2 Iodo 5 Methoxypyridine

The "5-aminocarbonyl pyridine" mentioned in 2-% E7% A2% 98 has unique and complex chemical properties.
In terms of its physical properties, 5-aminocarbonyl pyridine is usually a crystalline solid and is relatively stable at room temperature and pressure. Its appearance may be white to light yellow powder with a certain melting point, but the specific value varies due to factors such as purity.
In terms of chemical properties, the amino group of 5-aminocarbonyl pyridine (-NH2O) is basic and can react with acids to form corresponding salts. This reaction is based on the electron-acceptable proton of the lone pair of nitrogen atoms in the amino group. For example, when reacted with hydrochloric acid, nitrogen atoms combine hydrogen ions to form salts containing ammonium ions.
Furthermore, its carbonyl (-C = O) part is electrophilic and can participate in a variety of nucleophilic addition reactions. If it is combined with alcohols under the action of appropriate catalysts, a condensation reaction can occur to form the corresponding acetal or semi-acetal structure.
In addition, the pyridine ring of 5-aminocarbonyl pyridine also gives it special chemical activity. The pyridine ring is aromatic and relatively stable, but its electron cloud distribution is uneven, which makes the substitution reaction activity at different positions on the ring different. In the electrophilic substitution reaction, due to the influence of the electronic effect of amino and carbonyl groups, the reaction check point is mainly guided by the two. Amino is the power supply group, which has the activation effect on the adjacent and para-site; carbonyl is the electron-withdrawing group, which has the passivation effect on the meta-site. Under the comprehensive influence, the electrophilic substitution reaction of 5-aminocarbonyl pyridine often occurs at the specific position of the adjacent and para-site of the amino group.
5-aminocarbonyl pyridine has rich and diverse chemical properties. It can be used as a key intermediate in the field of organic synthesis and participates in the construction of many complex organic compounds. It has important application value in many fields such as medicinal chemistry and materials

The common synthesis methods of fudimethylaminopyridine cover the following.
One is the method of using pyridine as the starting material. First, pyridine interacts with dimethyl sulfate to obtain pyridine quaternary ammonium salt. This step requires attention to the reaction conditions, such as temperature, the proportion of reactants, etc., to maintain the yield. Then, the obtained quaternary ammonium salt is reacted with ammonia water or liquid ammonia, and goes through the amination process to obtain dimethylaminopyridine. This approach is slightly complicated, but the raw material is easy to obtain, so it is also commonly used.
The second is the method of using 2-chloropyridine as the starting material. When 2-chloropyridine is reacted with dimethylamine in the presence of an appropriate catalyst and solvent, the choice of catalyst is crucial, which affects the rate and selectivity of the reaction. Bases such as potassium carbonate are usually selected to promote the reaction. This reaction condition is relatively mild, the operation is also convenient, and dimethylaminopyridine can be effectively prepared.
Furthermore, there are also those who use 2-hydroxypyridine as the starting material. First, 2-hydroxypyridine is converted into the corresponding halogenate, and the commonly used halogenating reagents include phosphorus oxychloride. Subsequently, the halogenate is reacted with dimethylamine, and the target product is obtained through a substitution reaction. This process involves halogenation and amination steps, and each step needs to be carefully controlled to achieve good results.
All these synthesis methods have their own advantages and disadvantages. In practical applications, according to the availability of raw materials, cost, reaction conditions and requirements for product purity, the appropriate method is carefully selected to efficiently synthesize dimethylaminopyridine.

2-% E7% A2% 98 - 5-%E7%94%B2%E6%B0%A7%E5%9F%BA%E5%90%A1%E5%95%B6%E5%9C%A8%E4%B8%8D%E5%90%8C%E9%A2%86%E5%9F%9F%E5%A4%9A%E6%9C%89%E5%BA%94%E7%94%A8, detailed as follows:
In the field of medical Dao, this material has extraordinary functions. It can be used as medicine to help the human body reconcile qi and blood. According to ancient medical scriptures, when used in moderation, it can pass the meridians, clear the qi and blood, and has a good effect on various diseases caused by poor qi and blood, such as numbness of the limbs and acute meridians. And it is also beneficial in nourishing the viscera, which can help the viscera restore vitality and gain health.
In the process of alchemy, 2-% E7% A2% 98 - 5-%E7%94%B2%E6%B0%A7%E5%9F%BA%E5%90%A1%E5%95%B6 is also an indispensable material. Alchemists use it as the basis, cooperate with various spiritual objects, and refine them through mysterious fires to obtain magical medicinal pills. This medicinal pill can prolong life, or can enhance physical fitness, or even stimulate the ability of the human body to hide.
In the art of Qimen Hidden Armor, this object also has a unique use. Placed in a specific orientation and layout, it can use its spiritual power to change the aura and reverse the fortune. Or set up a Qimen magic array to resist evil intrusion and ensure one's safety; or use it to adjust the feng shui pattern to make the career of the people living there smooth and the family harmonious.
In the manufacture of organs and equipment, 2-% E7% A2% 98 - 5-%E7%94%B2%E6%B0%A7%E5%9F%BA%E5%90%A1%E5%95%B6 Because of its unique texture, it can make the equipment more sturdy and durable. It can improve the sophistication and stability of the mechanism, making the mechanism operate smoothly and not bad for a long time. For example, the exquisite hidden weapon mechanisms of ancient times and the puppets that operate automatically all rely on this item to improve its quality and efficacy.

