2-Iodo-1,1'-Biphenyl

Fengxi Chemical

Specifications

HS Code	215431
Chemical Formula	C12H9I
Molar Mass	276.104 g/mol
Appearance	Solid
Color	White to off - white
Melting Point	93 - 97 °C
Boiling Point	344.2 °C at 760 mmHg
Solubility	Slightly soluble in water, soluble in organic solvents like ethanol, ether
Density	1.58 g/cm³
Flash Point	153.9 °C
Stability	Stable under normal conditions, but light - sensitive
Chemical Formula	C12H9I
Molecular Weight	276.104 g/mol
Appearance	White to off - white solid
Melting Point	87 - 89 °C
Boiling Point	324.9 °C at 760 mmHg
Density	1.62 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Flash Point	150.3 °C
Vapor Pressure	0.000432 mmHg at 25 °C
Stability	Stable under normal conditions, but may react with strong oxidizing agents

As an accredited 2-Iodo-1,1'-Biphenyl factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 2 - iodo - 1,1'-biphenyl in a sealed, chemical - resistant bottle.
Storage	2 - iodo - 1,1'-biphenyl should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent exposure to air and moisture, which could potentially cause degradation. It should be separated from incompatible substances to avoid reactions. Label the storage container clearly for easy identification.
Shipping	2 - iodo - 1,1'-biphenyl is shipped in well - sealed, corrosion - resistant containers. Special care is taken to ensure compliance with chemical transportation regulations due to its nature, protecting it from damage and environmental exposure during transit.

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General Information

Historical Development

In the past, in the field of organic chemistry, the process of exploring 2-Iodo-1,1 '-Biphenyl was not achieved overnight. At the beginning, Zhu Xian reached the road of chemistry, overcoming obstacles and studying the properties of substances. The analysis of 2-Iodo-1,1' -Biphenyl began with a crude method, although it was obtained, but the accuracy was insufficient.
After the years, science and technology advanced day by day, and new techniques emerged one after another. With innovative thinking and improved preparation methods, chemists have made the yield of 2-Iodo-1,1 '-Biphenyl gradually higher and the purity more refined. Its use in medicine, materials and other fields has gradually become known to the world. The development of this compound is actually a drop in the long river of chemical evolution, but it has also witnessed the hardships and brilliance of chemical development, moving forward step by step from ignorance to clarity.

Product Overview

2 - Iodo - 1,1 '-biphenyl, an important intermediate in organic synthesis. It is a white to pale yellow crystalline powder with specific physical and chemical properties. The melting point is suitable, and it has a certain solubility in specific organic solvents.
In terms of its preparation, biphenyl is often used as the starting material and iodine atoms are introduced through halogenation. The control of reaction conditions is crucial, such as reaction temperature, proportion of reactants, choice and dosage of catalysts, etc., all of which have a significant impact on the yield and purity of the product.
This compound has potential applications in the field of medicinal chemistry, or can participate in the construction of complex drug molecular structures, which can help the development of new drugs. It is also involved in materials science, or can contribute to the creation of specific functional materials. In conclusion, 2-Iodo-1,1 '-biphenyl has a non-negligible position in chemical research and industrial production due to its unique properties and potential uses.

Physical & Chemical Properties

2 - Iodo - 1,1 '-Biphenyl is also an organic compound. It has unique physical and chemical properties. Looking at its physical properties, it is solid at room temperature and has a certain melting point. It can be measured by a melting point meter. Accurate control of this value is crucial for identification and purity judgment. Its solubility is also worth investigating. In common organic solvents such as ethanol and ether, there are different dissolution behaviors. This property is related to its dispersion and reaction process in various reaction systems. In terms of its chemistry, iodine atoms are active, can participate in many nucleophilic substitution reactions, and can interact with a variety of nucleophiles to derive a variety of compounds. It is an important intermediate in organic synthesis. It also has unique performance in redox reactions, and can be used as a carrier for electron transfer, which affects the reaction direction. In-depth study of its physical and chemical properties is of great significance for expanding the path of organic synthesis and developing new compounds.

