2 Hydroxy 3 Iodopyridine
Iodobenzene

2-Hydroxy-3-Iodopyridine

Fengxi Chemical

    Specifications

    HS Code

    991520

    Name 2 - Hydroxy - 3 - Iodopyridine
    Molecular Formula C5H4INO
    Molecular Weight 219.00
    Appearance Solid (usually white to off - white)
    Cas Number 21345 - 46 - 2
    Melting Point 162 - 164 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in polar organic solvents like DMSO, DMF
    Pka Around 3.8 (approximate value for the phenolic - OH group)
    Stability Sensitive to light and air, may oxidize over time
    Chemical Formula C5H4INO2
    Molecular Weight 221.00
    Appearance Solid (presumed, as no data on specific appearance given but common for such organic compounds)
    Melting Point No data
    Boiling Point No data
    Solubility In Water No data
    Solubility In Organic Solvents No data
    Density No data
    Pka No data
    Stability Should be stored properly away from strong oxidizing agents (general assumption for organic compounds with such functional groups)
    Chemical Formula C5H4INO
    Molecular Weight 205.00
    Appearance Solid
    Color Off - white to light yellow
    Odor Odorless
    Melting Point 167 - 171 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like DMSO, DMF
    Pka 3.69 (approximate value for pyridinium ion)

    As an accredited 2-Hydroxy-3-Iodopyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 2 - hydroxy - 3 - iodopyridine in a sealed, chemical - resistant plastic bottle.
    Storage 2 - Hydroxy - 3 - iodopyridine should be stored in a cool, dry place away from direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and contact with air, which could potentially lead to degradation. Store it separately from incompatible substances, such as strong oxidizing agents. Ensure the storage area is well - ventilated to minimize the risk of vapor buildup.
    Shipping 2 - hydroxy - 3 - iodopyridine, a chemical, is shipped in sealed, corrosion - resistant containers. It adheres to strict chemical shipping regulations. Special handling ensures safety during transit to prevent any leakage or damage.
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    2-Hydroxy-3-Iodopyridine
    General Information
    Historical Development
    Those who have studied chemistry in ancient times have dedicated themselves to the study of substances, and 2-Hydroxy-3-Iodopyridine is also the one who has been injected into it. At the beginning, the research was rare, and the nature and use of it were not known in detail. However, the sages worked tirelessly, and over the years, the quality gradually became clear.
    Beginning to seek it in a simple way, although obtained, the quantity is small and the quality is not pure. Later craftsmen studied new techniques and improved the process, and the yield increased and the quality became better. In the field of medicine, it gradually showed its ability and helped to cure diseases. And in other industries, such as the system of materials, it also developed its use.
    Looking at the path of its development, it has been little known to a wide range of people, and it really depends on the wisdom and diligence of all scholars. Today, it has occupied an important position in the industry, contributing to the prosperity of the chemical industry, and future generations should also follow the previous industry, making it more widely used and more great.
    Product Overview
    2-Hydroxy-3-Iodopyridine is the chemical that I have dedicated myself to studying. Its shape is in the shape of powder, and its color is as white as snow. Looking at its structure, on the pyridine ring, the two hydroxyl groups are stable, and the three iodine atoms are dependent on each other. This unique structure gives it a different kind of property.
    Its physicochemical properties are quite stable at room temperature. In case of strong heat, strong acid or strong base, it reacts and changes unpredictably. And it is slightly soluble in organic solvents and can be used as a medium for various reactions.
    When it comes to uses, in the field of pharmaceutical synthesis, this product can be called a key raw material. With ingenious craftsmanship, it can make special drugs, cure diseases and benefit the world. In the field of organic synthesis, it is also an important building block for chemists to build complex molecules and explore unknown environments. It is an indispensable treasure for chemical research and industrial applications.
    Physical & Chemical Properties
    2 - Hydroxy - 3 - Iodopyridine is a unique chemical substance. Its physical properties are unique. Looking at it, it is in a crystalline state at room temperature, with a nearly pure white color, a fine powder, and a delicate touch. Its melting point is about a specific range. When heated to this temperature, it gradually melts into a liquid state, which is an important characteristic of its physical state transformation.
    In terms of chemical properties, this substance has certain reactivity. Under specific reaction conditions, both hydroxyl groups and iodine atoms can participate in many chemical reactions. In case of nucleophiles, iodine atoms are easily replaced and other compounds are derived. Its hydroxyl groups can also undergo esterification and other reactions in a suitable acid-base environment, showing rich chemical changes. From this perspective, 2-Hydroxy-3-Iodopyridine has considerable value in exploration and application in the field of chemical research, and can provide a key foundation for the creation of new compounds.
    Technical Specifications & Labeling
    There is a product today, the name is 2 - Hydroxy - 3 - Iodopyridine. Study its technical specifications and identification (product parameters), and those who are related to this product must clarify its regulations.
    If you want to make this product, the skill should come first. The raw materials must be carefully selected and the proportions are accurate. The temperature, time and pressure of the reaction are all key. If the temperature of the reaction is too high, the quality will change, and if it is too low, the effect will not be reached. When it is stable to an appropriate degree.
    In terms of labeling, the product parameters must be detailed. The ingredients contained, the geometry of purity, should be clearly marked. On the packaging, there should also be clear instructions to inform everyone of the nature, use and storage of this product. In this way, the product can be made in accordance with technical specifications, with correct identification, and can be trusted by users.
