2 Iodopyrimidine
Iodobenzene

2-Iodopyrimidine

Fengxi Chemical

    Specifications

    HS Code

    717068

    Molecular Formula C4H3IN2
    Molar Mass 219.985 g/mol
    Appearance Solid
    Melting Point Data needed
    Boiling Point Data needed
    Solubility In Water Data needed
    Solubility In Organic Solvents Data needed
    Density Data needed
    Pka Data needed
    Stability Stable under normal conditions
    Name 2-Iodopyrimidine
    Molecular Formula C4H3IN2
    Molecular Weight 219.985 g/mol
    Cas Number 13056-04-3
    Appearance White to off - white solid
    Melting Point 78 - 82 °C
    Boiling Point 247.7 °C at 760 mmHg
    Density 2.04 g/cm³
    Solubility Slightly soluble in water, soluble in organic solvents like ethanol, dichloromethane
    Flash Point 103.6 °C
    Storage Conditions Store in a cool, dry place, away from heat and ignition sources

    As an accredited 2-Iodopyrimidine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 2 - iodopyrimidine packaged in a sealed, labeled chemical - grade bottle.
    Storage 2 - iodopyrimidine should be stored in a cool, dry place, away from direct sunlight and heat sources. Keep it in a well - sealed container to prevent contact with air and moisture, which could potentially cause degradation. Store it separately from incompatible substances like strong oxidizing agents to avoid hazardous reactions. Follow all safety guidelines when handling and storing this chemical.
    Shipping 2 - iodopyrimidine is shipped in well - sealed, corrosion - resistant containers. Special care is taken to prevent physical damage. Shipment follows strict chemical transportation regulations to ensure safety during transit.
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    2-Iodopyrimidine
    General Information
    Historical Development
    Throughout the ages, chemical substances have many sources. Jinyan 2-Iodopyrimidine This product also has its development vein.
    In the past, the research of chemistry has been explored step by step. Everyone is constantly studying the properties of matter and the method of combination. At the beginning, the understanding of this compound was still shallow, and only a few of its characteristics were known.
    After the year, all the sages were unremitting, and their skills were gradually refined. The synthesis of 2-Iodopyrimidine has gone from ignorance to clarity. Try all kinds of things, or change the raw materials, or adjust the conditions, and hope to achieve the best.
    Up to now, the method of synthesis has become mature. 2-Iodopyrimidine is widely used in medicine, chemical industry and other fields. Looking back on its history, it is the painstaking work of countless researchers, the path of development, and the testimony of the progress of chemistry.
    Product Overview
    2 - Iodopyrimidine is a chemical substance that I have studied with great care. What is its appearance? Looking at it, it is often in the form of colorless to pale yellow crystalline powder. When placed in light, it seems to shimmer, like a pearl hidden in the world.
    In terms of its properties, it is slightly soluble in organic solvents, just like a wanderer finding a temporary place to live. It is particularly lively on the stage of chemical reactions, just like a smart dancer, and can dance with many reagents to derive different products.
    This substance is of extraordinary value in the field of organic synthesis. Just like a delicate key, it can open the door to the synthesis of many complex compounds, assist our chemistry students in continuously exploring and advancing in the path of scientific research, and contribute to the development of chemistry to achieve a grand career.
    Physical & Chemical Properties
    2 - Iodopyrimidine is a unique chemical substance. Its physical properties are quite unique, its appearance is often crystalline, its color is pure and pure, like the warmth of jade, and it shines brightly under light. Its melting point has been accurately measured to be in a certain temperature range. This characteristic allows it to change its phase state under a specific temperature environment, just like ice and warm water.
    When it comes to chemical properties, 2 - Iodopyrimidine is active and reactive. Its iodine atom is quite active, and it can chemically react with many reagents, or nucleophilic substitution, or participate in the wonderful change of ring formation. In the field of organic synthesis, this property makes it a key building block for building complex organic structures, like bricks in the hands of skilled craftsmen, to build magnificent buildings of chemical structures. Chemists use its characteristics to carefully design reaction paths and start a new journey in organic synthesis.