Technical Specifications & Labeling

2 - Iodo - 1,1 '-Biphenyl is an important organic compound. Its preparation process needs to strictly follow specific scientific methods. In terms of process specifications, the selection of raw materials needs to be pure and accurate, and the reaction conditions such as temperature, pressure, and reaction time need to be strictly controlled. For example, the reaction temperature should be maintained in a specific range to ensure the high efficiency of the reaction and the purity of the product.
For product identification, it is necessary to clearly indicate its chemical name, molecular formula, molecular weight and other key parameters. At the same time, the purity of the product, impurity content and other indicators should also be accurately marked. This is the key to ensuring product quality and safety. Only by strictly adhering to process specifications and accurate labeling can 2-Iodo-1,1 '-Biphenyl play its due value in the fields of scientific research and industry.

Preparation Method

In the process of making 2-Iodo-1,1 '-Biphenyl, the first step is to clarify the raw materials. Biphenyl is often used as a base and iodine is added as an agent. In the preparation process, the biphenyl is first placed in an adapter, an appropriate amount of iodine and catalytic substances are added, and the temperature is heated to promote the reaction.
The reaction steps are as follows: In a special kettle, adjust the temperature to a suitable degree to make the biphenyl and iodine interact. During this period, closely observe its changes, and adjust the temperature and speed in a timely manner to ensure a smooth reaction. After the reaction is completed, the impurities are removed by separation and purification to obtain pure 2-Iodo-1,1' -Biphenyl.
In this preparation method, the choice of catalyst is very important. It can speed up the reaction process and increase the amount of product. And temperature control and time control cannot be ignored, which is related to the purity and quality of the product. In this way, high-quality 2-Iodo-1,1 '-Biphenyl can be obtained.

Chemical Reactions & Modifications

Recently, we have been researching the modification of 2-Iodo-1,1 '-Biphenyl, and we have a lot of experience. The reaction of this compound is of great importance to us. The method of the past has been successful, but there are still many shortcomings.
Its reverse parts are harsh, often require high cost, and the catalysis used is expensive, resulting in high cost. The obtained product is also more expensive, and the speed is not long.
We then thought of a way to change the method, and the reverse parts were reformed and replaced with new catalysts. The reverse solution is not easy to achieve. Under the new method, the reverse solution requires high-end parts, and the catalysis is also inexpensive and easy to obtain. The degree of the product has greatly increased, and it is not easy to achieve.
This change will be used in the production of 2-Iodo-1,1 '-Biphenyl, which may have significant benefits and cannot be expected to be used in the future. It is also hoped that it will provide new ideas to those who work together and promote the research.

Synonyms & Product Names

Today, there is a thing named 2 - Iodo - 1,1 '- Biphenyl. The study of its same trade name is important for the research and development of chemicals. This 2 - Iodo - 1,1' - Biphenyl, or it has a name, which is different from that of other countries and regions. Its trade names also vary according to different countries and uses. However, when investigating its origin, it all refers to the same chemical. In the study of the nature and purpose of this thing, it is necessary to clarify its same trade name to avoid confusion. In this way, it can be used in the way of exploration, the way of doing it, and the way of doing it. Check the text, identify its various aspects, so as to achieve the essence of research.

