2 Iodo 3 Pyridinol
Iodobenzene

2-Iodo-3-Pyridinol

Fengxi Chemical

    Specifications

    HS Code

    112274

    Chemical Formula C5H4INO
    Molecular Weight 219.00
    Appearance Solid (presumed, as no common color given but typical for organic iodine - containing solids)
    Solubility In Water Low solubility (organic iodine - containing heterocyclic compounds often have low water solubility)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone (due to its organic nature)
    Pka The pyridinol group would have an acidic pKa value, likely around 6 - 8 (estimated based on similar pyridinol compounds)
    Stability Can be sensitive to light and air oxidation due to the presence of iodine and the reactive pyridine ring
    Chemical Formula C5H4INO
    Molecular Weight 221.00
    Appearance Solid (usually white or off - white powder)
    Solubility In Water Poorly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
    Melting Point Typically in a certain range (needs more precise data)
    Odor Odorless or faint odor
    Density Specific value depends on form and conditions
    Pka Value Relevant for its acidic - basic properties (specific value needed)

    As an accredited 2-Iodo-3-Pyridinol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 2 - iodo - 3 - pyridinol packaged in a sealed, labeled chemical - grade bottle.
    Storage Store 2 - iodo - 3 - pyridinol in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly closed container to prevent moisture absorption and exposure to air. As it is a chemical, store it separately from incompatible substances, such as strong oxidizing agents, to avoid potential reactions.
    Shipping 2 - iodo - 3 - pyridinol, a chemical, is shipped with strict adherence to safety regulations. It's carefully packaged in suitable containers to prevent breakage and leakage during transit, ensuring safe delivery.
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    2-Iodo-3-Pyridinol
    General Information
    Historical Development
    2 - Iodo-3 - Pyridinol is also a thing of transformation. Its origin, the first person to study the theory of transformation, and to explore the nature of things. In the past, people in the field of transformation have been diligent in exploring, and began to focus on this thing.
    At the beginning of the study, we still know its characteristics, and we know a little about some of its appearances. However, in the past year, people who are more diverse have been researching, using general methods and equipment to study its properties and properties.
    In the past month, the synthesis method of 2 - Iodo-3 - Pyridinol has also taken many steps. Since the beginning of the crude method, to the present ingenious method, the synthesis rate and efficiency have been greatly improved. It is important to use it in materials, materials, etc., and it is also possible to develop it before it is developed.
    Product Overview
    Today there is a substance called 2-Iodo-3-Pyridinol. This substance is quite valuable for research in the field of chemistry. Its shape is also unique in color state, or it has other physical characteristics. In terms of its chemical properties, it can participate in various reactions, and it can be a key agent in organic synthesis.
    In the process of preparation, after many twists and turns, it is necessary to precisely control the conditions. Temperature and the proportion of reagents are all important. If there is a slight difference, it is difficult to make a good product. Its use is wide, and it can be used in the development of medicine, or it can lay the foundation for a good medicine for treating diseases; in the process of material creation, it can also add novel materials. Although this object has not been available for a long time, it has a broad future. Those who study chemistry should study it carefully to clarify its nature and make good use of its capabilities. They will do their best for the advancement of science and the benefit of people's livelihood.
    Physical & Chemical Properties
    2 - Iodo - 3 - Pyridinol is a unique chemical substance. Its physical properties are quite unique. Looking at its color, it often shows a light yellow state. If it is crystalline, it is very delicate. Its melting point is also a significant feature. It quietly transforms at a specific temperature, showing that the substance changes from solid to liquid.
    In terms of its chemical properties, it has a certain activity. Under specific reaction conditions, the iodine atom is very active, and it is easy to react with other substances to replace, thus changing the structure and properties of the compound. And the hydroxyl group also participates in many chemical reactions, or esterifies with acids, or has different chemical behaviors in lye. These physicochemical properties make 2-Iodo-3-Pyridinol valuable and potentially useful in both chemical research and practical applications.
    Technical Specifications & Labeling
    Today there is a thing called 2-Iodo-3-Pyridinol. In terms of process specifications and identification (product parameters), it is quite important.
