2-Fluoro-4-Bromoiodobenzene

Fengxi Chemical

Specifications

HS Code	207771
Chemical Formula	C6H3BrFI
Appearance	Colorless to light yellow liquid
Boiling Point	Approximately 220 - 225°C
Melting Point	N/A (usually liquid at room temperature)
Density	Around 2.3 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Stability	Stable under normal conditions, but avoid strong oxidizing agents
Purity	Typically high - purity products are around 98% or above

As an accredited 2-Fluoro-4-Bromoiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 2 - fluoro - 4 - bromoiodobenzene packaged in a sealed glass bottle.
Storage	2 - Fluoro - 4 - bromoiodobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and strong oxidizing agents. Store in a tightly sealed container to prevent vapor leakage. Due to its potentially hazardous nature, it should be stored separately from incompatible substances, preferably in a dedicated chemical storage cabinet for halogenated aromatic compounds.
Shipping	2 - fluoro - 4 - bromoiodobenzene is shipped in accordance with strict chemical regulations. Packed in well - sealed, corrosion - resistant containers, it's transported by carriers trained in handling hazardous chemicals to ensure safe delivery.

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General Information

Historical Development

I have tried to study the technology of chemical industry. In 2 - Fluoro - 4 - Bromoiodobenzene, I thought about the evolution of its history. In the past, the chemical industry was just emerging, and the research of this product was rare, the technology was not ready, and the progress was difficult. As the years passed, the wise men made unremitting efforts, and the research method gradually refined. Or explore new choices of raw materials, or study the wonderful theory of reaction. After many trials and errors, we began to optimize the road. The synthesis method is clumsy and clever, and the yield is also rising. Quantities that were difficult to obtain in the past can now be prepared in large quantities and applied to various fields, such as medicine and materials. This is all due to the efforts of researchers over the ages, which has made the development of 2-Fluoro-4-Bromoiodobenzene widely used, adding a brilliant pen to the history of chemical industry.

Product Overview

2 - Fluoro - 4 - Bromoiodobenzene is a unique chemical substance. Its appearance may be colorless to slightly yellow liquid, with specific physical and chemical properties. This substance plays an important role in the field of organic synthesis and is often used as a key intermediate.
In terms of its structure, fluorine, bromine and iodine atoms on the benzene ring occupy specific positions, giving it unique reactivity. With this property, complex organic molecular structures can be constructed through various chemical reactions.
Preparation of this compound requires a fine synthesis process and strict control of reaction conditions, such as temperature, catalyst and reactant ratio. In scientific research and industrial production, accurately grasping its properties and preparation methods is of great significance for expanding the path of organic synthesis and developing new materials, which is an indispensable part of chemical research.

Physical & Chemical Properties

2 - Fluoro - 4 - Bromoiodobenzene is an organic compound with unique physical and chemical properties. Its appearance may be colorless to light yellow liquid, which is relatively stable at room temperature and pressure.
From the perspective of physical properties, the substance has a specific melting point, boiling point and density. Its melting point is suitable, so that it may be solid in a specific temperature environment, and will vaporize when heated to near the boiling point. The density determines its position in the mixed system.
In terms of chemical properties, it has certain reactivity due to the presence of halogen atoms such as fluorine, bromine, and iodine. It can participate in nucleophilic substitution reactions, and halogen atoms can be replaced by other nucleophiles to form new organic compounds, which are widely used in the field of organic synthesis. Due to its special structure and properties, it has important research value and application potential in many disciplines such as medicinal chemistry and materials science.

Technical Specifications & Labeling

For 2-fluoro-4-bromoiodobenzene, it is also a new product. Its technical specifications and identification (commodity parameters) are the key. To make this product, it is necessary to carefully select the raw materials. Whether it is pure or not depends on the quality of the finished product.
In the process specification, the reaction steps must be carried out in sequence, and the temperature control and speed regulation are fixed. If the reaction temperature is too high, the product will be variable, and if it is too low, the reaction will be slow. Every step of transformation needs to be carefully observed.
In terms of identification, when its characteristics are clear, the color, taste and state should be confirmed. Its purity geometry and what impurities are are all important parameters. In addition, its physical and chemical properties, melting point, solubility, etc., cannot be ignored. In this way, the process specifications and labels of 2-fluoro-4-bromoiodobenzene can be determined, which lays the foundation for its research and application.