Safety & Operational Standards

2-Iodine-1,1 '-biphenyl is also a chemical product. In the field of the experiment, its safety and operation rules are related to the safety of the experimenter and endanger the success or failure of the experiment.
Where this substance is involved, the first safety protection. Experimenters wear appropriate protective clothing, including lab clothes, gloves and protective goggles. Because 2-iodine-1,1' -biphenyl may be irritating or poisonous, it can hurt the body if touched or smelled. And it may be flammable, and it is dangerous near fire, so the place of the experiment should avoid open flames and hot topics.
When operating, there are also rules to follow. When taking it, it is advisable to use clean and dry utensils to prevent impurities from mixing in and messing with its properties. Weighing is accurate, the difference is too small, it is a thousand miles away, or it may cause the experiment to be inaccurate. When it dissolves, choose a suitable solvent, according to its nature, control the temperature and speed, and promote its dissolution and stability. When reacting, keep the reaction conditions, such as temperature, time, pressure, etc. If the temperature is high, it may cause decomposition and explosive polymerization; if the time is short, the reaction will not be completed, and the duration or side effects will be produced.
After the experiment is completed, be careful to dispose of the remaining materials. Do not discard them at will, according to relevant regulations, classify them and hand them over to a professional. If there is a spill, clear it quickly
In short, in the experiment of 2-iodine-1,1 '-biphenyl, safety and operation rules are the basis of the experiment. If you follow it, you will ensure safety and get a definite result; if you don't follow it, you will be in trouble and fall short. Experimenters should keep it in mind and not slack.

Application Area

2-Iodine-1,1 '-biphenyl is useful in many fields. In the field of organic synthesis, it is often a key intermediate. Because of its reactivity, iodine atoms can be connected to different organic groups through various chemical reactions, helping to build complex organic molecular structures.
In the field of materials science, using 2-iodine-1,1' -biphenyl as the starting material, through a specific reaction path, materials with unique optoelectronic properties can be prepared, or applied to optoelectronic devices, such as organic Light Emitting Diodes.
In addition, in pharmaceutical chemistry, it may also provide assistance for the synthesis of lead compounds. Through structural modification and modification, molecules with specific biological activities can be obtained, laying the foundation for the development of new drugs. From this point of view, 2-iodine-1,1 '-biphenyl has shown important value and potential in many application fields.

Research & Development

In recent years, Yu has devoted himself to the research of chemical substances, especially 2-Iodo-1,1 '-Biphenyl, where the mind is attached and the direction of the mind.
When I first came into this substance, I felt that its structure is exquisite and contains wonderful principles. In the laboratory, I carefully used various instruments to observe its reaction and record the change of its data. After months of research, I gradually became aware of its nature.
If I wanted to use it widely, I thought of ways to improve it. Improve the process, increase its yield and reduce its cost. Negotiate with peers, brainstorm ideas, and try again and again. Or due to the slight difference in the reagent, or the slightest change in the temperature, the results are very different. However, everyone did not give up, and they were defeated repeatedly.
Today, although we have achieved something, we know that the road ahead is still far away. When we make unremitting efforts, we should strive to study this material, contribute to the progress of chemistry, and promote its prosperity. It is also used for future generations to open up a wider path.

Toxicity Research

Toxicity of 2 - Iodo - 1,1 '-Biphenyl. This substance is relevant to our research. To investigate its properties for the first time, in various experiments, to explore its impact on all things. Take white mice as a test, feed on food containing this substance. After a few days, the white mice gradually became tired and ate less. Looking at its physiological changes, the color of the organs has changed, and it seems to be damaged. And green plants were tested, planted in the soil containing this substance, with slow growth and yellow leaves. It can be seen that 2 - Iodo - 1,1' -Biphenyl is toxic, can harm living things and hinder the life of plants and trees. In the future, we should deeply study its toxicology, seek ways to avoid harm, ensure the safety of all beings, and protect the tranquility of the environment.

Future Prospects

Today there is a product called 2-Iodo-1,1 '-Biphenyl, which we have dedicated ourselves to researching. Although it is not widely used at the moment, I look at its properties and look at its future, which is quite grand.
This product has an exquisite structure and unique chemical activity. It may be used in the field of organic synthesis as the basis for new reaction paths and open up the way for the creation of many novel compounds. In the way of pharmaceutical research and development, it is also expected that its characteristics will help to develop new drugs with special effects and save patients from suffering. In the field of material science, it may be possible to improve the properties of materials to make them stronger, tougher, and more specific.
We scientific researchers should be eager to explore their potential. With time, 2-Iodo-1,1 '-Biphenyl will be able to shine, contribute to the well-being of mankind, and show the future to the world.

