2 Iodoacetophenone
Iodobenzene

2-Iodoacetophenone

Fengxi Chemical

    Specifications

    HS Code

    177658

    Chemical Formula C8H7IO
    Molecular Weight 246.045 g/mol
    Appearance White to off - white solid
    Melting Point 48 - 52 °C
    Boiling Point 262.6 °C at 760 mmHg
    Flash Point 112.6 °C
    Density 1.752 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Odor Characteristic, pungent
    Chemical Formula C8H7IO
    Molar Mass 246.044 g/mol
    Appearance Yellow - brown solid
    Melting Point 37 - 41 °C
    Boiling Point 130 - 132 °C (15 mmHg)
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether, chloroform
    Density 1.829 g/cm³
    Flash Point 113.9 °C
    Stability Stable under normal conditions, but light - sensitive

    As an accredited 2-Iodoacetophenone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of 2 - iodoacetophenone packaged in a sealed, chemical - resistant glass bottle.
    Storage 2 - iodoacetophenone should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, reducing agents, and bases, as it may react with them. Follow proper safety protocols in a dedicated chemical storage facility.
    Shipping 2 - iodoacetophenone is a chemical. Shipping requires proper packaging in line with regulations to prevent breakage and leakage. It must be transported by carriers approved for handling such chemicals, ensuring safety during transit.
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    2-Iodoacetophenone
    General Information
    Historical Development
    2 - Iodoacetophenone is a very important compound in the field of organic synthesis. Looking back in the past, the chemical sages were on the road of organic synthesis, and after countless hard experiments and keen insights, they were able to obtain the synthesis method of this compound.
    In the initial stage, the synthesis method was still immature, and the yield and purity were not satisfactory. However, chemists were not discouraged. With their perseverance and dedication to the pursuit of truth, they continuously improved the experimental conditions and process.
    After years of precipitation, with the improvement of chemical theory and the improvement of experimental technology, the synthesis technology of 2 - Iodoacetophenone has become more and more mature. Its application in medicine, materials and other fields has also become more and more extensive, injecting vigorous impetus into the development of related industries and promoting the progress of human civilization.
    Product Overview
    2 - Iodoacetophenone is an important compound in organic synthesis. Its color is light yellow to brown, like a liquid, with a special odor. The boiling point is about 240 degrees Celsius, and the melting point is between 25 and 29 degrees Celsius.
    This compound is widely used in the field of organic synthesis. It is often used as an intermediate for the preparation of various drugs, dyes and other fine chemicals. In the reaction, the iodine atom is highly active and can participate in many nucleophilic substitution reactions, making it convenient to introduce other functional groups.
    For example, when reacted with alcohols under basic conditions, ether derivatives can be formed; when reacted with amines, nitrogen-containing compounds can be formed. Due to its crucial role in organic synthesis, it has attracted much attention in chemical research and industrial production, which is of great significance for promoting the development of organic synthetic chemistry.
    Physical & Chemical Properties
    2 - Iodoacetophenone, an organic compound. Its physical and chemical properties are quite important to scholars. Looking at its shape, at room temperature, it is solid, colored or nearly white, if crystalline, with a certain melting point, this is one of its physical characteristics. As for chemistry, its iodine atom is active and can be involved in a variety of chemical reactions. Such as the reaction of nucleophilic substitution, iodine is easily replaced by other groups, because its iodine-carbon bond has an appropriate polarity, making the molecule a useful raw material in organic synthesis. And its carbonyl group is also active, and can interact with a variety of nucleophilic reagents to participate in the common reaction of aldones and ketones. Due to its various properties, 2-Iodoacetophenone has a unique position in the field of organic chemistry and is an important substance for chemical research and synthesis.
    Technical Specifications & Labeling
    2 - Iodoacetophenone, the important thing of chemical production. Its manufacturing technology is not easy to produce (commodity production) to the processing. It is easy to follow the grid technology. The quality of raw materials and the quality of the reverse parts cannot be ignored. For example, the degree and strength of the product are slightly worse than the quality of the product.
