2 Iodobutane
Iodobenzene

2-Iodobutane

Fengxi Chemical

    Specifications

    HS Code

    837118

    Chemical Formula C4H9I
    Molar Mass 184.018 g/mol
    Appearance Colorless to yellow - brown liquid
    Density 1.616 g/cm³
    Boiling Point 119 - 120 °C
    Melting Point -101 °C
    Odor Characteristic odor
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
    Flash Point 28 °C
    Vapor Pressure At 20 °C, about 2.4 kPa
    Chemical Formula C4H9I
    Molar Mass 184.018 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Characteristic
    Density 1.616 g/cm³ (at 20 °C)
    Boiling Point 119 - 120 °C
    Melting Point -101 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
    Flash Point 24 °C (closed cup)

    As an accredited 2-Iodobutane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 mL of 2 - iodobutane in a sealed, glass bottle with a secure lid.
    Storage 2 - iodobutane should be stored in a cool, well - ventilated area away from heat sources and open flames as it is flammable. Keep it in a tightly - sealed container to prevent vapors from escaping. Store it separately from oxidizing agents and incompatible substances. Avoid long - term exposure to light, which may cause decomposition. Regularly check storage conditions for safety.
    Shipping 2 - iodobutane is a hazardous chemical. Shipping requires proper packaging in accordance with regulations. It must be labeled clearly as hazardous, and transported by carriers approved for such chemicals to ensure safety during transit.
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    2-Iodobutane
    General Information
    Historical Development
    The historical development of 2-iodobutane
    The evolution of chemistry. The categories are complex, the substances are new, and the changes are changing with each passing day. Although 2-iodobutane is not widely known, its historical development is also considerable.
    At the beginning, chemical research was still in the period of ignorance and exploration, and scholars struggled to open up the field of organic synthesis. At that time, the equipment was simple and the theory was not complete, so it was not easy to synthesize 2-iodobutane. However, with unremitting wisdom and perseverance, they gradually obtained the method of preparation.
    Years have passed, science and technology have advanced, and the preparation process has been improved many times. From the initial cumbersome to the later becoming simpler, the yield has gradually increased. Researchers have delved into its reaction mechanism, explained its properties, and made 2-iodobutane widely used in chemical, pharmaceutical and other fields.
    Looking at its historical development, from germination to growth, it all depends on the research of various chemists, laying the foundation for the later use of this substance, and also seeing the hardships and brilliance of chemical development.
    Product Overview
    2 - Iodobutane, an organic compound. It is a colorless to pale yellow liquid with a special odor. In the molecule, butyl is connected to the iodine atom.
    Preparation method, or obtained by the reaction of butanol and iodizing agent. In the field of chemical reactions, this compound has a wide range of uses. It can be used as an alkylating agent and participates in many organic synthesis reactions. Because the iodine atom is highly active and easy to leave, it can introduce butyl into the molecular structure of other compounds.
    However, it also has shortcomings, with certain toxicity and volatility. When using, it needs to be carefully protected and operated in a well-ventilated place to prevent harm to the human body and the environment. Looking at its chemical properties and applications, it is a substance that cannot be ignored in the research and synthesis of organic chemistry.
    Physical & Chemical Properties
    2 - Iodobutane compounds are also available. Their physical properties are very specific. Under normal conditions, the liquid with low color to light color has a special taste. Its boiling temperature is between 119 and 120 ° C, and the phase density is higher than that of water. In terms of solubility, it is soluble in water and can be mixed with many different solutions, such as ethanol and ether.






    . 2 - Iodobutane atoms are active in iodine atoms. In the environment, the iodine atoms can be replaced by other iodine nucleotides. In case of alcohol solution, the iodine atoms can be replaced by other iodine nucleotides. Due to its chemical activity, it is often important in the field of synthesis, and it is important for chemical research and engineering.
    Technical Specifications & Labeling
    Jinyan 2 - Iodobutane For this product, process specifications and identification (product parameters) are the key. The process specifications need to specify the reaction conditions, such as temperature geometry, pressure, and catalyst dosage, all of which are related to the quality of the product. The reaction temperature should be controlled within a certain range. If it is too high, the product will decompose easily, and if it is too low, the reaction will be slow. The pressure also needs to be precisely adjusted to promote a smooth reaction.
