What is the main use of (2 -chloro-5 -iodophenyl) [4- [[ (3s) -tetrahydro- 3 -furanyl] oxy] phenyl] methanone
(2-Tritium-5-pyrimidinyl) [4- [ (3s) -tetrahydro-3-furyl] oxy] pyrimidinyl] ethyl ether, its main use is for the key raw materials of pharmaceutical synthesis.
According to Guan Fu's "Tiangongkai", all things in the world have their uses, and this (2-tritium-5-pyrimidinyl) [4- [[ (3s) -tetrahydro-3-furyl] oxy] pyrimidinyl] ethyl ether is no exception. In the field of medicine, it is often the starting material for the synthesis of specific drugs. Due to its unique chemical structure, it can undergo many chemical reactions and skillfully combine with other compounds to construct drug molecules with specific pharmacological activities.
When synthesizing some antiviral drugs, this ethyl ether can be used as a key structural fragment to participate in the construction of drug molecules, so that the obtained drugs can accurately act on specific targets of viruses, hindering the replication and transmission of viruses, and achieving the effect of treating viral infections. For example, in the development of anti-tumor drugs, chemical modification and modification based on it may be able to create new drugs with highly selective killing effects on tumor cells, bringing good news to tumor patients. The
cover has attracted the attention and attention of medical researchers because it plays such an important role in pharmaceutical synthesis, and it is an indispensable and important substance in the field of medicine.
What are the physical properties of (2-chloro-5-iodophenyl) [4- [[ (3s) -tetrahydro-3-furanyl] oxy] phenyl] methanone
(Di-cyano-5-pyrimidinyl) [4- [ (3s) -tetrahydro-3-furanyl] oxy] phenyl] carbamate ethyl ester is a white to off-white crystalline powder. It has a certain melting point and can be dissolved in suitable solvents. Physical properties such as density are similar to general organic compounds, insoluble in water, and easily soluble in common organic solvents such as dichloromethane, N, N-dimethylformamide, etc.
This substance is relatively stable at room temperature and pressure, but care should be taken to avoid contact with strong oxidants, strong acids, strong bases and other substances to prevent chemical reactions. Its appearance is powdery, making it easy to store and transport, but it needs to be sealed to prevent moisture and reaction with air components. Under certain conditions, crystal form transformation may occur, affecting its related properties, so storage conditions are quite critical. It is generally recommended to store in a cool, dry place.
What are the chemical properties of (2-chloro-5-iodophenyl) [4- [ (3s) -tetrahydro-3-furanyl] oxy] phenyl] methanone
(2-Cyano-5-pyrimidinyl) [4- [ (3s) -tetrahydro-3-furanyl] oxy] phenyl] acetic acid is an organic compound with unique chemical properties.
Among this compound, the cyanyl group has high activity. Cyanyl contains carbon-nitrogen triple bonds, has strong electron-absorbing properties, and can cause changes in the density distribution of molecular electron clouds. It is easy to participate in nucleophilic substitution reactions. In case of nucleophiles, one of the carbon-nitrogen triple bonds may be broken, and the nucleophilic reagent is connected to the carbon atom and substituted. Under suitable conditions, cyanyl groups can be hydrolyzed and converted into carboxyl groups, which is commonly used in organic synthesis to prepare carboxyl-containing compounds.
Pyrimidine groups also affect the properties of compounds. Pyrimidine is a nitrogen-containing heterocycle, which has aromatic properties and can enhance molecular stability. Pyrimidine cyclic nitrogen atoms can act as hydrogen bond receptors and form hydrogen bonds with hydrogen-containing donor molecules, which is of great significance in molecular recognition and supramolecular assembly.
Looking at the [4- [[ (3s) -tetrahydro-3-furanyl] oxy] phenyl] part, the phenyl ring is rich in electrons, prone to electrophilic substitution reactions, and electrophilic reagents are prone to attack the phenyl ring, and new groups are introduced into the phenyl ring. As a cyclic ether structure, tetrahydrofuran group has certain stability, and oxygen atoms can participate in coordination or form hydrogen bonds, which affects the solubility and intermolecular forces of compounds.
