2-Chloroiodobenzene

Fengxi Chemical

Specifications

HS Code	911340
Chemical Formula	C6H4ClI
Molar Mass	239.45 g/mol
Appearance	Colorless to light yellow liquid
Density	1.98 g/cm³
Boiling Point	211 - 212 °C
Melting Point	−1 °C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ether, benzene
Flash Point	93 °C
Refractive Index	1.634 - 1.636
Odor	Characteristic aromatic odor

As an accredited 2-Chloroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	2 - chloroiodobenzene packaged in 500 - gram bottles for secure storage and transport.
Storage	2 - Chloroiodobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly sealed container to prevent vapor leakage. Since it is a chemical, store it separately from oxidizing agents, reducing agents, and reactive substances to avoid potential chemical reactions.
Shipping	2 - Chloroiodobenzene is shipped in well - sealed, corrosion - resistant containers. These are carefully packed to prevent breakage. Shipments follow strict hazardous material regulations, ensuring safe transport to destination.

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General Information

Historical Development

The history of 2-chloroiodobenzene
The evolution of chemistry, the variety of products, 2-chloroiodobenzene, although not the greatest quality, but its development also has considerable potential. In the past, chemistry was first emerging, the road of exploration was long, and the understanding of various compounds was still shallow.
At that time, chemical craftsmen focused on the field of halogenated aromatics. After years of experiments, the method of preparing 2-chloroiodobenzene was obtained. At the beginning, the process was difficult and the yield was quite low, and it was only available in a few well-researched laboratories.
After years, the chemical technology advanced, and new methods gradually emerged. The reaction conditions were optimized, the yield was increased, and the acquisition of 2-chloroiodobenzene was slightly easier to count than in the past. This compound is gradually used in the field of organic synthesis, or as an intermediate to help the production of various fine chemicals.
Looking at its process, from ignorance to gradually understanding its properties and making good use of its capabilities, it is like a microcosm of chemical development, from simple to complex, from obscure to bright, step by step, opening up endless possibilities for future generations.

Product Overview

2-Chloroiodobenzene is also an organic compound. Its color may be colorless to light yellow liquid, with a special odor. The structure of this substance, above the benzene ring, chlorine and iodine are in one place each, showing a unique chemical structure.
In the field of chemical industry, 2-chloroiodobenzene has a wide range of uses. It can be a key raw material for organic synthesis, and a variety of organic products can be derived through many chemical reactions. For example, in some catalytic reactions, it can be cleverly combined with other reagents to construct novel organic molecular structures, laying the foundation for the creation of new drugs, functional materials, etc.
However, its preparation is not easy, requiring delicate craftsmanship and precise operation. The reaction conditions, such as temperature, pressure, and the type and amount of catalyst, have a profound impact on the purity and yield of the product. During synthesis, all factors must be carefully controlled to achieve the desired results.

Physical & Chemical Properties

2 - Chloroiodobenzene is an organic compound. Looking at its physical and chemical properties, it is worth studying. In terms of physical properties, it is liquid at room temperature, with a specific color, taste and density. The color is yellowish and transparent, and the taste is slightly irritating. The density is higher than that of water, and it sinks at the bottom when placed in water.
When it comes to chemical properties, the activities of chlorine and iodine atoms in 2 - Chloroiodobenzene are very different. Chlorine atoms can participate in nucleophilic substitution reactions due to their electronegativity. When reagents attack, chlorine is easily replaced. Although iodine atoms are relatively stable, under certain conditions, in case of strong reducing agents, they can also react or deiodine and convert into other derivatives. Its chemical activity is derived from the interaction between benzene ring and halogen atom. The electron cloud distribution of benzene ring affects the activity of halogen atom, and halogen atom reacts against benzene ring. This interaction results in the unique physical and chemical properties of 2-Chloroiodobenzene, which is widely used in the field of organic synthesis.

