As a leading 2-Iodo-Butan supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 2-iodo-butan?
2-Iodo-butan is 2-iobutane, which is a liquid with a special odor. Its chemical properties are active and unique in many chemical reactions.
In nucleophilic substitution reactions, iodine atoms act as a good leaving group, and 2-iobutane often forms a substrate. Taking the reaction with sodium hydroxide aqueous solution as an example, the hydroxyl negative ion nucleophilic attacks, and the iodine ion leaves to generate 2-butanol. This is a typical nucleophilic substitution process. It is determined by single-molecule nucleophilic substitution (SN1) or bimolecular nucleophilic substitution (SN2) mechanism according to the reaction conditions. In case of sodium alcohol, ether products will be formed.
In the elimination reaction, 2-iodobutane is co-heated with potassium hydroxide alcohol solution, and an elimination reaction occurs. The iodine ion and the ortho-site hydrogen atom are removed in the form of hydrogen iodide to form a carbon-carbon double bond, resulting in 1-butene or 2-butene. The proportion of the product depends on the structure of the reactant and the reaction conditions.
Because of its active chemical properties, 2-iodobutane is widely used in the field of organic synthesis and can be used as a key intermediate for constructing complex organic molecular structures. It is an important raw material for organic synthesis chemistry. However, when using it, it is necessary to pay attention to its toxicity and irritation. The operation should be in a well-ventilated environment and follow safety
What are the main uses of 2-iodo-butan?
2-Iodobutane, as well as organic compounds, has a wide range of uses in chemical industry.
First, it is a key intermediate in organic synthesis. It can react with many nucleophilic reagents through nucleophilic substitution reaction to produce a variety of compounds. If combined with alkoxides, it can form ethers. The reason for this reaction is that iodine atoms are highly active and can be easily replaced by nucleophilic reagents to form new carbon-heteroatomic bonds. With this method, ethers with specific structures and functions can be prepared, which are useful in medicine, fragrance and other industries.
Second, in the field of metal-organic chemistry, 2-iodobutane also shows important properties. Interacting with metal magnesium, Grignard reagent can be formed. This Grignard reagent is abnormally active and can react with carbonyl compounds, such as aldides and ketones, to grow carbon chains and synthesize alcohols. This is a common method for growing carbon chains and constructing complex molecular structures in organic synthesis, and has made great contributions to the total synthesis of natural products and drug development.
Third, 2-iodobutane is also involved in materials science. When preparing specific polymer materials, it can be used as an initiator or functional monomer. After polymerization, its structural units are introduced into the polymer chain, giving the material unique properties, such as improving the solubility and thermal stability of the material.
Fourth, in analytical chemistry, it can be used as an internal standard. Due to its specific physical and chemical properties, it can assist in the accurate determination of the content of each component in the sample in gas chromatography, liquid chromatography and other analytical methods, and improve the accuracy and reliability of the analysis.
In short, 2-iodobutane has a place in many fields such as chemical industry, medicine, and materials due to its unique chemical properties, promoting the development and progress of various industries.
What are the synthesis methods of 2-iodo-butan?
There are many different methods for preparing 2-iodine butane, and the following are common ones.
First, n-butanol is used as the starting material. The reaction between n-butanol and hydrogen iodide is quite direct. The hydroxyl group of n-butanol (OH), when encountering the iodine ion (I) in hydrogen iodide, the iodine ion has strong nucleophilicity and attacks the carbon atom connected to the alcohol hydroxyl group. The hydroxyl group leaves in the form of water to obtain 2-iodine butane. During the reaction, it can be heated to promote its speed, but the temperature needs to be controlled moderately to avoid side reactions.
Second, it is prepared from 2-butanol. 2-butanol is co-heated with potassium iodide and sulfuric acid. The function of sulfuric acid is to form hydrogen iodide from potassium iodide, which reacts with 2-butanol. In this process, sulfuric acid also plays a catalytic role. The hydroxyl group of 2-butanol is pre-protonated, which enhances its tendency to leave, and iodine ions then attack to obtain the target product. However, sulfuric acid has strong oxidizing properties, or causes hydrogen iodide to be oxidized, so the concentration and dosage of sulfuric acid must be carefully considered to reduce side reactions.
