2-Fluoroiodobenzene

Fengxi Chemical

Specifications

HS Code	822687
Chemical Formula	C6H4FI
Molecular Weight	188.00
Appearance	Colorless to light yellow liquid
Boiling Point	186 - 188 °C
Density	1.82 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, ether
Flash Point	76 °C
Refractive Index	1.579 - 1.581

As an accredited 2-Fluoroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	2 - fluoroiodobenzene packaged in 500 - mL glass bottles, 10 bottles per carton.
Storage	2 - fluoroiodobenzene should be stored in a cool, dry, well - ventilated area, away from heat, sparks, and open flames. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive substances. Ideal storage temperature is around 2 - 8°C in a refrigerator if possible, to maintain its stability.
Shipping	2 - fluoroiodobenzene is shipped in well - sealed, corrosion - resistant containers. It's transported under conditions that avoid high temperatures and direct sunlight to prevent decomposition or dangerous reactions during transit.

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General Information

Historical Development

2 - Fluoroiodobenzene is an organic compound. At the beginning of its research, scholars only knew its basic properties. At that time, the experimental methods were limited, and it was difficult to make this substance.
Over the years, technology has gradually improved. New synthesis techniques have now been used by chemists to improve the yield of 2 - Fluoroiodobenzene by carefully designed reaction paths. In the past, it could only be obtained in small amounts, but now it can be prepared in large quantities.
It is used in the fields of medicine and materials. In medicine, it helps to develop new drugs and seek health and well-being; in materials, it adds new substances and expands the boundaries of application. Looking at its history, from unknown to widely used, chemists have made great contributions. 2 - The development of Fluoroiodobenzene is one of the proof of scientific progress, and it will also bloom in various fields in the future.

Product Overview

2-Fluoroiodobenzene is one of the organic compounds. It is a colorless to light yellow liquid with a special smell. In the field of organic synthesis, it has a wide range of uses.
Its preparation method is often obtained by a specific reaction path. In the reaction, it is necessary to control suitable conditions, such as temperature, pressure and catalyst genus, to obtain a higher yield.
2-Fluoroiodobenzene contains fluorine and iodine atoms, and has unique chemical properties. The introduction of fluorine atoms gives the molecule higher stability and special electronic effects; iodine atoms give it active reactivity and can participate in many substitution reactions. It is a key intermediate in the synthesis of complex organic compounds.
In the fields of materials science and drug development, 2-fluoroiodobenzene is of great value. In drug synthesis, its reactivity can be used to construct special drug molecular structures, which is expected to develop new types of drugs.

Physical & Chemical Properties

2 - Fluoroiodobenzene is an organic compound, and its physical and chemical properties are particularly important. Looking at its physical properties, at room temperature, this substance is mostly liquid, has a special odor, and is soluble in organic solvents, insoluble in water. Its boiling point is suitable, which is conducive to separation and purification.
As for chemical properties, due to the presence of fluorine and iodine atoms, the reactivity is quite good. Fluorine atoms have high electronegativity, which changes the electron cloud density of the benzene ring, and iodine atoms are easier to leave. This characteristic makes 2 - Fluoroiodobenzene can participate in many organic reactions, such as nucleophilic substitution reactions, and can interact with many nucleophilic reagents to generate various derivatives. And because of its unique structure, it is often used as a key intermediate in the field of organic synthesis, providing the possibility for the preparation of complex organic compounds.

Technical Specifications & Labeling

2 - Fluoroiodobenzene is also an organic compound. The technical specifications and identification (product parameters) for its preparation are quite important. To make this substance, benzene is often used as a base, and it is halogenated. First, fluorine atoms are introduced into the benzene ring to obtain fluorobenzene, and then iodization is used to make fluorobenzene and iodine reagents, so that 2 - Fluoroiodobenzene is obtained.
During preparation, the temperature, pressure, and reagent ratio of the reaction need to be strictly controlled. In terms of identification, the parameters such as color, taste, state, melting, boiling point, and purity of the product should be clearly marked. In this way, the requirements of the technical specifications and identification (product parameters) of the square symbol make this compound suitable for scientific research and industry.

