2 Hydroxy 5 Iodobenzoic Acid
Iodobenzene

2 Hydroxy 5 Iodobenzoic Acid

Fengxi Chemical

Specifications

HS Code

933915

Chemical Formula C7H5IO3
Molar Mass 266.02 g/mol
Appearance Solid (usually white or off - white)
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in some polar organic solvents like ethanol
Melting Point Around 169 - 172 °C
Boiling Point Decomposes before boiling
Acidity Pka Around 2.8 - 3.2
Iodine Content Contains iodine atom in the molecule
Functional Groups Carboxyl group (-COOH) and hydroxyl group (-OH)
Chemical Formula C7H5IO3
Molecular Weight 266.02
Appearance Solid
Melting Point 195 - 200 °C
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in some organic solvents like ethanol
Pka Value Around 3 - 4
Odor Odorless
Name 2-hydroxy-5-iodobenzoic acid
Chemical Formula C7H5IO3
Molar Mass 266.017 g/mol
Appearance Solid (presumably white or off - white, typical for many organic acids)
Solubility In Water Slightly soluble (due to the polar carboxyl and hydroxyl groups but limited by the non - polar benzene ring)
Pka Around 3 - 4 (carboxylic acid group is acidic)
Melting Point Typically in the range of 150 - 180 °C (approximate value for many aromatic carboxylic acids with substituents)
Boiling Point Decomposes before boiling (common for many organic acids with heat - sensitive functional groups)
Density Estimated to be around 2 g/cm³ (based on related aromatic carboxylic acid derivatives)
Odor Odorless or faint odor (common for many solid aromatic organic acids)
Chemical Formula C7H5IO3
Molar Mass 266.017 g/mol
Appearance Solid
Solubility In Water Slightly soluble
Melting Point 169 - 173 °C
Boiling Point Decomposes
Pka Approx. 2.9 (estimated for carboxyl group)
Odor Odorless (usually)
Packing & Storage
Packing 250g of 2 - hydroxy - 5 - iodobenzoic acid packaged in a sealed plastic bottle.
Storage 2 - Hydroxy - 5 - iodobenzoic acid should be stored in a cool, dry place away from direct sunlight. Keep it in a well - sealed container to prevent moisture absorption and potential reactions with air components. Avoid storing near heat sources or flammable materials. Due to its chemical nature, it should be stored separately from incompatible substances to ensure safety and maintain its integrity over time.
Shipping 2 - Hydroxy - 5 - iodobenzoic acid is shipped in well - sealed containers, safeguarded from moisture and heat. Compliance with chemical shipping regulations ensures safe transportation, often via specialized carriers handling hazardous chemicals.
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2-hydroxy-5-iodobenzoic Acid 2-hydroxy-5-iodobenzoic Acid 2-hydroxy-5-iodobenzoic Acid
General Information
Frequently Asked Questions
What are the main uses of 2-hydroxy-5-iodobenzoic Acid?
2-Hydroxy-5-iodobenzoic acid, this is an organic compound. It has a wide range of uses and can be used as a key pharmaceutical intermediate in the field of medicine. Due to its specific chemical structure and activity, the compound can be converted into many biologically active substances through chemical reactions, which can be used to synthesize drugs for the treatment of specific diseases. For example, in the preparation of some antibacterial and anti-inflammatory drugs, it may play an indispensable precursor role.
In the field of materials science, it also has its uses. With its own characteristics, it can participate in the synthesis of polymers, coatings and other materials. When introduced into a specific material system, it may improve the properties of materials such as optics, electricity, and heat. For example, when preparing polymeric materials with special optical properties, 2-hydroxy-5-iodobenzoic acid may participate in the polymerization reaction as a functional monomer, giving the material unique optical properties.
In the field of organic synthesis, it is often an important starting material or intermediate. Organic chemists can use various functional group conversion reactions to construct more complex organic molecular structures. For example, through esterification, halogenation, coupling and other reactions, the molecular framework can be expanded to synthesize a series of organic compounds with different functions and uses. Due to the existence of hydroxyl and carboxyl groups in its structure, it provides many possible paths for various reactions, assisting in the synthesis of various target products, and meeting the needs of specific organic compounds in different fields.
What are the physical properties of 2-hydroxy-5-iodobenzoic Acid?
2-Hydroxy-5-iodobenzoic acid, this is an organic compound. Its physical properties are quite important and are related to many chemical applications.
Looking at its properties, at room temperature, 2-hydroxy-5-iodobenzoic acid is often in the state of white to light yellow crystalline powder. This form is easy to store and use, and due to the characteristics of the powder, when participating in chemical reactions, it can have a large contact area with other substances, which is conducive to the progress of the reaction.
When it comes to the melting point, the melting point of this compound is within a specific range. The exact melting point value is of great significance for the identification and purification of this substance. By measuring the melting point, the purity of the substance can be judged. If the melting point is consistent with the standard value, the purity is high; if there is a deviation, it may contain impurities.
Solubility is also a key physical property. 2-Hydroxy-5-iodobenzoic acid has different solubility in different solvents. In some organic solvents, such as ethanol and acetone, it has a certain solubility. This property makes it possible to dissolve it in organic synthesis with the help of these solvents to participate in various reactions. In water, its solubility is relatively small, and this difference helps to separate and purify it by solvent extraction and other methods.
In addition, the density of 2-hydroxy-5-iodobenzoic acid is also a specific value. The physical property of density has practical value in the conversion of quantity and volume of substances, and is indispensable for accurate measurement and reaction ratio in practical application scenarios such as chemical production.