    Preparation Method
    In order to prepare 2 - Hydroxy - 3 - Iodopyridine, the method of preparation is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials should be careful, and it should be suitable for its characteristics. The production process must be refined to ensure that the reaction is smooth.
    The reaction steps, first, take a suitable starting material and put it in a special vessel according to a certain proportion. Next, adjust the temperature to the appropriate degree, apply catalysis to make it respond. This catalytic mechanism is essential, and a suitable catalyst needs to be selected to promote the reaction speed and yield.
    During operation, it is advisable to observe the reaction state carefully and fine-tune the conditions according to the situation. In this way, it is possible to obtain a pure 2-Hydroxy-3-Iodopyridine to meet the needs of scientific research.
    Chemical Reactions & Modifications
    Taste the wonders of chemistry, with all kinds of changes, related to the transformation of substances and the change of properties. Today there is 2-Hydroxy-3-Iodopyridine, and its chemical reaction and modification are worth exploring.
    In the process of reaction, the interaction between it and various reagents can be observed. Or in case of nucleophilic reagents, the iodine of halogens is easily replaced by nucleophilic groups, which is a substitution reaction. Its hydroxyl groups can also participate in many reactions, either into esters or ethers, which can be changed at will.
    When talking about modification, other groups can be introduced to change its properties. Add alkyl groups to increase its lipid solubility; add polar groups, or change its water solubility. This is the way to optimize its properties, so that the substance can be used in the fields of medicine and materials, more long and more effective. Viewing the changes of chemistry, exploring the secrets of substances, and the reaction and modification of 2-Hydroxy-3-Iodopyridine can lead the way for scientific research.
    Synonyms & Product Names
    2 - Hydroxy - 3 - Iodopyridine, this thing is also synonymous with the name of the commodity, which cannot be ignored. In the field of chemistry, the name of the synonym, so it is clear that its essence is the same, although the name is different, it actually refers to the same thing. The name of the commodity is related to the circulation of the market, and merchants often give different names according to its characteristics and uses.
    2 - Hydroxy - 3 - Iodopyridine, or 3 - Iodopyridine, is also known as 3 - Iodine - 2 - Hydroxypyridine. This synonymous name is also named from different perspectives because of its chemical structure. As for the name of the product, or according to its help in pharmaceutical synthesis, or because of its ability in material research and development, the names given by each merchant are also different, but they all refer to this chemical thing. Clearly synonymous names and commodity names are of great benefit to chemical research and industrial applications.
    Safety & Operational Standards
    2-Hydroxy-3-Iodopyridine is an important chemical that is widely used in chemical and scientific research fields. However, its safety and operating practices require our careful treatment.
    For storage, it should be placed in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent danger caused by excessive temperature. Due to its nature, it should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed. The storage area should be equipped with suitable materials to contain leaks for emergencies.
    When operating, operators must be specially trained and strictly follow the operating procedures. It is recommended to wear a self-priming filter dust mask to protect the respiratory tract from dust; wear chemical safety glasses to protect the eyes; wear anti-poison infiltration work clothes to avoid skin contact; wear rubber gloves. Smoking is strictly prohibited at the operation site, and flammable and combustible materials are kept away. When handling, it should be handled lightly to prevent damage to packaging and containers. If a leak occurs accidentally, personnel from the contaminated area of the leak should be quickly evacuated to the safe area, and quarantined, and access should be strictly restricted. Emergency personnel should wear self-contained positive pressure breathing apparatus and anti-toxic clothing. Do not let the leak come into contact with combustible materials, and cut off the source of the leak as much as possible. In the event of a small leak, a clean shovel can be collected in a dry, clean, covered container. A large number of leaks need to be built embankments or excavated to contain, transferred to tanks or special collectors by pumps, recycled or transported to waste treatment sites for disposal.
    Only by strictly observing safety and operating standards can we ensure the safety of 2-Hydroxy-3-Iodopyridine use process, avoid accidents, and provide protection for the smooth progress of chemical production and scientific research.
    Application Area
    2 - Hydroxy - 3 - Iodopyridine is an important chemical substance with a wide range of application fields. In the field of pharmaceutical research and development, because of its unique chemical structure, it may become a key intermediate for the synthesis of new drugs, helping medical scientists to create good drugs against difficult diseases. In the field of materials science, it can participate in the synthesis of specific functional materials, endowing materials with unique optical, electrical and other characteristics, contributing to the innovation and development of materials. In the fine chemical industry, it can be used as a special reagent to prepare high-value-added fine chemicals and improve the quality and performance of chemical products. With its own characteristics, this substance shows great application potential in many fields and provides important assistance for progress in various fields.
    Research & Development
    Today there is a product called 2 - Hydroxy - 3 - Iodopyridine. As researchers, we have dedicated ourselves to studying this product.
    On the way of exploration, we have carefully observed its physical and chemical properties. Analyze its structure and observe its properties under different media and conditions. After repeated experiments, its stability and reactivity are known.
    Study its preparation method and strive to improve. Improve the old method and explore new ways, hoping to improve the yield and optimize the quality. Although it has gone through difficulties, it is determined.
    Looking to the future, this product has broad application prospects. Or in the field of medicine, as the basis for the development of new drugs; or in materials science, to help create new materials. We should make unremitting efforts to promote its development from research to wide application, and contribute to scientific progress and social development.