    To this point, it is clear that the chemical formula C H IO, the molecular weight of the phase is 246.04. The outer layer is often light to brown liquid, with a special taste. Its boiling and melting are also clear, boiling at 265-267 ° C, melting at 19-21 ° C. And it shows its danger, such as irritation, harmful to eyes, skin, etc. In this way, the user can understand its nature, use it, ensure safety, and promote research and work.
    Preparation Method
    To prepare 2-Iodoacetophenone, the raw materials, production process, reaction steps and catalytic mechanism are the key. Acetophenone can be selected as the initial raw material, in an appropriate reaction vessel, with iodine as the halogenating reagent, and under the catalysis of a specific catalyst such as Lewis acid, the electrophilic substitution reaction is initiated.
    First, acetophenone is fully mixed with an appropriate amount of catalyst, the temperature is moderately controlled, and the iodine reagent is slowly added dropwise. Because the carbonyl group of acetophenone changes the electron cloud density of the o-para-position of the benzene ring, iodine ions are easy to attack the ortho-position and form intermediates. This reaction requires precise regulation of temperature and reagent ratio
    After the reaction is completed, the pure 2-Iodoacetophenone is obtained by extraction, distillation and recrystallization. The key to this preparation is to maintain the activity of the catalyst and carefully control the reaction conditions to achieve high yield and high purity.
    Chemical Reactions & Modifications
    2-Iodoacetophenone is also an organic compound. The study of its chemical reaction is quite important to chemists.
    According to the method of the past, the chemical reaction may or may not be good. The yield is not high, and the side effects are proliferating, resulting in the purity of the product, which is not as good as people want.
    Today's scholars have devoted themselves to trying to make the chemical reaction good. New techniques have been developed one after another, and catalysts have been added to increase the speed and selectivity. The method has also been fine-tuned, and the temperature and pressure have been considered. As a result, the yield of 2-Iodoacetophenone has increased significantly, and the side effects have also decreased, and the quality of the product has become more pure.
    This change is a sign of the progress of chemical research. Scholars always take exploration as their business, seek the optimization of chemical application, and contribute to the progress of organic synthesis, hoping to obtain better methods and benefit the world.
    Synonyms & Product Names
    2 - Iodoacetophenone is also a chemical substance. It has the same name, and it is also widely used. In the ancient books, or "2-iodoacetophenone", this is named according to its manufacture. Or those who have its characteristics refer to this thing.
    As for the business name, it also has its own name. Merchants recognize their own characteristics, or take the name of easy. However, what is the name, it refers to 2 - Iodoacetophenone is also. Its use in the field of chemical research, can be used as a raw material for multiple reactions, and a step in the promotion of chemical science. When we study this thing, we can clearly understand its name, so that we can explore the road.
    Safety & Operational Standards
    2-Iodoacetophenone Safety Production and Operation Specifications
    2-Iodoacetophenone is also a commonly used reagent for organic synthesis. In chemical production and experimental operations, its safety and compliance with regulations are related to human life and property, and must not be ignored.
    #1. Storage Rules
    2-Iodoacetophenone should be stored in a cool, dry and well-ventilated place. Keep away from fire and heat sources, and avoid direct sunlight. It should be stored in a sealed container to prevent volatilization and leakage. It must be placed separately from oxidizing agents, acids, alkalis, etc., and must not be mixed to avoid the risk of chemical reactions.
    #2. Operating range
    When operating, wear suitable protective equipment. Wear protective clothing, protective gloves, and safety glasses to prevent it from touching the skin and eyes. It is best to operate in a fume hood to ensure air circulation and disperse volatile gas. During the operation, the movements should be steady and light to avoid violent vibration and impact to prevent damage to the container. If it is necessary to measure, use a precise measuring tool and use it according to the amount required for the experiment. Do not take more waste, and do not take less to cause the experiment to fail to meet expectations.
    #3. Emergency measures
    In case of accidental skin contact, rinse quickly with a large amount of flowing water. The rinsing time should be long, and then seek medical treatment. If it enters the eye, immediately lift the eyelids and rinse thoroughly with a large amount of flowing water or normal saline. It is also necessary to seek medical attention as soon as possible. In the event of a leak, quickly evacuate the personnel from the contaminated area to a safe area and isolate them, strictly restricting access. Emergency responders wear self-contained positive pressure breathing apparatus and anti-virus clothing to cut off the source of the leak as much as possible. Small leaks: Absorb with sand, vermiculite or other inert materials. Large leaks: Build embankments or dig pits for containment, cover with foam to reduce steam disasters, transfer to a tanker or a special collector with an explosion-proof pump, recycle or transport to a waste treatment site for disposal.
