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What are 97% of the physical properties of 2-fluoro-6-iodobenzoyl Chloride?
2-Fluoro-6-iodobenzoyl chloride, with a content of 97%. The physical properties of this substance are particularly important and relevant to its many applications. Its properties are colorless to light yellow liquid with a strong pungent odor. Looking at its color and state can really help the preliminary identification.
The boiling point is the key temperature for the gasification of the substance. The boiling point of 2-fluoro-6-iodobenzoyl chloride is quite high. Due to the strong intermolecular force, it takes more energy to make the molecule break free and turn into a gaseous state. Therefore, the boiling point is in a specific range, but it may fluctuate slightly due to impurities and other factors.
The melting point is also an important physical property. The melting point of this compound is affected by the molecular structure and interaction. At a specific temperature, the solid-liquid state changes, and this temperature is its melting point.
In terms of density, it is heavier than water. When placed in water, it will sink to the bottom. This is due to the close arrangement of its molecules and the large mass per unit volume.
Solubility is also a key consideration. It has good solubility in organic solvents, such as common ether, dichloromethane, etc. Due to the principle of similar miscibility, its molecular structure is similar to that of organic solvents, so it can be miscible. However, in water, because of its weak interaction with water molecules, its solubility is not good.
In terms of volatility, although it is not very volatile, it will evaporate slowly under normal temperature because of its certain vapor pressure. This characteristic requires special attention during storage and use.
The physical properties of 2-fluoro-6-iodobenzoyl chloride are of great significance in many fields such as chemical synthesis and drug development. Practitioners need to understand in detail in order to make good use of this substance.
What are the main uses of 2-fluoro-6-iodobenzoyl Chloride 97%?
2-Fluoro-6-iodobenzoyl chloride, with a content of 97%, is widely used. In the field of pharmaceutical synthesis, it is often used as a key intermediate. For example, when developing specific targeted anti-cancer drugs, with its unique chemical structure, it can precisely react with other compounds to construct molecular structures with specific pharmacological activities, helping to achieve precise inhibition of cancer cell growth and proliferation.
In the field of materials science, it can participate in the preparation of new polymer materials. After polymerization with monomers containing specific functional groups, polymer materials are endowed with unique properties, such as enhancing the chemical resistance of materials or optimizing their optical properties, so as to meet the special requirements of material properties in different fields such as electronic devices and optical lenses.
In the production of fine chemicals, 2-fluoro-6-iodobenzoyl chloride is also an important raw material. It is used to synthesize fine chemicals such as high-end coatings, fragrances and additives. In the preparation of coatings, it can improve the adhesion, durability and product quality of coatings; in the synthesis of fragrances, its participation in the reaction can generate unique aroma components and enrich the fragrance category.
In addition, in the research and development of pesticides, it can be used as a key starting material for the synthesis of high-efficiency and low-toxicity pesticides. Through rational molecular design and reaction, new pesticides that can effectively control pests and diseases and are environmentally friendly can be created. Overall, 2-fluoro-6-iodobenzoyl chloride plays an indispensable role in many important fields, and is of great significance to promoting technological progress and product upgrading in related industries.
2-fluoro-6-iodobenzoyl of Chloride 97%
2-Fluoro-6-iodobenzoyl chloride, with a content of 97%, the synthesis method is slightly as follows.
First, the corresponding 2-fluoro-6-iodobenzoic acid is used as the starting material and interacts with the chlorination reagent. The commonly used chlorination reagent is sulfinyl chloride (SOCl ²). The two are mixed, and under suitable reaction conditions, such as heating and supplemented by an appropriate catalyst, the carboxyl group of benzoic acid reacts with sulfinyl chloride. 2-Fluoro-6-iodobenzoyl chloride is obtained by substituting the hydroxyl group of the carboxyl group with the chlorine atom in the thionyl chloride, and escaping sulfur dioxide (SO _ 2) and hydrogen chloride (HCl) gases. When the reaction temperature should be controlled in a moderate range. If it is too low, the reaction will be slow, and if it is too high, it may lead to side reactions. Generally, the reflux temperature is appropriate.