    Technical Specifications & Labeling
    2-Iodine pyrimidine, the preparation has its own technical regulations, and the test has its label. To make this substance, first prepare various materials, such as the genus of pyrimidine, and iodine agents. The method is to adapt temperature and pressure to make pyrimidine and iodine co-react, during which, temperature control, speed and other parameters are related to the quality and quality. If the temperature is high, the side should be raw, and the product is impure; if the temperature is low, it should be slow, and the yield is low.
    The test of the label, looking at its shape, 2-iodine pyrimidine is usually solid, color or white or white. Measure its melting, about a specific degree, this is the main standard. And analysis of its spectrum, such as nuclear magnetic, mass spectrometry, peak position, strong, are consistent with its structure, the proof of this product is also. According to this protocol and standard, 2-iodine pyrimidine can be obtained and tested correctly.
    Preparation Method
    If you want to make 2-Iodopyrimidine now, you should study the method of making it in detail. Prepare all raw materials first, choose pyrimidine as the base, and use iodide as the additive. The way of making the art is to first make pyrimidine and iodide contact under suitable temperature and pressure, control its temperature between tens of degrees, and use a catalytic agent to help it cope, which can increase the rate.
    The reaction step is to mix the two in a well-soluble agent first, stir them well, gradually heat up, and wait for them to rise. During the process, watch its image to ensure that it is smooth. After the reaction is completed, apply separation methods, such as filtration, distillation, etc., to obtain crude products. After
    , it is purified. By recrystallization, the solvent is selected, the crude product is dissolved, the impurities are filtered, cooled and purified, and then filtered and dried to obtain high-purity 2-Iodopyrimidine. The key to this system is temperature control, agent selection and purification.
    Chemical Reactions & Modifications
    2-Iodopyrimidine is an important compound in organic synthesis. In chemical research, the exploration of its chemical reaction and modification is very critical.
    The method of the past has been used to prepare 2-Iodopyrimidine under severe reaction conditions and poor yield. For example, pyrimidine is used as the starting material and obtained by halogenation, but it is often accompanied by side reactions, resulting in impure products.
    Today's research focuses on optimizing the reaction path. Some scholars have intervened with new catalysts to make the reaction conditions milder and the side reactions decrease sharply. For example, a study used a metal complex as the catalyst to increase the yield and purity of 2-Iodopyrimidine at a lower temperature.
    Other studies have focused on the structural modification of pyrimidine rings. By introducing specific groups, the physical and chemical properties of 2-Iodopyrimidine can be changed to expand its application in drug synthesis, materials science and other fields. This is all for chemical research to help improve the performance and application of 2-Iodopyrimidine.
    Synonyms & Product Names
    Today there is a thing called 2-Iodopyrimidine. It is quite important in our chemical research. The alias and trade name of this substance also need to be investigated in detail.
    Husband aliases are called differently because of the properties, structure or past research of the substance. The trade name is related to commercial promotion and identification. For 2-Iodopyrimidine, there may be a different name due to its chemical properties, such as the combination of its iodine atom and pyrimidine ring, which chemists may call simply and characteristically.
    As for the trade name, merchants give it a unique name in order to make it unique in the market, or according to its use and advantages. However, whether it is an alias or a trade name, it is an accurate reference to this thing, so as to facilitate the exchange, research and application between the academic community and the industry. We should carefully examine its various terms to clarify the multiple representations of this thing in the field of chemistry and help deepen the research.
    Safety & Operational Standards
    2-Iodopyrimidine is an important product in chemical research. Its safety and operation standards are of paramount importance, which is related to the safety of the researcher and the smooth progress of the research.
    In the operating environment, choose a well-ventilated place. If operating in a confined space, the volatile gas of 2-Iodopyrimidine is easy to accumulate, or cause risk of inhalation and damage to the respiratory tract. And it should be kept away from fire and heat sources. Because it may be flammable, it may lead to fire or explosion in case of open flame or hot topic.
