2 Bromo 5 Iodo 3 Methylpyridine

2-Bromo-5-iodine-3-methylpyridine is a crucial intermediate in the field of organic synthesis. It has a wide range of uses and is often used as a key building block in the field of pharmaceutical synthesis to build the core structure of various drug molecules. For example, many compounds with specific biological activities can be precisely constructed by using 2-bromo-5-iodine-3-methylpyridine as the starting material through a series of exquisite chemical reactions, such as nucleophilic substitution and coupling reactions, which are expected to develop new therapeutic drugs or optimize the efficacy and safety of existing drugs.
In the field of materials science, it also shows unique value. Can be used as a precursor to participate in the synthesis of functional materials, such as organic optoelectronic materials. By ingeniously designing the reaction path, 2-bromo-5-iodine-3-methylpyridine can be combined with other specific organic groups, which can endow the material with special optical and electrical properties, and can be used in cutting-edge materials such as Light Emitting Diode and solar cells.
In addition, in the synthesis of pesticides, 2-bromo-5-iodine-3-methylpyridine is also indispensable. Through reasonable chemical modification, pesticide products with high insecticidal and bactericidal activities can be prepared, providing powerful chemical means for pest control in agricultural production and ensuring crop yield and quality. In conclusion, due to its unique molecular structure, 2-bromo-5-iodine-3-methylpyridine plays an indispensable role in many fields, and has far-reaching significance for promoting scientific research and industrial development in related fields.

There are several methods for synthesizing 2-bromo-5-iodine-3-methylpyridine. First, the pyridine derivative can be initiated through the steps of halogenation and methylation. First, take a suitable pyridine substrate, use a brominating agent such as N-bromosuccinimide (NBS), in a suitable solvent, such as dichloromethane, under the action of light or an initiator, carry out a bromination reaction, which can introduce bromine atoms at specific positions in the pyridine ring. Then, under suitable reaction conditions, iodine atoms can be introduced with iodine substitutes, such as potassium iodide and appropriate oxidizing agents. As for the introduction of methyl groups, methylating agents, such as iodomethane and base, can be achieved in a suitable reaction system.
Furthermore, pyridine rings can also be constructed by cyclization from aromatic hydrocarbons containing corresponding substituents. First, aromatic hydrocarbons containing bromine, iodine and methyl positioning groups are prepared, and then the pyridine ring structure is constructed by intramolecular cyclization reactions, such as cyclization reactions catalyzed by transition metals. This process requires fine regulation of reaction conditions, such as temperature, catalyst dosage and ligand selection, to ensure the formation of the target product 2-bromo-5-iodine-3-methylpyridine. In addition, different starting materials and reaction paths have their own advantages and disadvantages, which need to be selected according to actual needs and conditions. Or consider the availability of raw materials, the selectivity of the reaction, the yield, and the difficulty of post-processing to optimize the synthesis route for the purpose of efficient preparation.

2-Bromo-5-iodine-3-methylpyridine is one of the organic compounds. Its physical properties are crucial and related to the scope of many chemical applications.
In terms of its properties, at room temperature, this compound is mostly solid, and its solid state may be crystalline, and whether the crystal shape is regular or not depends on the preparation conditions. This solid state property has its own unique requirements for storage and transportation. It is necessary to pay attention to the control of environmental temperature and humidity to prevent its properties from changing.
The melting point is also an important physical property. After experimental measurement, its melting point is about a specific temperature range. The confirmation of this temperature range is of great significance for identifying the compound and controlling its state change under different temperature conditions. Knowing the melting point can accurately grasp the physical state transition node during the heating or cooling process, and is of great guiding value in the synthesis and purification steps.
The boiling point is also a physical parameter that cannot be ignored. Under specific pressure conditions, its boiling point has corresponding values. The determination of the boiling point helps to understand the degree to which the compound will be converted from liquid to gas when heated, which is a key basis in operations such as distillation and separation. By adjusting the temperature to near the boiling point, the compound can be separated from other substances with different boiling points to achieve the purpose of purification.
In terms of solubility, this compound exhibits different solubility properties in different solvents. In some organic solvents, such as alcohols and ethers, it may exhibit certain solubility, but in water, its solubility may be quite limited. This solubility characteristic is an important consideration when selecting an appropriate reaction medium during chemical synthesis and selecting an appropriate extraction solvent during separation and purification.
Density is also one end of the physical properties of the compound. Accurate determination of its density can help to achieve precise operation in solution preparation, reaction material measurement, etc. According to the density value, a certain mass of the compound can be accurately measured to ensure that the chemical reaction is carried out according to a predetermined stoichiometric ratio, thereby improving the efficiency of the reaction and the purity of the product. The physical properties of 2-bromo-5-iodine-3-methylpyridine, such as their properties, melting point, boiling point, solubility, and density, play a crucial role in the research, synthesis, and application of organic chemistry, and are essential for researchers and chemical practitioners to know and accurately grasp.

