2 Fluoro 3 Iodotoluene

2-Fluoro-3-iodotoluene is also an organic compound. It has a wide range of main uses and is often a key raw material in the field of organic synthesis.
In the field of organic synthesis, 2-fluoro-3-iodotoluene can participate in many reactions. Such as nucleophilic substitution reactions, because of the activity of fluorine and iodine atoms in the structure, it can interact with various nucleophiles to introduce other functional groups, and then construct complex organic molecular structures. This is particularly important in the process of drug development. The creation of many new drugs relies on such reactions to generate intermediates with specific activities and structures.
Furthermore, in the field of materials science, it also has its application. After a specific chemical reaction, 2-fluoro-3-iodotoluene can be converted into materials with special properties. Or as an optoelectronic material, it can be used in optoelectronic devices, such as Light Emitting Diode, solar cells, etc., giving the material unique optical and electrical characteristics and improving the performance of the device.
And in the field of fine chemicals, 2-fluoro-3-iodotoluene is also indispensable. It can be used to synthesize special dyes, fragrances and other fine chemicals. Taking the synthesis of dyes as an example, through the modification and transformation of their structures, dyes with bright colors and good stability can be prepared to meet the needs of textile, printing and other industries.
In short, 2-fluoro-3-iodotoluene, with its unique chemical structure, plays an important role in many fields such as organic synthesis, materials science, fine chemicals, and contributes a lot to the development of various industries.

2-Fluoro-3-iodotoluene is one of the organic compounds. Its physical properties are as follows:
Looking at its color state, under room temperature and pressure, it is usually a colorless to light yellow transparent liquid. The appearance is pure and has a specific luster, and there are no impurities visible to the naked eye. Smell, there is a special organic odor, but this odor is not a strong pungent odor, and only has the unique smell of this type of compound.
In terms of its melting point, the melting point is about -40 ° C to -30 ° C. This low temperature allows the substance to remain liquid in common low-temperature environments. The boiling point is about 200 ° C to 210 ° C. A higher boiling point indicates that the intermolecular force is strong, and more energy is required to vaporize it. In terms of density,
is about 1.8-1.9g/cm ³, which is higher than the density of water, so if mixed with water, this substance will sink to the bottom of the water.
Solubility is also an important physical property. It has little solubility in water because it is an organic compound with little force between water molecules and does not have good hydrophilicity. However, it has good solubility in organic solvents such as ethanol, ether, dichloromethane, etc. Due to the principle of similarity and compatibility, the substance is similar to the molecular structure and polarity of organic solvents and is miscible. In addition, 2-fluoro-3-iodotoluene is volatile to a certain extent. In an open environment, it will slowly evaporate into the air, but the volatilization rate is not very fast. This property also affects its storage and use environment.

2-Fluoro-3-iodotoluene is also an organic compound. The stability of its chemical properties depends on many factors and cannot be generalized.
In terms of structure, fluorine atoms and iodine atoms are connected to the benzene ring of toluene. Fluorine atoms have strong electronegativity, which can reduce the electron cloud density of benzene ring and slightly reduce the electrophilic substitution activity of benzene ring; although iodine atoms also have electron-absorbing induction effect, their atomic radius is large and the conjugation effect is relatively weak. The influence of these two makes the electron cloud distribution of benzene ring different from that of toluene, which affects the reaction activity to a certain extent.
At the stability end, the carbon-fluorine bond energy is quite high, which is difficult to break and can increase molecular stability; while the carbon-iodine bond energy is relatively low, and under specific conditions, or easily broken bonds participate in the reaction. Therefore, 2-fluoro-3-iodotoluene can exist stably under normal conditions such as normal temperature and pressure, dark, and oxygen and reducing agents; in case of high temperature, strong acid and base, strong oxidizing agent or reducing agent, or chemical reaction, the stability is lost.
In nucleophilic substitution reactions, iodine atoms are easily replaced by nucleophiles due to carbon-iodine bond activity; in electrophilic substitution reactions, the change of electron cloud density of benzene ring also affects the reaction check point and rate. In summary, the stability of 2-fluoro-3-iodotoluene is not absolute and varies with the environment and reaction conditions.

To prepare 2-fluoro-3-iodotoluene, it can be obtained from the following numbers.
First, start with o-methylaniline. First, o-methylaniline is heated with hydrofluoric acid and sodium nitrite, and then reacted with diazotization to obtain o-methylfluorobenzene. Subsequently, iodine atoms are introduced into specific positions in its benzene ring, and electrophilic substitution reactions can be used. In the presence of suitable catalysts such as iron powder or ferric chloride, iodine atoms will selectively enter the ortho-position of fluorine atoms and methyl intersites, thereby preparing 2-fluoro-3-iodotoluene.
Second, o-fluorotoluene is used as the starting material. In the presence of a suitable catalyst and base, 2-fluorotoluene and iodomethane are first alkylated by Fu-g, and methyl groups are introduced into the benzene ring to generate 2-fluoro-3-methyliodobenzene. This process requires attention to the control of reaction conditions so that methyl groups are selectively introduced into the desired position.
Third, 3-iodo2-methylbenzoic acid is used as the starting material. It is first decarboxylated to remove the carboxyl group and convert it into 2-methyl-3-iodobenzene. Afterwards, a halogen exchange reaction is used to react with a fluorinating reagent to replace other halogen atoms at a specific position on the benzene ring with fluorine atoms, resulting in 2-fluoro-3-iodotoluene.
These methods have their own advantages and disadvantages, and need to be selected according to actual needs and conditions. In the reaction, attention should be paid to the control of conditions, the purity of raw materials and the separation and purification of products to obtain 2-fluoro-3-iodotoluene with higher yield and purity.

I think what you are asking is that 2-fluoro-3-iodotoluene is in the market price range. However, the price of this chemical often changes due to various reasons, and it is difficult to directly determine the value.
First, the situation of supply and demand has a great impact. If there are many applicants for this product, but there are few suppliers, the price will rise; on the contrary, the supply exceeds the demand, and the price may drop. Second, the difficulty of preparation also affects its price. If the preparation requires complicated methods and high materials, the price will be high; if it is easy to prepare, the cost will be low, and the price will be low. Third, the state of market competition cannot be ignored. If there are many competitors in the market, in order to compete for customers, or reduce the price; if it is an exclusive business, the price may be high. Fourth, the fluctuation of raw material prices is also related. If the price of raw materials required for the preparation of this product rises, the price of the finished product will also rise; if the price of raw materials falls, the price of the finished product may drop.
As for this 2-fluoro-3-iodotoluene, it is common in the market, or it is laboratory reagent grade, or industrial grade. Reagent grade, due to its high purity and strict requirements for impurities, the price may be higher than industrial grade. Roughly speaking, the price of laboratory reagent grade may be more than tens of yuan to hundreds of yuan per gram; for industrial grade, depending on the quantity, if the batch is large, the price per ton may be between tens of thousands of yuan. However, these are all approximate numbers. The actual price should be based on the real-time market situation and consult the supplier in detail to get an accurate price.