2 Fluoro 4 Iodobromobenzene
Iodobenzene

2 Fluoro 4 Iodobromobenzene

Fengxi Chemical

Specifications

HS Code

511817

Chemical Formula C6H3BrFI
Molecular Weight 286.89
Appearance A colorless to light yellow liquid (usually)
Boiling Point Data varies, around 200 - 220°C (approximate)
Solubility In Water Insoluble (organic halide, non - polar)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Vapor Pressure Low at room temperature
Chemical Formula C6H3BrF
Molecular Weight 221.99
Appearance Liquid
Boiling Point Approx. 180 - 185 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane
Vapor Pressure Low vapor pressure
Stability Stable under normal conditions
Chemical Formula C6H3BrF
Molar Mass 222.99 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 190 - 192 °C
Density 1.992 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Purity Typically high - purity in commercial products
Chemical Formula C6H3BrF I
Appearance A colorless to light yellow liquid
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure Low (due to high molecular weight and relatively non - volatile nature)
Packing & Storage
Packing 100g of 2 - fluoro - 4 - iodobromobenzene packaged in a sealed glass bottle.
Storage Store 2 - fluoro - 4 - iodobromobenzene in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent leakage and exposure to air and moisture. Since it's a chemical, store it separately from incompatible substances like oxidizing agents and bases to avoid potential reactions.
Shipping 2 - fluoro - 4 - iodobromobenzene is shipped in specialized, sealed containers. It follows strict hazardous chemical shipping regulations, ensuring secure transit to prevent leakage and potential environmental or safety risks.
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2-fluoro-4-iodobromobenzene' 2-fluoro-4-iodobromobenzene' 2-fluoro-4-iodobromobenzene'
General Information
Frequently Asked Questions
What are the main uses of 2-fluoro-4-iodobromobenzene?
2-Fluoro-4-iodobromobenzene, which is a crucial intermediate in the field of organic synthesis, is widely used in medicine, pesticides and materials science.
In the field of medicine, it plays a key role. Due to the unique electronic and spatial effects of halogen atoms such as fluorine, iodine and bromine, the physicochemical properties and biological activities of compounds can be significantly changed. Using it as a starting material, complex molecular structures with specific pharmacological activities can be constructed through multi-step reactions. For example, when synthesizing some antibacterial drugs, the introduction of this intermediate can optimize the binding ability of the drug to the target, improve the antibacterial efficacy, and reduce the toxicity to normal human cells.
In the field of pesticides, 2-fluoro-4-iodobromobenzene is also indispensable. Through its participation in organic synthesis reactions, high-efficiency, low-toxicity and environmentally friendly pesticides can be prepared. Its halogen atoms can enhance the affinity of pesticide molecules to specific enzymes or receptors in pests or pathogens, enhance the insecticidal and bactericidal effects of pesticides, thereby reducing the amount of pesticides used and reducing the negative impact on the environment.
In the field of materials science, this intermediate also plays an important role. It can be used to synthesize functional materials, such as organic optoelectronic materials. By rationally designing the reaction path and introducing it into the conjugated system, the electronic transport properties and optical properties of the material can be regulated, laying the foundation for the preparation of high-performance organic Light Emitting Diodes (OLEDs), organic solar cells and other materials.
All in all, 2-fluoro-4-iodobromobenzene has shown great application value in many important fields due to its unique structure and reactivity, promoting technological development and innovation in related fields.
What are the physical properties of 2-fluoro-4-iodobromobenzene?
2-Fluoro-4-iodobromobenzene is one of the organic compounds. Its physical properties can be investigated.
First of all, its phase state, under normal temperature and pressure, is mostly liquid, but it may vary due to changes in environmental conditions. Looking at its color, it is often nearly colorless and transparent, but trace impurities exist, or the color is slightly different.
Its smell is difficult to determine, but organic halides often have a special smell. This substance may be irritating, so be careful when smelling.
As for the boiling point, due to the intermolecular force, its boiling point is quite high compared with similar compounds. The introduction of fluorine, iodine, and bromine atoms increases the intermolecular force, and more energy is required for gasification. However, the exact value must be accurately determined according to the experiment.
In terms of melting point, halogen atoms affect the regularity of molecular arrangement and intermolecular force, making the melting point different from benzene and its simple derivatives. Or due to the complex structure, the lattice arrangement is not easy, and the melting point is also a specific value.
Solubility is particularly important. This substance is insoluble in water, but it is non-polar or weakly polar, and the force between water molecules is weak. However, organic solvents such as carbon tetrachloride, dichloromethane, ether, etc. have good solubility. Due to the principle of "similar miscibility", such organic solvents are similar to the polarity of 2-fluoro-4-iodobromobenzene.
The density is related to its application. Due to the large atomic weight of halogen atoms, its density is greater than that of water. In chemical operations, this property can be used for separation and other steps. If mixed with water, it sinks underwater to separate phases.
To sum up, the physical properties of 2-fluoro-4-iodobromobenzene are of great significance in the fields of organic synthesis and chemical production. Researchers must investigate it carefully before making good use of this substance.
What is the chemical synthesis method of 2-fluoro-4-iodobromobenzene?
The chemical synthesis of 2-fluoro-4-iodobromobenzene is a key issue in the field of organic synthesis. The synthesis method needs to be based on the principles of organic chemistry and existing synthesis techniques, and the reaction steps can be skillfully designed to achieve.