Technical Specifications & Labeling

Jinyan 2 - Chloroiodobenzene This product, process specifications and identification (product parameters) are very important. Its process specifications are related to the synthesis method. It is necessary to take precise steps to control the temperature and time of the reaction, and select the appropriate solvent and reagent to ensure the purity of the product and the high yield.
Identification (product parameters) cannot be ignored. When the molecular formula is\ (C_6H_4ClI\) in detail, its molecular weight is accurate. Explain its properties, such as color state, should be off-white to light yellow crystalline powder. Mark its melting point range, about a certain range, to prove its purity. And it is necessary to clarify its use and what reaction and field it is suitable for. In this way, the essentials of 2-Chloroiodobenzene process specifications and identification (product parameters) can ensure that the product is of high quality and correct use.

Preparation Method

In the preparation of 2-Chloroiodobenzene, it is necessary to specify the method of its preparation, including the raw materials and the production process, the reaction steps and the catalytic mechanism.
The raw materials should be pure. If benzene is taken as the starting point, first use the method of chlorination to make chlorine into the benzene ring to obtain chlorobenzene. To obtain chlorobenzene, it is necessary to adjust the temperature and pressure. The iron salt is used as the catalyst, and the chlorine and benzene should be combined.
The second is iodine. In chlorobenzene, add an iodine source, and add a specific reminder, such as copper salts, to control the temperature and adjust the time. The key to this step is to promote the reaction between chlorobenzene and iodine, so that the position of iodine-substituted chlorobenzene is
Reaction steps, the precursor is washed to eliminate impurities. Add chlorobenzene, iodine source, and accelerator to the container, and dense it. Control the temperature and gradually rise, observe its reaction, and record its time change. After the reaction is completed, it is purified by fractionation, extraction, etc.
Catalytic mechanism, the ability of the accelerator, the energy barrier of the reaction is reduced, and the speed of the reaction is promoted. Such as copper salts, which can be combined with iodine and chlorobenzene to change their structure and make the reaction easy to enter.
Make 2 - Chloroiodobenzene, follow this path, and abide by the rules, and you can get good products.

Chemical Reactions & Modifications

The chemical and reverse modification of 2-chloroiodine-benzene is of great significance in chemical research. This compound, chloroiodine co-adheres to benzene, and its reverse properties are special. Past research has often focused on its reverse generation. In the usual method, under specific catalytic and reverse components, 2-chloroiodine-benzene can be nuclear-substituted and reversed, but its efficiency needs to be improved.
If you want to change it, you can start with catalytic modification. New catalytic materials are developed, which may promote the fusion of the reverse components and increase their performance. The distribution of the reverse dissolution, different dissolution, or reverse rate is also considered. These explorations are all about mining more chemical activity of 2-chloroiodine-benzene to optimize the synthesis.

Synonyms & Product Names

2-Chloroiodobenzene is also a chemical substance. Its same name and trade name are related to the research of our generation. This substance, the chlorine atom and the iodine atom are co-attached to the benzene ring, and the structure is unique and the properties are different.
In the academic world, 2-chloroiodobenzene is also known as another name. Or according to its structure, it is called by another name, but it all refers to this thing. As for the trade name, the industry merchants in order to recognize its characteristics, or take the name of Lang Lang, in order to facilitate identification and promotion.
Those who study this thing must understand the change of its same name and trade name. Depending on the name, or the different methods and uses involved. We should scrutinize all kinds of names in order to understand the whole picture of 2-chloroiodobenzene, explore its endless mysteries, and do our best for the advancement of chemistry.