Preparation Method

To prepare 2 - Fluoro - 4 - Bromoiodobenzene, it is necessary to clarify its raw materials and production process, reaction steps and catalytic mechanism.
Prepare raw materials, based on compounds containing fluorine, bromine and iodine, supplemented by appropriate solvents and catalysts. In the production process, initially, the temperature is controlled in a specific range, so that the reactants are mixed evenly and the preliminary reaction is promoted. Next, adjust the reaction conditions, such as changing temperature and pressure, and introduce a specific catalyst to make the reaction proceed in a predetermined direction.
The first raw material ratio of the reaction step, accurately weigh the reactants to ensure accurate stoichiometry. Then, add them in sequence in the reactor, turn on stirring, and heat up. When the predetermined temperature is reached and the constant temperature reaction is several times.
The catalytic mechanism depends on the selected catalyst. It can reduce the activation energy of the reaction and accelerate the reaction process. Or form an intermediate state with the reactants. After a series of changes, the final product is 2-Fluoro-4-Bromoiodobenzene, and the purity and yield of the product are guaranteed.

Chemical Reactions & Modifications

Nowadays, scholars have studied 2 - Fluoro - 4 - Bromoiodobenzene. Its transformation and change are of great importance to our generation.
In the chemical reaction, the properties of 2 - Fluoro - 4 - Bromoiodobenzene determine its path. Atoms of fluorine, bromine, and iodine, above the benzene ring, each show their own abilities. Fluorine has strong electronegativity, which changes the electron cloud of the benzene ring and affects the electrophilic reaction. Bromine and iodine, although they have different properties, also participate in the reaction, or lead to the attack of the pro-nuclear, or are the basis for departure.
If you want to be good at something, you must understand its change. The conditions of the reaction, such as temperature, pressure, catalyst, etc., are all related to its formation and speed. Appropriate temperature can promote the smooth reaction, and the catalyst can reduce the activity and make the reaction easy to start.
And the reaction of this thing can change its structure to obtain new substances. Or adjust the connection of atoms, or increase the group of functions, so that its nature is different and more widely used. Scholars should study this ingenuity in detail, in order to explore the wonders of the reaction, seek the change of physical properties, and contribute to the progress of the chemical industry.

Synonyms & Product Names

2 - Fluoro - 4 - Bromoiodobenzene is a chemical substance that I have been focusing on recently. In the field of chemistry, the same substance often has different names, which is also where the diversity of chemical naming lies.
The alias of this substance, or according to its structural characteristics, synthesis path, or because of its usual use, there are many expressions. The origin of the commercial name is also related to the market and use. However, its root cause refers to the chemical of this specific structure.
Although the names are different but the same, many synonymous names reflect the inheritance and development of chemical knowledge. Chemists give it different names according to their habits and research purposes. In academic exchange, production practice, and clear synonyms and trade names, we can ensure correct communication and orderly research. We should study in depth and grasp the various titles of this chemical substance to achieve the best environment of chemical research.

Safety & Operational Standards

2-Fluoro-4-bromoiodobenzene is also a chemical substance. Its safe production and operation specifications cannot be ignored.
When preparing this substance, all reagents and utensils must be clean and pure to prevent impurities from mixing, causing reaction errors, and maintaining the quality of the product. During operation, it is suitable to use it in a well-ventilated place. Many chemicals are toxic and volatile. Good ventilation can reduce the accumulation of harmful gases and ensure the health of the operator.
When using it, the measuring device must be accurate, and it must be taken according to the square. After weighing, that is, cover the container tightly to prevent it from touching the air for a long time and causing qualitative change.
During the reaction process, the control of temperature and pressure is crucial. According to the reaction characteristics, adjust to the appropriate temperature and pressure, be punctual and abide by regulations, and do not leave without permission. If the temperature and pressure change suddenly, follow the plan quickly to prevent accidents.
Product storage is also subject to regulations. Choose a well-sealed container with suitable materials, avoid light, high temperature, and humidity, and place it in a cool and dry place. Store it separately according to categories, and prohibit the mixing of reactive materials.
Handle this object with care to avoid collisions and falls, and prevent container damage and material leakage. If there is a leak, quickly start the emergency system, the operator wearing protective equipment, according to the amount of leakage, physical properties, take appropriate methods to clean up, do not let the pollution spread.
In short, the safe production and operation of 2-fluoro-4-bromoiodobenzene is related to the safety of the operator and the quality of the product. It must follow the norms and must not be slack at all.