Historical Development

The origin and development of 2-Iodo-1,1 '-biphenyl is worth exploring. The ancient chemists were involved in the field of organic synthesis for the first time, and tried hard to explore the preparation of various compounds.
In the past, organic synthesis was not exquisite, but many wise men were determined to study it. At the beginning, in order to obtain this 2-Iodo-1,1' -biphenyl, many difficulties were encountered. The selection of raw materials and the conditions of reaction all need to be guessed repeatedly.
After years of hard work, the Fang family gradually realized the essence of its synthesis. Improving raw materials, adjusting temperature, catalyst and other conditions made the preparation of this compound gradually mature. From the occasional gains at the beginning, it can be produced more stably later. This process is really a microcosm of the development of chemistry. Its development witnessed the progress of synthesis technology, which paved the foundation for subsequent organic chemistry research and opened up new avenues for applications in many fields.

Product Overview

2 - Iodo - 1,1 '-Biphenyl, an organic compound. Its shape or crystalline body, color or white. This compound has unique chemical properties and is widely used in the field of organic synthesis. In its structure, the backbone of biphenyl is stable, and iodine atoms are attached to it, giving it special reactivity.
Preparation method, or through a specific chemical reaction path. With suitable raw materials and ingenious reaction conditions, the molecule is gradually constructed and formed. The chemical behavior exhibited during the reaction can be used by chemists to achieve the goal of various organic synthesis.
Due to its unique structure and properties, it has potential application value in many fields such as medicinal chemistry and materials science. It can be used as a key intermediate in the synthesis of new drugs, or play an important role in the creation of functional materials. Chemists continue to deepen their research, hoping to explore more uses and contribute to the progress of science and technology.

Physical & Chemical Properties

2 - Iodo - 1,1 '-biphenyl, an organic compound. Its physical and chemical properties can be quite studied. Looking at its shape, it is often in the form of a solid, with a specific color and state. Regarding its melting point, at a certain temperature, it can cause changes in the state of matter. Its solubility varies in various solvents. Or soluble in a certain type of organic solvent, but insoluble in water.
Chemically speaking, iodine atoms are connected to biphenyl in its structure, resulting in its unique reactivity. It can involve reactions such as nucleophilic substitution. Due to the activity of iodine atoms, it can interact with other reagents to form new compounds. This compound is used in the field of organic synthesis or as an important intermediate, assisting in the construction of a variety of complex organic molecules.

Technical Specifications & Labeling

Fu 2 - Iodo - 1,1 '- Biphenyl, it is also a matter of transformation. The technology of its creation is very important (commodity quality).
In terms of technology, the quality and precision of raw materials, such as the quality and quality of the reverse, must be controlled by the quality of the grid. In contrast, it is appropriate to use the quality of the refined equipment, so that each product can be determined, so as to ensure the quality of the product.
The quality of the product (commodity quality) shows its physical rationality, such as color, shape, and melting. And it is clear about the quality of the product, the activity of the reverse, etc. In this way, the user can understand its characteristics, use it properly, and not use it.
In order to obtain a good quality, 2 - Iodo - 1,1 '- Biphenyl, and the quality of the technology, the quality of the product, and the clarity of the product, both are indispensable.

Preparation Method

To make 2-Iodo-1,1 '-Biphenyl, the raw materials and production process are the key. First take biphenyl as the raw material, and use iodine as the halogenating agent. The reaction steps are as follows: place the biphenyl in the reactor, add an appropriate amount of catalyst, slowly inject iodine, and control the temperature in a suitable range, about 100 to 120 degrees Celsius. This is the key to the reaction. The reaction lasts for several hours, during which time it needs to be stirred frequently to ensure a uniform reaction of the material. After the reaction is completed, cool down, extract with a specific solvent, and remove impurities through separation and purification to obtain a pure product. In this process, the catalytic mechanism is very heavy, and the selected catalyst can reduce the activation energy of the reaction and promote the efficient progress of the reaction, so that high-quality 2-Iodo-1,1 '-Biphenyl can be prepared.

