2-butyl-3-benzofuranyl 4-hydroxy-3,5-diiodophenyl Ketone

2-butyl-3-benzofuranyl 4-hydroxy-3,5-diiodophenyl Ketone, let me describe it. This compound can be derived from its name and its elements.
The "2-butyl-3-benzofuranyl" part can be made of benzofuranyl, which is a benzofuranyl fused with benzofuranyl. In the third position of benzofuranyl, it is connected to a butyl (butyl) group, and the butyl group contains a straight alkyl group with four carbon atoms, that is, -CH -2 CH -2 CH ³ CH.
This part of "4-hydroxy-3,5-diiodophenyl" is a phenyl group (phenyl), which has a hydroxy (-OH) at the 4th position, and an iodo atom (iodo, that is, -I) at the 3rd and 5th positions.
And "Ketone" indicates that this compound is a ketone, that is, the above-mentioned phenyl group containing a phenyl group and an iodine atom, and a permeable carbonyl (C = O) phase. Therefore, 2-butyl-3-benzofuranyl 4-hydroxy-3,5-diiodophenyl Ketone is composed of a butyl-containing benzofuranyl group, a phenyl group containing a butyl group and an iodine atom, and a carbonyl group.

2 - butyl - 3 - benzofuranyl + 4 - hydroxy - 3,5 - diiodophenyl Ketone, Chinese name or 2 - butyl - 3 - benzofuranyl - 4 - hydroxy - 3,5 - diiodophenyl ketone. This compound has a wide range of uses in the fields of medicine and chemical industry.
In the process of pharmaceutical research and development, it is often a key intermediate for the creation of new drugs. Due to its unique chemical structure and activity, it can target specific disease-related targets. For example, it may be possible to modify the structure of this compound to enhance its affinity with certain receptors, and then develop specific drugs for specific diseases (such as tumors and nervous system diseases). According to the method of drug research and development contained in ancient books, "observe its physical properties, adjust its compatibility, so as to achieve the effect of treating diseases". The development of new drugs in this compound also follows this path, observe its chemical activity, adjust its structure, and hope to achieve the effect of curing diseases and saving people.
In the chemical industry, it can be used as a synthetic raw material for special functional materials. Its structure gives the material unique physical and chemical properties, such as in optical materials, or it can change the light absorption and emission characteristics of the material to make a material with special optical properties, which is used in optical instruments, display technology and other fields. In the field of chemical materials, this compound can play a unique role because of its unique structure.
And because of its special atoms such as iodine, it can also show unique advantages in the stability and antibacterial properties of materials, and can be used to develop antibacterial materials. For example, ancient man-made materials pay attention to making the best use of things. The characteristics of this compound can also be fully played in the development of materials and contribute to the development of chemical materials.

The preparation of 2 - butyl - 3 - benzofuranyl + 4 - hydroxy - 3,5 - diiodophenyl Ketone is particularly complicated and requires fine organic synthesis.
First of all, appropriate starting materials need to be prepared. To obtain this compound, benzofuran derivatives with specific substituents and benzene derivatives containing hydroxyl and iodine substituents can be selected as starting materials. If suitable 2 - butyl benzofuran is selected, and its 3 - position reserved reaction check point, and 4 - hydroxy - 3,5 - diiodobenzene, as the key starting materials.
The second step is the reaction step. The two can be formed into ketones through the Friedel-Crafts acylation reaction. In the reaction system, a suitable Lewis acid catalyst, such as anhydrous aluminum trichloride (AlCl
), is added, which can activate the benzene ring and promote the electrophilic substitution reaction. The starting material is dissolved in a suitable aprotic solvent, such as dichloromethane (CH < Cl < 2), and the reactant is slowly added dropwise at low temperature to ensure a smooth reaction. The reaction process needs to be in an inert gas protective atmosphere, such as nitrogen (N < 2), to prevent the oxidation of the raw material and the product.
After the reaction is completed, a post-treatment step is required. The reaction mixture is quenched with ice water to stop the reaction. After that, the product is extracted with an organic solvent, such as ether extraction. The organic phases are combined and washed in sequence with an appropriate amount of dilute acid, dilute alkali and water to remove impurities and unreacted raw materials. The organic phase is dried with anhydrous sodium sulfate (Na ² SO), filtered and then evaporated to remove the solvent to obtain a crude product.
The end is the product purification. The crude product needs to be purified by column chromatography, with silica gel as the fixed phase and an appropriate proportion of petroleum ether and ethyl acetate mixture as the mobile phase. The purpose of separation and purification is based on the difference in the partition coefficient between the product and the impurities between the fixed phase and the mobile phase. Through these steps, pure 2 - butyl - 3 - benzofuranyl + 4 - hydroxy - 3,5 - diiodophenyl Ketone can be obtained.