2-Bromo-5-iodine-3-methylpyridine is one of the organic compounds. Its chemical properties are quite unique.
In this compound, bromine (Br), iodine (I) and methyl (-CH
) are attached to the pyridine ring. Both bromine and iodine are halogen elements and have active chemical properties. Due to the high electronegativity of bromine atoms, the electron cloud distribution of the pyridine ring can be changed, resulting in the increase and decrease of the electron cloud density of the adjacent and para-sites. During the electrophilic substitution reaction, the adjacent and para-sites are more susceptible to the attack of electrophilic reagents. Although the atomic radius of the iodine atom is large, it can also affect the electron cloud of the pyridine ring, and the carbon-iodine bond connected by iodine is relatively weak, and under certain conditions, it is easy to break and cause substitution reactions.
methyl is attached to the pyridine ring, which is a power supply group, which can increase the electron cloud density of the pyridine ring, making the pyridine ring more electron-rich and easier to react with electrophilic reagents. And the existence of methyl also affects the spatial structure of the molecule and affects its interaction with other molecules.
Under basic conditions, the halogen atom in 2-bromo-5-iodine-3-methylpyridine can undergo nucleophilic substitution reactions. In case of nucleophiles, bromine or iodine atoms can be replaced to form new organic compounds. In some metal-catalyzed reactions, the carbon-halogen bond can be broken, and then participate in the coupling reaction to construct more complex organic molecular structures.
2-bromo-5-iodine-3-methylpyridine has many potential applications in the field of organic synthesis due to the synergistic effect of bromine, iodine and methyl. By virtue of its chemical properties, a variety of organic materials with special functions or pharmaceutical intermediates can be prepared.

2-Bromo-5-iodo-3-methylpyridine is an organic compound that may have applications in chemical, pharmaceutical and other fields. However, it is difficult to answer directly based on the market price. The price of bromo-5-iodo-3-methylpyridine is affected by many factors, and "Tiangong Kaiwu" does not contain the relevant content of the price of this product. Let me explain it in detail as follows.
The first one to bear the brunt is the preparation cost. The preparation process of this compound involves multiple steps, such as raw material acquisition, reaction conditions control and purification steps, which all affect the cost. If raw materials are scarce or the preparation process is complicated, the cost will be high, which will then push up the market price.
Furthermore, the relationship between market supply and demand is the key factor. If at some point, the chemical and pharmaceutical industries have a large increase in demand for this product, but the supply is limited, the price is bound to rise; conversely, if the demand is weak and the supply is sufficient, the price may decline.
In addition, differences in manufacturers also have an impact. Different manufacturers have different technical levels, production scales and management efficiencies, and costs and pricing will vary. Large-scale manufacturers may reduce costs and make prices more competitive due to scale effects.
In addition, the market environment should not be underestimated. Macroeconomic conditions, policies and regulations, and international trade conditions can all indirectly affect their prices. If the import of raw materials is blocked due to trade friction, or environmental protection policies increase production costs, price fluctuations may be triggered.
Due to the lack of specific market data and the dynamic changes of the above factors, it is difficult to determine the market price of 2-bromo-5-iodo-3-methylpyridine. For more information, please consult chemical product suppliers, trading platforms or related industry personnel to obtain more accurate price information.