2-chloro-7-iodo-5-methyl-5h-pyrrolo[3,2-d]pyrimidine

2-Chloro-7-iodine-5-methyl-5H-pyrrolido [3,2-d] pyrimidine, according to its name, this is an organic compound. Its structure is constructed, with pyrrolido [3,2-d] pyrimidine as the parent nucleus. This parent nucleus is formed by fusing a pyrrole ring with a pyrimidine ring, just like the two rings intersect and integrate.
Above the 5 position, there is a methyl group, which acts as a branch and is added to the main structure. At the 2 position, the chlorine atom replaces it, and the 7 position is occupied by the iodine atom. In this way, the atoms are arranged in an orderly manner at specific positions, forming the unique chemical structure of 2-chloro-7-iodine-5-methyl-5H-pyrrolido [3,2-d] pyrimidine. This structural characteristic makes the compound have unique chemical properties and reactivity, and may have important uses in organic synthesis, medicinal chemistry and other fields, and can be used as a key intermediate for the synthesis of specific drugs or other organic compounds.

2-Chloro-7-iodine-5-methyl-5H-pyrrolido [3,2-d] pyrimidine is an organic compound. It has some unique physical properties.
Looking at its appearance, it may be a solid under normal conditions, because many organic compounds containing heterocycles and halogen atoms are in a solid state. The color state of this compound is either affected by atoms and chemical bonds in the molecular structure, or it is in a white to light yellow powder shape. Due to the action of intramolecular electron transitions and conjugated systems, it has specific absorption and reflection of light.
When it comes to melting point, due to the presence of van der Waals forces, hydrogen bonds and the induction effect of halogen atoms between molecules, the intermolecular force is enhanced, so the melting point is relatively high. The specific value may vary due to factors such as purity, but it is roughly in a certain temperature range, about 150 ° C - 250 ° C. This is due to the rigidity of the heterocyclic structure and the introduction of halogen atoms, which make the molecular arrangement more regular and tight, requiring higher energy to break the lattice structure and realize the phase transition.
In terms of solubility, because it is an organic compound, and the molecule contains hydrophobic groups such as halogen atoms and methyl groups, the solubility in water is very small. However, in organic solvents, due to the principle of similar miscibility, there may be a certain solubility in organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF). In dichloromethane, due to the adaptation of the force between the two molecules, it can be better dissolved; in DMF, the polarity of DMF can interact with the polarity of the compound to help it dissolve.
In addition, the density of the compound may be greater than that of water, because the relative atomic weight of iodine atoms in the molecule is large, the overall mass is increased, and the molecular structure is compact, so that its unit volume mass is greater than that of water. Its density may change at different temperatures, the temperature increases, the molecular thermal motion intensifies, the molecular spacing increases, and the density may decrease slightly.

The main synthesis methods of 2-chloro-7-iodine-5-methyl-5H-pyrrolido [3,2-d] pyrimidine are as follows.
First, the compound containing pyrrole and pyrimidine structures is used as the starting material, and chlorine and iodine atoms are introduced through halogenation reaction. First, take a suitable pyrrolido-pyrimidine parent, and under suitable reaction conditions, introduce chlorine atoms at specific positions with chlorinated reagents such as thionyl chloride. This process requires fine regulation of reaction temperature, time and reagent dosage to ensure that chlorine atoms are precisely replaced at the target position. Then, an iodizing agent, such as potassium iodide, is combined with an appropriate oxidizing agent to connect the iodine atom to the desired check point. During this period, factors such as the choice of reaction solvent and the pH of the reaction system all have a significant impact on the yield and selectivity of the reaction.
Second, it can be synthesized by the strategy of constructing a pyrrolidone-pyrimidine ring. First, pyrrole and pyrimidine fragments containing suitable substituents are prepared, and the two are connected into rings by a condensation reaction. For example, pyrrole derivatives with specific substituents interact with pyrimidine derivatives by nucleophilic substitution or cyclization. In the reaction, the activity of the substrate and the choice of the reaction catalyst need to be considered. Commonly used catalysts such as alkali catalysts can promote the activity of nucleophiles and promote the smooth progress of the reaction. After the ring system is constructed, chlorine and iodine atoms are introduced in a specific order through the halogenation step. This halogenation process also requires strict control of the reaction conditions in order to achieve the ideal synthesis effect.
Third, the method of gradually modifying the side chain and the substituents on the ring is adopted. Compounds with a basic pyrrolidone pyrimidine backbone are first synthesized, and then the groups on the side chain and ring are modified according to the structural requirements of the target product. If methyl is introduced first, it can be achieved by reacting with suitable substrates under basic conditions by methylating reagents such as iodomethane. After that, the chlorination and iodine reactions are carried out in an orderly manner, and the reaction conditions of each step are optimized, such as temperature, reaction time, and the proportion of reactants, etc., so as to achieve the synthesis of 2-chloro-7-iodine-5-methyl-5H-pyrrolido [3,2-d] pyrimidine.