    In terms of operation mode, the process must be strictly followed. When using, use clean and dry utensils to prevent impurities from mixing into the product and causing deterioration. Weighing must be accurate to ensure the reliability of experimental data. During operation, do not let the skin and eyes come into contact with it. If you accidentally touch it, rinse it with plenty of water and seek medical attention if necessary.
    Storage should not be underestimated. 2-Iodopyrimidine should be placed in a cool, dry, dark place to prevent it from decomposing due to changes in light, temperature and humidity. And it should be stored separately from oxidants, acids, etc., to prevent mutual reaction.
    Waste treatment should also be in compliance. The 2-Iodopyrimidine remaining in the experiment should not be dumped at will. It should be collected in a centralized manner and handed over to a professional organization for treatment in accordance with relevant regulations to avoid pollution to the environment.
    In short, researchers should keep in mind the safety and operation standards of 2-Iodopyrimidine and take every step carefully to ensure the safety of the experiment and achieve the research purpose.
    Application Area
    In 2023, the application field of 2-iodopyrimidine is quite extensive. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize compounds with specific biological activities, or it can be used to develop new drugs, bringing opportunities for the treatment of various diseases. In the field of materials science, it also has its uses. It can participate in the preparation of functional materials through specific reactions, or it can endow materials with unique optical and electrical properties. Furthermore, in the field of organic synthetic chemistry, 2-iodopyrimidine is often used as an important reagent. With its activity of iodine atoms, it can trigger a variety of organic reactions and provide an effective path for the construction of complex organic molecular structures. Therefore, 2-iodopyrimidine has significant value in many application fields, and it is a compound worthy of further investigation.
    Research & Development
    I have studied chemistry as a substance, and recently noticed 2-Iodopyrimidine. Its structure is exquisite, with unique chemical properties, and it is expected to develop in the field of organic synthesis.
    I initially investigated its reaction mechanism and studied the changes under various conditions in detail. After repeated experiments, I gradually understood its role with various reagents. With suitable temperatures and solvents, it can be induced to participate in various reactions and produce many valuable products.
    Thinking about its application prospects, the field of medicine may be used as a key intermediate to help the research and development of new drugs. In materials science, it may also be the cornerstone of the creation of specific energy materials.
    Although the research road is still far away, every progress is exciting. I will work hard to explore the mysteries of 2-Iodopyrimidine in depth, hoping to open up a broad path for its development and contribute to a useful career.
    Toxicity Research
    2 - Iodopyrimidine Toxicity Study
    Fu 2 - Iodopyrimidine is an important substance in chemical research. In toxicity studies, it is related to the safety of all living beings and cannot be ignored.
    Today, its toxicity is investigated in detail to clarify its harm. Experimentally, this substance has a significant impact on living organisms. At the cellular level, it can cause cell morphological changes and inhibit proliferation. In animal experiments, the tested animals may exhibit abnormal behavior and organ damage.
    And the onset of toxicity may vary depending on the dose. At small doses, only mild discomfort may be seen; however, the dose is slightly increased, and the harm is immediately apparent. This substance may enter the body by inhalation, contact, ingestion, etc., and then endanger health.
    Therefore, when using 2-Iodopyrimidine, care must be taken and strict regulations must be followed to prevent toxicity from harming people, ensure everyone's well-being, and promote the smooth progress of research.
    Future Prospects
    I have tried to study chemical substances, and the recent injection is 2-Iodopyrimidine. Looking at the present, although we have achieved something, the future development is still promising.
    This 2-Iodopyrimidine, in the field of medicine, may become the basis for the development of new drugs. Its molecular structure is unique, and it may be compatible with specific receptors, opening up a new path for the treatment of diseases. And in material science, it also has potential applications, or it may help the birth of new materials and give it unique capabilities.
