2 Iodoacetophenone

2-Iodoacetophenone is an organic compound. It has unique physical properties, which are listed below:
Looking at its properties, at room temperature, 2-iodoacetophenone is a colorless to light yellow liquid, with a clear appearance and a special color. Under sunlight or in a bright place, its unique luster can be observed. It smells, there is a special smell, but this smell is not pungent and unbearable, but it has a unique smell. Ordinary people may need to distinguish it carefully.
When it comes to the melting point, the melting point is about -22 ° C. At this temperature, it changes from solid to liquid, showing the characteristics of material state change. The boiling point is between 262-264 ° C. When the temperature rises, 2-iodoacetophenone of the liquid begins to vaporize and rise into a gaseous state.
As for the density, its value is about 1.689g/cm ³, which is higher than the common water density. Therefore, if it is mixed with water, it will sink to the bottom of the water. This is a significant feature of its density.
In terms of solubility, 2-iodoacetophenone is insoluble in water. Due to its molecular structure and weak interaction with water molecules, it is difficult to disperse uniformly in water. However, it has good solubility in organic solvents such as ethanol, ether, chloroform, etc., and can be miscible with these organic solvents in any ratio to form a uniform solution. The physical properties of
2-iodoacetophenone are determined by its molecular structure and composition, and play a crucial role in many fields such as organic synthesis, laying a solid foundation for its application.

2-Iodoacetophenone is also an organic compound. The common synthesis methods have the following numbers.
First, acetophenone is used as the starting material to react with iodine under appropriate conditions. It is often necessary to introduce a catalyst, such as iron powder or its halide. Cover iron and iodine can first react to form iron iodide, which is an active catalyst, which can promote the electrophilic substitution reaction between the aromatic ring of acetophenone and iodine. The carbonyl group of acetophenone is an meta-locator, so iodine tends to replace the 2-position hydrogen atom adjacent to the carbonyl group on the benzene ring. After this reaction, 2-iodoacetophenone can be obtained.
Second, starting from 2-acetylbenzoic acid. First, 2-acetylbenzoic acid is converted into its acyl chloride form, which can be obtained by interacting with sulfoxide and other reagents. The obtained acyl chloride reacts with nucleophiles such as cuprous iodide to undergo nucleophilic substitution. This process can cleverly introduce iodine atoms at the ortho-position of the acyl group, and then synthesize 2-iodoacetophenone.
Third, o-iodobenzoic acid and acetyl chloride are used as raw materials. Both are carried out in the presence of appropriate catalysts, such as aluminum trichloride. Aluminum trichloride can react with acetyl chloride to form an active electrophilic reagent, attack the aromatic ring of o-iodobenzoic acid, and introduce acetyl groups at the ortho-position, resulting in 2-iodoacetophenone. This method has its own advantages and disadvantages. In practical application, it is necessary to weigh and choose according to many factors such as the availability of raw materials, the difficulty of reaction, and the purity of the product.

2-Iodoacetophenone is a widely used compound in organic synthesis. It has many applications in the construction of complex organic molecular structures.
First, it can be used for nucleophilic substitution reactions. Because of its high activity in the structure of iodine atoms, it is easily replaced by a variety of nucleophilic reagents. If alcohols are used as nucleophilic reagents, iodine atoms can be replaced by alkoxy groups under suitable base catalysis to generate corresponding ether derivatives. This reaction provides an effective path for the synthesis of ether compounds.
Second, 2-iodoacetophenone also plays an important role in metal catalytic coupling reactions. For example, in the palladium-catalyzed Suzuki coupling reaction, it can be coupled with aryl boronic acid to form new carbon-carbon bonds and construct more complex aromatic compounds. Such reactions are commonly used in the fields of medicinal chemistry and materials science to create new compounds.
Third, it can be used as a key intermediate for the synthesis of heterocyclic compounds. By reacting with reagents containing heteroatoms such as nitrogen, oxygen, and sulfur, various heterocyclic structures can be formed through a cyclization process. For example, by reacting with o-aminophenol and cyclizing and condensing, benzoxazoles with potential biological activities can be prepared.
Fourth, in the construction of organic molecules with specific spatial structures, 2-iodoacetophenone can use the localization effect of iodine atoms to guide subsequent reactions to accurately construct the spatial configuration of the target molecule, which is of great significance in the total synthesis of natural products and the molecular design of functional materials.
From this perspective, 2-iodoacetophenone in the field of organic synthesis, with its unique structure and reactivity, provides rich possibilities for the creation of various organic compounds and promotes the continuous development of organic chemistry.

2 - Iodoacetophenone, there is also a compound. If it is stored, it is necessary to be careful.
For the first one, this compound is suitable for use in a place where it is dry, dry, and good. In a place where it is dry, it can avoid the harm of high. Because high-quality can promote its transformation, cause changes, or cause danger. In case of hot summer, it is especially necessary to pay attention to the degradation, and do not let it be exposed to the hot sun or high-quality environment.

It is also necessary to be dry. If this thing encounters moisture, it is vulnerable to deliquescence, or the biochemical reaction of water, breaking its temperature. Therefore, if it is stored, it is appropriate to have a dry place, such as placing a dry place, to absorb the water vapor in the air and keep it dry.
Furthermore, good health is indispensable. If the storage space is dense, once the material is damaged, the degree of evaporation will increase, which will not affect the material itself, and may cause fire, explosion and other hazards. Good communication, can make the material and escape, and maintain a safe environment.
In addition, 2-iodoacetophenone should be stored separately. Because of its activity, this material is not connected, and it is easy to react biochemically, which may cause accidents. The storage of 2-iodoacetophenone must be divided and cannot be mixed.
In order to properly store 2-iodoacetophenone, it is necessary to prevent the connection of incompatible materials, so as to ensure its stability and avoid dangerous life.

I don't know what is going on in the 2-iodoacetophenone city. The fluctuation of the city is affected by various factors, such as the supply and demand, the degree of change in law, the degree of improvement, the fluctuation of the market, etc. If you want to know the price, or you can find the level of chemical transactions, such as the Abba Chemical Industry and the German Chemical Industry, you can test it. Or you can directly explore the supply of chemical products. Or you can test the past transactions and industry reports to get a rough idea of the situation. However, the market is always changing, and it is difficult to cut it. If you want to get the essence, you need to explore it according to the market.