2 Chloro 5 Iodophenyl 4 Ethoxyphenyl Methanone
Iodobenzene

(2-chloro-5-iodophenyl)(4-ethoxyphenyl)methanone

Fengxi Chemical

Specifications

HS Code

418165

Chemical Formula C15H12ClIO2
Molar Mass 388.61 g/mol
Appearance Solid (predicted, based on similar aromatic ketones)
Solubility In Water Low (due to non - polar aromatic rings)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (due to non - polar nature)
Chemical Formula C15H12ClIO2
Molecular Weight 388.61
Appearance Solid (predicted)
Melting Point N/A (no data found)
Boiling Point N/A (no data found)
Density N/A (no data found)
Solubility In Water Insoluble (predicted)
Solubility In Organic Solvents Soluble in common organic solvents (predicted)
Flash Point N/A (no data found)
Purity N/A (no specific purity given)
Chemical Formula C15H12ClIO2
Molecular Weight 388.61
Appearance Solid (predicted)
Boiling Point Estimated around 433.6°C at 760 mmHg
Density Estimated around 1.666 g/cm³
Solubility Poorly soluble in water, may be soluble in organic solvents like dichloromethane, chloroform
Logp Estimated to be relatively high, indicating lipophilicity
Pka No acidic or basic functional groups likely to have significant pKa values in common pH range
Vapor Pressure Very low vapor pressure (solid compound)
Chemical Formula C15H12ClIO2
Molar Mass 388.61 g/mol
Appearance Solid (predicted, exact depends on purity and conditions)
Solubility Expected to be sparingly soluble in water, more soluble in organic solvents like dichloromethane, chloroform etc. due to its non - polar nature
Packing & Storage
Packing 100g of (2 - chloro - 5 - iodophenyl)(4 - ethoxyphenyl)methanone in sealed chemical - grade container.
Storage (2 - chloro - 5 - iodophenyl)(4 - ethoxyphenyl)methanone should be stored in a cool, dry place away from direct sunlight. Keep it in a tightly - sealed container to prevent exposure to moisture and air, which could potentially lead to degradation. Store it separately from incompatible substances, like strong oxidizing agents or reducing agents, to ensure safety and chemical stability.
Shipping (2-chloro-5-iodophenyl)(4-ethoxyphenyl)methanone will be shipped in accordance with strict chemical transport regulations. Packed securely in appropriate containers, it will be dispatched via a reliable carrier ensuring safe and timely delivery.
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(2-chloro-5-iodophenyl)(4-ethoxyphenyl)methanone (2-chloro-5-iodophenyl)(4-ethoxyphenyl)methanone (2-chloro-5-iodophenyl)(4-ethoxyphenyl)methanone
General Information
Frequently Asked Questions
What is the chemical structure of (2-chloro-5-iodophenyl) (4-ethoxyphenyl) methanone?
(2-Chloro-5-iodophenyl) (4-ethoxyphenyl) methanone, its chemical structure can be interpreted as follows:
This compound is a methyl ketone substance, and the methanone structure is a carbonyl group (\ (C = O\)). Two different aryl groups are connected on both sides.
One is (2-chloro-5-iodophenyl). The phenyl group is substituted with a chlorine atom (\ (Cl\)) at position 2 and an iodine atom (\ (I\)) at position 5. The benzene ring is composed of six carbon atoms, each carbon atom is connected to a hydrogen atom, except for the substituted position. The chlorine atom and the iodine atom replace the corresponding position hydrogen atom respectively.
The other is (4-ethoxyphenyl), which is connected to the ethoxy group at position 4 (\ (- OCH_ {2} CH_ {3}\)). In the ethoxy group, the oxygen atom (\ (O\)) is connected to the carbon at position 4 of the benzene ring, and the other side of the oxygen atom is connected to the ethyl group (\ (- CH_ {2} CH_ {3}\)). Ethyl consists of two carbon atoms and five hydrogen atoms, one of which is connected to the oxygen atom.
The two aryl groups are connected by the carbon atom of the carbonyl group to form the monolithic structure of (2-chloro-5-iodophenyl) (4-ethoxyphenyl) methanone. This structure endows the compound with specific physical and chemical properties and may have important uses in the fields of organic synthesis and medicinal chemistry.
What are the physical properties of (2-chloro-5-iodophenyl) (4-ethoxyphenyl) methanone?
(2-Chloro-5-iodophenyl) (4-ethoxyphenyl) methyl ketone is an organic compound. It has unique physical properties and is very important for chemical research and application.
Looking at its properties, under normal conditions, this compound is mostly crystalline solid with fine texture and a certain luster. Such appearance characteristics can be used as a preliminary basis for the identification and identification of compounds.
When it comes to melting point, (2-chloro-5-iodophenyl) (4-ethoxyphenyl) methyl ketone has a specific melting point range. Accurate determination of melting point is of great significance for purity determination. With high purity, the melting point is sharp and the fluctuation range is narrow; when impurities are contained, the melting point decreases and the melting range becomes wider.
Solubility is also a key physical property. The compound has different solubility in organic solvents. In common organic solvents such as dichloromethane and chloroform, it has good solubility and can be uniformly dispersed to form a solution. This property is crucial in organic synthesis and separation and purification steps, which is conducive to the reaction and product separation.
In water, (2-chloro-5-pheniodoyl) (4-ethoxyphenyl) methanone has poor solubility. Because its molecular structure contains hydrophobic groups, it has weak interaction with water molecules, so it is difficult to dissolve in water.
In addition, (2-chloro-5-iodophenyl) (4-ethoxyphenyl) methyl ketone has a certain density, and the density value has a significant impact on chemical production, storage and transportation, which is related to container selection and material quantity calculation.
In the study and application of (2-chloro-5-iodophenyl) methyl ketone, a comprehensive understanding of the above physical properties is of great significance for grasping its chemical behavior and realizing effective utilization.
(2-chloro-5-iodophenyl) What are the main synthesis methods of (4-ethoxyphenyl) methanone?
