2 Fluoro 6 Iodobenzoic Acid 98

2-Fluoro-6-iodobenzoic acid (2-fluoro-6-iodobenzoic acid), with a content of 98%, is widely used. It is often used as a key intermediate in the field of medicinal chemistry. Due to the unique structure of this compound, it has the characteristics of both fluorine and iodine atoms. Fluorine atoms have strong electronegativity, which can change the distribution of molecular electron clouds, enhance the stability and biological activity of compounds; iodine atoms are larger and can participate in a variety of chemical reactions, such as nucleophilic substitution, coupling reactions, etc., to help build complex drug molecular structures.
In the field of organic synthetic chemistry, this substance is also a common raw material. Through specific reactions, different functional groups can be introduced to expand the diversity of molecular structures for the preparation of new organic materials. For example, in the exploration of materials science, through the reaction of 2-fluoro-6-iodobenzoic acid, the synthesis of organic compounds with special photoelectric properties is expected to be applied in cutting-edge fields such as Light Emitting Diode and solar cells.
In addition, in fine chemical production, 2-fluoro-6-iodobenzoic acid can be used to prepare fine chemicals with special functions, such as high-performance dyes, pigments, etc. With its unique chemical properties, the products are endowed with excellent color performance and stability, meeting the strict requirements of high-end markets for fine chemical products. Overall, 2-fluoro-6-iodobenzoic acid plays an important role in many fields due to its unique structure and chemical properties, promoting the innovation and development of related industries.

I look at what you are asking, but I am inquiring about the price of 98% of 2-fluoro-6-iodobenzoic acid. However, the author of "Tiangong Kaiwu" remembers the origin of craftsmanship and products, and is not involved in the price of this chemical. And the price of this chemical often varies with changes in time, place, supply and demand. In the market, its price may vary due to the simple production method, the price of raw materials, and the amount of output.
To know the exact price, when you visit a commercial store of chemical raw materials, or ask a store specializing in this chemical. It may have different quotations due to the size of the batch. And the chemical market is changeable, and the price at that time may not be applicable to the present. Or you can look at the recent transaction price on the platform of chemical trading for reference. But this is only a temporary phenomenon and cannot be held together. It is difficult to determine the accurate price based on the method of this ancient book.

The preparation process of 2-fluoro-6-iodobenzoic acid (2-fluoro-6-iodobenzoic Acid) with a content of 98% is very complicated, and this is described in detail.
First, 2-fluorobenzoic acid is used as the starting material, which is the basis for preparation. In an appropriate reaction vessel, an appropriate amount of 2-fluorobenzoic acid is added, and then a specific organic solvent, such as dichloromethane, is added, which can make the reactants uniformly disperse and facilitate the reaction.
Then, the reaction system is cooled to a specific low temperature, generally between 0 ° C and 5 ° C. This low temperature environment can effectively control the reaction rate and avoid excessive side reactions. Subsequently, the source of iodine is slowly added, and the iodine element (I 2O) is often matched with an appropriate oxidant, such as a mixture of concentrated sulfuric acid and hydrogen peroxide. The function of the oxidant is to promote the conversion of the iodine element into the active iodine cation (I 🥰), and this active species can undergo electrophilic substitution reaction with the benzene ring of 2-fluorobenzoic acid.
During the reaction process, it is necessary to continuously stir to make the reactants fully contact. As the reaction proceeds, the iodine cation will selectively attack the 6-position carbon atom on the benzene ring of 2-fluorobenzoic acid. This selectivity is due to the adjacent localization effect of the fluorine atom, which makes the 6-position electron cloud density relatively high and more susceptible to electrophilic
After a period of reaction, monitor the progress of the reaction by thin layer chromatography (TLC) or high performance liquid chromatography (HPLC). When the reaction reaches the expected degree, that is, the raw material 2-fluorobenzoic acid is mostly converted into the target product 2-fluoro-6-iodobenzoic acid, the reaction is terminated.
After the reaction is terminated, the reaction mixture is poured into an appropriate amount of ice water to quench the unreacted oxidant and other active substances. Subsequently, the organic solvent is extracted, and the organic phase is combined after multiple extractions. The organic phase is washed with a saturated sodium bicarbonate solution and water in sequence to remove impurities.
The organic phase after washing is dried with an appropriate amount of anhydrous sodium sulfate or anhydrous magnesium sulfate to remove residual moisture. After that, the organic solvent is removed by reduced pressure distillation to obtain the crude product.
The crude product is purified by column chromatography or recrystallization. During column chromatography, a suitable silica gel is selected as the stationary phase, and a specific proportion of petroleum ether and ethyl acetate mixture is used as the mobile phase. Separation is achieved according to the difference in the distribution coefficient between the product and the impurities between the stationary phase and the mobile phase. Recrystallization selects an appropriate solvent, such as ethanol-water mixed solvent, so that the crude product is heated and dissolved, and then slowly cooled to precipitate pure 2-fluoro-6-iodobenzoic acid crystals. The purity can reach 98%.