The physical properties of 2-hydroxy-5-iodobenzoic acid, from its properties, melting point, solubility to density, play a key role in its research, synthesis, separation and application in the field of chemistry. Only by deeply understanding these properties can we better use this compound in various chemical processes.
What is the chemical synthesis method of 2-hydroxy-5-iodobenzoic Acid?
The method of preparing 2-hydroxy-5-iodobenzoic acid has been known for a long time. To obtain this compound, the following steps are often followed.
Starting material, usually 2-hydroxy benzoic acid is taken as the base. This substance is a common raw material for organic synthesis, which is easy to obtain and inexpensive. Starting with it, iodine atoms can be introduced.
The method of iodine substitution often uses iodine and an appropriate oxidizing agent to cooperate. Common oxidizing agents, such as hydrogen peroxide, the combination of concentrated sulfuric acid and potassium iodate, etc. Take hydrogen peroxide as an example, add 2-hydroxy benzoic acid to an appropriate solvent, such as glacial acetic acid, and then slowly add the mixture of iodine and hydrogen peroxide. Glacial acetic acid can fully disperse the reactants, which is conducive to the reaction. During the reaction, temperature control is very critical, usually at a moderate temperature, such as 40-60 degrees Celsius, continuous stirring. Hydrogen peroxide slowly releases oxygen atoms, which promotes the electrophilic substitution of iodine with the benzene ring of 2-hydroxybenzoic acid, and the iodine atom is then connected to the 5 position of the benzene ring to obtain the precursor of 2-hydroxy-5-iodobenzoic acid.
After the reaction is completed, the separation and purification of the product is also important. The organic product can be separated from the aqueous phase by extraction with a suitable solvent, such as dichloromethane. Then, the dichloromethane is removed by distillation, and the crude product can be obtained. In order to obtain high-purity 2-hydroxy-5-iodobenzoic acid, recrystallization is still required. A mixed solvent of ethanol and water is appropriate, the crude product is dissolved by heating, and then slowly cooled. The high-purity crystals then precipitate, and after filtration and drying, it is the target product 2-hydroxy-5-iodobenzoic acid. This is the approximate ancient method for preparing 2-hydroxy-5-iodobenzoic acid. In practice, it is necessary to fine-tune various conditions according to specific circumstances to obtain satisfactory results.
2-hydroxy-5-iodobenzoic Acid in storage and transportation
2-Hydroxy-5-iodobenzoic acid is an organic compound. When storing and transporting, more attention should be paid.
First words storage. This substance should be placed in a cool, dry and well-ventilated place. If it is placed in a high temperature and humid place, it may cause its properties to change. Because of its certain chemical activity, high temperature is prone to chemical reactions, moisture or hydrolysis and other changes, which will damage its quality. It should be kept away from fires and heat sources to prevent accidents due to heat. And it should be stored separately from oxidizing agents, reducing agents, alkalis, etc. Because the compound may be incompatible with other such substances, co-storage may cause violent reactions and endanger safety.
Second talk about transportation. When transporting, be sure to ensure that the packaging is complete and sealed. If the packaging is damaged, the substance or leakage will not only cause material loss, but also pollute the environment, and even pose a hazard to transporters. Transportation vehicles should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. During driving, it is necessary to prevent exposure to the sun, rain, and high temperature. Summer transportation should be selected in the morning and evening to avoid the extreme heat during the day. When transporting, it should also follow the specified route, and do not stay in densely populated areas and busy cities for a long time.
In short, in the storage and transportation of 2-hydroxy-5-iodobenzoic acid, it is necessary to strictly follow relevant norms and requirements, and operate with caution to ensure safety.
What is the market price of 2-hydroxy-5-iodobenzoic Acid?
2-Hydroxy-5-iodobenzoic acid, an important organic compound in the field of fine chemicals, is widely used in many industries such as medicine, pesticides and materials. As for its market price, it is difficult to determine accurately, because it is affected by many factors.
The first to bear the brunt is the cost of raw materials. The price fluctuations of raw materials required for the synthesis of 2-hydroxy-5-iodobenzoic acid, such as specific phenols and iodides, are directly related to the cost of the final product. If the supply of raw materials is tight or the market price rises, the price of 2-hydroxy-5-iodobenzoic acid will also rise.
Furthermore, the complexity of the production process is closely related to the cost. If the preparation process requires a multi-step reaction and the reaction conditions are strictly controlled, such as precise temperature and pressure control, or the use of special catalysts, this will lead to a significant increase in production costs, which will push up the market price.
The market supply and demand relationship is also a key factor. If downstream industries such as pharmaceuticals have strong demand for 2-hydroxy-5-iodobenzoic acid and relatively insufficient production supply, the price will rise; conversely, if the market demand is weak and the supply is excessive, the price will tend to fall.
In addition, different manufacturers have different product prices due to differences in production scale, technical level and management efficiency. Large-scale manufacturers may reduce unit costs due to scale effects, and prices may be competitive; those with advanced technology and efficient management can also have an advantage in cost control.
According to past market conditions and comprehensive consideration of various factors, the price of 2-hydroxy-5-iodobenzoic acid fluctuates roughly between hundreds and thousands of yuan per kilogram. However, this is only a rough estimate, and the actual market price will change in real time with the dynamic changes of the above factors. To know the exact price, practitioners need to pay close attention to market dynamics and communicate in depth with relevant suppliers in order to obtain accurate quotations.