2 Iodo 1 Phenylbenzene
Iodobenzene

2-Iodo-1-Phenylbenzene

Fengxi Chemical

Specifications

HS Code

586639

Chemical Formula C12H9I
Molar Mass 276.104 g/mol
Appearance Solid
Color Off - white to light yellow
Odor Odorless
Melting Point 76 - 78 °C
Boiling Point 312.5 °C at 760 mmHg
Density 1.627 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform

As an accredited 2-Iodo-1-Phenylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - iodo - 1 - phenylbenzene packaged in a sealed, chemical - resistant bottle.
Storage 2 - iodo - 1 - phenylbenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent leakage and exposure to air and moisture. Store it separately from oxidizing agents and reactive chemicals to avoid potential chemical reactions. Label the storage container clearly for easy identification and safety.
Shipping 2 - iodo - 1 - phenylbenzene is shipped in accordance with chemical regulations. It's carefully packaged in suitable containers to prevent leakage. Shipment involves proper handling and transportation to ensure safety during transit.
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2-Iodo-1-Phenylbenzene
General Information
Historical Development
In the past, there were different people in the realm of transformation, and they studied a strange thing, named 2 - Iodo - 1 - Phenylbenzene. The study of things began with subtle thoughts, wanting to explore the wonders of material change. At the beginning, everyone did not know its nature and its use.
However, the researchers are persevering, and they move over the years, observing the rules of their reactions, and knowing the skill of their combinations. Or under the solitary lamp on a cold night, or in the heat of summer, they are all dedicated and have never been slack.
As the years pass, its power gradually becomes apparent. From the initial ignorance to understanding its characteristics, it can be used for all kinds of purposes. This 2 - Iodo - 1 - Phenylbenzene thing, then in the transformation, emerged, opened a new path for future generations, an unforgettable chapter in the history of Chenghua research, adding a touch of brilliance to the way of material exploration.
Product Overview
2 - Iodo - 1 - Phenylbenzene, this is an organic compound. Its molecular structure contains a benzene ring, and the iodine atom on the benzene ring is cleverly connected to the phenyl group.
Preparation of this compound often requires exquisite organic synthesis. It can precisely replace the specific hydrogen atom on the benzene ring by a specific halogenation reaction. During the process, the reaction conditions, such as temperature and catalyst, need to be carefully controlled in order to obtain the best yield and purity.
This compound is widely used in the field of organic synthesis. Or it can be used as a key intermediate to construct more complex organic molecular structures. With its activity of iodine atoms, it can react with many nucleophiles, expand the structural diversity of molecules, and lay the foundation for the creation of new organic materials and drugs. Its unique structure and properties have also attracted many chemical researchers to explore in depth, hoping to tap more potential application values.
Physical & Chemical Properties
2 - Iodo - 1 - Phenylbenzene is also an organic compound. Its physical and chemical properties are important for chemical research.
Looking at its physical properties, under normal temperature, it is mostly solid and has a specific color and state. Melting point and boiling point are the keys to characterize its physical properties. Melting point is the temperature at which a substance changes from a solid state to a liquid state. Boiling point is the critical temperature at which liquids turn into gases. These two can help researchers understand the state changes at different temperatures.
In terms of its chemical properties, iodine atoms are active and can participate in many chemical reactions. The existence of aromatic rings gives them the characteristics of aromatic compounds, which can perform reactions such as electrophilic substitution. Due to the synergistic effect of iodine and benzene ring in its structure, it is often an important intermediate in the field of organic synthesis, and has potential applications in drug development and material preparation. The investigation of its physical and chemical properties is the cornerstone of chemical synthesis and application, and is of great significance to the development of chemistry.
Technical Specifications & Labeling