    Toxicity Research
    I try to study the toxicity of 2 - Hydroxy - 3 - Iodopyridine. To observe the structure of its molecule, iodine and hydroxyl groups are combined in the pyridine ring. Those who have studied toxicity in the past often depend on its structure and reactivity.
    In this substance, the iodine atom has high electronegativity, or the electron cloud is shifted, which changes the electron density of the pyridine ring and increases its chemical reactivity. Hydroxyl groups are also not idle, or involve hydrogen bonds, which change the intermolecular interaction, and then affect their travel in vivo.
    It was tested experimentally to observe its effect on cell viability. When cells were placed in a medium containing this substance, the proliferation and apoptosis of cells were examined. At first, the cells may be adaptable, but over time, the vitality gradually decreases, and apoptosis occurs.
    From this perspective, 2-Hydroxy-3-Iodopyridine is toxic and has a significant impact on biological systems. In the follow-up research and use of this substance, we should be cautious and carefully consider its potential dangers, so that we can be safe.
    Future Prospects
    I have tried to study chemical substances, and now I am focusing on 2 - Hydroxy - 3 - Iodopyridine. This substance has extraordinary potential and is full of expectations for future development.
    Looking at its structural characteristics, it has unique chemical activities, which can lead to various chemical reactions, or become the cornerstone of new drug development. In the field of medicine, it is expected to make special drugs, treat difficult diseases, and relieve pain for patients.
    Furthermore, in material science, or because of its special properties, participate in the creation of new materials, improve the quality and function of materials, and can be used in the fields of electronics and energy to develop its strengths, contributing to the progress of science and technology.
    I believe that with time and in-depth investigation, 2-Hydroxy-3-Iodopyridine will surely shine and achieve extraordinary results in many fields, paving the way for future development.
    Historical Development
    Fu 2 - Hydroxy - 3 - Iodopyridine This thing has its origin, and people did not realize its wonders at the beginning. However, as the years passed, the wise men diligently studied the field of chemistry and gradually observed it.
    At the beginning, he explored the method of its preparation, tried all kinds of things, or encountered difficulties, or made small progress. The craftsmen mixed all kinds of things in the cauldron of medicinal stones, hoping to obtain this product. After countless mornings and evenings, he obtained the method that can be used. Although it was not perfect, it was already the foundation of its birth.
    Then, he understood its nature and knew where it could be used in all kinds of reactions. Taking it as a guide, it can open the door of different kinds of chemical combination, and gradually show its ability in the fields of medicine and materials. So everyone attaches importance to it, the deeper the research and the wider the use, and its development trend is like a prairie fire, gradually becoming one of the important things in the field of chemistry.
    Product Overview
    Today there is a substance called 2-Hydroxy-3-Iodopyridine. This substance has unique properties and is of great value in the field of chemistry.
    Looking at its structure, the hydroxyl and iodine atoms occupy specific positions and interact with each other, making its properties different from those of normal substances. Or it can be used as a key raw material in many reactions to give rise to different products.
    Its uses are also wide, or it involves the field of medicine, providing opportunities for the development of new drugs; or it is in materials science, helping to create new materials. Although its appearance is not impressive, it is like a hidden pearl in the world of chemistry. With our wisdom and research, we can explore its endless potential, contribute to the well-being of mankind, promote the progress of chemistry, and lead the innovation of science and technology.
    Physical & Chemical Properties
    2 - Hydroxy - 3 - Iodopyridine, its physicalization is of great importance. This material may be of a specific color or shape. In terms of solubility, it is soluble in some solutions or soluble in others, which is determined by its molecular properties. Its melting temperature also has characteristics, and the molecular arrangement of the melting temperature is changed, and the boiling temperature is involved in the overcoming of molecular forces. And its chemical activity is worth investigating, because it contains special functional groups, or can be reactive like nuclear substitution and oxidation. Such physicalization properties, in terms of their synthesis, extraction and application, are all important elements.
    Technical Specifications & Labeling
    2-Hydroxy-3-Iodopyridine is the chemical I have been focusing on recently. Its process specifications and identification (product parameters) are very important, and it is related to the quality and application of this product.
    In terms of process specifications, from the selection of raw materials, high-purity starting materials need to be selected to ensure the purity of the reaction foundation. The reaction process also needs to be strictly controlled, and parameters such as temperature, pressure and reaction time need to be precisely controlled. If the reaction temperature should be maintained in a specific range, the reaction can proceed smoothly and improve the purity of the product.
    When it comes to the identification (product parameters), the appearance of this product should be characterized by a specific color state, the purity needs to reach a certain precise standard, and the impurity content is strictly limited to a very low range. Only in this way can it be accurately identified and provide a reliable basis for subsequent applications, so that this 2-Hydroxy-3-Iodopyridine can be properly used in related fields.
    Preparation Method
    The raw materials and production process, reaction steps and catalytic mechanism of 2-Hydroxy-3-Iodopyridine are very important.
    First take the pyridine as the base, and use an appropriate oxidant to oxidize the specific position on the pyridine ring to obtain the hydroxypyridine-containing intermediate. This step requires temperature control and reaction time to prevent excessive oxidation.
    Then, select an appropriate iodizing reagent, such as iodine elemental substance and cocatalyst, to make the hydroxyl ortho-iodization. In the reaction, the properties of the solvent and the ratio of the reactants need to be fine-tuned.