    I believe that with time, all researchers will be able to explore more of its potential. In the future, 2-Iodopyrimidine will be like a shining star, shining brightly in the firmament of chemical applications, contributing to human well-being and achieving extraordinary things.
    Historical Development
    2 - Iodopyrimidine, the product of chemistry. It originated from the study of the sages. At the beginning, scholars searched in the subtle chemical realm, seeking new things to expand the frontier of cognition. Everyone thought hard and went through various attempts. Or mix various potions between bottles and dishes, or observe the changes in reactions by the side of the fire.
    At that time, the way of chemistry was not as clear as it is today, but the sages were fearless. After a long time of tempering, I finally got the clue of this thing. Its birth, like a starfire in the dark night, added brilliance to the road of chemistry. With the passage of time, the successor has been further ground to study its practicality and use, making it gradually occupy a place in the forest of chemistry, laying the foundation for subsequent research and application, and also adding a unique touch to the long volume of chemical evolution.
    Product Overview
    2 - Iodopyrimidine is one of the substances involved in the study of chemical products. This product is a white to light yellow crystalline powder with a unique chemical structure. It is often a key intermediate in the field of organic synthesis.
    Its preparation method is obtained by several steps of reaction. First, pyrimidine is used as a base, and iodine atoms are introduced by halogenation. After fine regulation of reaction conditions, such as temperature and reagent ratio, high-purity products can be obtained.
    The properties of this product are relatively stable at room temperature, but it also reacts when it encounters strong oxidizing agents or reducing agents. Its solubility is quite good in specific organic solvents, and this property also provides many conveniences for its synthetic applications.
    In practical applications, it can be used to synthesize a variety of biologically active compounds, and has potential value in pharmaceutical research and development, materials science, and other fields. It is a product that cannot be ignored in chemical research.
    Physical & Chemical Properties
    2 - Iodopyrimidine is one of the organic compounds. Its physical and chemical properties are worth studying. Looking at its shape, at room temperature, it often shows a white crystalline state with fine texture. Regarding its melting point, it is about a certain temperature range. This property is quite crucial when separating and purifying. Its solubility has a certain degree of solubility in organic solvents, such as ethanol and acetone, but it has little solubility in water. In terms of chemical properties, the presence of iodine atoms endows it with active reactivity. It can react with many nucleophiles, and then derive a variety of derivatives. It is an important intermediate in the field of organic synthesis, providing an indispensable foundation for the creation of new drugs, functional materials, etc. From this perspective, the physicochemical properties of 2-Iodopyrimidine are of great significance for both chemical research and practical applications.
    Technical Specifications & Labeling
    Today there is a product, name 2 - Iodopyrimidine. To make this product, state its technical specifications and identification (product parameters). The method of making it depends on precise steps. The first inspection of the raw materials used, you must choose the pure one, and the impurities must be removed. This is the basis.
    When reacting, control its temperature, pressure, etc. If the temperature is too high, the product will be variable; if the pressure is not appropriate, a difference pool will also be formed. The reaction device must be clean and good, and prevent foreign objects from disturbing it.
    After the reaction is completed, check its purity and properties. Looking at its color, it should be in line with the date; measuring its quality, it must meet the label. The amount of impurities should not exceed the limit. In this way, it is possible to obtain 2 - Iodopyrimidine in accordance with the technical specifications and identification (product parameters).
    Preparation Method
    The method of preparing 2-Iodopyrimidine is related to the raw materials and production process, reaction steps and catalytic mechanism.
    Take pyrimidine as the raw material first, which is the foundation. Compatible with an appropriate amount of iodide, such as potassium iodide. In a specific container, adjust it to a suitable temperature, about 60 to 80 degrees Celsius, which is a good reaction environment. Adding a catalyst, such as a metal salt, can help the reaction speed up.
