And the transportation vehicle should be equipped with corresponding fire equipment and leakage emergency treatment equipment to prevent accidents from happening and respond in time. Transport personnel also need to be professionally trained, familiar with the properties of 2-bromo-5-fluoroiodobenzene and emergency treatment methods. Pay close attention to the status of the goods during transportation, and take immediate measures if there is any abnormality.