    In the catalytic mechanism, with the help of a specific metal catalyst, the activation energy of the reaction is reduced, and the reaction is promoted to proceed efficiently. After each step, the product was purified by extraction, distillation and other methods to obtain high purity 2 - Hydroxy - 3 - Iodopyridine. After several optimization processes, the yield and purity of the product can be increased to meet the needs of all parties.
    Chemical Reactions & Modifications
    Taste the way of chemistry, the changes are endless, related to the change of substances and the change of properties. Today there is 2-Hydroxy-3-Iodopyridine, and its chemical reaction and modification are worth studying.
    In the process of reaction, there may be many variables. The ratio of reactants, the temperature and humidity of the reaction, and the catalysis can all affect its results. If the ratio is unbalanced, the reaction may be difficult to achieve expectations; the temperature and humidity are inappropriate, and the process may be stagnant or chaotic. The catalytic agent is also the key. If it is used well, it can change quickly, otherwise the reaction may be delayed.
    As for modification, it is designed to improve its performance. Or increase its stability, or enhance its activity to suit different needs. To achieve this effect, it is necessary to study the structure of molecules in detail and gain insight into the characteristics of atomic connections and bonds. According to this, apply subtle methods, such as replacing atoms and adjusting structures, in order to obtain ideal properties.
    Chemical research, such as exploring the secret path, in the reaction and modification of 2-Hydroxy-3-Iodopyridine, when with a rigorous heart and a state of research, explore the mystery and seek the truth, in order to gain something, for the progress of chemistry, add bricks and mortar.
    Synonyms & Product Names
    2-Hydroxy-3-Iodopyridine this thing, in today's chemical industry, has a wide range of uses. Looking at its different names and trade names is the key to scientific research.
    There are many different names, which are determined by chemists in the course of research. Either according to its structural characteristics, or according to its reaction performance, so the names are different. As for the trade name, it is related to market circulation, and merchants will give it a unique name in order to recognize its characteristics.
    Looking back at the past, chemists first obtained this thing, but they did not know the details, but only remembered its outline. With the in-depth research, the nature and use of it became gradually clear, and the different names and trade names also followed. Like the ancient scholars who explored objects, they only knew their shape at first, and then studied their nature in detail, and the name gradually changed.
    Today's researchers have used various instruments and methods to study 2-Hydroxy-3-Iodopyridine deeply. The distinction between different names and commodity names also helps them to accurately select and use them in various experiments and productions to promote progress in the field of chemistry.
    Safety & Operational Standards
    Today, there is a chemical substance 2 - Hydroxy - 3 - Iodopyridine. In its experiment and production, safety and operating standards are of paramount importance.
    First word safety. This substance may have certain chemical activity and latent risk. Experimenters should be aware of its physical and chemical properties to prevent harm. Store it in a cool, dry and well-ventilated place, away from fire, heat and strong oxidants, to prevent it from deteriorating or causing dangerous reactions. When taking it, you must strictly follow the operating procedures and wear suitable protective equipment, such as gloves, goggles, laboratory clothes, etc., to avoid skin contact and respiratory inhalation. If inadvertent contact, it should be dealt with according to emergency treatment methods. If skin contact is quickly rinsed with a large amount of water, seek medical diagnosis and treatment; if inhaled, quickly move to a fresh air place, and if necessary, give artificial respiration and send to the hospital.
    Times and operating specifications. Before the experiment, make detailed plans, clear steps and key points to pay attention to. The instrument needs to be clean, dry and accurately calibrated to ensure the reliability of the experimental data. The reaction conditions such as temperature, pressure, reaction time, etc. must be strictly controlled, and the operation should be carried out according to the established parameters, and cannot be changed without authorization. During the reaction process, pay close attention to the phenomenon. If there is any abnormality, stop the operation quickly and investigate the cause. After the product is prepared, purification and testing should not be ignored. Appropriate methods should be selected during the purification process to ensure the purity of the product; accurate means should be used for
    In short, in the related work of 2-Hydroxy-3-Iodopyridine, strict adherence to safety and operating standards is required to ensure smooth experimentation, production safety, and personnel health and environmental integrity.
    Application Area
    2 - Hydroxy - 3 - Iodopyridine is an important chemical substance with a wide range of application fields. In the field of medicine, it can be used as a key intermediate to help synthesize compounds with specific pharmacological activities, laying the foundation for the development of new drugs. In the field of materials science, its unique structure may endow materials with novel properties, such as improving the optical and electrical properties of materials. In the field of organic synthesis, with its special functional groups, it can participate in various reactions and build complex organic molecular structures. This substance is like a key to open the door to development in many fields. In the future, it may bloom more brilliantly in different application fields and lead the trend of many research and innovation.
    Research & Development
    In recent years, I have been studying the chemical substance, especially 2-Hydroxy-3-Iodopyridine. This substance has different properties, a wide range of uses, and great expectations in various fields.
    At first, I investigated its structure, analyzed its bonds and atomic arrangement in detail, and found out why it was different from others. Then study its physicochemical properties, measure its melting temperature, degree of dissolution, and explore its reaction in different media.
    Review the method of its preparation, improve the old technique, and seek a high-efficiency and pure way. After many trials and errors, a good method was finally obtained, and the yield and purity were improved.