    The code of safe production and operation is the foundation of chemical experimentation and production. In the use of 2-Iacetodoophenone, this rule must be observed to ensure safety and orderly experimental production.
    Application Area
    2 - Iodoacetophenone is also a chemical substance. It can be used in the field of synthesis, and can be an important raw material. With its unique chemical properties, it can improve the performance of multiple reactions and help improve the performance of active ingredients.
    In the research of materials, it also has its place. It can improve the properties of materials, such as improving its quality and performance. Because 2 - Iodoacetophenone contains iodine and acetophenone groups, it can be used for special interactions, so it can be used for new properties of materials.
    In addition, in the synthesis of complex materials, it is often used in the synthesis. From different reaction paths, it can be used to synthesize a variety of complex compounds, expand the synthesis path, and promote the development of chemical research.
    Research & Development
    In the field of organic chemistry, I have been researching halogenated aromatic ketones for a long time, and now I focus on 2-Iodoacetophenone. This compound has unique chemical activity. The structure of iodine atoms interacts with the conjugated system of acetophenone, giving it special reactivity.
    To explore its properties, I tried to synthesize it by various methods. After repeated experiments, the reaction conditions were optimized to improve the yield and purity. In the experiment, the effects of reaction temperature, time and the proportion of reactants were carefully investigated.
    Studies have found that 2-Iodoacetophenone can be a key intermediate in many organic synthesis reactions. Through nucleophilic substitution, various functional groups can be introduced to expand the types of its derivatives.
    Looking to the future, we will deeply explore its application potential in the field of medicinal chemistry and materials science. It is hoped that this material can be used to develop new drugs and functional materials, contributing to the development of chemistry.
    Toxicity Research
    I have tried to study the nature of poisons, and recently I have been focusing on 2-Iodoacetophenone. The toxicity of this substance is related to the health of living beings and cannot be ignored.
    After repeated trials, observe its changes in different media, and measure its sympathetic state with other substances. It was found that 2-Iodoacetophenone has a certain toxicity, and its molecular structure makes it easy to interact with molecules in living organisms, or disturb the normal order of cells, and disrupt the metabolic track.
    Although this research is not complete, it has been clear that its toxicity is on the horizon. In the future, we will analyze its toxicology in more detail, and find out the depth of its toxicity under different conditions. It is hoped that it can provide evidence for protection and detoxification methods to avoid its harm to life in the world.
    Future Prospects
    Today there is a thing called 2-Iodoacetophenone. Looking at it, its nature is very different and it has a wide range of uses. In all kinds of chemical things, it can often be seen, either as a raw material or to help the reaction go smoothly.
    We look to the future, this thing will definitely develop its capabilities. The technology of chemical industry is new and new, and 2-Iodoacetophenone will also be explored more. It is expected to open up new paths in the creation of new materials and the production of exquisite pharmaceuticals. Scientific researchers will study its properties and explore its potential with diligence. It is expected that in the future, 2-Iodoacetophenone will shine greatly, and it will make extraordinary contributions to the field of industry and the needs of people's livelihood, adding a splendid color to the development of the future.
    Historical Development
    2 - Iodoacetophenone is also an organic compound. Its historical development can be traced back to the past. At the beginning, the chemists explored the field of organic synthesis and devoted their efforts to the compounds containing iodine aromatic ketones. At that time, the synthesis techniques were not complete, and it was not easy to obtain this 2 - Iodoacetophenone.
    However, with the passage of time, the chemical technology has improved day by day. Scholars have studied many aspects such as reaction conditions and raw material selection. The improved synthesis path has gradually increased its yield and purity. In the past, synthesis may have required complicated steps and harsh conditions, but now it is becoming more simple and efficient. Therefore, the application of 2-Iodoacetophenone in organic synthesis, medicinal chemistry and other fields has become more and more extensive, contributing to the development of chemistry and becoming an indispensable part.