Application Area

2 - Fluoro - 4 - Bromoiodobenzene is also a chemical substance. Its use, in the field of, can be used as a raw material. With its unique chemical properties, it can be used to create more and more reactions, helping to create new research, or it can be used for the generation and solution of common diseases. In the field of material science, it also has its own uses. It can be used by specific methods to make materials more unique, such as better performance, light, etc., to add new materials. And in the synthesis of, often used in the, to help the family to generate molecules, promote the synthesis of step, in many fields, all develop its value can not be ignored.

Research & Development

In recent years, I have studied a lot of chemical substances, and now I am only discussing the product 2 - Fluoro - 4 - Bromoiodobenzene. Its unique nature, in the field of organic synthesis, has attracted the attention of chemists.
I first dealt with this product, observed its structure in detail, and understood the wonder of its atomic arrangement. I also explored its reaction mechanism, and through many experiments, I knew the law of its interaction with various reagents. Under a specific temperature and pressure, it meets with nucleophiles, and the change of normal substitution and its location selection can be traced.
In order to promote the development of this product, I discussed with my colleagues. The method of optimizing the synthesis strives to reduce its cost and increase its yield. And research its new use, hope to open up a new world in the fields of medicine and materials. With time, it will be able to make 2-Fluoro-4-Bromoiodobenzene shine and add to the progress of chemistry.

Toxicity Research

Recently, 2 - Fluoro - 4 - Bromoiodobenzene has been studied, and its toxicity is quite important. If the chemical substance has unknown toxicity, it will be dangerous to use it.
View 2 - Fluoro - 4 - Bromoiodobenzene has a unique molecular structure, and halogen atoms are concentrated on a benzene ring. Fluorine, bromine, and iodine are active in nature, or make the substance have special toxicity.
Use experimental methods to observe its effects on organisms. Use various cell lines to measure its cytotoxicity, and observe how the growth and proliferation of cells are disturbed by it. Take animals as models to observe the changes in physiological functions and organs after ingesting this substance.
After a series of investigations, it can be known that the toxic behavior of 2-Fluoro-4-Bromoiodobenzene can provide a basis for the safety or regulation of future use to avoid its harm to life and the environment.

Future Prospects

Today there is a thing called 2 - Fluoro - 4 - Bromoiodobenzene, which is a product of chemistry. I look at this thing, although it is in the current world, the prospect of its future is really reverie.
This thing may open up a new path in the field of chemical industry. With time, study its properties and reason, or it can be used for exquisite synthesis. The field of organic, or can build novel structures and make unique materials. It is also possible in the field of medicine. Based on it, a special medicine may be made to solve the pain of everyone.
In the future world, science and technology will be new every day. If we can make good use of this thing and borrow advanced techniques, we may be able to add luster to industry and benefit people's livelihood. The road ahead is long, but I look forward to it. Looking forward to the future, I will see it shine and show extraordinary capabilities in various fields, which will live up to our expectations for research.

Where to Buy 2-Fluoro-4-Bromoiodobenzene in China?

As a trusted 2-Fluoro-4-Bromoiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 2-Fluoro-4-Bromoiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-fluoro-4-bromoiodobenzene?