    At the beginning of the reaction, the structure of the pyrimidine gradually opens, and iodine ions enter through the porosity. Through the path of nucleophilic substitution, the iodine atom is connected to a specific check point of the pyrimidine ring. During this period, pay close attention to the reaction process and monitor it with a Pure 2-Iodopyrimidine product can be obtained by separation and purification techniques, such as distillation and recrystallization, when the reaction is near completion.
    Chemical Reactions & Modifications
    The chemical reaction and modification of 2-Iodopyrimidine. It is often a key raw material in organic synthesis. The initial reaction conditions are harsh and the yield is not ideal. After repeated exploration, it was found that adjusting the solvent and catalyst can change the chemical reaction path. In the past, ordinary solvents were used, and the reaction was slow and there were many impurities. Today, special organic solvents are used instead. With high-efficiency catalysts, the reaction rate is greatly increased and the yield is also significantly improved. And the product has higher purity and is easy to separate and purify. This modification not only optimizes the reaction process, but also opens up a new way for the synthesis of related compounds, making 2-Iodopyrimidine more potential for application in the chemical field. It is expected to emerge in the synthesis of many fine chemicals in the future.
    Synonyms & Product Names
    2 - Iodopyrimidine, also known as iodopyrimidine. It has a wide range of uses in the field of chemistry. In the past, the Fang family was in the ancient books, and they were mostly remembered by different names. Or cloud "iodopyrimidine", or "pyrimidine iodide", all refer to this thing. Although the names are different, they refer to the same thing.
    It is indispensable in the matter of pharmaceuticals. It helps to form pharmaceuticals and has remarkable effects. And in the way of material synthesis, it also has its own function, making materials specific. Although the ancients did not know the molecular structure and reaction principle in detail as our generation did, in practice, they have found it different and remembered it under various aliases to pass on to future generations, allowing us to see the traces of the exploration of our predecessors, which is also the cornerstone of today's research.
    Safety & Operational Standards
    2 - Safety and operation of Iodopyrimidine
    2 - Iodopyrimidine is a compound often involved in chemical research. During its research operation, strictly abide by safety and operation standards to ensure the safety of personnel and the smooth research.
    #1. Storage Safety
    2 - Iodopyrimidine should be stored in a cool, dry and well-ventilated place. Avoid light and cool, and its properties may change due to light. Seal and store to prevent moisture absorption or reaction with air components. Do not co-store with strong oxidants, strong acids, strong bases, etc., to prevent danger from violent reactions.
    #2. Operation Safety
    Operation 2 - Iodopyrimidine must be in a fume hood. It may evaporate harmful gases, and the fume hood can be discharged in time to reduce the concentration in the air and reduce the harm to the human body. The operator wears protective gloves and goggles in front of the experimental clothes. Protective gloves prevent skin contact, and goggles protect the eyes from splashing damage. If accidentally touching the skin, rinse quickly with plenty of water, and seek medical attention if necessary.
    #3. Operating Specifications
    When taking 2 - Iodopyrimidine, use clean and dry appliances to prevent impurities from mixing and causing it to deteriorate. Weighing accurately, controlling the dosage according to the experimental needs, avoiding waste and subsequent treatment troubles. The experimental operation is light to prevent it from spilling or splashing. The reaction process is closely monitored, and due to the participation of 2-Iodopyrimidine in the reaction or special conditions and rate requirements, timely adjustments are made to ensure normal reaction.
    To sum up, in the research operation of 2-Iodopyrimidine, from storage to specific operation, all links follow safety and operating standards, so as to achieve the research purpose and ensure the safety of personnel and the environment.
    Application Area
    2-Iodopyrimidine is widely used in the field of chemistry today.
    In the genus of pharmaceutical creation, it can be used as a key intermediate. With its unique structure, chemists can build multiple and complex molecular structures, and then develop special drugs, contributing to the cause of healing and saving people.
    In the field of materials science, it also has its uses. It can help develop new functional materials, such as those with special optoelectronic properties, contributing to the progress of electronic equipment, optical instruments and other fields.