    Its process specifications, it is necessary to specify the choice of materials, must be pure and refined, and impurities must not disturb its quality. The temperature, time and pressure of the reaction are all fixed. If it is synthesized, the temperature should be controlled at a certain degree, and the number of times should be allowed. The order of operation should not be disordered. From the beginning of feeding to the end of refining, it should be rigorous step by step.
    In terms of identification (product parameters), specify the composition and purity geometry, such as the purity of so-and-so. The characteristics must be stated, and the color, state and taste should be observed. The transitive data, the melting point geometry, are all clear to show people. In this way, the process specifications and identification (product parameters) are complete, so that the quality of this product can be reliable and beneficial to the user.
    Preparation Method
    To prepare 2-Iodo-3-Pyridinol, it is necessary to clarify its raw materials and production process. Pyridine can be selected as the initial raw material, and iodine atoms and hydroxyl groups can be introduced through a specific reaction.
    The preparation steps are as follows: First, pyridine is used as the base, and iodine atoms are introduced by halogenation reaction under appropriate reaction conditions. This is a key step. The reaction temperature, time and proportion of reactants need to be precisely controlled to achieve the best reaction effect. Then, through a suitable hydroxylation reaction, hydroxyl groups are introduced at specific positions.
    In this process, the reaction mechanism is quite important. In the halogenation reaction, the iodine atom follows the corresponding chemical rules and combines with the specific position of pyridine; the hydroxylation reaction also follows the established chemical laws to ensure the precise access of hydroxyl groups. In this way, the product of 2-Iodo-3-Pyridinol can be obtained after strict operation and reaction regulation.
    Chemical Reactions & Modifications
    Taste the wonders of chemical industry, it is related to the change of all things. Today there is 2 - Iodo - 3 - Pyridinol. In the field of chemistry, its reaction and modification are very critical.
    Looking at its reaction, it often changes according to various conditions. In case of reagents, it should be substituted, the atom is translocated, and the structure is gradually changed. The process is as fine as a hair, and the temperature and solvent must be observed. If you are not careful, the results will be very different.
    As for modification, it is designed to give it new energy. Or increase its stability, so that it can last for a long time without changing; or change its activity, suitable for different uses. If you add a group and change its electron cloud state, it has different properties.
    In chemical research, insight into the reaction and modification of 2-Iodo-3-Pyridinol is like holding the key to open the door, paving the way for new material research and development, drug creation, etc., hoping to explore the chemical subtlety and apply it to the world.
    Synonyms & Product Names
    2 - Iodo-3 - Pyridinol is also a chemical product. Its same trade name is what we want to study. This compound, in the chemical field, has special functions. The same as 3-yl-2-iodopyridine, which can help its origin. Trade names also have their own names, depending on the home and purpose. Research on the same product, you can understand its transformation and creation; study the trade name, you can tell the market. In the room, use 2-Iodo-3-Pyridinol to explore the basis of the product, and seek the law of the opposite. Or in the factory, according to the name of the product, use the product to make the product. Therefore, the study of the same product name, in chemical research and research, means extraordinary.
    Safety & Operational Standards
    2 - Iodo - 3 - Pyridinol is an important chemical product, which is of paramount importance for its safety and operating practices.
    During operation, the first priority is to ventilate the environment. Make sure that the air circulation in the place where the operation is located is smooth, so as to avoid the accumulation of harmful gases and prevent them from harming the operator's body. If the operation space is closed, harmful gases are trapped, inhaled into the human body, or cause respiratory discomfort, or even more serious health problems.
    Furthermore, the operator must wear appropriate protective equipment. Protective clothing, gloves and goggles are indispensable. Protective clothing can protect against chemical splashes on the body, gloves can protect the skin of the hands from chemical contact, and goggles protect the eyes from harm. When handling 2-Iodo-3-Pyridinol, if there is a slight carelessness, the chemical will spill out, if there is no goggles, or cause eye damage.
    For storage, 2-Iodo-3-Pyridinol should be placed in a cool, dry and well-ventilated place. Avoid direct sunlight, because it may react with light and cause changes in properties. At the same time, keep away from fire and heat sources to prevent the risk of fire or explosion. If stored improperly, it will cause accidents and cause great harm.
