(2-ethyl-1-benzofuran-3-yl)(4-hydroxy-3,5-diiodophenyl)methanone

(2-Ethyl-1-benzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) methanone, an organic compound. Its chemical structure is composed of three parts cleverly spliced together.
One of them is 2-ethyl-1-benzofuran-3-yl. Benzofuran, like a delicate two-ring system, is fused by a one-furan ring and a benzene ring. The addition of an ethyl group at position 2 is like adding a special "decoration" to the structure of the two rings; at position 3, it is used as a key check point for subsequent connections.
The second is 4-hydroxy-3,5-diiodophenyl. The phenyl group is a hexahedral aromatic ring, which is connected to a hydroxy group at position 4, giving the structure a certain hydrophilicity; at positions 3 and 5, each is connected to an iodine atom. The large volume of the iodine atom and the unique electronic effect greatly affect the properties of the molecule.
The third is the methyl ketone group. Methyl ketone groups are like bridges, connecting 2-ethyl-1-benzofuran-3-group with 4-hydroxy-3,5-diiodophenyl to build a complete (2-ethyl-1-benzofuran-3-group) (4-hydroxy-3,5-diiodophenyl) methanone molecular structure. This structure endows the compound with unique physical and chemical properties, which may have unique applications and research values in organic synthesis, medicinal chemistry and other fields.

(2-Ethyl-1-benzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) methanone, which is an organic compound. Its physical properties are quite characteristic, let me go into detail.
Looking at its appearance, under normal circumstances, it is mostly in a crystalline state. Those with pure quality are white in color and regular in crystal shape, just like finely broken ice crystals, flickering under light, showing a pure state. However, if impurities are slightly mixed in, the color may be slightly dull, and the crystal shape may be slightly uneven.
As for the melting point, it has been strictly determined to be about a specific temperature range. The exact value of this temperature is actually an important physical sign of the compound. At the melting point, the intermolecular force can just be broken by thermal energy, the lattice structure disintegrates, and the substance gradually melts from the solid state to the liquid state. If the ambient pressure changes, the melting point also changes slightly, the pressure increases, the melting point rises slightly; the pressure decreases, the melting point drops slightly.
Determination of boiling point is also of great significance. When the boiling point is reached, the compound changes from liquid to gas state, and under specific pressure conditions, its boiling point is a predetermined value. This value reflects the energy required for the molecule to break free from the liquid phase and escape into the gas phase.
In terms of solubility, this compound exhibits good solubility in organic solvents such as ethanol and acetone. Ethanol is as agile as water, and acetone has a unique ability to dissolve. Both can form intermolecular forces with the compound molecules, such as hydrogen bonds, van der Waals forces, etc., to uniformly disperse the compound molecules. In water, the solubility is not good. Because the polarity of water does not match the molecular structure of the compound, it is difficult for water molecules to tightly bind to the compound molecules, resulting in a state of suspension or precipitation in water. The density of
is also an important physical property of the compound. Its density value reflects the mass of the substance contained in a unit volume, and this value is closely related to the molecular weight and molecular arrangement of the compound.
The physical properties of this (2-ethyl-1-benzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) methanone are of key significance for its application in chemical and pharmaceutical fields.

(2-Ethyl-1-benzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) methanone is an organic compound. This substance has a wide range of uses and is often a key intermediate for the creation of new drugs in the field of medicinal chemistry. Due to its unique molecular structure, it can interact with specific targets in organisms, or can develop drugs against various diseases, such as inflammation, tumors, etc.
In the field of materials science, it may also have potential applications. Because it contains specific functional groups, or can be chemically modified to obtain materials with special properties, such as optical materials, conductive materials, etc. In organic synthetic chemistry, this compound can be used as an important raw material to build more complex and special functional organic molecules through various chemical reactions.
Furthermore, at the level of scientific research, it is an excellent substrate for studying the mechanism of organic reactions. Chemists can use it as a starting material to gain insight into the breaking and formation of chemical bonds during the reaction process, thereby deepening their understanding of the nature of organic reactions and contributing to the development of organic synthesis methodologies. In short, (2-ethyl-1-benzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) methanone has important value and potential application prospects in many fields.

To prepare (2-ethyl-1-benzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) methyl ketone, there are various methods. The common method is to start with benzofuran derivatives and iodophenol derivatives.
Take benzofuran first, and in a suitable solvent, remove hydrogen with a strong base to generate benzofuran negative ions. This negative ion has high activity and can react with halogenated alkanes to introduce ethyl to obtain 2-ethyl-1-benzofuran. This step requires controlling the reaction temperature and time to avoid side reactions.
Another phenolic compound is taken, and under suitable conditions, iodized with an iodine source to obtain 4-hydroxy-3,5-diiodophenol. The iodine source can be combined with an appropriate oxidizing agent such as hydrogen peroxide.
Then, the 2-ethyl-1-benzofuran-3-position is connected to the 4-hydroxy-3,5-diiodophenyl group by acylation reaction. Acyl halide or acid anhydride can be used, and the Foucault acylation reaction occurs under the catalyst of Lewis acid, such as aluminum trichloride. During the reaction, the choice of solvent and the amount of catalyst need to be finely regulated to achieve the best yield and selectivity.
Or there are other methods, such as coupling reactions catalyzed by transition metals. With benzofuran-containing halides and 4-hydroxy-3,5-diiodophenyl-containing borates or other nucleophiles, carbon-carbon bonds are formed under the catalysis of transition metals such as palladium and nickel, and the target product is constructed. In this process, the choice of ligands has a great impact on the reaction activity and selectivity. Depending on the specific situation, the appropriate ligands need to be screened to make the reaction efficient.

The toxicity of (2-ethyl-1-benzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) methanone is difficult to determine.
To determine whether its toxicity is present or not, many complicated tests are required. First, it is reasonable to take animals as a test to observe their physiological reactions after ingestion or exposure to this compound, such as eating, activity, and organ state. If the animal is sluggish, eating sharply reduced, and the organs are damaged, it may be toxic. Second, cell experiments are also indispensable to apply this compound to specific cells to observe its effects on cell growth, proliferation, and apoptosis. If cell growth is inhibited and apoptosis is abnormal, it can also be evidence of toxicity.
However, I do not have detailed information on this compound today, and I do not know whether there are relevant toxicity studies by predecessors. If it has been proven to be harmful to organisms in previous studies, or is structurally similar to known toxic compounds, it should be carefully assumed that it is toxic. On the contrary, if there is no such clue, it should not be ignored, and it must be determined by rigorous tests. In short, it is difficult to determine its toxicity based on this name alone, and it must be based on scientific experiments to obtain the true truth.