Jinyan 2 - Iodo - 1 - Phenylbenzene This product, its technical specifications and identification (commodity parameters) are the key. To make this product, a specific method needs to be followed. First take an appropriate amount of benzene, introduce iodine atoms with subtle techniques, and the heat and dose need to be precisely controlled. The reaction environment is also strictly regulated, and factors such as temperature and humidity will affect the product.
In terms of identification, its chemical composition and physical properties should be detailed. Such as what color the appearance should be, melting point, boiling point geometry, and purity standards should be clearly marked. Among the commodity parameters, the quality index should be accurate, and the proportion of impurities contained should be strictly limited. In this way, this product can be made in line with technical specifications and accurately marked to meet the needs of all parties.
Preparation Method
In the process of making 2 - Iodo - 1 - Phenylbenzene, it is first necessary to clarify the raw materials. Benzene and iodobenzene are used as the basis, and the two are the main materials. The process of the preparation method is to mix benzene and iodobenzene in a special container and add a catalyst. This agent can promote the reaction speed.
The reaction steps are as follows: Control the temperature at a suitable degree, about one hundred or twenty degrees Celsius. After several hours, the two gradually react. During the reaction, pay attention to stirring to make the mixture uniform.
Its catalytic mechanism is that the catalyst activates the molecules of benzene and iodobenzene, reducing the energy barrier of the reaction and making it easier for the two to combine. After the reaction is completed, the product is purified by distillation to remove its impurities, and pure 2-Iodo-1-Phenylbenzene can be obtained. In this way, to obtain this product, the process needs to follow the steps and control the conditions to get the best effect.
Chemical Reactions & Modifications
Taste the way of chemical industry, endless changes, material transformation, the mystery is very good. Today there are 2-Iodo-1-Phenylbenzene this material, its exploration of chemical reactions and modifications, quite a bit can be said.
The chemical reaction of the husband, such as the combination of yin and yang, changes widely. 2-Iodo-1-Phenylbenzene, the reactions it participates in, or nucleophilic substitution, or addition elimination, all depend on its structural characteristics and external conditions. In the past, Fang's family, exploring its reaction mechanism, like tearing off cocoons, strives to understand its micro. In the regulation of reaction conditions, temperature, pressure, catalyst and other factors are carefully considered, hoping to promote its efficient conversion and obtain the required products.
As for the modification, chemists are trying their best to give it new properties. Or introduce functional groups to change its physical and chemical properties, or modify its structure to make it perform well in specific fields. Such as the strengthening of materials and the synergy of drugs, all depend on this.
As chemical researchers, we continue to study and explore 2-Iodo-1-Phenylbenzene more possibilities to benefit the progress of science and benefit the world.
Synonyms & Product Names
2 - Iodo - 1 - Phenylbenzene, also known as o-iodobiphenyl. Although ancient chemistry is not as developed as it is today, the name of the substance also has its origin. For our chemical researchers of the generation, exploring its synonyms shows the development of chemistry.
o-iodobiphenyl, its name depends on its structure. The benzene ring is connected, and one of its iodine atoms is adjacent to each other, so it has this name. However, in the past, or due to different regions and teachers, there are also different names.
Or there are people who call it by its properties and preparation methods. Although the years have passed, many old names are gradually fading, but still exploring the names of the past, such as digging treasures, can know the traces of previous exploration. Or the preparation was difficult at that time, the raw materials and steps used were different, and the names were also different. My generation should trace back to the source and seek the origin, in order to understand the wonders of chemical knowledge inheritance, and get the precious beads of past chemical research in the same name, adding color to today's research.
Safety & Operational Standards
2-Iodo-1-Phenylbenzene safety and operating standards
2-Iodo-1-Phenylbenzene, it is a very important chemical in organic synthesis. It is related to safety and operating standards and cannot be ignored.