In addition, oxalyl chloride ((COCl) -2) can also be used instead of thionyl chloride as a chlorination reagent. 2-Fluoro-6-iodobenzoic acid reacts with oxalyl chloride in inert solvents such as dichloromethane, or in the presence of catalytic amounts of N, N-dimethylformamide (DMF). Oxalyl chloride has high activity and the reaction is easy to occur. During the process, 2-fluoro-6-iodobenzoyl chloride is formed, and carbon dioxide (CO 2), carbon monoxide (CO) and hydrogen chloride (HCl) are released at the same time. This reaction condition is relatively mild, which is conducive to operation and control.
Another phosphorus trichloride (PCl
) is used as a chlorination agent. 2-fluoro-6-iodobenzoic acid is mixed with phosphorus trichloride in a certain proportion and reacted in a suitable reaction vessel. The phosphorus atom of phosphorus trichloride nucleophilically attacks the carbonyl carbon of the carboxyl group. After a series of transformations, the target product 2-fluoro-6-iodobenzoyl chloride is finally generated, and phosphoric acid (H 🥰 PO 🥰) is obtained at the same time. However, the post-processing of this method is relatively complicated, and it is necessary to properly separate the product and phosphoric acid.
All these synthesis methods have their own advantages and disadvantages, and they need to be used according to actual needs, such as the availability of raw materials, cost, and purity requirements of the product.
2-fluoro-6-iodobenzoyl Chloride 97% What to watch out for when storing
2-Fluoro-6-iodobenzoyl chloride, the content is 97%. When storing this material, many matters should be paid attention to. It is active, highly corrosive and reactive, so the storage environment is the key.
First temperature and humidity. It should be placed in a cool, dry place, away from heat sources and moisture. High temperature can easily cause its volatilization to intensify, and high humidity may cause adverse reactions such as hydrolysis, which will damage its quality. The warehouse temperature should be controlled between 15 ° C and 25 ° C, and the humidity should be maintained at 40% - 60%.
The second time is to avoid light. The substance is sensitive to light, and light may cause it to undergo photochemical reactions, resulting in deterioration. Therefore, it should be stored in a dark container such as a brown bottle and stored in a dark place.
Furthermore, attention should be paid to isolation from other substances. Due to its corrosive and reactive nature, it should not be co-located with alkalis, alcohols, water and other substances that are easy to react with. It should be stored separately in a specific area, and the area should be clearly marked with warning signs.
In addition, the storage area should be well ventilated. Good ventilation can disperse harmful gases that may evaporate in time and reduce safety risks. At the same time, the sealing condition of the container should be checked regularly. If there is any leakage, proper measures should be taken in time to prevent the harm from expanding. During handling and storage, operators must take good protection, wearing protective clothing, protective gloves and goggles, etc., to avoid contact and cause injury. In this way, the safety and quality of 2-fluoro-6-iodobenzoyl chloride are guaranteed during storage.
2-fluoro-6-iodobenzoyl about 97% of the market price for Chloride
I look at your question, but I am inquiring about the market price of 97% of 2-fluoro-6-iodobenzoyl chloride. However, the price of this chemical often changes for many reasons, and it is difficult to determine an exact value.
First, the trend of supply and demand has a great impact. If there is strong demand for this product in the market and the supply is limited, the price may increase; conversely, if the supply exceeds the demand, the price will decrease.
Second, the amount of purchase is also related to the price. If you buy in bulk, the merchant may give a lower price due to a large quantity discount; if you only buy a small amount, the price may be relatively high.
Third, the source of origin also has an impact. Different places of origin may have different prices due to differences in production costs, transportation costs, etc.
Fourth, the state of market competition cannot be ignored. If there are many merchants operating this chemical in the market, the competition is fierce, and the competition is for customers, or there is a price reduction; if there are few merchants and the competition is small, the price may be maintained high.
As mentioned in "Tiangong Kaiwu", the prices of various products are subject to various restrictions. Although it is difficult for me to state the exact market price of 2-fluoro-6-iodobenzoyl chloride at 97%, if you want to know the price, you can consult chemical product suppliers, distributors, or refer to the quotations of chemical product trading platforms, so that relatively accurate price information may be available.