There is a market price of diaminoethoxyethanol today, please inquire. This is a commonly used raw material in the field of fine chemicals, widely used in medicine, cosmetics, coatings and other industries. Its price is affected by many factors, such as raw material cost, market supply and demand, production process complexity, etc.
View the cost of raw materials, the preparation of diaminoethoxyethanol requires specific organic compounds as raw materials. If the supply of raw materials is tight, or the production cost rises, such as the price fluctuation of basic raw materials such as petroleum, the cost of diaminoethoxyethanol will increase, and the market price will also fluctuate.
The market supply and demand situation has a deep impact on its price. In the pharmaceutical industry, if there is a sudden increase in demand for new drug research and development, or new products in the cosmetics industry come out one after another, a large amount of this raw material is required, and the supply is not kept up in time, the price will rise; on the contrary, if the market demand is low, the inventory of the production enterprises is overstocked, and the price may be under downward pressure.
Furthermore, the difficulty of the production process also affects the price. If the production process is complex, high-end equipment and exquisite technology are required, and the investment cost is high, the product price will be correspondingly higher; if the process is improved, the cost will be reduced, and the price may be lowered.
Under the heading, the market price of diaminoethoxyethanol varies depending on the quality and purity. Ordinary industrial grade, the price per kilogram is about [X] yuan to [X] yuan; high purity, suitable for medicine or high-end cosmetics, the price per kilogram can reach [X] yuan or more. However, the market is changing rapidly, and the price also rises or falls. To know the exact price, you need to pay attention to the market dynamics in real time and negotiate with relevant suppliers in detail.

2-% title-5-aminoxy pyridine is a white to pale yellow crystalline powder. It has many physical properties and is of great significance to the field of chemical synthesis. It plays a key role in the development of many drugs. The following details its physical properties:
- ** Appearance and Properties **: Under normal circumstances, 2-amino-5-aminoxy pyridine is white to pale yellow crystalline powder, which is convenient for direct identification at the appearance level. The powder has a fine texture. Under the illumination of light, tiny particles can be seen flickering and shimmering, like fine stars scattered in it.
- ** Melting Point and Boiling Point **: The melting point is 144-146 ° C, and the boiling point is about 373.4 ° C. The relatively high melting point indicates that the intermolecular force is strong, and a higher temperature is required to break the lattice structure and realize the transition from solid to liquid; the higher boiling point means that the substance is in the liquid state, and the intermolecular interaction is also strong, requiring a lot of energy to overcome this effect and realize the transition from liquid to gaseous. This characteristic determines that it can exist stably in the solid state at conventional ambient temperatures.
- ** Solubility **: 2-Amino-5-aminoxy pyridine is soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), etc. In DMSO, the substance can be rapidly dissolved to form a uniform, transparent solution, just like ice and snow melted into warm water. However, its solubility in water is poor, only slightly soluble. This is because the molecular structure of the substance, although there are amino groups and other hydrophilic groups, the overall structure is still dominated by hydrophobic pyridine rings, resulting in weak interaction between it and water molecules, making it difficult to dissolve in water in large quantities.
- ** Density and stability **: The density is about 1.34 g/cm ³, and the density is large, indicating that the mass of the substance per unit volume is large. In terms of stability, under conventional storage conditions, the substance is stable in nature and is not prone to spontaneous decomposition or deterioration. However, it should be noted that it is more sensitive to humidity and temperature. When the humidity is too high or the temperature changes drastically, it may affect its chemical stability.
In summary, 2-amino-5-aminoxy pyridine has shown important application value in the field of chemistry and drug synthesis due to its unique physical properties.