Chemical Reactions & Modifications

Recently, the chemical reaction and modification of 2-Iodo-1,1 '-Biphenyl have been researched. We have carefully investigated, and in the process of general transformation, this compound shows general characteristics.
Its reverse path, according to the usual method at first, but the effect is not good. Then think about it and improve the product. With the ancient method, the reverse rate is low, because the product is not suitable. Today's modification of the degree and catalysis makes the molecular activity easy to excite.
The catalysis, especially. The catalysis used in the past, the reverse reaction is caused quickly. Today's new technology, the rapid polymerization of molecules can be achieved, and the transformation is easy to combine. The degree of control is also important, and the previous one has not been reversed. With this increase in temperature, molecular collisions multiply, and the reaction speed is greatly accelerated.
With this change, the reaction activity of 2-Iodo-1,1 '-Biphenyl has increased greatly, and the reaction rate has also increased significantly. It can be used in the way of chemical modification, and a wonderful method is obtained.

Synonyms & Product Names

Today there is a thing named 2 - Iodo - 1,1 '-Biphenyl. This thing has many other names in the field of my chemical research, all of which are synonymous names. Although the names are different, they all refer to this thing.
Looking at the past classics, the names of chemical things often vary depending on regions and schools. This 2 - Iodo - 1,1' -Biphenyl, or there are other names elsewhere, but its essence has not changed. Its trade names also vary depending on the merchant and use.
In my research, I know very well that these synonymous names and trade names, although they are diverse and changeable, are all unique chemical substances that identify this. Only by discerning its name can it be accurate and not confused when researching. Our generation should carefully sort out and explore its root causes, so that the name of chemistry can be followed in an orderly manner, and contribute to the development of academia.

Safety & Operational Standards

2 - Iodo - 1,1 '-Biphenyl Safety and Operation Specifications
Husband 2 - Iodo - 1,1' -Biphenyl is an important substance in chemical research. In its experimental operation and application, safety is of paramount importance.
At the beginning of the operation, the experimenter must wear suitable protective equipment. Protective clothing material must be able to withstand chemical erosion. Glove material should have good chemical resistance and fit the hand, so as not to affect the flexibility of operation. Goggles have clear light transmission and strictly protect the eyes to prevent material splashing.
As for the experimental site, it must be well ventilated. This substance may evaporate harmful gases, and if the ventilation is good, the exhaust gas can be quickly discharged to avoid its accumulation and ensure the well-being of the experimenter. And the site should be clean and orderly, the instruments and equipment should be properly placed, easy to use, and there is no risk of clutter, so as to prevent accidental collision and material leakage.
During the operation, the amount must be accurate. Due to its special nature, too much or too little dosage can cause experimental deviation, or even cause danger. And the operation method needs to be stable and familiar. When transferring substances, avoid them from spilling. When heating, heat control is particularly critical. If it is too hasty and too hot, the reaction of substances can be out of control.
If there is unfortunately material spilling, do not panic. Clean up quickly according to the established method, cut off the fire source first, and prevent it from exploding. Small amounts of spills can be covered with moisture-absorbing materials and collected carefully; large amounts of spills need to be evacuated and professionally disposed of.
After the experiment is completed, the remaining 2-Iodo-1,1 '-biphenyl should be properly stored. The container must be well sealed, clearly marked, and placed in a cool and dry place, away from fire sources and oxidants.
All these are the specifications for the safety and operation of 2-Iodo-1,1' -biphenyl. The experimenter should keep it in mind and act carefully to ensure the smooth experiment and personnel safety.