    Product Overview
    2 - Iodoacetophenone is also an organic compound. Its shape is a crystal or liquid with a special odor. This compound has a wide range of uses in the field of organic synthesis and is often a key raw material for the preparation of various complex organic molecules.
    Looking at its structure, there are acetyl and iodine atoms attached to the benzene ring. Due to the electronic effect of iodine atoms and acetyl groups, it has unique chemical activity. In many reactions, iodine atoms can be used as leaving groups, enabling the compound to participate in reactions such as nucleophilic substitution, and then form new carbon-carbon bonds or carbon-heteroatomic bonds. The existence of
    acetyl groups also affects the reactivity and physical properties of molecules. In chemical and pharmaceutical research and development, 2-Iodoacetophenone plays an important role in the synthesis of many compounds with biological activity or special functions due to its special structure and reactivity.
    Physical & Chemical Properties
    2 - Iodoacetophenone is also an organic compound. Its physical properties are solid at room temperature, its color is nearly yellowish, and it has a special odor. The melting point is quite clear, about [specific value] ° C. This characteristic can be relied on when separating and purifying. The boiling point also has a fixed number, about [specific value] ° C., which is related to its gas phase behavior.
    When it comes to chemical properties, the iodine atom in this compound is active and easy to involve nucleophilic substitution reactions. Carbonyl is also an active check point and can interact with many nucleophilic reagents. In case of alkali, it can lead to a series of reactions or cause changes in molecular structure. It is widely used in the field of organic synthesis and can be used as a key intermediate to prepare a variety of complex organic molecules. With their understanding of their physical and chemical properties, chemists can precisely design and manipulate related chemical reactions, contributing to the development of organic synthesis.
    Technical Specifications & Labeling
    For this product, process specifications and identification (product parameters) are the key. The process specifications need to ensure the purity and proportion of raw materials, and the reaction temperature and duration should be precisely controlled. If the material is put, it should be done in sequence and not disordered. React in a special kettle, the temperature is measured by a precise instrument, and it should be controlled in a suitable area, so that it should be stable and efficient.
    In terms of identification, the product name must be clear, accompanied by a chemical formula, indicating its composition. Standard properties, solid and liquid are clear; parameters such as melting point and boiling point are listed, indicating physicochemical properties. Remember the method of harm and protection to warn users. In this way, the process is refined and marked, and the quality of 2-Iodoacetophenone can be guaranteed, and it is also safe to use.
    Preparation Method
    To prepare 2-iodoacetophenone, the raw materials, production process, reaction steps and catalytic mechanism are as follows. First, acetophenone is taken as the raw material, iodine is used as the halogenation reagent, and the halogenation reaction is carried out under the action of a suitable catalyst. The reaction steps are to place acetophenone in the reaction vessel, add an appropriate amount of catalyst, and then slowly drop the iodine solution to control the reaction temperature and stirring rate. The catalytic mechanism is that the catalyst can reduce the activation energy of the reaction, so that the carbonyl ortho-hydrogen of acetophenone is more likely to be replaced by iodine. Through this method, reasonable control of each reaction condition is expected to produce 2-iodoacetophenone efficiently. This process pays attention to the proportion of raw materials, temperature control and reaction time to ensure the purity and yield of the
    Chemical Reactions & Modifications
    Fu 2 - Iodoacetophenone is also an organic compound. In the field of chemistry, its reaction and modification are the top priority for our research.
    Looking at its reaction, it often involves nucleophilic substitution, and the iodine activity of the halogen atom is quite good, which is easy to be replaced by nucleophilic reagents, which can expand its derivation path. Or between redox, depending on the reagents and conditions encountered, the structure and properties of the molecule can be changed.
    As for modification, the introduction of groups can be used to adjust its physical and chemical properties. Such as increasing its lipophilic or hydrophilic properties and changing its reactivity to suit diverse needs. Through exquisite design, 2-Iodoacetophenone is used in the fields of medicine and materials to develop its extraordinary capabilities and contribute to the advancement of chemistry.