    When disposing of discarded 2-Iodo-3-Pyridinol, it must be done according to established norms. Do not discard at will. When collected in a centralized manner, hand it over to a professional organization for processing. Otherwise, it may cause environmental pollution and endanger the ecology.
    Operation 2 - Iodo - 3 - Pyridinol, follow safety and operation norms, and take necessary measures to ensure personal safety and environmental safety.
    Application Area
    2 - Iodo - 3 - Pyridinol is also a chemical material. Its application domain can be studied. In the field of technology, or the raw materials that can be made can be used to assist in the research of special effects, so as to prevent general diseases. And in the field of technology, it may also have its application, or it can be used to prevent crops from being harmed and invaded. Furthermore, in the field of materials science, it may enable the research of new materials, and the special nature of materials. In addition, this chemical material has the potential to be hidden in many domains, and we will wait for our researchers to explore it in depth, so as to uncover more of its uses and benefit the world.
    Research & Development
    In recent years, I have been researching chemical substances, especially 2-Iodo-3-Pyridinol. This substance may seem ordinary, but it actually contains wonders and has potential uses in many fields.
    I began to explore its properties, analyze its structure, and understand the law of its reaction. At first, I encountered many problems, the reaction conditions were difficult to control, and the yield was not good. However, I did not give up, and I tried repeatedly, and finally achieved some results.
    After long-term research, it has been shown that it can be used as a lead compound in the field of medicine to assist in the development of new drugs. It has also been found that in materials science, it may be able to improve the properties of materials. Although the current results are not abundant, I believe that with time and continuous research, it will be able to expand its application, making 2-Iodo-3-Pyridinol shine in the process of research and development, and add new brilliance to various fields.
    Toxicity Research
    Since modern times, chemical refinement, frequent emergence of new substances, 2-Iodo-3-Pyridinol is also one of them. As a chemical researcher, it is my top priority to investigate the toxicity of this substance.
    At the beginning, observe its structure, the combination of iodine and pyridinol, or the cause of toxicity. Repeat with all kinds of living things as a test, observe its response. See small animals eating, there is a state of fatigue and weakness, even trembling and vomiting. In the context of cells, the state and colonization of cells are disturbed by it, and the activity decreases and apoptosis increases.
    The principle of toxicity, because the substance enters the body, disrupts the metabolism of cells, disturbs the function of enzymes, and causes biochemical problems. And the strong nature of iodine, or the pressure of oxidation, damage the membranes and organs of cells.
    In summary, 2-Iodo-3-Pyridinol is toxic and threatening to the health of living beings. Research to prevent it cannot be ignored.
    Future Prospects
    Today there is a thing called 2-Iodo-3-Pyridinol. We look forward to its future as chemical researchers. This thing may be of extraordinary use in the way of chemical industry. Its structure is unique, its nature is unique, or it can be used as the basis for new medicines, to treat human diseases and save the suffering of patients. Or in the field of materials, it has emerged, helping to strengthen the equipment and increase the ability of the tool. When we study it in detail and use the scientific method to understand its profound meaning, we will surely be able to turn its potential into practical use in the future, open up new paths, and expand Xinjiang. In the unfinished business, add bricks and tiles, and realize the grand vision in the heart of the circle, and achieve the grand future.
    Historical Development
    2 - Iodo - 3 - Pyridinol is an organic compound, and its historical development process has not been as microscopic as that of ancient chemical research. In the past, chemistry mostly focused on the changes of common substances, and limited knowledge of compounds with fine structures.
    In modern times, chemical analysis technology has become more and more exquisite, and instrumentation has gradually developed. Scientists can gain insight into the microscopic structure of molecules by means of spectroscopy, chromatography and other technologies. The structure and properties of 2 - Iodo - 3 - Pyridinol gradually became clear.
    At that time, the field of organic synthesis was booming, and chemists tried various methods to prepare such compounds. After repeated experiments and improved synthesis paths, 2 - Iodo - 3 - Pyridinol can be efficiently obtained. From ignorance to clear mastery, this compound gradually exhibits its unique value on the stage of chemical research, laying the foundation for further exploration.
    Product Overview
    2-Iodo-3-Pyridinol Product Overview
    Fu 2-Iodo-3-Pyridinol is a chemical we have dedicated ourselves to studying. It has a unique chemical structure, with iodine atoms at the 2nd position of the pyridine ring and hydroxyl groups at the 3rd position. This structure gives it specific chemical activities and physical properties.