Third, butene is used as a raw material. Butene and hydrogen iodide undergo an addition reaction. According to the Markov rule, hydrogen atoms of hydrogen iodide are added to double-bonded carbon atoms with more hydrogen, and iodine atoms are added to those with less hydrogen, so 2-iodobutane can be obtained. This reaction condition is relatively mild and the yield is quite good. However, it should be noted that if there is peroxide, the reaction orientation or according to the anti-Markov rule will cause the product to be non-2-iodobutane, so the reaction environment must be strictly controlled.
All methods have advantages and disadvantages. In actual preparation, the choice should be carefully made according to factors such as the availability of raw materials, the difficulty of reaction conditions, the purity and yield of the product.
What are the physical properties of 2-iodo-butan?
2-Iodo-butan is 2-iobutane. This substance has unique properties and several physical characteristics.
Looking at its appearance, 2-iobutane is often a colorless to light yellow transparent liquid, clear and fluid, just like smart water. It may have a faint luster under light, as if it contains a secret brilliance.
Smell its smell, this substance emits a special fragrance, but its taste is not pleasant, but irritating, and the smell is easy to cause nasal discomfort, which is quick to avoid.
In terms of its boiling point, the boiling point of 2-iobutane is quite moderate, about 119 ° C to 120 ° C. At this temperature, the molecules obtain enough energy to break free from each other, and gradually transform from liquid to gaseous state, like a bird that breaks free from the cage and floats in the air.
Its density is greater than that of water, about 1.62g/cm ³. If placed in a container with water, it will sink to the bottom of the water, just like a treasure hidden in the deep sea, lying quietly in a corner.
In terms of solubility, 2-iodobutane is insoluble in water. The two are like water and fire, and the difference in force between molecules makes it difficult to blend. However, it is easily soluble in organic solvents such as ethanol and ether, and can closely embrace and dissolve with organic solvent molecules, showing the characteristics of "similar compatibility".
In addition, 2-iodobutane is volatile. Under normal temperature and pressure, the molecules constantly move out of the liquid surface and gradually disperse in the air, such as curling blue smoke, which is invisible but real.
2-Iodo-butan What to pay attention to when storing and transporting
2-Iodo-butan is 2-iobutane, which is an organohalogenated hydrocarbon. When storing and transporting, many key matters need to be paid attention to to to ensure safety.
Store in the first seal. Because of its volatility, if the seal is not good, it is easy to escape into the air, which not only causes material loss, but also halogenated hydrocarbons are toxic to a certain extent. Volatilization into the air will endanger the environment and human health. Therefore, it should be packed in a container with good sealing performance, such as glass bottles or containers made of specific plastic materials, and ensure that the lid of the container is closed tightly without any gaps.
The second is to avoid heat and store in a cool place. 2-Iodobutane is easy to decompose or cause other chemical reactions when heated. When the temperature is too high, its chemical stability is greatly reduced. Therefore, it should be stored in a low and stable place, away from heat sources, such as heating, fire sources, etc. The warehouse temperature should be controlled within an appropriate range.
Furthermore, it is necessary to avoid light. Halogenated hydrocarbons may cause photochemical reactions and cause them to deteriorate under light conditions. The storage place should be kept dark, or 2-iodobutane should be packaged in opaque packaging materials to prevent direct light.
When transporting, it is also necessary to ensure that the container is stable to prevent collision damage. Because it is a liquid, the container is damaged and easy to flow out, causing environmental pollution and safety hazards. Transportation vehicles need to run smoothly to avoid severe bumps and vibrations. And transportation personnel must be familiar with its characteristics and emergency treatment methods, and can respond quickly and correctly in case of leakage and other accidents.
At the same time, storage and transportation sites should be equipped with corresponding fire and leakage emergency treatment equipment. Such as fire extinguishers, adsorption materials, etc., so that in the event of an emergency, the situation can be controlled in time and the harm can be reduced.