As a leading (2-Butyl-1-Benzofuran-3-Yl)(4-Hydroxy-3,5-Diiodophenyl)Methanone supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
(2-butyl-1-benzofuran-3-yl) What are the chemical properties of (4-hydroxy-3,5-diiodophenyl) methanone?
(2-Butyl-1-benzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) methanone, an organic compound. Its chemical properties are unique, let me explain in detail.
From the structural point of view, the compound contains the structural fragments of benzofuran and diiodophenol. The aromatic structure of benzofuran endows it with certain stability and conjugation properties. The conjugation system can affect the electron cloud distribution of the molecule, which in turn has a significant effect on its spectral properties and chemical reactivity.
In terms of physical properties, due to the presence of polar carbonyl groups (methyl ketone groups) and hydroxyl groups in the molecule, it has a certain polarity and may have appropriate solubility in common organic solvents. However, the presence of long-chain butyl in the molecule will affect its solubility and melting point. Long-chain alkyl groups can increase the hydrophobicity of the molecule, or cause it to be poorly soluble in water, but better in some non-polar organic solvents.
When it comes to chemical activity, carbonyl is an activity check point. The carbon atom of the carbonyl group is partially positively charged and susceptible to attack by nucleophiles. It can undergo nucleophilic addition reactions, such as reacting with alcohols to form ketals, or reacting with Grignard reagents to form carbon-carbon bonds.
Hydroxy is also an important active site. Its hydrogen atom has a certain acidity, which can participate in acid-base reactions and form corresponding salts with bases. At the same time, the hydroxyl group can be used as a nucleophilic reagent to participate in esterification reactions and react with acyl halides or acid anhydrides to form ester compounds.
Furthermore, although the iodine atom on the benzene ring is relatively stable, under certain conditions, such as strong reducing agents or nucleophiles, iodine atom substitution reactions may occur, introducing new functional groups to the molecule and expanding the possibility of its chemical derivation.
Due to its unique structure and diverse chemical properties, this compound may have potential application value in organic synthesis, medicinal chemistry and other fields.
What are the common uses of (2-butyl-1-benzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) methanone?
(2-Butyl-1-benzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) methanone, an organic compound. Its common use is related to the field of medicinal chemistry.
In drug development, this compound may have unique pharmacological activity. Or as a potential lead compound, its structure has been carefully crafted by chemists to enhance its affinity and selectivity for specific disease-related targets. For example, for some inflammatory diseases, researchers may explore the possibility of inhibiting the inflammatory response by studying its interaction with key proteins in the inflammatory signaling pathway, just like building a bridge to precisely regulate inflammation in the microscopic world.
In the art of organic synthesis, it can serve as a key intermediate. Chemists use it as a cornerstone and follow ingenious reaction strategies to carefully splice other functional groups or structural fragments to build more complex and unique organic molecular architectures, just like skilled craftsmen build magnificent buildings with exquisite components.
In the field of materials science, it has emerged in the creation of specific functional materials due to the electronic properties and optical properties endowed by its special molecular structure. For example, in the exploration of optoelectronic device materials, it may participate in the construction of new organic semiconductor materials, paving a unique path for electron transition and charge transport, and helping to improve the performance of optoelectronic devices.
(2-butyl-1-benzofuran-3-yl) What are the synthesis methods of (4-hydroxy-3,5-diiodophenyl) methanone?
The synthesis of (2-butyl-1-benzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) methanone is a key field of organic synthetic chemistry. The synthesis route is often designed according to the organic reaction mechanism and existing chemical synthesis technology.
Under the paradigm of Tiangong Kaiji, the synthesis of this compound can be made from the selection of raw materials and the planning of reaction steps. The selection of raw materials should be pure and easy to obtain, such as benzofuran derivatives with specific substituents and iodophenol derivatives as starting materials. These two are more readily available in the organic chemical reagent market.