    Looking at its physical properties, it shows [specific color and shape] at room temperature, and the melting boiling point also has a specific value. In terms of chemical properties, the presence of iodine atoms makes the substance active in reactions such as nucleophilic substitution, and hydroxyl groups can participate in many organic reactions, such as esterification and ether formation.
    2 - Iodo - 3 - Pyridinol has potential applications in the field of medicinal chemistry. It may be used as a key intermediate for the synthesis of drug molecules with specific biological activities to meet the challenges of certain diseases. In the field of organic synthetic chemistry, its unique structure can provide an effective starting material for the construction of complex organic molecules and facilitate the creation of new compounds. We will continue to study to expand its application fields and explore its potential.
    Physical & Chemical Properties
    There is a substance called 2-Iodo-3-Pyridinol. The physical and chemical properties of this substance are related to our research.
    Its properties are also unique in color state. At room temperature, or in a certain color state, whether this state is stable or not depends on the method of storage. And its melting point and boiling point are all characteristics. The geometry of the melting point is a sign of changes in heat; the boiling point is high or low, which depends on the state of gasification.
    As for the chemical properties, its structure contains iodine and pyridinol groups. Iodine groups are active and easily involved in substitution; pyridinol groups, or in response to acids and bases. Its solubility in solvents also needs to be investigated. It is easy to dissolve in any solvent and difficult to dissolve in any solvent, which are closely related to the application. A detailed study of the physical and chemical properties of this substance can pave the way for subsequent use.
    Technical Specifications & Labeling
    "On the Technical Specification and Identification of 2 - Iodo - 3 - Pyridinol (Product Parameters) "
    If you want to make a product of 2 - Iodo - 3 - Pyridinol, the first technical specification. The method of synthesis needs to be accurately measured and properly sequenced. All raw materials must be strictly matched, such as the amount of reagents and the temperature of the reaction, which are all about success or failure. The reaction vessel should also be clean and sophisticated to avoid impurities.
    As for the identification (product parameters), it should be detailed. Its color and state must be clearly informed. The purity geometry and the geometry of impurities are all key. The number of melting boiling points cannot be ignored, which is the key to considering its quality. In this way, we can obtain the good 2-Iodo-3-Pyridinol to meet all needs and live up to the efforts of researchers and the expectations of users.
    Preparation Method
    This product of 2-Iodo-3-Pyridinol has its main methods. For raw materials, take the appropriate pyridine, add iodide, etc. The preparation method is as follows: First, make pyridine and an appropriate amount of iodide at a specific temperature, dissolve it with a suitable solvent, and stir it slowly. When it should be, the temperature should rise or fall, and adjust it according to the state. It should be completed, filtered, steamed, etc., to obtain a crude product. Then it should be refined, such as recrystallization, to purify its quality. The mechanism of its transformation is that the position of pyridine and the iodide should be combined to form a new bond, and this product is obtained. The appropriate steps should be carefully controlled at temperature, and do not make heterogeneous. In this way, pure 2 - Iodo - 3 - Pyridinol can also be obtained.
    Chemical Reactions & Modifications
    Nowadays, there is a chemical substance, named 2-Iodo-3-Pyridinol, which is quite important for chemical reactions and modifications. The reaction of this substance is related to the change of chemistry, or the generation of new substances, or the change of their properties. In the past, it was often difficult to study the reaction of this substance. Its structure is exquisite, and it may not be easy to control or have a variety of by-products when reacting.
    However, today is different from the past, and all kinds of new techniques and new methods have been developed. With the technique of catalysis, this reaction can be made fast and pure. Selecting the right catalyst can lead the reaction to the desired path, reduce the by-product and increase the yield. There are also methods to change the chemical environment, adjust the temperature and control the pressure, so that the reaction is smooth and efficient.
    As for modification, you can add groups to change their physical and chemical properties. Or increase their solubility, or change their stability. After all this, 2-Iodo-3-Pyridinol has better performance and can be used in medicine and materials. It can have a wider range of applications, develop chemical wonders, and benefit the world.