Safety & Operational Standards

2-Chloroiodobenzene is also a chemical product. It is most important and important for safety and operation.
To make this 2-chloroiodobenzene, all materials must be pure and clean, and do not let it get mixed in or cause changes. The utensils to be used must also be cleaned, washed with hot water, and then dried without leaving moisture.
When combining this product, the amount of agent should be accurate, and it should be measured with a gauge, not too much or too little. Temperature control is also necessary, with a fixed degree, slowly rising and falling, not high or low.
Put 2-chloroiodobenzene in the bottle, close its mouth, and do not contact with air to avoid its deterioration. The storage place should be cool and dark, far from fire and heat.
Operators must wear protective gear, such as clothing, sleeves, mirrors, etc., to prevent them from touching the body or entering the eyes. If there is a splash, quickly wipe it with a cloth, and then rinse it with water. If you accidentally enter your eyes, get water in a hurry, and seek medical attention.
Do not discard waste materials and things, but deal with them with regulations to avoid contamination.
In short, the safety and operation regulations of 2-chloroiodobenzene should not be ignored. If you follow them, everything will go smoothly, and you will be afraid of harm if you violate them. Operators always keep it in mind to keep it safe.

Application Area

2 - Chloroiodobenzene is an important compound in organic synthesis, and its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize a variety of drug molecules with specific biological activities. Due to its unique chemical structure, it can participate in many key chemical reactions, providing an effective way for the creation of new drugs.
In the field of materials science, 2 - Chloroiodobenzene can be used to prepare special functional materials. Through the reactions it participates in, it can regulate the structure and properties of materials to meet the needs of different scenarios, such as the field of optoelectronic materials. In addition, in organic synthetic chemistry, it is often used as a starting material to build complex organic molecular structures through a series of reactions, creating conditions for organic synthetic chemists to explore novel compound structures and properties, and greatly promoting the development and progress of related fields.

Research & Development

I am in chemistry, and I have always had the heart to study it. Recently, I have been exploring this product of 2-Chloroiodobenzene. This material has unique properties and delicate structure, which has great potential for organic synthesis.
I have carefully investigated its reaction mechanism, and after repeated experiments, I have explored the changes under different conditions. It is found that when a specific catalyst and suitable temperature and pressure can trigger novel reaction paths and generate different products.
However, the road to research is not smooth. Many difficulties lie ahead, such as the reaction efficiency is not ideal, and the purity of the product needs to be improved. I will study diligently and explore unremittingly, hoping to find ways to optimize and enhance the application value of this substance in the field of synthesis, so as to promote the progress and development of chemical research, and contribute to the academic community. I hope to open up new avenues and make this substance shine in the chemical industry.

Toxicity Research

2 - Chloroiodobenzene is also a chemical substance. We study it carefully with its toxicity. Examine its nature, in the context of the chamber, and use the ancient law, and handle it with caution. The harm of its poison may be involved, and it is useful in the field of synthesis, but the toxicity cannot be ignored.

Use the method to reduce it, and reduce it to other things, to explore its poison.
In a certain reaction, it shows a specific appearance, or it can cause the surrounding things to be damaged in living things, or it may be damaged.
Many times, knowing that its toxicity is not bad, it must be used with caution to prevent the end. It is necessary for those who operate to understand the harm and keep the safety, so as to ensure the safety of chemical research and avoid the danger of toxicity.

Future Prospects

The Prospect of the Husband, In 2 - Chloroiodobenzene, there is no hope for this thing. In this world, there may be new developments in the use of this thing.
Its way of synthesis may be more delicate, and more expensive products may be obtained, and the cost may also be reduced. On top of the work, or on the basis of new materials, it can help to grow. The domain of, or as a new guide, to solve the disease of birth.
And its inverse nature, or can be explored in depth, to achieve unprecedented wonders. The new way is now, and the road ahead is bright. If you don't know what you will encounter, those who are not familiar with the science and technology will definitely move forward bravely, and in the future, make 2-Chloroiodobenzene its great use and the well-being of the world.

Where to Buy 2-Chloroiodobenzene in China?

As a trusted 2-Chloroiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 2-Chloroiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 2-chloroiodobenzene?