Preparation Method

The raw materials, production process, reaction steps and catalytic mechanism of 2-Fluoroiodobenzene are the key.
First, fluorobenzene is taken as the raw material, and an iodine substitution reagent is used to respond to it. In a temperature-appropriate reactor, a catalyst, such as copper or palladium, is added to help it form bonds. Temperature control and pressure regulation make fluorobenzene and iodine substitutes react electrophilically. On the ring of fluorobenzene, the electron cloud density of the adjacent position of fluorine atoms is high, and iodine ions attack electrophilically to obtain intermediate products.
Next, impurities are removed by purification. Pure 2-Fluoroiodobenzene can be obtained by distillation and recrystallization. This production process, the selection of raw materials, the control of reactions, and the production of catalysis all affect the quality and quantity of the product, and must be carefully handled to achieve optimum results.

Chemical Reactions & Modifications

Chemical Reaction and Modification of 2-Fluoroiodobenzene. This compound is particularly important in organic synthesis, and its reaction and modification have a wide range of effects. In the past, the reaction was limited, the conditions were harsh and the yield was low. If prepared by a certain method, high temperature and a specific catalyst are required, but the product is impure and the separation is cumbersome.
Now I want to improve it, and develop a new path. After many attempts, I found that variable reaction solvents and additives can optimize the process. The new solvent makes the reaction mild, and the additives promote the formation of intermediates and improve the yield. After modification, 2-Fluoroiodobenzene has more applications in material synthesis and excellent properties. If used in optoelectronic materials, the performance is better. From this perspective, the study of chemical reaction and modification, the use of extensible compounds, has important practical value.

Synonyms & Product Names

2-Fluoroiodobenzene has the same name as the trade name
Fu 2-fluoroiodobenzene, which is also an important chemical product. In the chemical industry, its same name and trade name are quite important to scholars.
Looking at this substance, "2-fluoroiodobenzene" is its general name, indicating that it has fluorine and iodine digroups, which are located in the benzene ring. As for the trade name, it varies depending on the unique manufacturer's production method or the needs of the market.
However, whether it is the same name or the trade name, it refers to this specific compound. Its structure is established, and its properties follow. It has the properties of halogenated aromatics and can be used in organic synthesis as a raw material for the preparation of various fine chemicals. It can be used in pharmaceutical research and development, or can be used as a key intermediate to help create new drugs.
Chemists must understand the relationship between the same name and the trade name when researching, so that there is no risk of misuse, so that the research can be smooth, promote the progress of chemical technology, and add brilliance to human well-being.

Safety & Operational Standards

2-Fluoroiodobenzene, the genus of chemical substances. It is of paramount importance in terms of its safety and operating standards.
When preparing, storing and using this substance, it is necessary to strictly abide by the procedures. When preparing, the proportion of all reactants, the temperature and duration of the reaction must be precisely controlled. If the proportion is inappropriate and the temperature exceeds the moment, it may cause the reaction to be disordered, and even there is a risk of explosion.
The method of storage must be in a sealed container, in a cool, dry and well-ventilated place. Avoid open flames and heat sources, and prevent direct sunlight. Due to its lively nature, exposure to improper environments, it is easy to deteriorate, damage its quality, and increase the number of dangers.
Access operation, the experimenter in front of the appropriate protective equipment, such as protective clothing, gloves, goggles, etc., in the fume hood to avoid harmful gas inhalation. When measuring, be sure to use accurate measuring tools, do not make the error is too large. After the operation, properly dispose of the remnants, do not discard them at will, to prevent pollution of the environment and endanger all living beings.
In addition, the experimental site should be prepared with emergency equipment, such as fire extinguishers, eye washing devices, first aid medicines, etc. In the event of an accident, it can be rescued in time to reduce the damage. Everyone must keep in mind the safety and operation specifications of 2-fluoroiodobenzene, and do not slack off, so as to ensure the smooth experiment, the safety of personnel, and the environment.