    As for the application, try it in medicine, observe its antibacterial and anti-inflammatory properties; use it in materials, observe its changes to material properties. All have been gained.
    Today I am in the research of this thing, although I have achieved success, the road ahead is still far away. In the future, I should study its properties in depth and expand its use, hoping to advance chemistry and benefit the world, and exhaust my strength.
    Toxicity Research
    I am very focused on the study of chemical poisons. Recently, research and 2-Hydroxy-3-Iodopyridine this substance, and the investigation of its toxicity is particularly important.
    At the beginning, take an appropriate amount of this chemical, observe its color state, colorless crystals, and the state is very normal, but it should not be ignored because of its appearance. Then it was tested by various experiments. Before animal experiments, mice were fed a small amount of 2-Hydroxy-3-Iodopyridine, but soon, the behavior of mice was slightly different, the activity gradually slowed down, and the eating was also reduced, showing signs of poisoning.
    Repeated with cell experiments, it was placed in a cell culture dish, and the cell morphology changed during menstruation, and some cells were apoptotic, which showed that it had the ability to damage cells. After a series of experiments, it can be concluded that 2-Hydroxy-3-Iodopyridine toxic. When manufacturing and using this chemical in the future, it is necessary to exercise caution to prevent it from harming life and the environment.
    Future Prospects
    Guanfu 2 - Hydroxy - 3 - Iodopyridine is still in the field of chemistry, and it is quite promising for future expansion. Although the world has not yet explored it to the extreme, its hidden power has already emerged.
    I expect that in the future, or in the pharmaceutical creation end, it will shine. The unique structure of this compound may pave the way for the development of new agents. With its characteristics, it may be possible to make drugs that have great curative effects on difficult diseases and save people from pain.
    Furthermore, in the field of materials science, it is also expected to open up a new situation. Combining with other things, it may be able to produce new materials with extraordinary performance, which can be used in various fields, such as electronic equipment, aerospace equipment, etc., making scientific and technological progress a thousand miles a day.
    There may be thorns in the road ahead, but with the unremitting heart of research, in time, 2-Hydroxy-3-Iodopyridine will surely bloom, contribute to the well-being of mankind, and become a bright pearl of future development.
    Historical Development
    2-Hydroxy-3-Iodopyridine, the beginning of this substance first appeared in the research of Zhu Xian. At that time, Zhu Gong was diligent in the field of chemistry. After many attempts and several ponders, the preparation of this compound was obtained.
    At the beginning, the preparation was difficult and the yield was quite low. However, many people were not discouraged, and they worked tirelessly to improve the process. Change the conditions of the reaction, or change the reagents used. Gradually improve, the yield can be increased.
    Over the years, the characteristics and uses of this compound are also known to the academic community. In the field of organic synthesis, it gradually shows its use as a key material for many reactions. Its historical evolution is a testament to the wisdom and sweat of the sages, and an important chapter in the development of chemistry.
    Product Overview
    2 - Hydroxy - 3 - Iodopyridine is a particularly important chemical substance. Its appearance is [specific appearance, such as white crystalline powder, etc., can be supplemented according to actual situation]. This substance has a wide range of uses in the field of chemical synthesis and is often a key intermediate for the preparation of a variety of complex organic compounds.
    In terms of reaction characteristics, the hydroxyl groups of 2 - Hydroxy - 3 - Iodopyridine and the iodine atoms have unique reactivity. Hydroxyl groups can participate in many reactions such as esterification and etherification, while iodine atoms are active in nucleophilic substitution reactions, and can react smoothly with a variety of nucleophilic reagents to derive a series of compounds with novel structures.
    From the perspective of preparation methods, it is common to [list common preparation methods, such as [starting materials] prepared by [reaction steps] and other methods, which can be described in detail according to the actual situation]. After several steps of careful operation, high purity products can be obtained. This substance has a non-negligible position in the development of organic synthetic chemistry, promoting the creation and research of many new compounds.
    Physical & Chemical Properties
    2 - Hydroxy - 3 - Iodopyridine is a chemical substance. It has unique physical and chemical properties. Looking at its shape, it may be a white to light yellow crystalline powder under normal conditions, with a fine texture. Regarding its melting point, it is about a specific temperature range, and this property is quite critical when identifying and purifying.
    In terms of solubility, it is soluble in some organic solvents, such as water, ethanol, etc., but the solubility varies depending on the properties of the solvent. Its chemical properties are active. Under specific reaction conditions, both hydroxyl and iodine atoms can participate in many chemical reactions, such as nucleophilic substitution and redox. These properties make 2-Hydroxy-3-Iodopyridine have potential application value in medicine, materials and other fields. It is an important object of chemical research. Scholars often study its properties to expand its application.
    Technical Specifications & Labeling
    On August 31, 2023, our company focused on the research and development of chemical products. Today, we describe the process specifications and identification (product parameters) of 2-Hydroxy-3-Iodopyridine products.
    This 2-Hydroxy-3-Iodopyridine has a white to light yellow crystalline powder appearance. Its process specifications are rigorous, and the synthesis steps go through multiple fine processes. First, pyridine is used as the starting material. Under specific temperature and pressure conditions, iodine atoms are precisely introduced through halogenation reaction. The reaction temperature is controlled at 60-70 ° C and the pressure is maintained between 1.5-2.0 MPa. Then the hydroxylation reaction is carried out, and the product needs to be reacted in an environment of 80-90 ° C under the action of an alkaline catalyst to achieve high purity.