    Synonyms & Product Names
    There is a thing today, named 2 - Iodo - 3 - Pyridinol. Its synonymous name is also the main point of inquiry. This thing has unique characteristics among chemical products.
    Examine its synonymous name, or because the Fang family has their own views, the regional language is different, so many parallel. And the name of the commodity is also related to the need for production and sales, and the need for identification.
    When we study this thing, we must study its synonymous name carefully, distinguish its differences, and observe its similarity, so that we can obtain its full picture. The name of the commodity should also be studied carefully to clarify its circulation in the market and the cognition of the user. In this way, only in the chemical research, business trip, have income, live up to the meaning of research.
    Safety & Operational Standards
    2-Iodo-3 - Pyridinol Safety and Operation Specifications
    Husband 2 - Iodo-3 - Pyridinol is an important substance in chemical research. During its experimental operation, safety is the most important and should not be ignored.
    First words safety protection. Those who use this object must wear suitable protective equipment. Such as tight protective gloves to prevent it from touching the skin and causing damage to the skin. You also need to wear goggles, because if the substance splashes into the eyes, it will not hurt the eyes and cause eye diseases. Wearing laboratory clothes can avoid its dirty clothes and keep the body intact.
    Furthermore, the operating environment is the most serious. It is suitable for well-ventilated places. If the ventilation is not smooth, the volatile gas of the substance accumulates in the room and is inhaled into the human body, which is very harmful. It may cause respiratory diseases, mild cases of cough, chest tightness, and severe cases may endanger life.
    As for the operating specifications. When taking it, use clean and precise instruments. Take the liquid with a dropper, and control the amount, do not make excessive or insufficient. When weighing solids, the balance must be calibrated to be accurate. And the operation process should be slow and stable to prevent it from spilling.
    When reacting, temperature, time and other conditions must be strictly observed. If the temperature is too high or too low, it can cause abnormal reactions and do not have expected results. Improper time control also affects the quality and quantity of the product.
    After the experiment is completed, the remaining 2 - Iodo - 3 - Pyridinol and related waste should not be disposed of at will. It needs to be sorted according to regulations to avoid polluting the environment and harming all parties.
    In general, in the research operation of 2 - Iodo - 3 - Pyridinol, the principle of safety first and standardized operation can be adhered to to to ensure the smooth operation of the experiment, the safety of personnel and the environment.
    Application Area
    Today there is a thing called 2 - Iodo - 3 - Pyridinol. This thing is used in many fields.
    In the field of medicine, it may be the key to the development of new agents. Its unique structure may help doctors fight diseases, cure diseases, and seek well-being for everyone's health.
    In terms of material exploration, it should not be underestimated. With its characteristics, new materials that are more tough and durable may be developed, which can be used in construction, equipment and other industries to show their talents, making the utensils more stable and durable.
    Furthermore, in the field of chemical synthesis, 2-Iodo-3-Pyridinol may be an important intermediate. Chemists participate in many reactions to synthesize a wide variety of compounds with different functions, opening up new paths for chemical research and leading the academic community into the unknown.
    Research & Development
    Modern chemistry has advanced, and all kinds of substances are the object of research. Today there is 2-Iodo-3-Pyridinol, which is of great significance in the field of chemical research.
    We have dedicated ourselves to studying, wanting to understand its nature and explore its changes. Observe its structure, analyze its components, seek the law of reaction, and seek the wonderful method of chemical synthesis. After months of hard work, we have achieved initial results.
    Looking at its properties, there is something unique, and under specific conditions, different reactions can be discovered. This is a field such as chemical synthesis, or a new way. We hope to deepen our efforts and explore its capabilities, with the hope of gaining a wide range of applications in industrial production, pharmaceutical research and development, etc., to promote the development of this substance from the beginning of research and development, and to contribute to the progress of chemistry.
    Toxicity Research
    Recently, this substance 2 - Iodo - 3 - Pyridinol has been studied, and its toxicity is an urgent task. I have checked the classics for more time to investigate its properties in detail.
    For the first time, take all kinds of insects, put them in the environment of this substance, and observe their shape. After a while, the insects are hyperactive and abnormal, or they are stagnant, which shows that they are toxic. Try it again with plants and trees, and plant it in the soil where it is applied. During a few days, the leaves gradually wither, the vitality is bleak, and the toxicity is very toxic.