    Synonyms & Product Names
    2 - Iodoacetophenone is also a chemical substance. It is the same as the trade name, and the important one is attached to it. In the same category, such as 2-iodoacetophenone, it is also often used. The trade name is different from the family.
    The naming of this object is based on the chemical, 2-Iodoacetophenone is based on its chemical. The same name of 2-iodoacetophenone, also the principle of synthesis, shows that the iodine atom in its molecule is located in the second position of acetophenone.
    As for the trade name, some companies have named it for its characteristics or research. However, the same name or trade name is used to communicate this thing. If a chemical researcher wants to understand this thing, he must understand its characteristics in order to be able to study and use it, communicate it, and operate it precisely.
    Safety & Operational Standards
    2 - Iodoacetophenone Safety and Operating Practices
    2 - Iodoacetophenone is an important chemical substance, which is widely used in many chemical research and industrial production. To ensure its safe use, the operating practices should not be ignored.
    #Storage essentials
    This substance should be stored in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent danger. It should be stored separately from oxidants, acids, and alkalis, etc., and must not be mixed. Because mixed storage can easily cause chemical reactions and endanger safety. The storage area should be equipped with suitable materials to contain leaks, just in case.
    #Operation rules
    Operators must be specially trained and strictly follow the operating procedures. When operating, appropriate protective equipment should be worn, such as a self-priming filter gas mask (half mask), to protect breathing; wear chemical safety glasses to keep your eyes safe; wear anti-poison infiltration work clothes to avoid physical contact; wear rubber oil-resistant gloves to prevent hand contamination. The operation process should be carried out in a fume hood to maintain air circulation and reduce the concentration of harmful gases. Avoid direct contact with skin and eyes. If you come into contact inadvertently, you should immediately rinse with a large amount of flowing water and seek medical treatment in time.
    #Emergency treatment
    If a leak occurs, quickly evacuate the personnel in the leaked contaminated area to a safe area, and isolate them, and strictly restrict access. To cut off the fire source, emergency responders need to wear self-contained positive pressure breathing apparatus and gas clothing. Cut off the source of leakage as much as possible to prevent it from flowing into restricted spaces such as sewers and drainage ditches. In the case of small leaks, it can be adsorbed or absorbed by sand or other non-combustible materials; in the case of large leaks, build a dike or dig a pit to contain it, cover it with foam to reduce the vapor hazard, and then transfer it to a tank car or a special collector for recycling or transportation to a waste treatment site for disposal.
    In short, the safety and operating standards of 2-Iodoacetophenone need to be kept in mind at all times to ensure the safety of personnel and the smooth production.
    Application Area
    2 - Iodoacetophenone, an organic compound. Its application field is quite wide, in the field of medicinal chemistry, it can be used as a key intermediate for the synthesis of many drugs. With its special structure, it can participate in various chemical reactions and help form molecules with specific pharmacological activities.
    In materials science, it also has extraordinary performance. After specific treatment and transformation, it can be integrated into polymer materials to give novel properties to materials, such as improving their optical or electrical properties, making it suitable for the preparation of specific optoelectronic devices.
    In addition, in the field of organic synthetic chemistry, it is often an important building block for the construction of complex organic molecules. With the activity of iodine atoms and carbonyl groups, chemists can skillfully design reaction pathways, expand the structural diversity of compounds, and open up avenues for the creation of new substances.
    Research & Development
    In recent years, I have been in the field of organic synthesis, focusing on the research of 2-Iodoacetophenone. It has great potential and promising prospects in medicine and materials.
    At the beginning, the synthesis method was inconvenient, and the yield was not as satisfactory. Then I dedicated myself to studying, researching ancient books, observing the methods of predecessors, and thinking about ways to improve. After months of trial and error, I finally got an optimized plan. With a specific catalyst, the temperature and pressure of the reaction are regulated, and the yield is unexpectedly doubled, and the purity is also good.
    However, the research path does not end here. To expand its application, explore the road of new drug development. Join hands with medical workers, hoping that it will be helpful in the treatment of diseases. I also think about the creation of materials, hoping to use their characteristics to obtain novel and functional materials.
    I believe that with time and continuous research, 2-Iodoacetophenone will be able to shine in many fields, for the well-being of the world, and for the contribution of scientific research.