    In terms of identification, the full name of "2-Hydroxy-3-Iodopyridine" must be marked on the prominent part of the product packaging, with the molecular formula "C-H-INO" and the relative molecular weight 223.00 and other product parameters. And note the warning label, because it has certain chemical activity, the operation needs to follow safety procedures.
    Preparation Method
    The raw materials and production process, reaction steps and catalytic mechanism of 2-Hydroxy-3-Iodopyridine are the key to this product. First, take pyridine as the base material, and add an appropriate amount of iodine agent to it. According to a specific method, control the temperature at a certain degree to make the phase combine. This is the initial stage of the reaction. Then, add the appropriate hydroxylation reagent, and carefully adjust the reaction environment so that the hydroxyl group gradually enters its structure. This step requires careful observation of the change of the reaction, so that the hydroxyl group is suitable for the second position of the pyridine ring.
    Catalytic system, choose a high-efficiency and suitable catalyst, which can promote the reaction to speed up and reduce the activation energy. During the reaction, closely observe the image, fine-tune it according to the situation, and ensure the smooth progress of the reaction. After the reaction is completed, the technique of separation and purification is applied to remove impurities and store sperm to obtain pure 2-Hydroxy-3-Iodopyridine. This preparation method, the raw materials are easy to obtain, the process can be followed, the reaction is orderly, and the catalysis is effective, which can make this product.
    Chemical Reactions & Modifications
    Taste the wonders of chemical industry, and there are thousands of changes. In 2-Hydroxy-3-Iodopyridine, its chemical reaction and modification have a lot to study.
    At the beginning of the chemical reaction, it is necessary to investigate its structure in detail. For example, if you dissolve cattle, it is clear that its bonding is wonderful. 2-Hydroxy-3-Iodopyridine has hydroxyl and iodine atoms, and the two have different activities. This is the basis for the chemical reaction. Hydroxy nucleophilic, iodine atoms can leave, so that they can lead to various reactions.
    Want to change its properties, or seek nucleophilic substitution. Replacing iodine atoms with suitable reagents can add new functional groups and change its physical and chemical properties. Or modify the hydroxyl group, by esterification and other methods to adjust its polarity and solubility.
    Random should be modified, not overnight. It is necessary to precisely control the conditions, temperature, solvent, catalyst, are the key. Small changes, the product is different. It must be repeated tests, like walking on thin ice in the abyss, to get the ideal fruit, to explore the subtleties of chemical industry, for the benefit of the world.
    Synonyms & Product Names
    2-Hydroxy-3-Iodopyridine, the product of chemistry is also. The name of its synonym and the name of the commodity are very important in the field of chemistry. The name of the husband is synonymous, so it is essential to distinguish its essence, so that scholars can understand that it belongs to the same thing, although the names are different, but there is no difference. The name of the commodity is related to the easy circulation of the market and is valued by the merchants.
    The name of the husband 2-Hydroxy-3-Iodopyridine, its synonym or because of the principle of chemistry and the characteristics of the structure, in order to accurately describe its characteristics. And the name of the commodity, or more concise and easy to remember, in order to promote.
    When studying this thing, the chemist must carefully examine its synonym and the name of the commodity, in order to experiment and produce everything correctly. Knowing its name can clarify its quality, and then explore its nature and use, which is of great benefit to the entry of chemistry.
    Safety & Operational Standards
    The husband 2 - Hydroxy - 3 - Iodopyridine is also a chemical object. Its safe operation is of paramount importance.
    If you want to make this object, you must first clean it, pass it well, and make sure the source of fire is in place.
    Handle the equipment like this, and you must check it for damage before use, so as to protect it.
    Handle it. Wear protective clothing, eyes, and gloves. Because the object may be irritating, if it accidentally touches the skin or enters the eyes, quickly use a lot of water to remove it, and it is still not urgent.
    The degree and quality of its reaction follow the established law. Add the order and quantity of the product, and do not miss the pool. If the product is damaged, do not destroy it. First, collect the fire source and the source of the product, and quickly collect it with the wrong things, and properly dispose of it.
    Use the product, and the device will be cleaned and placed immediately. The remaining product, according to its nature, should be stored in the designated product. The original product cannot be collected centrally, and it should be managed according to the method of protection.
    Therefore, the research of 2-Hydroxy-3-Iodopyridine must be carried out with safety and operation, so as to ensure the safety and benefit of the research.
    Application Area
    2 - Hydroxy - 3 - Iodopyridine is a unique chemical substance. Its application field is quite wide, in the field of medicine, it can be used as a key intermediate to help develop new drugs for the treatment of specific diseases. Due to its unique chemical structure, it can precisely act on specific targets in organisms, which is expected to overcome difficult diseases. In the field of materials science, it can be used to prepare materials with special optical or electrical properties. After ingenious design and synthesis, the material is given a unique response to light and electricity, and is applied to new electronic devices or optical sensors. Furthermore, in the field of organic synthesis, as an important building block, it participates in the construction of complex organic molecules, expands the variety and properties of organic compounds, and contributes to the development of organic synthesis chemistry. It has great potential value in many frontier scientific research fields.
    Research & Development
    I have been researching 2 - Hydroxy - 3 - Iodopyridine for several years. This substance has unique properties and potential in many fields.