To synthesize this compound, we can first focus on the order of introduction of the substituents on the benzene ring. Since different substituents have different effects on the activity of the benzene ring and subsequent reactions, the choice of order is extremely important. Common starting materials may be benzene derivatives containing specific substituents.
One possible strategy is to use bromobenzene as the starting material. First, fluorine atoms are introduced at specific positions of bromobenzene using electrophilic substitution reactions. In this process, a suitable fluorination reagent, such as a fluorine-containing electrophilic reagent, can be selected to selectively replace the hydrogen atom on the benzene ring under specific reaction conditions, such as specific temperatures, solvents and catalysts, to obtain a benzene derivative containing fluorine and bromine.
Then, an iodine atom is introduced at a specific position of the product. The reaction of introducing an iodine atom may be a nucleophilic substitution reaction or other suitable iodine substitution reactions. For example, in a suitable reaction system, a suitable iodine source and reaction conditions are selected to replace the hydrogen atom at a specific position on the benzene ring with an iodine atom, thereby obtaining the target product 2-fluoro-4-iodobromobenzene.
During the synthesis process, it is necessary to carefully control the conditions of each step of the reaction, such as temperature, reaction time, and the proportion of reactants, etc., to ensure the selectivity and yield of the reaction. At the same time, the separation and purification of the products in each step is also crucial. It is often necessary to use methods such as column chromatography and recrystallization to obtain high-purity intermediate products and final products, so that the synthesis process can proceed smoothly and achieve the purpose of synthesizing 2-fluoro-4-iodobromobenzene.
What are the precautions in storage and transportation of 2-fluoro-4-iodobromobenzene?
2-Fluoro-4-iodobromobenzene is an organic compound. During storage and transportation, many matters should be paid attention to to to ensure safety and avoid accidents.
Primary storage environment. This compound should be stored in a cool and ventilated warehouse, away from fires and heat sources. Because of its certain chemical activity, high temperature or open flame can easily cause dangerous reactions. The warehouse temperature should be strictly controlled, usually not exceeding 30 ° C, to prevent it from decomposing or volatilizing due to excessive temperature, causing concentration changes and increasing safety risks. And humidity must also be properly controlled. Too humid environment or cause it to deteriorate by moisture, affecting quality and stability.
Furthermore, ensure that the package is sealed when storing. Well packaged to avoid its contact with air, moisture, etc. 2-fluoro-4-iodobromobenzene in contact with water or moisture, or chemical reaction, or release harmful gases. Sealed packaging can also prevent its volatilization and escape, so as not to pollute the environment and keep the air in the warehouse clean.
This compound should also be stored separately from oxidants, acids, bases, etc., and must not be mixed. Because of its chemical activity, contact with these substances may cause severe chemical reactions, causing serious consequences such as fire and explosion. Such as oxidants or taking away their electrons, triggering oxidation reactions; acid-base or promoting its hydrolysis and other reactions increase the danger.
When transporting, it is necessary to ensure that the container does not leak, collapse, fall or damage. The handling process should be handled lightly to prevent severe vibration, impact and friction. Due to these conditions or damage to the packaging, 2-fluoro-4-iodobromobenzene may leak. And the vehicles used for transportation must be equipped with corresponding fire equipment and leakage emergency treatment equipment so that emergencies can be responded to in a timely manner.
During transportation, you should also follow the specified route and do not stop in residential areas and densely populated areas. Because if the compound leaks, it may pose a serious threat to the health of residents and the environment. Choosing a suitable transportation route can reduce the impact on people and the environment.
In short, the storage and transportation of 2-fluoro-4-iodobromobenzene must be handled with caution and in strict accordance with relevant regulations and standards to ensure the safety of personnel and the environment from pollution.
What is the market price range for 2-fluoro-4-iodobromobenzene?
In today's world, the market price of chemical substances often changes due to various reasons. It is difficult to determine the market price of a particular substance, such as 2-fluoro-4-iodobromobenzene.
First, the price of the raw material for producing this substance can change the price of 2-fluoro-4-iodobromobenzene. If the raw material is rare, the price of this substance must be high; if the raw material is abundant and cheap, the price may be slightly reduced.
Second, the method of preparing this chemical also affects its price. If the method is difficult and requires many steps, expensive tools and rare agents, the cost will be high, and the price will follow; if the method is simple and saves time and effort, the price may be reduced.
Third, the supply and demand of the city is the key to determining the price. If there are many people who use this product, the demand is greater than the supply, and the price will increase; if the supply exceeds the demand, the merchant may reduce the price in order to sell its goods.
Fourth, the stability of the current situation, the convenience of transportation, and the amount of taxation can all affect the price of 2-fluoro-4-iodobromobenzene. If the situation is turbulent and transportation is blocked, the cost will increase and the price will also rise; if the tax increases, the merchant will also turn it into a negative price.
Therefore, in order to know the market price of 2-fluoro-4-iodobromobenzene, it is necessary to check the price of raw materials, preparation methods, supply and demand conditions, and various related changes in real time to obtain a more accurate price. However, it is difficult to determine the range of the price.