2-Fluoro-4-bromoiodobenzene is also an organic compound. Its main uses cover the following numbers.
In the field of organic synthesis, this compound is often an important intermediate. Due to the unique reactivity of halogen atoms (fluorine, bromine, iodine), they can participate in a variety of chemical reactions. Such as nucleophilic substitution reactions, although fluorine atoms have high electronegativity, the aromatic ring in which they are located can be replaced with nucleophilic reagents under appropriate conditions to introduce new functional groups; bromine and iodine atoms can also play a key role in many reactions, such as the Ullmann reaction and the Suzuki reaction. Through these reactions, complex organic molecular structures can be constructed for the creation of fine chemicals such as drugs and materials.
In pharmaceutical chemistry, 2-fluoro-4-bromoiodobenzene may be an important structural fragment of lead compounds. The introduction of halogen atoms can change the physical and chemical properties of compounds, such as fat solubility, polarity, etc., which in turn affect their biological activity and pharmacokinetic properties. For example, fluorine atoms can enhance the interaction between compounds and biological targets, improve the efficacy of drugs; bromine and iodine atoms may affect the spatial configuration of molecules and play an important role in the compatibility of drugs and receptors.
In the field of materials science, it may be used to prepare materials with special functions. For example, in organic optoelectronic materials, due to the presence of halogen atoms, the electron cloud distribution of molecules can be adjusted, which affects the optical and electrical properties of the material. Through appropriate reactions, it can be connected to the polymer skeleton, or the material can be endowed with unique luminescence, electrical conductivity and other properties, used in the manufacture of organic Light Emitting Diodes (OLEDs), organic solar cells and other devices.
In summary, the special reactivity of 2-fluoro-4-bromoiodobenzene halogen atoms has important uses in organic synthesis, medicinal chemistry, materials science and other fields, and is an indispensable compound for the development of organic chemistry research and related industries.

What are the physical properties of 2-fluoro-4-bromoiodobenzene?

2-Fluoro-4-bromoiodobenzene is one of the organic compounds. Its physical properties are quite important, let me explain in detail.
First of all, its phase state and color. At room temperature and pressure, 2-fluoro-4-bromoiodobenzene is mostly liquid, and it often has a clear color, but it may vary slightly due to impurities. Although its smell is not as pungent as a malodorous thing, it also has a unique smell. This smell is caused by the particularity of the molecular structure and often needs to be judged by a professional sense of smell.
As for its boiling point, it is about a specific value range. Due to the interaction between atoms in the molecule, such as the change of molecular polarity caused by the electronegativity difference of halogen atoms, its boiling point is different. Generally speaking, its boiling point is slightly higher than that of ordinary small molecule organics, due to the increase of halogen atoms and the increase of intermolecular forces. According to experimental measurements and theoretical calculations, its boiling point is in a certain range, but the exact value depends on precise experimental conditions.
Melting point is also an important physical property. The melting point of this compound is affected by molecular arrangement and interactions. The spatial position of halogen atoms and electronic effects make the interaction between molecules complex. Therefore, its melting point also has a specific value. At this temperature, the substance is a solid state, and when the temperature rises above the melting point, it gradually converts into a liquid state.
Density cannot be ignored. The density of 2-fluoro-4-bromoiodobenzene is higher than that of water. Due to the large relative atomic weight of the halogen atoms in the molecule, the mass per unit volume increases. The exact value of its density can be obtained by experimental measurement. In the fields of chemical industry and scientific research, this density data is related to the mixing and separation of the substance with other substances.
In terms of solubility, 2-fluoro-4-bromoiodobenzene has a certain solubility in organic solvents such as ethanol and ether. The cover has a certain hydrophobicity due to its molecular structure, and the force between the molecules of the organic solvent is suitable, which is conducive to dissolution. In water, its solubility is poor, which is due to the difference between the polarity of the water molecule and the molecular polarity of the compound, as well as the hydrophobic action of the halogen atom.
In summary, the physical properties of 2-fluoro-4-bromoiodobenzene, such as phase state, odor, boiling point, melting point, density and solubility, are determined by its unique molecular structure, and are of great significance in many fields such as organic synthesis and materials science.

What are 2-fluoro-4-bromoiodobenzene synthesis methods?