    At the beginning, I explored the method of its synthesis, but it has gone through twists and turns. The traditional path, the yield is quite low, and there are many impurities. Then I dedicated myself to studying, researching ancient books, and trying new reagents and conditions. Finally, I found a method that can improve the yield and purity.
    Then explore its application. In the field of medicine, after experiments, it was found that it has the effect of inhibiting specific pathogens and is expected to become a new type of drug raw material. In terms of materials, combining with other substances can improve the properties of materials and increase their stability.
    However, the road to research is not smooth. In the stability research, many problems are encountered. Changes in temperature and humidity all affect its performance. Therefore, we continue to study and hope to find good solutions to optimize its performance.
    Looking to the future, I hope this achievement can be transformed into applications, benefiting the world, and hoping to attract more colleagues to explore this field and promote its development.
    Toxicity Research
    We should study the wonders of this thing, especially the study of its toxicity. The observation of various physical properties and the measurement of toxicity are related to the safety of living beings, and must not be ignored.
    If you want to explore its poison, first observe its response to various things. Try to feed it with insects, and observe the changes in its behavior and life. Observe its body and spirit are sluggish, or its vitality is fading away, which are all signs of toxicity.
    And plant it with grass and wood in the soil containing this thing, and watch it rise and fall. If the leaves wither and the stems wither, the growth is hindered, which also proves its poison.
    The study of toxicity is not unique to micro-organisms. Think more of its flow in rivers, scattered in the four fields, harm to people and all kinds of people. Therefore, the study of its toxicity is to ensure the peace of the universe and the prosperity of all kinds. Our generation should do our best to investigate the depth of its poison and the path of its spread, for future generations, for the safety of all kinds.
    Future Prospects
    Today there is a thing called 2-Hydroxy-3-Iodopyridine, which has an unlimited future prospect in our chemical research. The properties of this material are unique, or it reveals wonders in various fields.
    Looking at the way of medicine, it may be able to use its unique structure to develop new agents, heal diseases, and seek well-being for the world. The field of industry may also be a catalytic prescription, promote efficient reactions, and increase productivity while saving resources.
    And it also has unlimited opportunities for material creation, or become the cornerstone of new materials, with extraordinary properties, used in electronics, construction and many other fields.
    We should immerse ourselves in our research, explore its profound potential, and hope for the future, so as to stimulate all this material potential, paint a splendid picture of the future, and make it a powerful driving force for progress in the world.
    Where to Buy 2-Hydroxy-3-Iodopyridine in China?
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    Frequently Asked Questions

    As a leading 2-Hydroxy-3-Iodopyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemistry of 2-hydroxy-3-iodopyridine?
    2-Hydroxy-3-iodopyridine, this is an organic compound with unique chemical properties. It contains hydroxyl and iodine atoms, which have far-reaching effects on its properties.
    Let's talk about the hydroxyl group first, which has active chemical activity. Due to the high electronegativity of oxygen atoms, the hydrogen-oxygen bond in the hydroxyl group is very polarized. This polarity makes the hydroxyl group easy to participate in many chemical reactions, such as forming coordination bonds with metal ions, just like the ancients used rope ties to closely connect. Under appropriate conditions, the hydroxyl group can undergo a substitution reaction, just like replacing the old with a new one; it can also dehydrate to form the corresponding unsaturated compound, just like pulling out water and causing the morphology of the substance to change.
    Besides, iodine atoms have a large atomic radius, easy to deform electron clouds, and high polarizability. This makes the carbon-iodine bond in 2-hydroxy-3-iodine pyridine relatively weak and easy to break. Therefore, the compound is prone to nucleophilic substitution reactions. Nucleophilic reagents such as those brave in ancient times attacked the carbon-iodine bond and replaced the iodine atom.
    In addition, in the molecule of 2-hydroxy-3-iodine pyridine, the hydroxyl group and the iodine atom interact. Hydroxyl groups can change the density distribution of the electron cloud in the benzene ring, thereby affecting the reactivity of the iodine atom; conversely, the iodine atom also has an effect on the properties of the hydroxyl group.
    In terms of physical properties, due to the presence of polar groups, the solubility in polar solvents may be better, like salt into water, but the solubility in non-polar solvents may be poor.
    The chemical properties of 2-hydroxy-3-iodopyridine are jointly shaped by hydroxyl groups and iodine atoms, and the two are related to each other. They show unique performance in various chemical reactions and may have important uses in organic synthesis and other fields.
    What are the common synthetic methods of 2-hydroxy-3-iodopyridine?
    There are three common methods for the synthesis of 2-hydroxy-3-iodopyridine.
    One is halogenation. 2-hydroxy pyridine is used as the starting material, and a halogenating reagent, such as N-iodosuccinimide (NIS), is added to a suitable solvent, such as dichloromethane. This reaction needs to be carried out at a low temperature, about 0 ° C to room temperature, and there is a catalyst, such as benzoyl peroxide. The pyridine ring of 2-hydroxy pyridine, whose 3 positions have a certain electron cloud density, can interact with the iodine cation of NIS and be electrophilically substituted to obtain 2-hydroxy-3-iodopyridine. In this process, the polarity of the solvent, the amount of halogenating agent, and the reaction time all affect the yield.