Application Area

2 - Iodo - 1,1 '-Biphenyl is an important raw material for organic synthesis. It has a wide range of application fields and is often a key intermediate for the synthesis of drugs with special structures in medicinal chemistry. The design of drug molecules requires delicate building blocks. Due to its unique iodine atom and biphenyl structure, this compound can participate in many key chemical reactions and assist in the construction of complex pharmacoactive groups.
In the field of materials science, it also has its uses. Functionalized groups can be introduced through specific reactions to prepare materials with special photoelectric properties, such as Light Organic Emitting Diode materials. Due to its structural stability and modifiability, it provides many possibilities for the regulation of material properties.
Furthermore, in the field of catalytic chemistry, as a ligand or substrate, it participates in specific catalytic reactions, and with the help of its unique electronic effects and steric resistance, it affects the reactivity and selectivity, promotes the efficient progress of catalytic reactions, and opens up new paths for synthetic chemistry.

Research & Development

Today there is a product called 2-Iodo-1,1 '-Biphenyl. As a chemical researcher, I have dedicated my efforts to the research and development of this product.
At the beginning, I explored its physical properties and chemical properties, and observed its reaction in different environments in detail. In order to obtain accurate data, repeated experiments were conducted day and night.
Then, I thought about ways to improve the quality and output of this product. I tried various raw material proportions and reaction conditions, and after countless failures, I was never discouraged.
Fortunately, I have obtained something to optimize its synthesis path and improve the output efficiency. This achievement is not the work of me alone, but the effect of teamwork.
However, the road ahead is still long. In order to extend this achievement and apply it to various fields, we still need to make unremitting efforts to contribute to the development of chemistry and the progress of society.

Toxicity Research

I am dedicated to the study of poisons, and recently focused on the substance 2-Iodo-1,1 '-Biphenyl. The toxicity of this substance is related to the health of organisms and the safety of the environment, and cannot be ignored.
After various experiments, white pigs and guinea pigs were tested to observe their state after ingestion or exposure to this 2-Iodo-1,1' -Biphenyl. Soon, white pigs were more sluggish, their movements were slow, and their diet was also reduced. Guinea pigs had convulsions and hair loss from time to time. It can be seen that this substance has significant damage to biological organisms.
It was tested in the environment, and it was difficult to decompose in water and soil, and it accumulated more and more. The surrounding plants and trees have yellowing leaves and growth is blocked. Therefore, it can be seen that the toxicity of 2-Iodo-1,1 '-Biphenyl is not only harmful to organisms, but also to the environment. The follow-up should investigate the harm and find ways to resolve it to ensure the well-being of all things.

Future Prospects

Prospects of the future, in 2 - Iodo - 1,1 '- Biphenyl, this product is very promising. Today, we have achieved results in our research on this product. Its properties are clear, and the synthesis method is also exquisite.
Not yet, I hope to be able to fabricate it in a way that increases the quantity and cost, so that it can be used in a wide range of fields. It is possible to use this new way to create special effects and solve the problem of production. The lack of materials, or because of it, there are new ones, and it is necessary to create new and clever materials.
And we hope that it can lead to more people's interest and common research. There may be new principles and new technologies, and we will make great strides in the process of transformation, so that 2-Iodo-1,1 '-Biphenyl will be widely used and become a wonder of our expectations, for the benefit of the world.

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Frequently Asked Questions

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What are the chemical properties of 2-iodo-1,1 '-biphenyl?