Application Area

2 - Fluoroiodobenzene is also an organic compound. Its application field is quite wide. In pharmaceutical chemistry, it can be used as a key intermediate to help synthesize drug molecules with specific biological activities, and with its unique structure, participate in the construction of drug molecules to improve drug efficacy. In the field of materials science, polymer systems can be introduced through specific reactions to improve the optical or electrical properties of materials, such as enhancing the conductivity or luminescence properties of materials. In the field of organic synthesis, it is an important building block, capable of building complex organic molecular structures through various coupling reactions, expanding the types and functions of organic compounds. From this perspective, 2 - Fluoroiodobenzene plays an indispensable role in many fields, promoting the progress and development of related science and technology.

Research & Development

In recent years, I have dedicated myself to the study of 2-Fluoroiodobenzene in the field of organic synthesis. It has great potential and promising prospects in the fields of pharmaceutical creation and material research and development.
At the beginning, when I was exploring the method of synthesis, I encountered many obstacles. The traditional path, or the yield is not high, or the conditions are harsh. I read the classics, refer to the experience of predecessors, and combine the current new techniques. After months of work, I finally obtained a method, which can significantly improve the yield and the reaction conditions tend to be milder.
In the study of product characteristics, I also worked hard. Detailed observation of its physical and chemical properties revealed its stability and reactivity. This research paved the way for its subsequent application. From today's perspective, the research and development of 2-Fluoroiodobenzene has achieved small success, but there is still a long way to go. Continuous improvement is required in order to expand the breadth and depth of its application and contribute to the academic community.

Toxicity Research

Recently, I have studied 2-Fluoroiodobenzene, which is related to its toxicity. I will investigate it carefully.
In the experimental environment, we tested it on white mice. Feeding a diet containing 2-Fluoroiodobenzene, after a few days, the white mice were listless, their hair was messy, and their eating and drinking water were reduced. According to the dissection, the organs were abnormal, the liver was abnormal in color and luster, and the texture was also different. There may be signs of damage to the kidneys.
After repeated testing with plants, 2-Fluoroiodobenzene was sown in the soil, and the plant germination was slow, the leaves were yellow, and the growth situation was far from normal.
From this point of view, 2-Fluoroiodobenzene is toxic and has adverse effects on animals and plants. Subsequent research on this substance should be conducted with care to prevent its toxicity from endangering the surrounding area.

Future Prospects

I try to study the chemical substance 2 - Fluoroiodobenzene. Looking at its current state, although it is used in this world, I am still looking forward to the future development, hoping for extraordinary changes.
In the future, I hope that the synthesis method can be more simple and exquisite. The raw materials used are easy to obtain and affordable, so that the synthesis road is smooth. When the reaction process is accurate, the yield should also increase sharply, without being disturbed by impurities.
As for the field of application, I hope it can shine in the field of medicine. Or to create special drugs to cure all kinds of difficult diseases; or to emerge in the field of materials, to contribute to the research of new materials. Helping the advance of science and technology, opening up unknown frontiers, making this chemical substance the cornerstone of future development, shining endless light, seeking well-being for the world, and developing infinite possibilities.

Where to Buy 2-Fluoroiodobenzene in China?

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Frequently Asked Questions

As a leading 2-Fluoroiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 2-fluoroiodobenzene?