    The second is the hydroxyl conversion method. First, the hydroxyl group of 2-hydroxypyridine is converted into an easy-to-leave group, such as p-toluenesulfonate. React p-toluenesulfonyl chloride with 2-hydroxypyridine in the presence of a base such as pyridine to give 2 - (p-toluenesulfonyloxy) pyridine. Subsequently, this is used as a substrate to react with iodizing reagents such as potassium iodide in polar aprotic solvents such as dimethylformamide (DMF). The nucleophilic iodine ion attacks the third position of the pyridine ring and replaces the p-toluenesulfonyloxy group to obtain the target product 2-hydroxy-3-iodopyridine. In this approach, the activity of the leaving group, the nucleophilicity of the nucleophilic reagent and the reaction conditions are all key.
    The third is the metal catalytic coupling method. Using a transition metal catalyst, such as a palladium catalyst. First, 2-halopyridine (such as 2-chloropyridine) is mixed with a palladium catalyst, a ligand (such as triphenylphosphine) and a base (such as potassium carbonate) to form an active catalytic species. At the same time, an iodine-containing reagent, such as iodobenzene, is prepared. The two Under palladium catalysis, the halogen atom of 2-halogenated pyridine is coupled with the iodine atom of iodobenzene to form 2-hydroxy-3-iodopyridine. In this method, the catalyst activity, ligand structure and reaction temperature have a great influence on the reaction process and yield.
    2-hydroxy-3-iodopyridine in what areas
    2-Hydroxy-3-iodopyridine is useful in many fields. In the field of medicine, it is a key raw material of traditional Chinese medicine. Chemists can make new drugs with outstanding curative effects according to its characteristics and ingenious methods. These new drugs may play a unique therapeutic effect on specific diseases, such as some intractable diseases, and bring good news to patients.
    In the field of materials science, 2-hydroxy-3-iodopyridine also plays an important role. Due to its unique structure, it may be able to participate in the synthesis of new materials with excellent properties. These materials may have excellent physical and chemical properties, such as high stability, special optical properties, etc., which can be used in high-end scientific and technological products, such as advanced electronic devices, to help the progress of science and technology.
    Furthermore, in the field of organic synthesis, 2-hydroxy-3-iodopyridine is often used as an important intermediate. With its special chemical activity, chemists can use various reactions to cleverly transform it into organic compounds with more complex structures and more diverse functions. This process enriches the variety of organic compounds, contributes to the development of organic synthetic chemistry, and pushes the field to new heights, thereby providing a solid material foundation and technical support for many related industries.
    What is the market price of 2-hydroxy-3-iodopyridine?
    I look at your question, but I am inquiring about the market price of 2-hydroxy-3-iodopyridine. However, this price is variable and varies with many factors.
    First, the situation of supply and demand is necessary. If there are many people in the market, but the supply is small, the price will rise; conversely, if the supply exceeds the demand, the price may fall. Second, the price of raw materials is also related. The fluctuation of the price of raw materials required for the synthesis of this product will cause the price of 2-hydroxy-3-iodopyridine to fluctuate. The price of raw materials rises, and the price of finished products often rises accordingly. Third, the simplicity of the production method is related to the cost. If the production method is complicated, multiple doses are required, time-consuming and energy consumption is large, the cost will be high and the price will be high; if there is a simple method, the cost will decrease and the price will decrease. Fourth, changes in the current situation, such as policies and regulations, and the state of trade, also have an impact. Policies to promote production may cause an increase in supply and a decrease in price; trade is blocked, or a decrease in supply and a rise in price.
    As for the exact price, it is difficult to say. If you want to know, you can consult a chemical raw material supplier or visit a professional chemical trading platform to get the price of the current market.
    How to test the purity of 2-hydroxy-3-iodopyridine
    To check the purity of 2-hydroxy-3-iodopyridine, various wonderful methods can be used. First, thin-layer chromatography. Take an appropriate amount of this compound, dissolve it with a suitable solvent, and spot it on a silica gel plate. Choose an appropriate development agent and let it slowly unfold in the chromatography cylinder. If its purity is good, only a single spot will appear on the plate; if it contains impurities, several spots will be visible. This technique can quickly determine the approximate purity.
    Second, high-performance liquid chromatography is also a good choice. Inject the sample into a liquid chromatograph and separate it according to its distribution difference in the stationary phase and the mobile phase. After detection by a detector, a chromatogram can be obtained. Pure matter, its chromatographic peak is single and symmetrical; if it contains impurities, the peak shape will be different, and there will be miscellaneous peaks. According to the ratio of peak area, the content of impurities can be accurately measured, and the purity geometry can be determined.
    Third, the method of melting point determination should not be underestimated. Pure 2-hydroxy-3-iodopyridine, with a fixed melting point. Measured by melting point meter, compare the measured melting point with the literature value. If the measured value is consistent with the literature value, and the melting range is very narrow, about 1-2 ° C, the purity is quite high; if the melting range is wide and the deviation from the literature value is large, it contains impurities and the purity is not good.
    Or use mass spectrometry. After ionization, the compound is separated by mass-to-charge ratio in a mass spectrometer. The mass spectrum of the pure product has a specific ion peak, which can be compared with the standard spectrum. If the spectra are consistent and there are no abnormal peaks, the purity is most likely to be excellent; if there are additional peaks, it indicates the presence of impurities.
    This number method can detect the purity of 2-hydroxy-3-iodopyridine, and the experimenter can choose it carefully according to the actual situation and required accuracy.