The main synthesis methods of (2-chloro-5-iodophenyl) (4-ethoxyphenyl) methyl ketone generally include the following.
First, the acylation method. Perform the Fu-gram acylation reaction with an appropriate aryl halide and an acyl halide or an acid anhydride in the presence of a Lewis acid such as aluminum trichloride in a catalyst. For example, 2-chloro-5-iodobenzene and 4-ethoxybenzoyl halide can be obtained by heating and stirring the reaction in a suitable solvent such as dichloromethane under the catalysis of aluminum trichloride. The mechanism of this reaction lies in the complexation of Lewis acid with the carbonyl oxygen of the acyl halide, which enhances the electrophilicity of the acyl halide, and then undergoes electrophilic substitution reaction with the aromatic ring.
Second, the coupling reaction catalyzed by transition metals. For example, by using the palladium-catalyzed cross-coupling reaction, 2-chloro-5-iodophenylboronic acid (or its derivatives) and 4-ethoxyhalobenzophenone as raw materials, under the action of base and palladium catalyst such as tetra (triphenylphosphine) palladium, etc., in suitable solvents such as toluene, dioxane, etc., heating reaction can obtain the target product. This reaction relies on the activation of the transition metal palladium to the halogen atom and boric acid group to realize the coupling of carbon-carbon bonds.
Third, phenolic compounds are used as starting materials. First, 4-ethoxy phenol is acylated to obtain the corresponding acetylation products. After the halogenation reaction, chlorine atoms and iodine atoms are introduced at suitable positions, and finally (2-chloro-5-iodophenyl) (4-ethoxy phenyl) methyl ketone. Suitable halogenating reagents can be selected for the halogenation reaction, such as N-chlorosuccinimide (NCS) for chlorination, iodine elemental substance and appropriate oxidant for iodine generation.
(2-chloro-5-iodophenyl) In what fields is (4-ethoxyphenyl) methanone used?
(2-Chloro-5-iodophenyl) (4-ethoxyphenyl) methanone, an organic compound. It has applications in many fields, and listen to me one by one.
In the field of medicinal chemistry, such compounds containing halogen atoms and ethoxy groups often exhibit unique biological activities. The presence of halogen atoms and ethoxy groups can significantly change the physical and chemical properties of compounds, such as lipophilicity, molecular polarity, etc., which in turn affect their interaction with targets in vivo. Scientists often use it as a lead compound, and through structural modification and optimization, they are dedicated to the development of new drugs, such as anti-cancer drugs, anti-infective drugs, etc.
In the field of materials science, this compound may have made a name for itself in the field of optoelectronic materials due to its special structure. Its molecular structure can endow materials with specific optoelectronic properties, such as fluorescence properties, charge transport capabilities, etc. Therefore, it may be used to prepare organic Light Emitting Diodes (OLEDs), solar cells and other optoelectronic devices to help improve device performance and efficiency.
Furthermore, in the field of organic synthesis chemistry, (2-chloro-5-iodophenyl) (4-ethoxyphenyl) methanone is an important intermediate. With the active reactivity of halogen atoms, more complex organic molecular structures can be constructed through a variety of organic reactions, such as coupling reactions, substitution reactions, etc., which lays the foundation for the synthesis of organic compounds with specific functions and structures.
In summary, (2-chloro-5-iodophenyl) (4-ethoxyphenyl) methyl ketone has non-negligible application value in many fields such as medicine, materials, and organic synthesis, providing an important material basis and research direction for the development of various fields.
(2-chloro-5-iodophenyl) What is the market outlook for (4-ethoxyphenyl) methanone?
(2-Chloro-5-iodophenyl) (4-ethoxyphenyl) methanone, the prospect of this substance in today's market situation is actually related to many aspects.
Looking at its chemical properties, the structure of methanone composed of 2-chloro-5-iodophenyl and 4-ethoxyphenyl gives it unique physical and chemical properties. In the field of organic synthesis, due to the existence of halogen atoms such as chlorine and iodine and ethoxy groups in its structure, it can be used as a key intermediate to participate in various chemical reactions. Therefore, in the fine chemical industry, it may occupy an important position in the synthesis path of medicine, pesticides, materials, etc.
Discussing the prospects in the field of medicine, the delicate combination of halogen atoms and ethoxy groups may give them specific biological activities. Halogen atoms can affect the lipophilicity of molecules and the distribution of electron clouds, while ethoxy groups may be able to adjust the interaction between molecules and biological targets. Therefore, it is expected to develop new drugs based on this, such as therapeutic drugs for specific diseases, which is a major addressable market direction.
The field of pesticides should not be underestimated. Its unique structure may have special inhibitory or killing effects on certain pests and pathogens. With the increasing demand for green and efficient pesticides, if low-toxic, environmentally friendly and efficient pesticide products can be developed on the basis of this compound, it will surely win a place in the pesticide market.
In the field of materials, due to its stable chemical structure and modifiability, it can be used to prepare high-performance organic materials. For example, in the field of optoelectronic materials, rational design and modification, or unique optical and electrical properties, provide new material options for organic Light Emitting Diodes, solar cells and other fields.
To make it shine in the market, it also faces many challenges. The synthesis process needs to be optimized to improve yield and reduce costs; the safety and Environmental Impact Assessment must also be comprehensive to ensure compliance with relevant regulatory standards. In this way, it is expected to open up broad prospects in the highly competitive market.