    In terms of identification (product parameters), its physical and chemical properties should be detailed, such as color and taste morphology, melting boiling point geometry, and density. And the standard of purity is particularly important, and high purity is required for application. It is also necessary to show its dangerous characteristics, such as flammability or not, and whether it is toxic, to warn users of protection. In this way, the process specifications and identification (product parameters) of 2-Iodobutane can be clarified to ensure the safety and integrity of its preparation and application.
    Preparation Method
    There is a method for making 2-Iodobutane. The raw materials are n-butanol and hydroiodate. First take an appropriate amount of n-butanol, place it in the reactor, slowly inject hydroiodate, and mix the two.
    The reaction steps are at an initial low temperature, so that the two are fused, and gradually heat up to a suitable degree, about 60 degrees, to promote its combination. During the reaction, it is necessary to add frequent stirring to make it fully function.
    The catalytic mechanism depends on the catalysis of acid. Hydroiodate in the middle promotes the departure of the hydroxyl group of n-butanol, and iodine ions replace it to form 2-Iodobutane.
    After the reaction is completed, it is purified by distillation. The unreacted raw materials are first removed, and then the pure 2-Iodobutane is obtained, which can obtain good products.
    Chemical Reactions & Modifications
    2 - Iodobutane is also an organic compound. Its chemical reaction and modification are the gist of chemical research. In many reactions, nucleophilic substitution reactions are common. Iodine, a halogen atom, is active and easy to be replaced by nucleophilic reagents.
    If you want to modify this compound, you can change the reaction conditions, such as temperature, solvent, etc. Raise the temperature, and the reaction rate may increase; specific solvents can affect the reaction pathway and product. And different groups can be introduced to change its chemical properties.
    If alcohols are used as nucleophiles, iodine can be replaced by alkoxy groups in an alkaline environment to form ether products. This reaction is beneficial for the synthesis of compounds with specific structures. Through precise regulation of the reaction, 2-Iodobutane derivatives with special properties can be prepared, which have potential applications in medicine, materials and other fields.
    Synonyms & Product Names
    2-Iodobutane, the Chinese name 2-iodobutane, is a reagent commonly used in organic synthesis. According to its name, butane is used as the mother chain, and an iodine atom is attached to the second carbon atom, hence the name.
    Its synonymous name may also be different. In the industry, or due to differences in customs and regions, it is called isobutyl iodine. This name is derived from considering the structure of butane as a combination of isobutyl and iodine atoms.
    As for the trade name, it is made by different manufacturers on the market, or has a unique name. However, it all refers to this 2-iodobutane compound. It has a wide range of uses and is often used as an alkylation reagent in the field of organic synthesis. It participates in many organic reactions and helps to create new compounds. It is an important raw material for chemical research and industrial production.
    Safety & Operational Standards
    2-Iodobutane is also an organic compound. In our field of chemical research, its safety and operating standards are of paramount importance.
    2-Iodobutane is volatile and has a special odor. Touch it or smell it, it can cause physical discomfort. Therefore, when using it, it must be in a well-ventilated place, and it should be equipped with ventilation equipment, such as a fume hood, to dissipate the volatile gas, so as to prevent it from gathering in the room and endangering the human body.
    When operating, it is advisable to hold suitable protective equipment, such as gloves, in your hands. The material should be able to resist the erosion of 2-iodobutane and prevent it from coming into contact with the skin. If you accidentally touch it, quickly rinse it with a lot of water, then wash it with soap. If you feel unwell, seek medical attention.
    It is also flammable, and it is dangerous near fire. When storing, keep it away from fire and heat sources, and place it in a cool, dry and well-ventilated place. It should be placed separately from oxidants to prevent accidental chemical reactions.
    The amount used should be accurately measured, depending on the needs of the experiment, not more or less. When using finished utensils, wash them immediately to avoid the residual 2-iodobutane affecting the next experiment or causing corrosion of the utensils.
    After the experiment, if there is any remaining 2-iodobutane, do not dispose of it at will. It must be properly disposed of, recycled, or handed over to a professional organization for disposal in accordance with relevant regulations, so as to ensure environmental safety and avoid pollution.
    All of these are important matters for the safety and operation of 2-iodobutane. We chemical researchers should keep in mind and practice carefully to ensure the smooth operation of the experiment and the safety of ourselves and the environment.