As for the acetic acid part, the carboxyl group is acidic, which can ionize hydrogen ions and react with bases to form salts. At the same time, carboxyl groups can participate in esterification reactions, and alcohol can form ester compounds under the action of catalysts. In general, (2-cyano-5-pyrimidinyl) [4- [ (3s) -tetrahydro-3-furanyl] oxy] phenyl] acetic acid exhibits rich chemical properties due to the interaction of various functional groups, and may have important applications and research values in organic synthesis, medicinal chemistry and other fields.
What is the synthesis method of (2-chloro-5-iodophenyl) [4- [[ (3s) -tetrahydro-3-furyl] oxy] phenyl] methanone
The synthesis method of (2-ammonia-5-bromopyridine) [4- [ (3s) -tetrahydro-3-morpholinyl] amino] pyridine] pyridine ethyl ester is as follows:
First, with suitable starting materials, the target product is obtained by delicate multi-step transformation.
First take (2-ammonia-5-bromopyridine), which is one of the key starting materials. Find suitable reaction conditions to interact with appropriate reagents. For example, nucleophilic substitution reactions can occur with a compound containing a specific functional group in a suitable solvent at a certain temperature and catalyzed by a catalyst. This reaction requires precise control of reaction temperature, time and reactant ratio to ensure that the reaction proceeds in the expected direction and generates preliminary intermediates.
For [4- [ (3s) -tetrahydro-3-morpholinyl] amino] pyridine] fractions, a series of reactions are also required to construct. The (3s) -tetrahydro-3-morpholinyl related intermediates can be prepared first, starting with suitable nitrogen-containing heterocyclic compounds, through reduction, substitution and other reactions, the desired substituents are introduced to form the (3s) -tetrahydro-3-morpholinyl structure, and then it reacts with pyridine derivatives to connect to pyridine rings to generate corresponding pyridine derivative intermediates.
Finally, the two key intermediates obtained above are connected to form the final (2-ammonia-5-bromopyridine) [4- [[ (3s) -tetrahydro-3-morpholinyl] amino] pyridine] pyridine ethyl ester product under specific conditions through condensation reactions. In this process, factors such as the choice of solvent, the amount of base, reaction temperature and time all have an important impact on the reaction yield and product purity. It is necessary to fine-tune each reaction parameter, separate and purify to obtain a high-purity target product. The entire synthesis route requires careful design and control by chemists to achieve efficient and accurate synthesis.
What is the price range of (2-chloro-5-iodophenyl) [4- [[ (3s) -tetrahydro-3-furanyl] oxy] phenyl] methanone in the market
What is the price range of (di-neon-five-benzyl) [tetra- [ (3s) -tetrahydro-tri-morpholinyl] oxy] benzyl] acetic acid above the market?
I try to solve this question by using the method of ancient Chinese saying. In this world, the price of things often varies according to many reasons. The range of the price of this (di-neon-five-benzyl) [tetra- [[ (3s) -tetrahydro-tri-morpholinyl] oxy] benzyl] acetic acid is difficult to determine.
First, the production of this product, if the labor and materials consumed are huge, the price will be high. The thinness of the raw materials and the difficulty of preparation are all related to its essence. If the use of neon, or the need for delicate techniques, if benzyl and other raw materials are rare, their value will increase.
Second, the supply and demand of the city is also the main reason. If this product is needed by the public, the price will rise; on the contrary, if the supply exceeds the demand, the price may drop.
Third, the rules of the market, the distance of the land, and the circulation of time also have an impact. In Dayi, the capital of Tongdu, merchants converge, competition or drama, the price or leveling; in remote places, the transfer of goods is not easy, and the price may increase. With time shifting, prices may also rise and fall.
With common sense, if the preparation of this product is not extremely difficult, and the supply and demand of the city are slightly even, its price may be at a moderate level; if the raw materials are rare, the preparation is complicated, and there are many people who need it, the price may be high. However, it is difficult to determine the range of its price. It is necessary to carefully examine the actual situation of the city and the section of the production system before we can obtain a more accurate number.