When storing, it should be placed in a cool, dry and well-ventilated place. This is because the chemical is quite sensitive to environmental factors. Humidity or high temperature may cause its properties to change, or even cause danger. It must be kept away from fires and heat sources to prevent accidents. And it should be stored separately from oxidants and acids, and must not be mixed. The cover is easy to react with various substances due to its active chemical properties, which endangers safety.
When operating, operators must undergo special training and strictly abide by the operating procedures. Wear appropriate protective equipment, such as protective clothing, gloves and goggles. This is essential to protect people from harm. When taking it, the action should be steady and accurate to avoid spilling. If there is any accidental spilling, it should be dealt with immediately according to specific procedures. First absorb with inert materials, then collect it in a suitable container and dispose of it according to regulations. Do not discard it at will to avoid polluting the environment.
During the experiment, the ventilation equipment must be good. Due to 2-Iodo-1-Phenylbenzene or volatilization of harmful gases, if it accumulates indoors, it is very harmful to human health. And the reaction conditions need to be precisely controlled during operation. Parameters such as temperature and pressure are related to the success or failure of the reaction and safety. A slight error may cause the reaction to go out of control.
In short, when dealing with 2-Iodo-1-Phenylbenzene, we should follow the safety and operation standards in a rigorous and prudent manner to ensure the smooth operation of the experiment, the safety of personnel and the environment.
Application Area
2 - Iodo - 1 - Phenylbenzene, the application field of this substance is quite considerable. In the field of organic synthesis, it is often used as a key intermediate. With its unique structure, it can be derived through various chemical reactions, and many compounds with special properties can be derived.
Looking at the ancient books, the masters of organic synthesis often use this substance as a basis to expand the synthesis path. For example, through coupling reaction, it can be combined with various nucleophiles to construct complex aromatic structures. This is of great significance in drug development and materials science.
In drug development, it can be used as a starting material, or new active ingredients can be created to overcome difficult diseases. In the field of materials, through specific reactions, materials with unique optoelectronic properties can be prepared, contributing to the development of emerging materials.
The ancients said: "If you want to be good at something, you must first use your tools." 2 - Iodo - 1 - Phenylbenzene is like a sharp tool for organic synthesis and related application fields, pioneering and innovating for future generations, paving the way, leading the exploration of the unknown, and promoting science and technology.
Research & Development
In recent years, I have been in the field of organic synthesis, focusing on the study 2-Iodo-1-Phenylbenzene this thing. At the beginning, I observed its structure, which was exquisite and unique, and seemed to contain endless possibilities. Then I thought, if I can make good use of its properties, I may be able to open up new frontiers.
Therefore, I have tried all kinds of things, adjusting the temperature and pressure of the reaction, and choosing different reagents and catalysts. Although the process is difficult, it has been frustrated from time to time, but I have not changed my mind. After repeated research and debugging, I gradually obtained the best method.
As a result, the synthesis of 2-Iodo-1-Phenylbenzene has gradually matured, and the yield has steadily increased. And found that it has great potential in drug synthesis, material creation, etc. I believe that with time and in-depth research, it will be able to make its application more extensive, making progress in scientific research and industry, and adding new colors to the academic community and the industry. This is my vision and the goal of unremitting progress.
Toxicity Research
Toxicity study of 2-Iodo-1-Phenylbenzene
The 2-Iodo-1-Phenylbenzene, the chemical substances are also. The toxicity of today's research is of paramount importance to the researcher.
At first, take the chemical substances, such as rats and rabbits. In different amounts of 2-Iodo-1-Phenylbenzene. Or into the mouth, or skin, or suck it.

