2 Chloro 1 Iodo 4 Methylbenzene
Iodobenzene

2 Chloro 1 Iodo 4 Methylbenzene

Fengxi Chemical

Specifications

HS Code

747397

Chemical Formula C7H6ClI
Molar Mass 254.48 g/mol
Appearance A colorless to light yellow liquid
Boiling Point Approximately 237 - 239 °C
Density Around 1.85 - 1.95 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether, and chloroform
Flash Point Relatively high, as it is an aromatic halide
Odor Characteristic aromatic and halogen - like odor
Chemical Formula C7H6ClI
Molar Mass 254.48 g/mol
Appearance Liquid (usually)
Odor Characteristic aromatic odor
Density Approx. 1.8 - 2.0 g/cm³ (estimated)
Boiling Point Approx. 210 - 230 °C (estimated)
Melting Point Low melting point (approx. below 0 °C, estimated)
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point Relatively high (estimated > 100 °C)
Chemical Formula C7H6ClI
Molar Mass 254.48 g/mol
Appearance Liquid (expected, based on similar compounds)
Solubility In Water Low (organic halide, non - polar)
Solubility In Organic Solvents Soluble (e.g., in ethanol, ether)
Odor Pungent (expected for aromatic halide)
Reactivity Reactive towards nucleophiles due to halogen atoms
Packing & Storage
Packing 500g of 2 - chloro - 1 - iodo - 4 - methylbenzene packaged in a sealed glass bottle.
Storage 2 - Chloro - 1 - iodo - 4 - methylbenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be stored in a tightly - sealed container made of materials resistant to corrosion, like glass or some high - density plastics. Keep it separate from oxidizing agents and reactive chemicals to prevent potential chemical reactions.
Shipping 2 - chloro - 1 - iodo - 4 - methylbenzene is shipped in sealed, corrosion - resistant containers. It must be labeled as a hazardous chemical. Shipment is arranged following strict regulations to ensure safe transport.
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2-chloro-1-iodo-4-methylbenzene 2-chloro-1-iodo-4-methylbenzene 2-chloro-1-iodo-4-methylbenzene
General Information
Frequently Asked Questions
What is the chemistry of 2-chloro-1-iodo-4-methylbenzene?
2-Chloro-1-iodine-4-methylbenzene is also an organic compound. Its chemical properties depend on the functional groups it contains and the characteristics of the benzene ring.
Chlorine atoms and iodine atoms on the benzene ring are both halogen atoms. Halogen atoms have electron-absorbing induction effect, which can reduce the electron cloud density of benzene ring, which in turn affects the reactivity of this compound. In terms of electrophilic substitution reaction, although halogen atoms are adjacent and para-localized groups, their electrophilic substitution activity of benzene ring is lower than that of benzene due to their electron-absorbing induction effect.
methyl is attached to the benzene ring, which has a push electron induction effect, which can increase the electron cloud density of the benzene ring in the ortho and para-positions, which also affects the position selectivity of the electrophilic substitution reaction. Among many reactions, the push electron property of methyl makes the reaction more likely to occur in the ortho and para-positions of methyl.
The halogen atom in this compound can participate in the nucleophilic substitution reaction. The chlorine atom and the iodine atom have different reactivity due to the difference in atomic radius and electronegativity. The iodine atom has a large radius and the C-I bond energy is relatively small. In the nucleophilic substitution reaction, the iodine atom is more likely to leave and the < Br >
In the oxidation reaction, the methyl group of the side chain of the benzene ring can be oxidized under appropriate conditions. For example, when treated with a strong oxidizing agent, the methyl group can be gradually oxidized to a carboxyl group.
And because it is a halogenated aromatic hydrocarbon, it undergoes degradation reactions in the environment or due to the action of microorganisms. However, the presence of halogen atoms may make the degradation process more complicated than that of general aromatics.
In short, the chemical properties of 2-chloro-1-iodine-4-methylbenzene are formed by the interaction of its benzene ring, halogen atom and methyl group, and show unique reaction characteristics in various organic reactions.
What are the physical properties of 2-chloro-1-iodo-4-methylbenzene?
2-Chloro-1-iodine-4-methylbenzene is one of the organic compounds. Its physical properties are quite characteristic, and this is for you to describe in detail.
Looking at its morphology, under room temperature and pressure, 2-chloro-1-iodine-4-methylbenzene is often in a liquid state, with a relatively uniform texture and acceptable fluidity.
As for the color, this compound is mostly colorless to light yellow, like a clear liquid, slightly transparent to light yellow, and the appearance is quite clear.
Smell its smell, which has a certain volatility and emits a unique aromatic smell. However, this smell is not rich and pungent, but has a specific organic smell.
When it comes to density, its density is larger than that of water. If it is placed in one place with water, it can be seen that it sinks to the bottom of the water, like a pearl falling into the abyss. This characteristic is due to the quality characteristics given by its molecular structure and composition.
Solubility is also an important physical property. 2-Chloro-1-iodine-4-methylbenzene is insoluble in water, because water is a polar solvent, and the molecular polarity of this compound is relatively weak. According to the principle of "similar miscibility", the two are difficult to miscible. However, in organic solvents, such as ethanol, ether, chloroform, etc., its solubility is quite good, and it can be miscible with it, just like water emulsion blending to form a uniform solution.
The boiling point of 2-chloro-1-iodine-4-methylbenzene is moderate due to intermolecular forces. Under specific pressure conditions, it needs to be given a certain amount of heat to make it boil into a gaseous state. The value of this boiling point is closely related to the bond energy between atoms in the molecule and the interaction between molecules.