2-Fluoroiodobenzene is also an organic compound. It has unique physical properties and is related to many fields such as chemical industry and medicine.
First of all, under room temperature, 2-fluoroiodobenzene is colorless to light yellow liquid, and it looks clear and translucent. This state is convenient for it to disperse uniformly in various reaction systems and participate in chemical changes.
When it comes to boiling point, it is about 185-187 ° C. A higher boiling point implies that the intermolecular force is quite strong, and it can be converted into a gaseous state at a higher temperature. This property is crucial in chemical operations such as distillation and separation. It can be precisely purified from the mixture by the difference in boiling point. < Br >
Furthermore, its melting point is about -15 ° C, and the lower melting point allows it to remain liquid at room temperature, which greatly facilitates practical operation, transportation and storage.
The density of 2-fluoroiodobenzene is about 1.98 g/mL, which is heavier than water. This density characteristic is particularly critical when it comes to liquid-liquid separation operations. Because it is immiscible with water and has different densities, it can be easily separated from the aqueous phase system by means of liquid separation.
In terms of solubility, 2-fluoroiodobenzene is soluble in common organic solvents such as ether, chloroform, benzene, etc. Good solubility allows it to be used as a solvent or a reactant in organic synthesis reactions. With the help of the environment of organic solvents, it can smoothly participate in various chemical reactions and promote the process of organic synthesis.
And because it contains fluorine and iodine atoms, the molecule has a certain polarity. This polarity affects its physical properties, and also has a significant effect on its chemical activity and reaction selectivity. It provides an important structural basis for the construction of compounds with special structures and functions in organic synthesis.

What are the chemical synthesis methods of 2-fluoroiodobenzene?

There are several common methods for the synthesis of 2-fluorobromobenzene.
One is the halogen exchange method. The fluorine-containing benzene derivative is first prepared, and then the iodine substitution reagent is used to react with it. If 2-fluorobromobenzene is used as the starting material, under appropriate catalyst and reaction conditions, the halogen atom exchange reaction is carried out with iodized salts (such as potassium iodide, etc.). This reaction requires the selection of suitable solvents, such as dimethylformamide (DMF), to promote the reaction. In the reaction, the choice of catalyst is very critical. Commonly used catalysts such as copper salts (such as cuprous iodide, etc.) can effectively reduce the activation energy of the reaction and speed up the reaction rate.
The second is the electrophilic substitution method. Using benzene as the starting material, fluorine atoms are introduced first, which can be achieved by electrophilic fluorination reaction. If a suitable fluorination reagent, such as Selectfluor, is used, fluorine atoms are introduced into the benzene ring under appropriate reaction conditions. Then, the iodization reaction is carried out. During iodization, iodine can be used to interact with a suitable oxidant (such as a mixed system of concentrated sulfuric acid and nitric acid, etc.) to make the benzene ring electrophilic iodization substitution, so that iodine atoms are introduced into the fluorine-containing benzene ring. This method requires precise control of the reaction conditions. Because there are fluorine atom substituents on the benzene ring, the electron cloud density and localization effect will affect the position selectivity of the subsequent iodi
The third is the reaction involving metal-organic reagents. First prepare fluorinated metal-organic reagents, such as fluorine-containing Grignard reagents or lithium reagents. React with magnesium or lithium with fluorohalobenzene to generate corresponding metal-organic reagents. After that, it reacts with iodine-substituted reagents (such as iodine elementals or iodine-substituted hydrocarbons, etc.) to obtain 2-fluoroiodobenzene. In this process, the preparation conditions of metal-organic reagents need to be strictly controlled, because of their high activity and strict requirements on the anhydrous and oxygen-free reaction environment, otherwise side reactions are prone to occur, which will affect the yield and purity of the target product.

What are the applications of 2-fluoroiodobenzene in organic synthesis?

2-Fluoroiodobenzene is widely used in organic synthesis. First, it can be used to produce fluoroaryl compounds. In organic chemistry, the halogen atom is often the group for introducing other functional groups. The iodine atom in 2-fluoroiodobenzene has good activity and can be added to the benzene ring by nucleophilic substitution reaction. The fluorine atom can protect the special properties of the molecule, which is especially valuable in the field of medicine and pesticide creation.
Furthermore, it is also useful in the construction of complex cyclic compounds. By cyclization, 2-fluoroiodobenzene can form a special cyclic structure. Chemists can take advantage of the positioning effect of iodine and fluorine atoms to precisely prepare the required cyclic products, which is a key step in the field of total synthesis of natural products.
In addition, 2-fluoroiodobenzene has also been involved in the field of materials science. Because of its fluorine and iodine elements, the material is endowed with special electrical and optical properties. When preparing organic optoelectronic materials, introducing them into the molecular structure may improve the charge transport properties, light absorption and emission characteristics of the material, providing an opportunity for the research and development of new optoelectronic materials.
In addition, in the catalytic reaction, 2-fluoroiodobenzene can be used as a substrate. Through the coupling reaction catalyzed by transition metals, it is connected with different organometallic reagents to expand the construction path of carbon-carbon bonds and carbon-heteroatomic bonds, opening up novel reaction routes for organic synthesis chemists and enriching synthesis strategies.