    Toxicity Research
    Since modern times, chemical refinement has given rise to various compounds. Today, there is 2-Iodoacetophenone, which is very important for toxicity research.
    As chemical researchers, we have spared no effort to explore the toxicity of 2-Iodoacetophenone. After repeated trials, we have observed its characteristics in different situations. If this substance accidentally touches the skin or enters the body, it may cause various hazards. Its toxicity can disrupt the normal order of the body and damage the function of the viscera.
    Looking at the structure of its molecules and studying the principle of its reaction, we can know the source of toxicity. Although today's protection methods are gradually available, it is still necessary to be cautious about such toxic compounds. In the path of research, we must strictly abide by the procedures to prevent accidental exposure to drugs, protect our own safety, and protect the realm of research from being disturbed by it, paving the way for future generations to explore the mystery of chemistry.
    Future Prospects
    Husband 2 - Iodoacetophenone, an organic compound. In today's chemical research, its characteristics are gradually becoming known. Looking at its structure, the carbon chain is connected to iodine and carbonyl, giving it a unique character.
    Although there is a little progress in basic research at present, there is still a vast field for future expansion. First, in the way of drug creation, it is expected to be a pioneer. After ingenious modification, it may become a cure for diseases and save people from diseases. Second, in the field of materials science, it may be the basis for the synthesis of new materials, shaping materials with specific properties, and using them in electronics and optics.
    We chemical researchers should be enterprising, study its properties, explore its uses widely, and hope to see this compound shine in the future, contributing to human well-being and achieving unprecedented prosperity.
    Where to Buy 2-Iodoacetophenone in China?
    As a trusted 2-Iodoacetophenone manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Iodoacetophenone supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-iodoacetophenone?
    2-Iodoacetophenone is an organic compound. It has unique physical properties, which are listed below:
    Looking at its properties, at room temperature, 2-iodoacetophenone is a colorless to light yellow liquid, with a clear appearance and a special color. Under sunlight or in a bright place, its unique luster can be observed. It smells, there is a special smell, but this smell is not pungent and unbearable, but it has a unique smell. Ordinary people may need to distinguish it carefully.
    When it comes to the melting point, the melting point is about -22 ° C. At this temperature, it changes from solid to liquid, showing the characteristics of material state change. The boiling point is between 262-264 ° C. When the temperature rises, 2-iodoacetophenone of the liquid begins to vaporize and rise into a gaseous state.
    As for the density, its value is about 1.689g/cm ³, which is higher than the common water density. Therefore, if it is mixed with water, it will sink to the bottom of the water. This is a significant feature of its density.
    In terms of solubility, 2-iodoacetophenone is insoluble in water. Due to its molecular structure and weak interaction with water molecules, it is difficult to disperse uniformly in water. However, it has good solubility in organic solvents such as ethanol, ether, chloroform, etc., and can be miscible with these organic solvents in any ratio to form a uniform solution. The physical properties of
    2-iodoacetophenone are determined by its molecular structure and composition, and play a crucial role in many fields such as organic synthesis, laying a solid foundation for its application.
    What is the common synthesis method of 2-iodoacetophenone?
    2-Iodoacetophenone is also an organic compound. The common synthesis methods have the following numbers.
    First, acetophenone is used as the starting material to react with iodine under appropriate conditions. It is often necessary to introduce a catalyst, such as iron powder or its halide. Cover iron and iodine can first react to form iron iodide, which is an active catalyst, which can promote the electrophilic substitution reaction between the aromatic ring of acetophenone and iodine. The carbonyl group of acetophenone is an meta-locator, so iodine tends to replace the 2-position hydrogen atom adjacent to the carbonyl group on the benzene ring. After this reaction, 2-iodoacetophenone can be obtained.
    Second, starting from 2-acetylbenzoic acid. First, 2-acetylbenzoic acid is converted into its acyl chloride form, which can be obtained by interacting with sulfoxide and other reagents. The obtained acyl chloride reacts with nucleophiles such as cuprous iodide to undergo nucleophilic substitution. This process can cleverly introduce iodine atoms at the ortho-position of the acyl group, and then synthesize 2-iodoacetophenone.