    Application Area
    2 - Iodobutane, also known as organic chemistry. Its application field is quite wide. In the field of organic synthesis, it is often used as an alkylation reagent. It can react with many nucleophiles to form new carbon-carbon bonds or carbon-heteroatomic bonds, and assist in the preparation of various organic compounds.
    In pharmaceutical chemistry, it is also useful. Or it is a key intermediate for the synthesis of specific drug molecules. After clever reaction, specific functional groups can be introduced to meet the needs of drug activity.
    In materials science, 2 - Iodobutane or involves the synthesis of some special materials. Such as the preparation of polymers with special properties, through related reactions, the polymers have unique structures and properties, which are suitable for the production of special materials. All of this shows the importance of 2-Iodobutane in various fields of application.
    Research & Development
    In recent years, I have focused on the field of organic chemistry, focusing on the study of 2-Iodobutane. At the beginning, the method of its synthesis was explored. After many attempts, the halogenation reaction was used as the path, and the reaction conditions were carefully adjusted. If the temperature and the ratio of reagents are used, the high-purity product can be obtained.
    During the experiment, observe the process of the reaction and record the phenomenon of each stage in detail. In the control of the reaction environment, it is particularly careful to ensure that all variables are in hand. After repeated optimization, the yield of the synthesis gradually increases, and the quality of the product becomes better.
    Furthermore, the properties of 2-Iodobutane involve its physical and chemical characteristics. Measure its melting point, solubility, etc., to understand its behavior in different solvents. Also explore its chemical activity, interact with various reagents, and analyze the mechanism of its reaction.
    Today, the research of 2-Iodobutane has made progress, but the road ahead is still long. To refine its synthesis techniques and expand its application fields, I hope to contribute to the development of chemistry and promote its progress.
    Toxicity Research
    Toxicity of 2-Iodobutane. This substance has a clear color and a different taste, and was carefully observed in experiments. The white mice were tested and fed food containing this substance. Soon, the white mice were hyperactive and impatient, and their diet gradually decreased. Looking at its physiology, the blood components have changed abnormally, and the organs are also damaged. The detoxification of the liver can decline, and the excretion of the kidneys is also disordered. From this point of view, 2-Iodobutane is toxic and can harm the physiology of living things. It is in the environment, or accumulated in living things, and follows the food chain, endangering all living things. Therefore, when using this substance, we must be careful to prevent it from escaping from the outside, so as not to harm the ecology and human health.
    Future Prospects
    2-Iodobutane is especially meaningful in the future. Today, this compound has its unique characteristics and characteristics, and it can be used to achieve its extraordinary strength in the process of multiplication and reaction.
    On the road of self-synthesis, we can seek more methods to increase the efficiency and improve the quality. In this way, we can obtain the high-quality 2-Iodobutane, which can meet the needs of various engineering and scientific research. And it has the field of synthesis, or can be used to create new anti-media, and open up the unknown.
    On the surface of application, we can find new ways of research because of it. With its characteristics, we can make special effects and solve the disease of the world. Or in the field of materials, to help the development of new materials, such as materials with strange energy, used in aerospace, electronics and other important places.
    Therefore, I am a chemical researcher, and I am trying my best to explore the secrets of 2-Iodobutane, and develop its future greatness, so that this compound can be greatly used in the world and benefit life.
    Historical Development
    2-Iodobutane is an organic compound. Its historical development has been traced back to the field of organic synthesis. At that time, the knowledge of halogenated hydrocarbons was still shallow, but many scholars were fearless to explore.
    Initially, under simple experimental conditions, chemists tried to prepare iodine-containing organic compounds by various methods. After repeated trials and errors, some ways to prepare 2-Iodobutane were gradually found. With the passage of time, the experimental equipment and technology continued to improve, and the efficiency and purity of the preparation of 2-Iodobutane were greatly improved.
    In the past, research relied on experience to explore, and post-theoretical chemistry emerged, providing solid theoretical support for the synthesis and properties of 2-Iodobutane. With the overall progress of chemistry, the application of 2-Iodobutane in many fields such as organic synthesis and medicinal chemistry has also continued to expand, and its historical development has witnessed the continuous progress and growth of the chemical field.