Day, observe the animal. Those who inhale it will suffer from respiratory diseases, asthma and cough.
As a result, 2-Iodo-1-Phenylbenzene toxic. Or harmful, or skin, or invasive breathing. Researchers should be careful, and when used, they must prevent it from being harmful.
Future Prospects
Today there is a thing called 2-Iodo-1-Phenylbenzene. We are researchers of chemicals, and we have hope for the future development of this thing.
This thing has unique properties and exquisite structure. Looking at its current situation, although it is already known, the future exploration space is vast. It is expected that in the future, it may shine in the field of organic synthesis. It may be the cornerstone of new materials and build a broad building of future technology.
We also think that in the road of drug research and development, we may be able to contribute to the conquest of difficult diseases and diseases by virtue of our own characteristics. Although the road ahead is long, we firmly believe that through unremitting research, 2-Iodo-1-Phenylbenzene will be able to show extraordinary potential, and it will be a brilliant stroke in the scientific picture of the future.
Where to Buy 2-Iodo-1-Phenylbenzene in China?
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Frequently Asked Questions

As a leading 2-Iodo-1-Phenylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemical structure of 2-iodo-1-phenylbenzene?
The chemical structure of 2-iodo-1-phenylbenzene, which is 2-iodo-1-phenylbenzene, can be regarded as two substituents on the benzene ring.
The main structure of this compound is a benzene ring, which is connected with a phenyl group at position 1 and an iodine atom at position 2 of the benzene ring. The benzene ring is a six-membered ring structure formed by six carbon atoms connected by special conjugated double bonds, which has unique stability and electron cloud distribution.
Phenyl is derived from the removal of one hydrogen atom from the benzene ring. As a larger substituent, it affects the electron cloud density and spatial structure of the benzene ring. The iodine atom is a halogen element with a large atomic radius and electronegativity. In 2-iodine-1-phenylbenzene, the presence of iodine atoms changes the electron cloud distribution on the benzene ring. Because the electronegativity of iodine is greater than that of carbon, the electron cloud of the benzene ring is shifted to the iodine atom.
From the perspective of spatial structure, the relative positions of phenyl and iodine atoms on the benzene ring determine the molecular spatial configuration. Due to the large size of the two, there will be a certain steric hindrance effect, which affects the molecular physical and chemical properties such as melting point, boiling point, solubility and chemical reactivity.
Overall, the chemical structure of 2-iodine-1-phenylbenzene exhibits unique properties and reactivity due to the interaction of phenyl ring, phenyl group and iodine atoms.
What are the main physical properties of 2-iodo-1-phenylbenzene?
2-Iodo-1-phenylbenzene is 2-iodo-1-phenylbenzene, also known as o-iodobiphenyl. Its main physical properties are as follows:
This substance is mostly white to light yellow crystalline powder, which is fine and powdery. It is uniform and delicate. Under normal temperature and pressure, it is stable and exists without special irritation, which is its apparent property.
Its melting point is between 63-67 ° C. When the ambient temperature rises to this range, 2-iodo-1-phenylbenzene gradually melts from solid to liquid. This melting point characteristic makes it possible to achieve phase transition under specific temperature conditions. The boiling point is around 328.8 ° C. At this high temperature, the substance is rapidly converted from liquid to gaseous state, showing obvious gasification phenomenon.
The density is about 1.56 g/cm ³, which indicates that its unit volume mass is relatively large, and it is in a specific range compared with the density of common organic compounds, reflecting the close arrangement of molecules.
2-iodine-1-phenylbenzene is extremely insoluble in water. Water is a polar solvent, and this compound is non-polar or weakly polar. According to the principle of "similar miscibility", the two are difficult to miscible. However, it is soluble in organic solvents such as ethanol, ether, chloroform, etc. Such organic solvents have non-polar or weakly polar characteristics, and are similar in structure to 2-iodine-1-phenylbenzene, so they can be mutually soluble. This solubility makes it possible to choose a suitable solvent for dissolution, reaction or separation in organic synthesis and related experimental operations.
What are the common applications of 2-iodo-1-phenylbenzene in organic synthesis?
2-Iodo-1-phenylbenzene, or 2-iodo-1-phenylbenzene, is widely used in organic synthesis.