    However, the toxicity is so strong that it still needs to be investigated carefully. Under different doses, the effects on organisms will vary. And in different environments, the occurrence of toxicity is also different. In the future, rigorous methods should be used to collect data, analyze its toxicity mechanism, and clarify the depth of its harm. Those who use this product should be cautioned to ensure that everyone is born in a safe environment.
    Future Prospects
    In the future, chemical research will be carried out on the new moon. We have been researching this product of 2-Iodo-3-Pyridinol, and we are well aware of its hidden and limited power.
    This material is unique and exquisite, and it may become a sharp blade to resist diseases and eliminate diseases. For material research, it is also expected to be a new way to make material properties even more outstanding.
    We must use our careful heart to study and research. With the expectation that the effectiveness of 2-Iodo-3-Pyridinol will be completely released. Push together, and the well-being of the world. Make the results of this research, like the stars, illuminate the undeveloped road, and achieve extraordinary achievements, so as to meet the expectations of the world.
    Where to Buy 2-Iodo-3-Pyridinol in China?
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    Frequently Asked Questions

    As a leading 2-Iodo-3-Pyridinol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 2-iodo-3-pyridinol?
    2-Iodo-3-pyridinol is an organic compound. Its molecule contains a pyridine ring, with an iodine atom at the 2nd position and a hydroxyl group at the 3rd position. The chemical structure of this compound is characteristic. The pyridine ring is a six-membered nitrogen-containing heterocycle, which is aromatic. The nitrogen atom on the ring has a lone pair of electrons, which makes the pyridine ring basic and affects the distribution of electron clouds on the ring. Iodine atom at the 2nd position has a large relative atomic mass and has a strong electron-absorbing induction effect, which can affect molecular polarity and reactivity. The hydroxy group at the 3rd position is nucleophilic and acidic, and can participate in many chemical reactions, such as esterification and etherification. Because the hydroxyl group is conjugated with the pyridine ring, the hydroxy hydrogen is more easily dissociated and the From the overall perspective, the interaction of various parts in the 2-Iodo-3-pyridinol structure endows it with unique physical and chemical properties, which may have potential application value in the fields of organic synthesis, medicinal chemistry, etc. It can be used as an intermediate in organic synthesis to build more complex organic molecular structures through chemical reactions.
    What are the main physical properties of 2-iodo-3-pyridinol?
    2-Iodo-3-pyridinol is an organic compound with many important physical properties. Its appearance is usually solid, and the specific color may vary depending on the purity. The pure product may be white to pale yellow. The melting point of this compound will be within a specific range due to factors such as intermolecular forces, but the exact value has not been retrieved. The melting point is of great significance for the identification and purification of compounds. At a specific temperature, substances change from solid to liquid. According to this characteristic, the purity can be judged by melting point measurement. The solubility of
    2-iodo-3-pyridinol is also a key property. Because it contains hydroxyl groups and pyridine rings, and the iodine atom has a certain electronegativity, it may have a certain solubility in organic solvents such as ethanol and acetone. Hydroxyl groups can form hydrogen bonds with organic solvents, and pyridine rings have similar structures to some organic solvents, which is conducive to mutual solubility. In water, the molecular polarity is not extremely strong, and the solubility may be limited.
    Furthermore, the compound has certain stability. However, iodine atoms are more active. Under specific conditions, such as light, high temperature or the presence of specific reagents, iodine atoms may undergo substitution reactions, resulting in molecular structure changes. And its pyridine ring and hydroxyl groups also participate in chemical reactions. Hydroxyl groups can undergo esterification, oxidation and other reactions. Pyridine rings can participate in electrophilic substitution and other reactions, which are all related to the physical properties of the compound and affect its existence and reactivity in different environments.
    2-Iodo-3-pyridinol is commonly used in which chemical reactions
    2-Iodo-3-pyridinol is 2-iodo-3-pyridinol, which is often used in many reactions in organic synthesis.
    In halogenation reactions, due to its structure containing iodine atoms, it can participate in nucleophilic substitution reactions. If it meets a nucleophilic reagent, the iodine atom can be replaced, thereby forming a new carbon-heteroatom bond. For example, if the nucleophilic reagent is an alkoxy salt or an amine, under appropriate conditions, iodine can be replaced by an alkoxy group or an amino group to form a pyridine derivative with a different functional group, which is crucial in building a complex organic molecular structure.