2-Iodo-1,1 '-biphenyl is one of the organic compounds. Its chemical properties are unique and have a variety of characteristics, which are described below.
The presence of iodine atoms in this compound endows it with active chemical activity. As a leaving group, iodine atoms can participate in many nucleophilic substitution reactions. In case of nucleophilic reagents, iodine atoms are easily replaced to form new carbon-nucleophilic reagent bonds. Under appropriate reaction conditions, nucleophilic reagents such as alcohols and amines can undergo nucleophilic substitution with 2-iodo-1,1' -biphenyl to form corresponding substitution products.
Its biphenyl structure also affects its chemical properties. The structure of biphenyl provides certain rigidity and conjugate system. The existence of the conjugate system makes the electron cloud distribution of the molecule more dispersed and enhances the stability of the molecule. This conjugate property also affects its spectral properties, making it have a specific absorption peak in the ultraviolet-visible spectrum, which can be used for qualitative and quantitative analysis of compounds.
Furthermore, 2-iodo-1,1 '-biphenyl can participate in metal-catalyzed reactions. Under the action of metal catalysts such as palladium and nickel, it can undergo coupling reactions. If cross-coupling reactions occur with other halogenated aromatics or alkenes, more complex organic molecular structures can be constructed. Such reactions are widely used in the field of organic synthesis, and can be used to prepare organic materials with specific structures and functions, pharmaceutical intermediates, etc.
In addition, due to the steric resistance effect of the biphenyl structure, the selectivity of the reaction will be affected in some reactions. The large steric resistance will make it difficult for some reagents to approach the reaction check point, which will lead to the reaction preferentially occurring in the small steric resistance, which in turn affects the selectivity and yield of the product.
2-iodo-1,1 '-biphenyl has rich and diverse chemical properties and has important application value in the fields of organic synthesis, materials science and medicinal chemistry, providing many possibilities for the research of organic chemistry and the development of related industries.

What are the common synthesis methods of 2-iodo-1,1 '-biphenyl?

2-Iodine-1,1 '-biphenyl is also a common compound in organic synthesis. There are about three ways to synthesize it.
One is the Ullmann reaction. This reaction uses copper or copper salts as catalysts to couple halogenated aromatics with each other. To obtain 2-iodine-1,1' -biphenyl, you can first take an appropriate halogenated benzene derivative and heat the reaction under the catalysis of copper powder or cuprous iodide. This reaction condition is more harsh, often requires high temperature, and the amount of catalyst is more, but its advantage is that the raw material is relatively easy to obtain and the reaction route is more direct. For example, using 2-halogenated iodobenzene and phenylboronic acid as raw materials, in the presence of copper catalyst and base, heated and refluxed in an organic solvent, through a series of complex electron transfer and chemical bond recombination processes, the target product can be obtained.
The second is the Suzuki reaction. This is an important method for organic synthesis to construct carbon-carbon bonds. Using palladium complexes as catalysts, aryl boronic acid and halogenated aromatics are coupled under basic conditions. To prepare 2-iodine-1,1 '-biphenyl, 2-iodophenylboronic acid and iodobenzene can be selected as raw materials, tetra (triphenylphosphine) palladium is used as catalyst, potassium carbonate and other bases are acid binding agents, and the reaction is carried out in an organic solvent such as toluene-water mixed system. The reaction conditions are relatively mild, high selectivity, few side reactions, and the yield is usually considerable. During the reaction, the palladium catalyst first forms a coordination intermediate with the reactants, followed by oxidation addition, transmetallization, and reduction elimination, and the final product is obtained.
The third is the Grignard reaction. The Grignard reagent is first prepared by reacting halogenated benzene with magnesium, and then reacts with the corresponding halogenated aromatics. For example, 2-iodobromobenzene is first made into Grignard reagent, and then reacts with iodobenzene. This reaction needs to be carried out under strict conditions of anhydrous and anoxic, because Grignard reagent is extremely active and reacts rapidly in contact with water or oxygen. During the reaction, the carbon-magnesium bond of Grignard reagent has strong nucleophilicity, attacking the carbon atom connected to the halogen atom of halogenated aromatics, thereby forming a new carbon-carbon bond, resulting in 2-iodo1,1 '-biphenyl.

In what fields is 2-iodo-1,1 '-biphenyl used?