The synthesis method of 2-fluoro-4-bromoiodobenzene has always been an ancient method. To make this substance, you can start with the halogenation reaction of benzene.
First, using benzene as the starting material, the bromine atom is introduced first. Under the catalysis of iron or iron tribromide, the electrophilic substitution reaction between benzene and bromine occurs to obtain bromobenzene. In this reaction, iron and bromine react to form iron tribromide, which is an electrophilic agent and prompts the hydrogen on the benzene ring to be replaced by bromine.
After obtaining bromobenzene, the halogen exchange method can be used to introduce fluorine atoms. Bromobenzene is used as a substrate to react with fluorine sources such as potassium fluoride in a specific organic solvent such as dimethyl sulfoxide (DMSO). At this time, bromine and fluorine are exchanged to obtain fluorobromobenzene. This reaction requires attention to control the reaction temperature and time to ensure the smooth progress of the fluoride reaction and reduce side reactions.
Fluorobromobenzene is obtained, and finally iodine atoms are introduced. A nucleophilic substitution reaction can be used to react fluorobromobenzene with sodium iodide or potassium iodide in a suitable solvent such as acetone. In this reaction, iodine ions act as nucleophiles to attack the carbon attached to the bromine on the benzene ring, causing the bromine to leave, resulting in 2-fluoro-4-bromoiodobenzene In the
synthesis process, it is crucial to control the reaction conditions at each step. Temperature, choice of solvent, and proportion of reactants all affect the yield and selectivity of the reaction. After each step of the reaction, it needs to be separated and purified to remove impurities and obtain a purified product before the purpose of synthesizing 2-fluoro-4-bromoiodobenzene can be achieved.

2-fluoro-4-bromoiodobenzene What are the precautions during storage and transportation?

2-Fluoro-4-bromoiodobenzene is also an organic compound. During storage and transportation, many matters must be paid attention to.
First, storage, because of its chemical activity, should be placed in a cool, dry and well-ventilated place. Avoid direct sunlight to prevent chemical reactions caused by light and deterioration. This compound may be sensitive to temperature, and high or low temperatures can affect its stability, so the storage temperature should be controlled within a specific range. In addition, it must be stored in isolation from oxidants, reducing agents, acids, bases and other substances. Due to its chemical properties, contact with such substances can easily trigger violent reactions, and even pose a risk of safety. The storage place should also be equipped with suitable fire and leakage emergency treatment equipment to prevent accidents.
As for transportation, it must be operated in accordance with relevant regulations and standards. The transportation container must be strong and well sealed to prevent leakage. The packaging materials selected must be able to withstand vibration, collision and temperature changes to ensure the safety of substances in transit. Transport personnel should be familiar with the characteristics of the compound and emergency treatment methods, and in case of leakage and other conditions, they can quickly and properly dispose of it. During transportation, close attention should also be paid to conditions such as ambient temperature and humidity to avoid adverse effects of extreme environments.
In conclusion, the storage and transportation of 2-fluoro-4-bromoiodobenzene is related to safety and quality, and all details should not be ignored. It must be done with a rigorous attitude and correct methods to ensure safety.

2-fluoro-4-bromoiodobenzene impact on the environment and human health

2-Fluoro-4-bromoiodobenzene is also an organic compound. Its impact on the environment and human health is of great concern to everyone.
At the environmental end, if this compound is released in nature, or stored in soil and water bodies. Due to its halogen atom, its chemical properties may be relatively stable, and it is difficult to be rapidly decomposed by natural microorganisms, so it can be retained in the environment for a long time, causing environmental pollution. If it enters the water body, it may affect the survival and reproduction of aquatic organisms. Aquatic organisms are extremely sensitive to changes in water quality. This compound may interfere with their physiological processes, such as affecting their respiratory and reproductive systems, reducing the population. And through the food chain, its concentration may be enriched in high-nutrient organisms, endangering the balance of the entire ecosystem.
As for human health, 2-fluoro-4-bromoiodobenzene may be ingested into the human body through respiration, skin contact and diet. The presence of halogen atoms may make it toxic. After entering the human body, it may interfere with normal physiological and biochemical reactions. For example, it may affect the metabolic process of cells, hinder the activity of enzymes, and cause abnormal cell function. Long-term exposure may damage the human nervous system, causing symptoms such as headache, dizziness, and fatigue. It may also interfere with the endocrine system, affecting the normal secretion and regulation of hormones, which is related to human growth and development and reproductive function. And studies have shown that some halogen-containing organic compounds have potential carcinogenicity. Although the carcinogenicity of this compound has not been confirmed, the latent risk cannot be ignored. Therefore, the impact of this compound on the environment and human body should be continuously monitored and studied to ensure the ecological environment and human health.