In terms of reaction steps, the benzofuran derivative can be reacted with an acylation reagent by Fu-Ke acylation reaction to introduce an acyl group at a specific position of the benzofuran. This step requires careful selection of reaction conditions, such as suitable catalysts, anhydrous aluminum trichloride is often preferred because it can effectively promote the reaction. Controlling the reaction temperature and time is also critical. Generally speaking, starting at a low temperature and gradually rising to a suitable reaction temperature can prevent side reactions from occurring.
Subsequently, the iodization reaction of the benzofuran intermediate containing the acyl group is carried out. Since the target product needs to introduce iodine atoms at the phenolic hydroxyl ortho-position, suitable iodine substitution reagents, such as iodine element and oxidant combination, can be selected to accurately realize the diiodine substitution reaction. During the reaction process, the choice of solvent is crucial, which should be able to dissolve the reactants without interfering with the reaction process. Common organic solvents such as dichloromethane, N, N-dimethylformamide, etc. can be considered.
The synthesis process also requires close monitoring of the reaction process. TLC, NMR and other analytical methods are used to ensure that each step of the reaction achieves the expected transformation, and subsequent reaction conditions are adjusted in time to obtain the target product (2-butyl-1-benzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) methanone.
(2-butyl-1-benzofuran-3-yl) In what fields is (4-hydroxy-3,5-diiodophenyl) methanone used?
(2-Butyl-1-benzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) methanone is used in many fields such as medicine and chemical industry.
In the field of medicine, it shows unique potential. Or it can be used as a lead compound through structural modification and optimization to develop new drugs. Due to the structure of benzofuran and diiodophenyl, it has specific biological activities, or has anti-inflammatory, anti-tumor, anti-viral and other effects. For example, it may play a regulatory role in some inflammation-related signaling pathways, thereby alleviating the inflammatory response; it may affect the proliferation and apoptosis of tumor cells, providing new ideas for the development of anti-tumor drugs.
In the chemical industry, it can be used as an intermediate in organic synthesis. By virtue of its own structural characteristics, it participates in a variety of organic reactions to build more complex organic compounds. For example, under specific conditions, it reacts with other compounds containing active groups to generate materials with special properties, which are used in coatings, plastics and other industries to improve the properties of materials, such as enhancing the corrosion resistance of coatings and the stability of plastics.
Furthermore, in materials science research, or because of its special molecular structure and physicochemical properties, its application in the preparation of new materials can be explored, contributing to the development of materials science.
(2-butyl-1-benzofuran-3-yl) What is the safety of (4-hydroxy-3,5-diiodophenyl) methanone?
(2-Butyl-1-benzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) methyl ketone, which is a chemical substance. Its safety is related to many aspects, let me elaborate.
First, in terms of toxicity, due to the presence of iodine atoms, there may be potential toxicity. Although iodine is an essential element for the human body, high concentrations of iodine in organic compounds may have adverse effects on the human body. Oral ingestion, or irritation of the digestive system, can cause nausea, vomiting, abdominal pain, etc.; long-term exposure to large amounts, or damage the liver and kidney function, interfering with the normal metabolism of the human body.
Secondly, the environmental impact is discussed. If the substance enters the environment, it may be difficult to degrade naturally due to its complex structure. Residual in the soil, or affect the activity and fertility of soil microorganisms; enter the water body, or endanger aquatic organisms. Its chemical structure characteristics, or enrich organisms in the food chain, pose a threat to advanced organisms through transmission.
Furthermore, it is related to the risk of ignition and explosion. Although there are no obvious flammable groups, it may encounter hot topics, open flames or strong oxidants, or cause chemical reactions, which may burn or even explode. During storage and use, improper handling, such as mixing with incompatible substances, may also trigger dangerous reactions.
When using this chemical, be sure to strictly follow safety procedures. Operators should wear protective clothing, protective gloves and goggles to prevent skin-eye contact. Operate in a well-ventilated manner to avoid inhalation of steam or dust. When storing, it should be placed in a cool, dry and ventilated place, away from fires, heat sources and oxidants. In this way, the use process is safe and the harm to human body and the environment is reduced.