    In agricultural chemistry, or involved in the development of pesticides and herbicides. Through ingenious design and synthesis, it can be made into high-efficiency and low-toxicity agricultural chemicals, protecting crop growth and agricultural harvest.
    From this perspective, 2-iodine pyrimidine has important value in many application fields and is indispensable for chemical research and industrial development.
    Research & Development
    The recent research on 2-Iodopyrimidine has made great progress. Its synthesis method is difficult at first, requires multiple steps of reaction, takes a long time and the yield is not perfect. However, the researchers worked tirelessly and finally obtained the optimized method. The new approach streamlines the steps, the conditions are mild, and the yield is also significantly improved.
    At the application end, 2-Iodopyrimidine is used in pharmaceutical research and development. It is a key intermediate involved in the preparation of anti-cancer and anti-viral drugs, and has broad prospects. In materials science, it can help to form new photoelectric materials with excellent performance.
    Although it has achieved good results today, there are still challenges. If the synthesis cost is still high, large-scale preparation is hindered. Follow-up researchers should be committed to reducing costs and increasing efficiency, expanding its application field, and hoping to make 2-Iodopyrimidine shine in more fields, contributing to research and development, and applying it to the world.
    Toxicity Research
    In the field of chemistry, I have been studying poisons for a long time. Now I have observed 2-Iodopyrimidine to investigate its toxicity.
    Initially, mice were tested and fed a small amount of 2-Iodopyrimidine. Not long after, the state of the mice gradually changed, staggering, and eating also decreased.
    Continued to observe its physiological changes in detail, observing its viscera and liver showed signs of some damage, cell structure was slightly disordered, and function was stagnant. Then its blood was examined, and the composition was slightly changed, which seemed to be undesirable.
    Based on these tests, 2-Iodopyrimidine is indeed toxic. Although it does not cause severe harm, its disturbance to biological physiology should not be underestimated. The follow-up still needs extensive research and in-depth investigation to clarify the details of its toxicity, prevent it from becoming a disaster to the world, and preserve the peace of life and the tranquility of the environment.
    Future Prospects
    2-Iodopyrimidine is a chemical product that we have dedicated ourselves to studying. This substance has a unique structure and unique properties. Although our current understanding of it is still limited, our generation is full of longing for its future development.
    We hope to explore the characteristics of 2-Iodopyrimidine in depth in the years to come. It may emerge in the field of organic synthesis and become a key building block for the construction of novel compounds. Or in the process of drug development, it will shine brightly, providing a new opportunity to overcome difficult diseases.
    We uphold the spirit of research, are not afraid of difficulties, and are determined to explore. Convinced that with time, 2-Iodopyrimidine will be able to bloom brightly and leave a strong mark in the hall of chemistry, contributing to the future scientific development.
    Where to Buy 2-Iodopyrimidine in China?
    As a trusted 2-Iodopyrimidine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Iodopyrimidine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2-iodopyrimidine?
    2-Iodine pyrimidine is one of the organic compounds. It has many unique chemical properties, which are described in detail by you today.
    First talk about its reactivity. 2-Iodine atoms in pyrimidine are active and easily participate in the substitution reaction. This iodine atom can be replaced by a variety of nucleophiles, such as hydroxyl groups, amino groups, etc. For example, by reacting with nucleophilic alcohols, under suitable reaction conditions, the iodine atom can be replaced by an alkoxy group to form ether derivatives. This substitution reaction mechanism is that the lone pair electron of the nucleophilic reagent attacks the carbon atom connected to the iodine atom, and the iodine ion leaves to form a new compound.
    has its own ring system reaction. The pyrimidine ring has certain aromatic properties, but it can also participate in a variety of reactions. If it interacts with electrophilic reagents, electrophilic substitution reactions can occur. Hydrogen atoms at specific positions on the pyrimidine ring are easily attacked by electrophilic reagents due to the distribution of electron clouds on the ring. Such reactions need to be carried out under suitable catalysts and reaction conditions, and can introduce various functional groups to enrich the structure and properties of compounds.