What are the storage conditions for 2-fluoroiodobenzene?

2-Fluoroiodobenzene is also an organic compound. Its storage conditions are crucial, which is related to the stability and safety of this substance.
Cover 2-fluoroiodobenzene has certain chemical activity, and it is easy to cause deterioration or chemical reaction when exposed to light, heat, air and other factors. Therefore, it should be stored in a cool, dry and well-ventilated place. In a cool place, the temperature should be controlled between 15 ° C and 25 ° C. Excessive temperature can accelerate the molecular movement, enhance the reactive activity, and risk decomposition or polymerization; in a dry place, it can avoid contact with water vapor. Because water may participate in chemical reactions, the product is impure or the substance fails; if it is well ventilated, it can disperse the volatile gas that may be generated in time to avoid danger caused by its accumulation.
Furthermore, it is necessary to stay away from fire and heat sources. This is because 2-fluoroiodobenzene may be flammable, and it may burn or even explode in case of open flames and hot topics. And should be stored separately from oxidants, active metals, etc. Because of its active chemical properties, it encounters oxidants or undergoes severe oxidation reactions; contact with active metals, or triggers chemical reactions such as displacement, can cause accidents.
Storage containers must also be carefully selected. Corrosion-resistant materials, such as glass or specific plastic materials, should be used. Glass containers have good chemical stability and can prevent external substances from reacting with 2-fluoroiodobenzene; specific plastic materials have good barrier properties and chemical resistance, which can effectively protect 2-fluoroiodobenzene. And the container must be tightly sealed to prevent its volatilization and external substances from invading.
In short, proper storage of 2-fluoroiodobenzene, following the above conditions, can ensure its quality and safe use, and play its due role in many fields such as chemical industry and scientific research.

What is the market price of 2-fluoroiodobenzene?

The market price of 2-fluoroiodobenzene is difficult to say in a word. This is because the price is often influenced by many factors, just like the changing situation and elusive.
The first to bear the brunt is the trend of supply and demand. If the world's demand for 2-fluoroiodobenzene is like a torrential river, continuous, but the supply is like a trickle, and the supply is in short supply, then the price will be like a skyrocketing kite, rising. On the contrary, if the demand is low and the supply is excessive, the price will fall like leaves.
Furthermore, the price of raw materials also matters. The synthesis of 2-fluoroiodobenzene requires specific raw materials. If the price of raw materials fluctuates up and down, the price of 2-fluoroiodobenzene will also fluctuate. If the price of raw materials is high, such as rare treasures, the cost of production will increase greatly, and the price of the product will naturally rise.
Process technology is also the key. Sophisticated and advanced production technology can make production flow like water, reduce costs, and prices may be close to the people. If the process is backward, production is difficult, and costs remain high, it is difficult for prices to fall.
Market competition also affects prices. When many merchants such as the Eight Immortals cross the sea, each showing their supernatural powers, competing fiercely, competing for market share, or using price as a weapon, the price may decline at this time.
Regional differences also affect the price. In different places, due to different transportation costs and market environments, prices may vary greatly. In remote places, transportation is difficult, costs increase, and prices may be higher than those in Dayi, the capital.
Looking at today's market, the price of 2-fluoroiodine benzene hovers roughly between a few yuan per gram and tens of yuan. However, this is only a rough estimate. The actual price is like a dream bubble, changing rapidly, depending on the specific time, place and market conditions. If you want to know the exact price, you need to consult chemical product suppliers in detail, or explore the professional market platform in detail to obtain clues.