2-Fluoro-6-iodobenzoic acid (2-fluoro-6-iodobenzoic Acid) contains 98%, and its storage conditions need to be treated with caution. This is a chemical substance, which is active or lively, and is susceptible to many factors.
First, the temperature should be stored in a cool place to avoid high temperature baking. Under high temperature, the thermal movement of its molecules intensifies, or chemical reactions can occur for no reason, resulting in damage to quality. Therefore, above room temperature, such as in the hot summer sun, it must not be stored.
Times and humidity, moisture are easy to cause deliquescence and other changes. If in a humid place, water vapor adheres to it, or dissolves or miscibles with impurities, reducing the purity and changing the nature. When placed in a dry place, such as a storage cabinet with a desiccant, to prevent moisture from invading.
Furthermore, light is also the key. Many chemicals will react photochemically when exposed to light, and this product is no exception. Direct exposure to strong light, or changes in molecular structure. It should be stored in an opaque container and placed in a dark place to avoid light intrusion.
In addition, this substance may be corrosive and toxic, and must be isolated from other substances when stored. Do not store with easily reactive substances, such as alkalis, the two meet or react violently, causing danger. It should be placed in a separate place and clearly marked to show its characteristics, so that it can be used and supervised with caution.
In addition, the storage place should be well ventilated. If harmful gases accumulate, not only will the substance itself be damaged, but also the safety of people will be seriously endangered. Good ventilation can drive away volatile gases and ensure environmental safety. In short, careful and thorough storage can ensure the quality and safety of 2-fluoro-6-iodobenzoic acid.

2-Fluoro-6-iodobenzoic acid, with a content of 98%, its Quality Standard is quite critical, which is related to many characteristics of this compound.
First of all, in appearance, it should appear as a white to off-white crystalline powder with uniform texture and no impurities visible to the naked eye. This pure color and state lays the foundation for its subsequent application. The presence or absence of impurities has a huge impact, due to impurities or changes in its chemical activity and reaction path.
Regarding the melting point, it needs to be within a specific range, about [specific melting point range]. The melting point is the inherent property of the substance. If it deviates from this range, it may suggest poor purity or crystal form variation, which will affect its stability and reactivity.
The purity is based on 98% and is accurately determined by high performance liquid chromatography (HPLC). This high purity ensures that it participates in various reactions with stable chemical properties and reduces side reactions. The remaining 2% impurities need to be accurately analyzed for their type and content. Because they may be synthetic by-products and raw material residues, different impurities have different effects on product performance.
The moisture content also has strict requirements and should be lower than [specific moisture content]. Excessive moisture may cause hydrolysis of compounds, change chemical structure, and affect quality and shelf life.
In addition, the content of heavy metals must be strictly controlled, such as lead, mercury, cadmium, etc., and must not exceed [very low standard content]. Heavy metal residues not only affect the chemical properties of products, but also threaten human health in pharmaceutical and food-related applications.
Such Quality Standards ensure that 2-fluoro-6-iodobenzoic acid can play a stable and reliable role in scientific research, medicine, chemical synthesis and other fields, providing a solid material foundation for the development of various industries.