The melting point is also a consideration point. Its melting point is within a certain range. At this temperature, the compound is in a solid state, and above this temperature, it gradually melts into a liquid state. The melting point is also determined by the regularity of the molecular structure and the interaction force.
The above is the main physical property of 2-chloro-1-iodine-4-methylbenzene. Its unique properties are of great significance in the field of organic chemistry, whether it is research and exploration or practical application.
What are the main uses of 2-chloro-1-iodo-4-methylbenzene?
2-Chloro-1-iodine-4-methylbenzene, this substance is widely used in the field of chemical industry.
First, it is often used as a key intermediate in the process of organic synthesis. Chlorine, iodine and methyl groups attached to the benzene ring have unique reactivity. Chlorine atoms and iodine atoms can introduce multiple functional groups to the benzene ring through nucleophilic substitution reactions. For example, when interacting with nucleophiles such as alkoxides and amines, ether and amine derivatives can be formed, thereby expanding the structural complexity of organic molecules and laying the foundation for the creation of various organic compounds.
Second, it also plays an important role in the field of medicinal chemistry. The construction of many drug molecules is based on this as the starting material. By modifying and transforming the functional groups on its benzene ring, the physicochemical properties and biological activities of the molecule can be adjusted. Or change its fat solubility, water solubility, or affect the ability to bind to biological targets, and then develop drugs with better curative effect and less side effects.
Third, in the field of materials science, 2-chloro-1-iodine-4-methylbenzene may be able to participate in the synthesis of high-performance materials. For example, when synthesizing special polymers, they can participate in the polymerization reaction as monomers, giving the polymers special electrical, optical or mechanical properties to meet the special needs of materials in fields such as electronic devices and optical materials.
In conclusion, although 2-chloro-1-iodine-4-methylbenzene is one of the organic compounds, it has shown value that cannot be ignored in many important fields such as organic synthesis, drug research and development, and material preparation, promoting the progress and development of technologies in various fields.
What are 2-chloro-1-iodo-4-methylbenzene synthesis methods?
There are several common methods for synthesizing 2-chloro-1-iodine-4-methylbenzene.
First, p-methylchlorobenzene is used as the starting material. Iodine atoms are introduced into p-methylchlorobenzene through halogenation reaction. In this halogenation reaction, suitable halogenating reagents are often required. For example, iodine element can be replaced by iodine atom at a specific position in the benzene ring under the action of a specific catalyst. This process requires fine regulation of reaction conditions, such as reaction temperature and catalyst dosage. If the temperature is too high, it is easy to cause side reactions to occur and form polyhalogenated products; if the temperature is too low, the reaction rate is slow and the yield is affected.
Second, using p-methyl iodobenzene as the starting material, chlorine atoms are introduced through chlorination reaction. In the chlorination reaction, chlorine gas or other chlorinated reagents are commonly used. However, this reaction also needs to be carefully controlled. Due to the high reactivity of benzene ring, if the conditions are improper, it is easy to form a variety of chlorinated isomers. Therefore, the reaction conditions, such as solvent type and reaction time, need to be precisely selected, so that the chlorine atoms can be selectively replaced to the target position.
Third, 4-methylaniline can also be started. First, the amino group is converted into a diazonium salt by diazotization reaction, and then reacted with iodine-containing and chlorine-containing reagents respectively, and then iodine atoms and chlorine atoms The diazotization reaction needs to be carried out in a low temperature environment to ensure the stability of the diazonium salt. Subsequent reactions with halogenated reagents also need to strictly control the conditions to obtain high-purity 2-chloro-1-iodine-4-methylbenzene.
Synthesis of this compound requires weighing the advantages and disadvantages of each method according to the actual situation, and precisely controlling the reaction conditions to achieve the ideal yield and purity.
2-chloro-1-iodo-4-methylbenzene What are the precautions during storage and transportation?
2-Chloro-1-iodine-4-methylbenzene is also an organic compound. During storage and transportation, many matters must be paid attention to.
First words storage. This compound has a certain chemical activity and should be stored in a cool, dry and well-ventilated place. Because heat can easily exacerbate chemical reactions and cause danger, it is essential to avoid high temperature environments. And it is quite sensitive to moisture, moisture intrusion or deterioration, so it is important to keep the storage environment dry. In addition, it must be separated from chemicals such as oxidants and strong bases, because it is easy to react violently with them, endangering safety.
Second talk about transportation. During transportation, it is necessary to ensure that the container is well sealed to prevent leakage. This compound may be harmful to the human body and the environment. If it leaks, it will be difficult to clean up and dispose of it. The means of transportation also need to be adapted to have good heat insulation and shock resistance. In order to prevent the package from being damaged due to temperature fluctuations and vibration. At the same time, transporters should be familiar with the characteristics of this compound and emergency treatment methods. In case of emergencies, they can respond quickly to reduce the damage.
Furthermore, whether it is storage or transportation, relevant places and tools should be affixed with prominent warning signs, indicating its chemical hazards, so that relevant personnel should be vigilant and operate cautiously. All of these are to ensure the safety of 2-chloro-1-iodine-4-methylbenzene during storage and transportation and should not be ignored.