2-Chloro-7-iodine-5-methyl-5H-pyrrolido [3,2-d] pyrimidine is used in medicine, chemical industry and other fields.
In the field of medicine, it is a key intermediate in organic synthesis and can be used to create new drugs. Due to its unique chemical structure, it can interact with specific biological targets or help develop therapies for specific diseases. For example, in the research and development of anti-tumor drugs, researchers hope to develop drugs that can precisely act on tumor cells and inhibit their growth and spread by modifying and optimizing their structures; in the research and development of anti-infective drugs, it is also expected to develop new drugs that inhibit or kill specific pathogens based on this substance.
In the chemical industry, it can be used to synthesize functional materials. Because of its specific electronic properties and chemical stability, it can be used as a basic unit for constructing special performance polymers or materials. For example, in the field of electronic materials, it may be used to synthesize materials with special electrical properties for the manufacture of new electronic components; in the field of optical materials, after rational design and modification, it may be used to endow materials with unique optical properties for the manufacture of optical sensors or optoelectronic devices.
Due to its unique structure, this compound also plays an important role in organic synthetic chemistry. Chemists can derive it through various chemical reactions to construct more complex and diverse organic molecular structures, opening up a broad space for the creation and properties of new substances. In short, the potential applications of 2-chloro-7-iodine-5-methyl-5H-pyrrolido [3,2-d] pyrimidine in many fields bring infinite possibilities for scientific research and industrial production.

2-Chloro-7-iodine-5-methyl-5H-pyrrolido [3,2-d] pyrimidine can be viewed from various perspectives in today's market prospects.
From the perspective of the pharmaceutical field, the nitrogen-containing heterocyclic structure often plays a key role in drug development. The pyrrolido-pyrimidine structure of this compound may have potential biological activity. For example, many anti-cancer drugs have a similar nitrogen-containing heterocyclic structure as the core structure, and their anti-cancer efficacy is demonstrated by their action on specific targets in cancer cells. Therefore, if further research and development are carried out, it may be able to find application opportunities in the fields of anti-cancer drugs and antiviral drugs. At present, there is a strong demand for new anti-cancer and anti-viral drugs in the pharmaceutical market. For example, the advent of new anti-cancer targeted drugs often causes a sensation in the market. If this compound is proved to be biologically active by research, it may open up a new drug market after subsequent optimization and clinical trials, and the prospects are quite promising.
In the field of materials science, organic compounds containing halogen atoms (chlorine, iodine) may be used to prepare functional materials. For example, organic optoelectronic materials, the introduction of halogen atoms may adjust the electronic structure and optical properties of materials. With the vigorous development of organic electronics, the demand for new organic optoelectronic materials is increasing. If this compound can be developed into organic Light Emitting Diode (OLED) materials, organic solar cell materials, etc., its market potential should not be underestimated in view of the wide application of OLEDs in the display field and the importance of solar cells to clean energy.
However, its market expansion also poses challenges. Synthesis of this compound may require complicated steps and special reagents, and the cost may remain high. And in the stage of biological activity research and material performance optimization, a lot of manpower, material resources and time are required. New drug development often takes several years or even decades from the laboratory to the market, and many links are uncertain.
Most importantly, 2-chloro-7-iodine-5-methyl-5H-pyrrolido [3,2-d] pyrimidine has broad market prospects in the fields of medicine and materials science, but it also needs to overcome the problems of synthesis cost and R & D cycle in order to truly realize its market value.