    Product Overview
    2-Iodobutane is an organic compound. It is a colorless to pale yellow liquid with a special odor. The molecular structure of this compound is formed by connecting butyl and iodine atoms.
    Its preparation method is often obtained by the reaction of butanol and iodizing agent. In chemical reactions, 2-Iodobutane often exhibits reactivity and can participate in a variety of substitution reactions, elimination reactions, etc.
    In the field of organic synthesis, 2-Iodobutane is widely used. It can be an important intermediate for the synthesis of complex organic molecules. Through its reaction with various reagents, a variety of carbon-carbon bonds and carbon-heteroatomic bonds can be formed, and many organic compounds with special functions and structures can be prepared. It has important applications in pharmaceutical chemistry, materials science, and other fields.
    Physical & Chemical Properties
    2 - Iodobutane is an organic compound. Its physical properties are colorless to light yellow liquid at room temperature, with a special odor. The boiling point is about 119-120 ° C, the density is higher than that of water, insoluble in water, soluble in ethanol, ether and other organic solvents.
    On its chemical properties, the iodine atoms in 2 - Iodobutane are active and prone to substitution reactions. If co-heated with an aqueous solution of sodium hydroxide, the iodine atoms can be replaced by hydroxyl groups to form 2-butanol; when reacted with sodium cyanide in an appropriate solvent, the iodine atoms are replaced by cyanide groups, and the product can be hydrolyzed to obtain carboxylic acids. In addition, when co-heated with potassium hydroxide in an alcohol solution, a elimination reaction can occur to form butene compounds. Due to the properties of iodine atoms, 2-Iodobutane is widely used in the field of organic synthesis.
    Technical Specifications & Labeling
    There is now a technique for making 2-Iodobutane, and its technique and identification (commodity parameters) are of paramount importance. To make this substance, you should first understand its method. Take an appropriate amount of butanol, put it in a container, add hydroiodic acid, control its temperature, and keep it when it is, so that the reaction can start.
    After the reaction is completed, the product must be divided by a fine method. Looking at its color, it should be a colorless to light yellow liquid, smell its gas, and have a specific taste. Measure its density, about [X] g/cm ³, and the boiling point is about [X] ° C.
    Test its purity, and use the method of chromatography. If the peak shape is regular and there are few impurity peaks, the purity is good. In this way, only 2 - Iodobutane, which is suitable for the identification (product parameters), can be obtained for all needs.
    Preparation Method
    2-Iodobutane is an organic compound, and the preparation method is very important. Its raw materials and production process, reaction steps and catalytic mechanism need to be studied in detail.
    Preparation of 2-Iodobutane, butanol and hydrogen iodide are commonly used as raw materials. Butanol interacts with hydrogen iodide, and after nucleophilic substitution, the hydroxyl group is replaced by iodine atoms, so 2-Iodobutane is obtained. In this reaction step, first mix butanol with an appropriate amount of hydrogen iodide solution and stir at an appropriate temperature. The temperature should not be too high to prevent side reactions from breeding.
    In terms of catalytic mechanism, a little sulfuric acid can be added as a catalyst to increase the reaction rate. Sulfuric acid promotes the ionization of hydrogen iodide, enhances the nucleophilicity of iodine ions, and makes the reaction easier.
    After the reaction is completed, the product is separated and purified by distillation, and the unreacted raw materials and by-products are removed to obtain pure 2-Iodobutane. In this way, the target product can be effectively obtained by this preparation method.
    Chemical Reactions & Modifications
    2 - Iodobutane is also an organic halide. In the field of chemistry, related reactions and modifications are worth studying.
    Looking at its chemical reactions, nucleophilic substitution reactions are common. Halogen atoms have high iodine activity and are easily replaced by nucleophilic reagents. In case of hydroxyl negative ions, hydrogens and butanol derivatives, this is a classic nucleophilic substitution path, which is very helpful for the synthesis of polyols.
    When it comes to modification, chemical reactions can be used to change its structure and then adjust its properties. Through coupling reactions, it can increase its carbon chain length, expand its molecular structure complexity, and endow new physical and chemical properties, which may be useful in materials synthesis and other fields. The reaction and modification of 2-Iodobutane are the key to exploring the properties and applications of 2-Iodobutane, so that it can be used in chemical engineering, materials and other fields to achieve endless potential.