2-Butyl-3-benzofuranyl-4-hydroxy-3,5-diiodophenyl ketone, which is an organic compound. It has specific physical and chemical properties.
Looking at its physical properties, under normal conditions, or as a solid state, it also depends on the surrounding environmental conditions. The values of melting point and boiling point are crucial to distinguish its physical state at different temperatures. Although accurate data are not available, it can be inferred that the melting point is within a certain range due to the bonding mode and interaction between atoms in the molecule. For example, there are hydrogen bonds between molecules, van der Waals forces, etc., or the melting point is increased.
As for solubility, its performance in organic solvents may be different from that in water. Because the compound has hydrophobic groups such as benzofuran and phenyl, its solubility may be limited in polar organic solvents such as ethanol and acetone; while in non-polar organic solvents such as toluene and dichloromethane, its solubility may be better. This property is closely related to the polarity of the molecule, and the non-polar part makes it tend to be miscible with non-polar solvents.
In terms of chemical properties, the hydroxyl groups in the molecule are quite active. Hydroxyl groups can participate in many chemical reactions, such as esterification reactions, which react with acids to form ester compounds; they can also undergo oxidation reactions to convert into aldehyde groups or carboxyl groups. Furthermore, the presence of benzofuran rings and phenyl groups enables the compound to undergo aromatic electrophilic substitution reactions. Due to the electron-rich properties of the benzene ring, it is vulnerable to attack by electrophilic reagents, such as halogenation, nitrification, sulfonation and other reactions may occur. And although the iodine atom of the diiodophenyl part is relatively stable, under specific conditions, it may participate in the substitution reaction and be replaced by other groups, and then derive a variety of compounds. In short, this compound exhibits rich physical and chemical properties due to its unique structure, and may have potential application value in organic synthesis and other fields.

2 - butyl - 3 - benzofuranyl 4 - hydroxy - 3,5 - diiodophenyl Ketone is an organic compound, and there are many points to be paid attention to during use.
The first thing to pay attention to is its toxicity and safety. The chemical structure of this compound is complex, and some structural units may be potentially toxic. When using, be sure to strictly follow safety procedures, operate in a well-ventilated environment, and wear protective equipment such as gloves, goggles, and gas masks to prevent skin contact, inhalation, or ingestion, which may cause damage to human health, such as irritation to the skin, eyes, and even affect the respiratory system and nervous system.
Furthermore, pay attention to its stability and storage conditions. In view of its iodine atoms, etc., or sensitive to light and heat. It should be stored in a cool, dry and dark place, away from fire sources and oxidants, to avoid chemical reactions that cause deterioration or danger. After taking it, it must be properly sealed to prevent contact with air, moisture, etc.
In addition, the chemical reaction conditions during use cannot be ignored. The reactions it participates in may require harsh conditions such as temperature, pH, and reaction time. Too high or too low temperature may affect the reaction rate and product purity; inappropriate pH or reaction cannot be carried out, or by-products are formed. Therefore, it is necessary to precisely control the reaction conditions and explore the best parameters with the help of experimental means.
At the same time, the treatment of its reaction products and waste should also be cautious. Reaction products need to be properly separated and purified according to their characteristics to achieve the desired purity. Waste should not be discarded at will, because it may be toxic or environmentally hazardous, it needs to be specially treated in accordance with relevant environmental regulations to reduce the impact on the environment.
In short, when using 2-butyl-3-benzofuranyl 4-hydroxy-3,5-diiodophenyl Ketone, care needs to be taken from safety protection, storage conditions to reaction control and waste treatment to ensure that the use process is safe, effective and environmentally friendly.