2 Iododibenzofuran

2-Iododibenzofuran, or 2-iodibenzofuran, is widely used.
It plays an important role in the field of organic synthesis. It can be used as a key intermediate to derive complex and unique organic compounds through various chemical reactions. For example, it can carry out nucleophilic substitution reactions with nucleophiles to form new carbon-heteroatom bonds, thus paving the way for the synthesis of compounds with special biological activities or material properties. With the activity of iodine atoms, it can be cleverly connected with other organic fragments through metal-catalyzed coupling reactions, such as Suzuki reaction, Stille reaction, etc., providing the possibility for the synthesis of complex polycyclic aromatic hydrocarbons. Such compounds have great potential application value in the fields of medicine and materials.
In the field of materials science, 2-iododibenzofuran also shows unique charm. Due to the special optoelectronic properties endowed by its molecular structure, it can be prepared into organic semiconductor materials after rational chemical modification and processing. Such materials are expected to exhibit excellent charge transfer and luminescence properties in devices such as organic Light Emitting Diode (OLED) and organic field effect transistor (OFET), which will contribute to the development of new high-performance optoelectronic devices.
In terms of medicinal chemistry, its potential value should not be underestimated. As compounds with specific structures, based on 2-iododibenzofuran, through structural modification and optimization, it is expected to develop lead compounds with unique biological activities. These lead compounds may become innovative drugs for treating specific diseases and contribute to the cause of human health after in-depth pharmacological research and development.

2-Iododibenzofuran is an organic compound with unique physical properties. Its shape is mostly crystalline solid, stable at room temperature and pressure. Looking at its appearance, it is often in the state of white to light yellow crystalline powder, fine and homogeneous.
When it comes to the melting point, it is about a specific temperature range. This property is of great significance for the identification and purity determination of compounds. Melting point determination can help to distinguish its purity. The melting point range of pure products is narrow, and the melting point of impurities is reduced and the melting range is widened.
2-Iododibenzofuran is insoluble in water, because water is a polar solvent, and the compound has a non-polar structure. According to the principle of "similar miscibility", the two have poor miscibility. However, it is soluble in a variety of organic solvents, such as dichloromethane, chloroform, toluene, etc. In organic solvents, it can be better dispersed and dissolved, providing convenience for organic synthesis and related experiments.
Its density is also an important physical property. Although the specific value varies depending on the measurement conditions, it has a relatively fixed value under specific conditions. Density is related to the distribution and separation of compounds in mixtures, and is indispensable for chemical production and experimental operation planning.
In addition, 2-iododibenzofuran has a certain vapor pressure. Although the vapor pressure is low at room temperature, the temperature rises, the vapor pressure increases, and some of it will evaporate to the gas phase. This property needs attention during storage and use to prevent its volatilization loss or cause safety problems.
Overall, the physical properties of 2-iododibenzofuran determine its application in organic synthesis, materials science, and other fields. Understanding these properties allows for better manipulation and application of this compound.

2-Iododibenzofuran is an organic compound. Its molecular structure contains the skeleton of dibenzofuran, and is connected to the iodine atom at the second position. Such compounds have specific chemical properties.
In terms of reactivity, the iodine atom has high electronegativity and polarizability, so that the two positions of the molecule become the reactive activity check point. In the case of nucleophiles, iodine atoms are easily replaced. In the nucleophilic substitution reaction, nucleophiles such as hydroxyl anions and amino anions can attack the second position of 2-iododibenzofuran, and the iodine ions leave to form new derivatives. This process requires suitable solvents and reaction conditions to promote the activity of nucleophiles and the solubility of substrates.
And because of its conjugated aromatic system, it also has characteristics in the field of photochemical reactions. Under light, electrons can excite transitions in the conjugated system, initiate unique photochemical changes, or generate free radical intermediates, participate in subsequent free radical reactions, and construct complex organic structures.
In terms of thermal stability, due to the rigidity of the dibenzofuran skeleton and the bonding of iodine atoms, the compound has a certain thermal stability. At high temperatures, chemical bonds may be broken and rearranged, resulting in structural changes, but a higher temperature threshold needs to be reached.
In terms of solubility, 2-iododibenzofuran has a certain fat solubility, and has good solubility in organic solvents such as dichloromethane, chloroform, toluene, etc., but little solubility in water. Due to the non-polar nature of the molecule as a whole, it has weak interaction with water molecules.
In summary, 2-iododibenzofuran has potential application value in many fields such as organic synthesis, materials science and photochemistry due to its unique structure. Its chemical properties lay the foundation for many reactions and applications.

The method of making 2-iododibenzofuran has been around since ancient times, and it relies on all kinds of ingenious chemical techniques. One method can be started by dibenzofuran and iodine atoms can be introduced through halogenation reaction. This halogenation technique requires careful selection of agents and temperature control to achieve the purpose of optimal yield and high purity. Iodide is often used as the iodine source, such as potassium iodide, supplemented by suitable catalysts to make the reaction smooth.
In the reaction system, the choice of solvent is also the key. Selecting a good agent can help the reactants to be miscible and promote the reaction. Common organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., have been tried. Among them, dichloromethane has good solubility and volatility, which is convenient for subsequent separation; although N, N-dimethylformamide has a high boiling point, it dissolves well for the reactants under certain reaction conditions, and can be broken down according to the specific reaction situation.
The control of temperature and time is also related to success or failure. The halogenation reaction requires a suitable temperature, which should not cause side reactions to cluster too high, nor should it be too low to slow down the reaction. Taking a method as an example, the reaction is initiated in an ice bath or at low temperature, and when the reactants are initially used, they are gradually warmed to room temperature or slightly higher, and the holding number can be obtained.
In addition, other iodine-containing reagents, such as iodoyl chloride, are also used for halogenation. Iodoyl chloride has a high activity and a fast reaction rate. However, due to its activity, it needs to be handled with caution to prevent accidents. And when using such reagents, the post-processing steps may be more complicated, and multiple processes such as washing, drying, and column chromatography are required to remove impurities and purify the product. In this way, 2-iodibenzofuran can be obtained through various delicate steps.

The price range of 2-iodibenzofuran in the market is difficult to determine. This is due to the interaction of many factors, resulting in fluctuations in its price state.
First, the complexity of the preparation process is related to the cost, which in turn affects the price. If the preparation requires a multi-step reaction, and the conditions are harsh, and special reagents and equipment are required, the cost will rise and the price will be high; if the process is simple, the cost will decrease and the price may be low.
Furthermore, the market supply and demand situation has a great impact. If the industry has a strong demand for 2-iodibenzofuran, such as in medicine, material synthesis and other fields, the application is wide and the dosage is increased, but the supply is limited, according to the reason of supply and demand, the price will rise; on the contrary, if the demand is weak and the supply is sufficient, the price may fall.
In addition, the cost of raw materials is also the key. The price fluctuation of raw materials required for its preparation is directly related to the cost of 2-iodibenzofuran. The price of raw materials is high, and the price of finished products is difficult to lower; the price of raw materials decreases, so there is room for price reduction.
From the perspective of past market conditions, the price of 2-iodibenzofuran may change due to differences in quality and High purity is mostly used for high-end scientific research and pharmaceutical research and development, and the price may range from tens to hundreds of yuan per gram; ordinary purity is used for general industrial synthesis, and the price may be relatively low, ranging from a few to tens of yuan per gram. However, this is only a rough range, and changes in real time with market dynamics. The specific price depends on the current market consultation with various suppliers.