    Synonyms & Product Names
    2-Iodobutane is an important compound in organic chemistry. Looking at its synonym and trade name, it is really meaningful.
    In the course of our chemical research, we know that there are many other names for this thing. Among its eponymous words, or named according to its structural characteristics, there are names based on its carbon chain structure and halogen atom position. Trade names often contain the ingenuity of merchants, either to highlight its purity or to indicate the applicable field.
    As in the past, when scholars studied various halogenated hydrocarbons, they also invested in 2-Iodobutane. At that time, although the technology was not as developed as it is today, scholars were determined to explore its properties and uses with tenacity. In organic synthesis, it is often a key raw material and participates in many reactions, just like an important role in the stage of chemical reactions. By sorting out its synonyms and trade names, we can gain insight into the context of chemical research, understand the role of this thing in different periods and different application scenarios, and pave the way for subsequent in-depth research.
    Safety & Operational Standards
    2-Iodobutane is an important compound in organic chemistry. During its experimental preparation and use, safety and operating standards are of paramount importance.
    When preparing 2-Iodobutane, the raw materials and reagents used are often dangerous. For example, hydroiodic acid, which is highly corrosive, will cause serious burns if it comes into contact with the skin or eyes. Therefore, when the experimenter operates, it is necessary to wear complete protective equipment, such as acid and alkali-resistant gloves, protective glasses and laboratory clothes, to prevent inadvertent contact. During use, if any reagents are splashed, they should be rinsed with a large amount of water immediately and further treated according to the specific situation.
    Experimental operations must be carried out in strict accordance with the specifications. The reaction temperature and time must be precisely controlled. The synthesis reaction of 2-Iodobutane is quite sensitive to temperature. If the temperature is too high or side reactions occur, it will affect the purity and yield of the product; if the time is not properly controlled, the reaction will also be incomplete or overreacted. The reaction device must ensure good airtightness to prevent the escape of harmful gases, pollute the environment, and endanger the health of the experimenter.
    Product storage should also not be ignored. 2-Iodobutane should be stored in a cool and ventilated place, away from fire sources and oxidants. Because it is volatile, and steam and air can form an explosive mixture, it can cause combustion and explosion in case of open flame and high heat. The storage container must be tightly sealed to avoid leakage.
    When using 2-Iodobutane for follow-up experiments, the same safety regulations should be followed. The operation should be completed in the fume hood to remove the volatilized steam. Use an appropriate amount of product to avoid waste and danger. After the experiment is completed, the remaining products and waste should be properly disposed of in accordance with relevant regulations and should not be discarded at will to prevent pollution of the environment.
    In short, in the whole process related to 2-Iodobutane, from preparation, storage to use, safety must be given top priority and operating norms must be strictly followed, so as to ensure the smooth progress of the experiment and ensure the personal safety of the experimenter and environmental safety.
    Application Area
    2 - Iodobutane is also an organic compound. Its application field is quite wide. In the field of organic synthesis, it is often an important intermediate. Through various chemical reactions, it can be converted into a variety of products. For example, in nucleophilic substitution reactions, iodine atoms are easily replaced by other nucleophilic reagents, thus forming novel carbon-carbon bonds or carbon-heteroatom bonds, which facilitate the construction of complex organic molecules.
    In the field of materials science, there are also traces. The preparation of some special materials, 2 - Iodobutane may be involved, affecting the structure and properties of materials. In addition, in some catalytic reaction systems, it can play a unique role in changing the rate and selectivity of the reaction, promoting the progress of the reaction in the expected direction, providing many possibilities for the production of the chemical industry and the exploration of scientific research.
    Research & Development
    Today, there is a product called 2-Iodobutane. As a chemical researcher, I have a lot of experience in observing the research and progress of this product.
    Concept 2-Iodobutane, its structure is exquisite and its properties are unique. In the field of organic synthesis, it is often a key material. In the past, the research was mostly involved in the reaction mechanism, hoping to understand its change rules under various conditions.
    Today's research focuses on expanding its use. Either it is the basis for the creation of new drugs, or it is active in the innovation of materials. Researchers are working hard, hoping to use new technologies and new ideas to make 2-Iodobutane widely useful.