One of them is often the key raw material for building carbon-carbon bonds. For example, in the Suzuki coupling reaction, this compound can successfully form biaryl compounds with aryl boric acid with the help of palladium catalyst and base. This reaction condition is mild and selective, opening up a smooth path for the synthesis of polyaryl compounds, which is of great significance in the fields of medicinal chemistry and materials science. When preparing some organic materials with special photoelectric properties, this method is often used to synthesize biaryl materials with exquisite structures and unique properties by reacting 2-iodine-1-phenylbenzene with specific arylboronic acids.
Second, in metal-catalyzed cyclization reactions, 2-iodine-1-phenylbenzene has also emerged. With suitable metal catalysts and ligands, it can undergo intramolecular cyclization to generate complex cyclic compounds. For example, under specific conditions, it can be cyclized to construct compounds containing benzo heterocyclic structures. Such compounds are often important intermediates in the total synthesis of natural products and the development of new drugs.
Third, in the nucleophilic substitution reaction, the iodine atom of 2-iodine-1-phenylbenzene is active and easily replaced by various nucleophilic reagents. When the nucleophilic reagents are alcohols, amines, etc., ether and amine derivatives can be generated respectively. This provides convenience for the introduction of different functional groups in the design of organic synthesis routes, enriches the structural diversity of compounds, and is widely used in the synthesis of fine chemicals.
What are 2-iodo-1-phenylbenzene synthesis methods?
To prepare 2-iodo-1-phenylbenzene, there are two methods. First, iodobenzene and phenylboronic acid are used as raw materials, palladium is used as catalyst, and with the help of alkali, Suzuki coupling reaction is carried out. The reaction is as follows:
iodobenzene and phenylboronic acid, when palladium catalyzes and alkali participates, the two combine to form 2-iodo-1-phenylbenzene. This reaction condition is mild, the selectivity is good, and the yield is also quite high. The palladium catalyst used has excellent activity and selectivity, which can make the reaction proceed efficiently. The addition of base can promote the formation of reaction intermediates and speed up the reaction rate.
Second, o-iodoaniline is used as the starting material, and then reacted with benzene through diazotization. The specific steps are: o-iodoaniline first interacts with sodium nitrite and acid to form a diazonium salt. This diazonium salt is active and can react with benzene under the catalyst of copper salt to obtain 2-iodo-1-phenylbenzene. During the diazotization reaction, the temperature, the amount of acid and the dripping speed of sodium nitrite need to be precisely controlled to avoid side reactions. In the arylation reaction, the type and amount of copper salt catalyst have a great impact on the reaction.
These two methods have their own advantages and disadvantages. Although the Suzuki coupling reaction has mild conditions and high yield, the cost of palladium catalyst is high; the diazotization-arylation method is common in raw materials, but the reaction steps are slightly complicated and require fine operation to obtain the ideal yield.
What are 2-iodo-1-phenylbenzene storage conditions?
2-Iodo-1-phenylbenzene is o-iodobiphenyl. This substance is more active in nature and its storage conditions are very critical.
Because of its iodine-containing atoms, it is easy to cause reactions when exposed to light or heat, causing it to deteriorate. Therefore, when stored in a cool place, away from direct sunlight, the energy in sunlight will promote its chemical reaction and shorten the storage period.
At the same time, it needs to be placed in a dry environment. Water vapor in the air or reacts with iodine-containing organic matter, causing reactions such as hydrolysis of o-iodobiphenyl, which affects the purity and quality. A desiccant can be used to maintain a dry storage environment.
Furthermore, it should be stored in a sealed container to prevent contact with air. Oxygen and other components in the air may react with o-iodiphenyl, sealing can block air from entering and reduce the chance of reaction.
When storing, it should also be kept away from fire and heat sources. This organic substance is flammable, and it is heated or causes combustion or even explosion, which threatens safety.
And it needs to be stored separately from the oxidant. Due to its structural characteristics, it is easy to react violently when encountering the oxidant. Storage separately can avoid danger.
When storing 2-iodo-1-phenylbenzene, it should be sealed and stored in a cool and dry place, away from fire and heat sources, and isolated from the oxidant, so as to ensure its quality and stability.