2-Chloroiodobenzene is one of the organic compounds. Its chemical properties are unique, due to the presence of chlorine atoms and iodine atoms in the molecule.
The substitution reaction is first discussed. The benzene ring has an electron cloud density, which can initiate electrophilic substitution. Although chlorine and iodine are electron-absorbing groups, the electron cloud density of the benzene ring is relatively high. Therefore, electrophilic reagents are easy to attack the ortho and para-sites and generate new substitution products. For example, when reacted with mixed acids of nitric acid and sulfuric acid, the nitro group or the ortho and para-sites. If the conditions are suitable, it can also undergo a Fu-gram alkylation reaction with halogenated alkanes catalyzed by Lewis acid, and an alkyl group is introduced into the benzene ring.
Chlorine atoms are more active. Under alkaline conditions, such as co-heating with sodium hydroxide aqueous solution, hydrolysis can occur, and chlorine is replaced by hydroxyl groups to form 2-hydroxyiodobenzene. Although iodine atoms are relatively stable, under the catalysis of specific metals, such as palladium catalysis, they can participate in coupling reactions, combine with compounds containing unsaturated bonds or other organometallic reagents, and form carbon-carbon bonds, which is of great significance in organic synthesis.
2-chloroiodobenzene is widely used in drug synthesis, material chemistry and other fields due to its unique chemical properties, helping organic chemists create a variety of compounds.

What are the main uses of 2-chloroiodobenzene?

2-Chloroiodobenzene, as well as organic compounds, is also useful in the fields of chemical industry, medicine and materials.
In the field of chemical industry, it is a key intermediate in organic synthesis. It can introduce multiple functional groups through nucleophilic substitution reaction, using its chlorine atom or iodine atom as the reaction check point. For example, it reacts with compounds containing hydroxyl groups and amino groups to form ether and amine derivatives, which is of great significance for the construction of complex organic molecular structures and lays the foundation for the creation of new compounds.
Pharmaceutical industry, its role is also important. Due to its unique structure, it can be chemically modified to obtain biologically active molecules. In the research and development of many drugs, 2-chloroiodobenzene is used as the starting material. After a series of reactions, drugs with curative effects on specific diseases are synthesized, such as the creation of anti-cancer and anti-infective drugs.
In the field of materials, it can participate in the preparation of polymer materials. Through polymerization reaction, it is integrated into the polymer chain to endow the material with special properties. Such as improving the electrical and optical properties of the material, so that the material can show excellent performance in electronic devices, optical materials, etc., such as the preparation of organic Light Emitting Diode (OLED) materials to improve the luminous efficiency and stability.
In summary, 2-chloroiodobenzene is an indispensable substance in the fields of chemicals, medicine and materials. It has a wide range of uses and promotes the development of various

What are the synthesis methods of 2-chloroiodobenzene?

2-Chloroiodobenzene is an important intermediate in organic synthesis. The synthesis method has been explored in the past, and the common methods mentioned above are as follows.
One is the halogenation method. Using benzene as the starting material, chlorobenzene is first chlorinated. In this step of chlorination, chlorine is often used as a chlorinating agent. Under the action of a suitable catalyst such as iron trichloride, the chlorine atom replaces the hydrogen atom on the benzene ring to obtain chlorobenzene. Then, the chlorobenzene reacts with the iodine source. For example, in the presence of specific oxidizing agents and catalysts, the iodine atom can be introduced into the ortho-position of chlorobenzene to generate 2-chloroiodobenzene. This oxidizing agent is often nitric acid, hydrogen peroxide, etc., The raw materials of this method are easy to obtain, but the reaction conditions may be more severe, and it needs to be finely regulated to obtain a higher yield.
The second is the cross-coupling method catalyzed by palladium. Halogenated aromatics are often used as substrates, such as o-chlorobrobenzene as the starting material, and cross-coupling reactions occur with iodizing reagents under the action of palladium catalysts. Commonly used palladium catalysts include tetra (triphenylphosphine) palladium, etc., and ligands or tri-tert-butylphosphine. In the reaction system, suitable bases, such as potassium carbonate, sodium carbonate, etc., need to be added to promote the reaction. This method has good selectivity, can efficiently synthesize 2-chloroiodobenzene, and is relatively friendly to the environment. It is widely used in the field < Br >
The third is the halogenation method guided by the guiding group. First, a guiding group, such as acetyl group, is introduced on the benzene ring to guide the position of the halogenation reaction. Acetylbenzene is used as raw material, chlorinated to obtain o-chloroacetylbenzene, and then the guiding group is removed. After the iodization step, 2-chloroiodobenzene is obtained. Although this process is slightly complicated, the substitution position of halogen atoms can be precisely controlled, and the purity and yield of the target product can be improved.
All synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to comprehensively consider factors such as raw material availability, cost, reaction conditions and product requirements, and choose the appropriate one to achieve the purpose of synthesizing 2-chloroiodobenzene.