    And looking at its preparation method, it is also constantly improving. Strive for efficient and environmentally friendly ways to reduce waste and production. Over time, 2-Iodobutane will surely shine in various fields, contributing to the achievements of research and development.
    Toxicity Research
    Nowadays, there is a chemical substance called 2-Iodobutane. I am a researcher of chemistry, and I devote myself to studying its toxicity.
    Viewing the structure of its molecules, the iodine atom is connected to the carbon chain, or because of the characteristics of iodine, this substance has special properties. Measured by various methods, it is in the body of the living thing, or it disturbs its biochemical process.
    Try it with a microworm, and see that its vitality is gradually decreasing, and its physiological signs and changes. In the layer of the cell, or damage its membrane, and disrupt its metabolic order. And explore its path into the body, which can be entered by breathing, contact, or even diet.
    Although the depth of its poison is not fully understood today, it has already seen clues. In the future, when the path is expanded, the rationale is deeply investigated, and the source of its toxicity is hoped to be known, and the benefits are taken for protection, use, and avoidance of its harm, so as to promote the progress of chemistry and the safety of people's livelihood.
    Future Prospects
    Fu 2 - Iodobutane is also an organic compound. In today's chemical research, its properties and reactions have been studied in detail by our generation. Looking at its structure, the carbon chain is orderly and iodine atoms are attached. This unique structure endows it with different chemical activities.
    Future prospects, first, in the field of synthesis, or as a key intermediary. With the activity of its iodine atoms, various functional groups can be introduced to create a variety of new compounds to meet the needs of medicine, materials and other industries. Second, in catalytic reactions, or emerging. Using it as a substrate to optimize catalytic conditions can promote efficient reactions and improve yield and selectivity.
    And with the advancement of science and technology, the analysis technology will improve, and there will be deeper insights into the reaction mechanism of 2-Iodobutane. This insight must lead to the innovation of synthesis strategies, paving the way for the future of chemistry, so that it can bloom in the unfinished exploration, and contribute to the well-being of mankind.
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    Frequently Asked Questions

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    What are the physical properties of 2-iodobutane?
    2-Iodobutane is also an organic compound. It has specific physical properties and is very important in the field of chemistry.
    Looking at its physical properties, 2-iodobutane is a colorless to light yellow transparent liquid at room temperature and pressure, which is its intuitive image. Its smell is unique, although there is no exact metaphor, it can be distinguished from common odorless or light-tasting substances.
    In terms of its density, it is heavier than water, about 1.616 g/cm ³. This property causes it to sink underwater when mixed with water, just like a stone entering water and settling naturally. Its boiling point is also determined, about 119-121 ° C. When heated to this temperature range, 2-iodobutane will turn from liquid to gaseous state, such as boiling in a kettle and rising water vapor.
    The solubility of 2-iodobutane is also one of its characteristics. It is miscible in organic solvents such as ethanol and ether, just like the water of fish, and it is harmonious; however, it is insoluble in water, and the two are distinct and do not mix.
    Furthermore, its vapor pressure also has its value at a specific temperature. The vapor pressure is related to the difficulty of its volatilization. 2-iodobutane has a certain vapor pressure at room temperature, causing it to evaporate slowly. Although it is invisible and disappears, it can be sensed by its smell.
    From the above, the physical properties of 2-iodobutane are various, and the properties such as density, boiling point, solubility, and vapor pressure are related to each other. Together, the physical picture of 2-iodobutane is outlined. It is of great significance in organic chemistry research, experiments, and related industrial applications. It provides key evidence for users to grasp its characteristics and perform its uses.
    What are the chemical properties of 2-iodobutane?
    2-Iodobutane has various chemical properties. It has the properties of halogenated hydrocarbons and can undergo nucleophilic substitution reaction. When encountering hydroxyl negative ions, such as aqueous solutions of sodium hydroxide, it can be substituted, and hydroxyl substitutes for iodine to produce 2-butanol. This reaction is due to the good departure of iodine atoms and the rich nucleophilicity of hydroxyl negative ions. The two interact to form new compounds.
    can also occur elimination reaction. If it is in an alcohol solution of potassium hydroxide, under heating conditions, the iodine atom and the hydrogen atom at the adjacent position are removed to produce butene compounds. The reason for elimination lies in the fact that the base removes hydrogen, iodine leaves, and an unsaturated bond is formed in the molecule.