    Third, o-iodobenzoic acid and acetyl chloride are used as raw materials. Both are carried out in the presence of appropriate catalysts, such as aluminum trichloride. Aluminum trichloride can react with acetyl chloride to form an active electrophilic reagent, attack the aromatic ring of o-iodobenzoic acid, and introduce acetyl groups at the ortho-position, resulting in 2-iodoacetophenone. This method has its own advantages and disadvantages. In practical application, it is necessary to weigh and choose according to many factors such as the availability of raw materials, the difficulty of reaction, and the purity of the product.
    What are the applications of 2-iodoacetophenone in organic synthesis?
    2-Iodoacetophenone is a widely used compound in organic synthesis. It has many applications in the construction of complex organic molecular structures.
    First, it can be used for nucleophilic substitution reactions. Because of its high activity in the structure of iodine atoms, it is easily replaced by a variety of nucleophilic reagents. If alcohols are used as nucleophilic reagents, iodine atoms can be replaced by alkoxy groups under suitable base catalysis to generate corresponding ether derivatives. This reaction provides an effective path for the synthesis of ether compounds.
    Second, 2-iodoacetophenone also plays an important role in metal catalytic coupling reactions. For example, in the palladium-catalyzed Suzuki coupling reaction, it can be coupled with aryl boronic acid to form new carbon-carbon bonds and construct more complex aromatic compounds. Such reactions are commonly used in the fields of medicinal chemistry and materials science to create new compounds.
    Third, it can be used as a key intermediate for the synthesis of heterocyclic compounds. By reacting with reagents containing heteroatoms such as nitrogen, oxygen, and sulfur, various heterocyclic structures can be formed through a cyclization process. For example, by reacting with o-aminophenol and cyclizing and condensing, benzoxazoles with potential biological activities can be prepared.
    Fourth, in the construction of organic molecules with specific spatial structures, 2-iodoacetophenone can use the localization effect of iodine atoms to guide subsequent reactions to accurately construct the spatial configuration of the target molecule, which is of great significance in the total synthesis of natural products and the molecular design of functional materials.
    From this perspective, 2-iodoacetophenone in the field of organic synthesis, with its unique structure and reactivity, provides rich possibilities for the creation of various organic compounds and promotes the continuous development of organic chemistry.
    What are the storage conditions for 2-iodoacetophenone?
    2 - Iodoacetophenone, there is also a compound. If it is stored, it is necessary to be careful.
    For the first one, this compound is suitable for use in a place where it is dry, dry, and good. In a place where it is dry, it can avoid the harm of high. Because high-quality can promote its transformation, cause changes, or cause danger. In case of hot summer, it is especially necessary to pay attention to the degradation, and do not let it be exposed to the hot sun or high-quality environment.

    It is also necessary to be dry. If this thing encounters moisture, it is vulnerable to deliquescence, or the biochemical reaction of water, breaking its temperature. Therefore, if it is stored, it is appropriate to have a dry place, such as placing a dry place, to absorb the water vapor in the air and keep it dry.
    Furthermore, good health is indispensable. If the storage space is dense, once the material is damaged, the degree of evaporation will increase, which will not affect the material itself, and may cause fire, explosion and other hazards. Good communication, can make the material and escape, and maintain a safe environment.
    In addition, 2-iodoacetophenone should be stored separately. Because of its activity, this material is not connected, and it is easy to react biochemically, which may cause accidents. The storage of 2-iodoacetophenone must be divided and cannot be mixed.
    In order to properly store 2-iodoacetophenone, it is necessary to prevent the connection of incompatible materials, so as to ensure its stability and avoid dangerous life.
    What is the market price of 2-iodoacetophenone?
    I don't know what is going on in the 2-iodoacetophenone city. The fluctuation of the city is affected by various factors, such as the supply and demand, the degree of change in law, the degree of improvement, the fluctuation of the market, etc. If you want to know the price, or you can find the level of chemical transactions, such as the Abba Chemical Industry and the German Chemical Industry, you can test it. Or you can directly explore the supply of chemical products. Or you can test the past transactions and industry reports to get a rough idea of the situation. However, the market is always changing, and it is difficult to cut it. If you want to get the essence, you need to explore it according to the market.