What are the precautions for 2-chloroiodobenzene during storage and transportation?

For 2-chloroiodobenzene, many things need to be paid attention to during storage and transportation.
Its properties must be special, and when storing, the first environment should be selected. It should be placed in a cool and well-ventilated place. This may cause changes in its properties due to heat, or even cause danger. If the temperature is too high, it may accelerate its decomposition, or cause a reaction.
Furthermore, keep away from fires and heat sources. These substances may react violently in case of open flames, hot topics, or even cause combustion and explosion. And they should be stored in isolation from oxidants, active metal powders, etc. Due to the encounter between 2-chloroiodobenzene and oxidizing agent, or oxidation reaction, contact with active metal powder, or chemical reaction, safety is endangered.
Packaging should not be ignored. It should be ensured that the packaging is complete and sealed to prevent leakage. If there is a leak, it will not only waste materials, but also pollute the environment, and even threaten personal safety.
When transporting, the same caution should be used. The transportation vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. During driving, it should be protected from exposure to the sun, rain, and high temperature.
During loading and unloading, it must be handled lightly to prevent damage to the packaging and containers. If the packaging is damaged, 2-chloroiodobenzene leaks, which is quite difficult to deal And transport according to the specified route, do not stop in residential areas and densely populated areas, in case of leakage to cause harm to many people. In this way, the safety of 2-chloroiodobenzene during storage and transportation can be guaranteed.

What are the effects of 2-chloroiodobenzene on the environment and human health?

2-Chloroiodobenzene is also an organic compound. It has an impact on the environment and human health.
First of all, its impact on the environment. If this substance is released in the environment, it is persistent, difficult to degrade naturally, and easy to accumulate in soil and water bodies. In the soil, it may cause soil fertility to decline, affect the absorption of nutrients by plant roots, and then inhibit plant growth, causing vegetation types and quantities to change. In water bodies, it will endanger aquatic organisms. Its toxicity or damage to the physiological functions of aquatic animals such as fish and shellfish, interfere with their reproduction, growth and behavior, and in severe cases, it can cause a sharp decrease in the population and break the aquatic ecological balance. And because it can bioaccumulate, pass through the food chain, and the concentration gradually rises, eventually endangering the upper organisms of the food chain.
Re-discuss its harm to human health. People can be harmed by respiratory tract, skin contact or accidental ingestion of substances containing 2-chloroiodobenzene. Inhalation through the respiratory tract can irritate the mucosa of the respiratory tract, causing cough, asthma, breathing difficulties and other diseases. Long-term inhalation may damage lung function and increase the risk of respiratory diseases. When in contact with the skin, it may cause skin allergies, redness, swelling, and itching. If the skin is damaged, it is easier to penetrate into the body and damage the body's function. After ingesting by mistake, it will irritate the stomach, causing nausea, vomiting, abdominal pain, diarrhea and other gastrointestinal discomfort. And this substance may be potentially carcinogenic, long-term exposure to it, or cause gene mutations, increasing the risk of cancer. And because it can affect the nervous system, it can cause neurological symptoms such as headache, dizziness, fatigue, insomnia, etc., and impair cognitive and motor function.
Therefore, 2-chloroiodobenzene has potential threats to the environment and human health. It should be handled and used with caution to prevent the spread of its harm.