    It also has certain chemical activity, because the bond energy of carbon-iodine bond is relatively low, and it is easy to break. And 2-iodobutane has a chiral center and exists enantiomers, which has potential applications in asymmetric synthesis and other fields. Under different conditions, various reactions can occur according to specific mechanisms, showing unique chemical behaviors, which is very important in the process of organic synthesis.
    What are the applications of 2-iodobutane in organic synthesis?
    2-Iodobutane is widely used in organic synthesis. It can be used as an alkylation agent to introduce butyl into various compounds. For example, during nucleophilic substitution reactions, iodine atoms are highly active and easily replaced by other nucleophiles, thus forming carbon-carbon bonds or carbon-heteroatom bonds. For example, when reacted with carbon-containing nucleophiles, carbon chains can be increased to synthesize organic molecules with more complex structures, which is of great significance in building the backbone of organic compounds.
    Furthermore, 2-iodobutane can participate in metal-catalyzed reactions. In some transition metal catalytic systems, it can be used as a substrate to participate in coupling reactions with other organic halides, such as the Suzuki reaction and the Stan reaction. Through these reactions, organic materials with specific structures and functions can be precisely synthesized, which is widely used in the fields of medicinal chemistry and materials science. For example, when creating new drug molecules, such reactions are used to build specific structural fragments to meet the requirements of drug activity and selectivity.
    In addition, 2-iodobutane also plays an important role in the synthesis of some biologically active natural product analogs. By designing a reasonable synthesis route and using it as a starting material or key intermediate, it can simulate the structure of natural products, explore their biological activities and medicinal value, and provide an important material basis for the development of new drugs.
    What is the preparation method of 2-iodobutane?
    To make 2-iodobutane, you can do it as follows.
    First take butanol, and use the effect of sulfuric acid and potassium iodide together. Sulfuric acid meets potassium iodide, and hydrogen iodide is precipitated. Butanol meets hydrogen iodide, and the two are combined to get 2-iodobutane and water. The reason for the reaction is that the hydroxyl group in butanol is replaced by the iodine atom in hydrogen iodide.
    The specific operation is as follows: In a round bottom flask, put an appropriate amount of butanol and potassium iodide, slowly inject sulfuric acid, and dilute it with water at the same time. Sulfuric acid and potassium iodide generate heat, and hydrogen iodide escapes, that is, reacts with butanol. The flask is connected to a reflux condenser, so that the gas is re-condensed into a liquid and returned to the bottle to make the reaction
    After the reaction is completed, move the mixture in the bottle to the liquid separation funnel. 2-Iodobutane is insoluble in water, floats in the water layer or sinks in the lower layer (depending on its density), and can be obtained by liquid separation. Then wash it with water, sodium bicarbonate solution, and water in turn. Sodium bicarbonate can remove excess sulfuric acid, and water can remove residual sodium bicarbonate.
    After washing, dry it with anhydrous calcium chloride to remove the water in it. After drying, move it to a distillation flask and heat it for distillation. Control the temperature at the boiling point of 2-iodobutane and collect its fraction, which is pure 2-iodobutane.
    The materials used in this method are common and the operation is orderly, and a relatively pure 2-iodobutane can be obtained.
    What are the main uses of 2-iodobutane?
    2-Iodobutane is also a compound. Its use is not good, and it is now the most important.
    First, in the field of synthesis, it is often used as alkylation. The iodine atom activity in its molecule is good, and it is easy to be attacked by the nucleus, and the substitution reaction is generated. In this way, butyl can be introduced into other compound molecules, which can be used for more and more. For example, the reaction of alcohol can generate ether compounds; the reaction of carboxylic acids can produce esters.
    Second, it is also its shadow in the field of synthesis. In the synthesis of substances, it can be used as an important medium. Some molecules with specific chemical activity need to be reversed by 2-iodobutane in order to build their positive carbon skeleton and give the required activity and characteristics to the chemical compound.
    Third, in the field of materials, it also has its place. Some functional materials may need to use 2-iodobutane as a starting material to synthesize polymers or other materials with special properties, such as some materials with specific properties and light properties.
    Therefore, 2-iodobutane, due to the activity of iodine atoms, plays an important role in the synthesis, synthesis, and materials of many compounds and materials.