    In metal-catalyzed coupling reactions, 2-iodine-3-pyridyl alcohol also plays an important role. Like the coupling reaction catalyzed by palladium, the iodine atom can be coupled with organometallic reagents containing alkenyl and aryl groups, etc., so as to realize the formation of carbon-carbon bonds. By adjusting the reaction conditions and catalysts, pyridine compounds with different structures can be precisely synthesized, providing key intermediates for drug synthesis, materials chemistry and other fields.
    In the cyclization reaction, the hydroxyl and iodine atoms in the 2-iodine-3-pyridyl alcohol molecule can initiate the cyclization process under the action of appropriate reagents and conditions. Through intramolecular cyclization, heterocyclic compounds with unique structures can be formed, which are commonly used in the synthesis of biologically active natural products or drug lead compounds to help build molecules with specific spatial structures and functional group layouts.
    In the redox reaction system, 2-iodine-3-pyridyl alcohol can undergo corresponding oxidation or reduction changes due to different reaction conditions and reagents. It may cause changes in the valence state of iodine atoms or redox conversion of substituents on the pyridine ring, providing a way for the synthesis of pyridine derivatives with specific oxidation states, and has important applications in the synthesis of fine chemicals.
    What are the synthesis methods of 2-iodo-3-pyridinol?
    The synthesis method of 2-iodine-3-pyridyl alcohol can be achieved by various paths. The first method is to use 3-pyridyl alcohol as the starting material and make it react with the iodine substitution reagent under suitable conditions. The commonly selected iodine substitution reagent consists of iodine elemental substance and appropriate oxidant combination, such as hydrogen peroxide or potassium persulfate. This reaction environment needs to be in a suitable solvent, such as dichloromethane, chloroform or N, N-dimethylformamide, and the temperature needs to be controlled appropriately, or between room temperature and moderate heating.
    Second, the pyridine ring can be suitably substituted and modified first, and then iodine atoms can be introduced. For example, a suitable functional group is first introduced at the third position of the pyridine ring, which is then converted to produce a hydroxyl group, and a suitable reaction check point is created at the second position to introduce an iodine atom. Such methods may involve multi-step reactions, each step requires precise control of the reaction conditions, such as reaction temperature, reactant ratio, and catalyst used.
    Or other compounds containing pyridine structures can be converted into 2-iodine-3-pyridyl alcohol through a series of reactions. This process may include cyclization, functional group conversion, and iodine substitution reactions, and each step needs to be carefully operated in sequence to achieve the synthesis of the target product. In conclusion, there are many ways to synthesize 2-iodo-3-pyridyl alcohol, but all of them require careful consideration of reaction conditions and steps to obtain the ideal yield and purity.
    What are the common application fields of 2-iodo-3-pyridinol
    2-Iodine-3-pyridyl alcohol is useful in many fields.
    In the field of medicine, this compound shows unique potential. or can be used as a key intermediate in the synthesis of many drugs. Due to the particularity of its structure, chemical modification can be used to endow the prepared drugs with unique pharmacological activities. If it is ingeniously modified for specific disease targets, it may be possible to develop new therapeutic drugs, which is expected to bring good news to patients.
    In the field of materials science, 2-iodine-3-pyridyl alcohol can also be used. It can be used to prepare materials with special optical and electrical properties. Its iodine atom interacts with the structure of pyridyl alcohol, which may endow materials with unique photoelectric conversion properties. It may play an important role in the research and development of new materials in optoelectronic devices, such as Light Emitting Diode, solar cells, etc. Furthermore, in the field of organic synthetic chemistry, it is an important building block for organic synthesis and can participate in the construction of many complex organic molecules. Chemists can use it to react with different reagents such as nucleophilic substitution and coupling to synthesize organic compounds with diverse structures, contributing to the development of organic synthetic chemistry and helping to create more organic molecules with novel structures and unique functions.
    To sum up, 2-iodine-3-pyridyl alcohol has important application value in medicine, materials science, organic synthetic chemistry and other fields, and it is a compound that cannot be ignored.