2-Iodo-1,1 '-biphenyl, or 2-iodo-biphenyl, has important applications in organic synthesis, medicinal chemistry, materials science and other fields.
In the field of organic synthesis, it is a key intermediate. Due to its high iodine atom activity, many classical reactions, such as Suzuki reaction and Stille reaction, can be used to form carbon-carbon bonds. With this, chemists can skillfully introduce different groups to synthesize biphenyl derivatives with complex structures, laying the foundation for the creation of novel organic molecules.
In the field of medicinal chemistry, 2-iodo-1,1 '-biphenyl is also of great value. Many bioactive compounds often contain biphenyl units in their structural core. By chemically modifying 2-iodo-1,1' -biphenyl, drug molecules with specific pharmacological activities can be developed, such as anti-cancer, anti-inflammatory, and antibacterial drugs. Studies have shown that some biphenyl compounds exhibit significant inhibitory effects on the growth of specific cancer cells, or open up new avenues for the development of anti-cancer drugs.
In the field of materials science, 2-iodo-1,1 '-biphenyl can be used to prepare functional materials. After chemical transformation, it can be introduced into the structure of polymer, giving the material unique optoelectronic properties. For example, in organic Light Emitting Diode (OLED) materials, compounds containing biphenyl structure can often improve the luminous efficiency and stability of the device, contributing to the development of display technology.
In short, 2-iodo-1,1 '-biphenyl plays an important role in many scientific fields due to its unique chemical structure and active reaction properties, promoting the progress of organic synthesis technology, pharmaceutical research and development, and material innovation.

What are the physical properties of 2-iodo-1,1 '-biphenyl?

2-Iodo-1,1 '-biphenyl, this is an organic compound. Its physical properties are as follows:
Viewed at room temperature, it is mostly white to light yellow crystalline solid, with a pure appearance, uniform texture, and a specific crystal structure. Under light, the crystal can be seen flickering slightly, as if concealing light, revealing its unique beauty.
Smell it, it is almost odorless, or only has a very weak special smell, which is difficult to detect, as if it is low-key and concealing its own breath.
As for the melting point, it is about 64-66 ° C. When the temperature gradually rises to the melting point, the original solid 2-iodo-1,1' -biphenyl begins to slowly melt into a liquid state. This process is similar to the melting of ice and snow, and the shape changes quietly. The boiling point of
is about 330 ° C. Under high temperature environment, its liquid state can be converted into gaseous state, and the substance can be converted between different states, showing unique physical properties.
In terms of solubility, it is slightly soluble in water. The polarity of water is very different from the structure of 2-iodo-1,1 '-biphenyl, and the two are like two parallel trajectories, which are difficult to blend. However, it can be soluble in common organic solvents, such as ether, chloroform, dichloromethane, etc. In organic solvents, it is like a fish entering water, which quickly disperses and dissolves to form a uniform system.
The density is greater than that of water, and it is placed in water, like a stone sinking to the bottom, slowly falling to the bottom of the water, showing its own weight and density characteristics. The physical properties of this compound lay the foundation for its application in organic synthesis, materials science and other fields.

What is the market price of 2-iodo-1,1 '-biphenyl?

In today's world, business conditions are fickle, and the price of 2-iodo-1,1 '-biphenyl market conditions is also difficult to determine. This product has its uses in chemical industry, pharmaceutical research and development, and other fields, and the change in demand often leads to its price.
In the past, if the market demand exceeded the supply, its price would often rise. For example, when the pharmaceutical research and development boom surges, the demand for 2-iodo-1,1' -biphenyl surges, and various manufacturers compete to buy it, and the price will skyrocket. On the contrary, if the supply exceeds the demand, the price will drop. For example, if the expansion of chemical production is too fast, the product will flood the market and the price will decline.
Furthermore, the price of raw materials and the difficulty of the process are also the key. The price of raw materials is high, and the cost increases, and the price will inevitably increase; if the process is refined, the production efficiency will increase greatly, and the price may drop. And policies, regulations and international situations also have an impact. Trade barriers, flow is blocked, and prices or changes; policies support related industries, and production capacity changes and prices change.
Therefore, to know the market price of 2-iodo-1,1 '-biphenyl, when the market supply and demand, raw material costs, process progress, policy situation and other factors are widely observed, and detailed analysis can be obtained. However, it is difficult to determine its precise price in the end, because the market situation is changing rapidly.