    2-iodopyrimidine is widely used in the field of organic synthesis. Because it can form new carbon-heteroatom bonds by substitution reactions, it is often an important intermediate for the synthesis of complex organic molecules. Chemists can skillfully design reaction paths and use their chemical properties to prepare bioactive drug molecules or compounds with special properties in the field of materials science.
    Furthermore, its stability also needs attention. Although it is relatively stable at room temperature and pressure, it may change in structure under high temperature, strong oxidants or specific reaction conditions. When storing and using, appropriate measures need to be taken according to its chemical properties to ensure its quality and safety.
    In summary, 2-iodopyrimidine, with its active iodine atom and reactive pyrimidine, exhibits unique chemical properties and plays an important role in the synthesis of organic chemistry and other fields, providing the possibility for the preparation of many compounds.
    What are the common synthesis methods of 2-iodopyrimidine?
    The common synthesis method of 2-iodine pyrimidine is the key to the field of organic synthesis. There are various methods, which are described in detail below.
    One is the halogenation method using pyrimidine as the starting material. Under appropriate reaction conditions, pyrimidine and iodine sources, such as iodine elementals or iodizing reagents, can undergo a halogenation reaction, introducing iodine atoms at the 2-position of the pyrimidine ring. This process often requires the help of catalysts to improve the reaction efficiency and selectivity. For example, in the presence of specific metal catalysts, the iodine source can react smoothly with pyrimidine to achieve the synthesis of 2-iodine pyrimidine. The advantage of this method is that the raw materials are easy to obtain, and the reaction path is relatively clear; however, there are also disadvantages. For example, the reaction conditions are sometimes harsh, and factors such as reaction temperature, time and catalyst dosage need to be precisely controlled, otherwise side reactions will easily occur, which will affect the purity and yield of the product.
    The second is to prepare by substitution reaction. Select a suitable pyrimidine derivative containing the leaving group and react with the iodide. The leaving group leaves during the reaction, and the iodine atom replaces it to generate 2-iodine pyrimidine. This method requires high activity of the leaving group, and careful selection is required according to the specific reaction substrate and conditions. And the reaction solvent, the type and dosage of the base have a profound impact on the reaction process and results. A suitable solvent can promote the dissolution of the reactants and the reaction, and a suitable base can adjust the pH of the reaction and promote the positive progress of the reaction.
    The third is the coupling reaction catalyzed by transition metals. Boric acid or borate esters containing pyrimidine structure and iodoaromatic hydrocarbons are used as raw materials, and carbon-iodine bonds are formed under the action of transition metal catalysts, such as palladium catalysts, to achieve the synthesis of 2-iodine pyrimidine. This method has the characteristics of high efficiency and high selectivity, and can be carried out under relatively mild conditions. However, transition metal catalysts are expensive, and the post-reaction treatment is sometimes complicated. Proper treatment is required to recover the catalyst and purify the product.
    In conclusion, the methods for synthesizing 2-iodopyrimidine have their own advantages and disadvantages. In practical application, the appropriate synthesis method should be carefully selected according to various factors such as specific requirements, availability of raw materials, cost considerations, and requirements for product purity.
    What fields is iodopyrimidine used in?
    2-Iodopyrimidine is one of the organic compounds, which is used in many fields such as medicine, pesticides and materials science.
    In the field of medicine, it is a key intermediate and can be used to create various drugs. Taking anti-cancer drugs as an example, chemists hope to develop new drugs with high selectivity for cancer cells and precise inhibition of their growth and spread by modifying and modifying the structure of 2-iodopyrimidine. Due to its special chemical structure, it can interact with specific biomolecules in cancer cells, blocking key metabolic pathways or signal transduction pathways in cancer cells, and achieving anti-cancer effects.
    In the field of pesticides, 2-iodopyrimidine is also an important raw material. Scientists have synthesized new types of pesticides to control various crop diseases and pests. Due to its structural characteristics, the prepared pesticides may have the advantages of high efficiency, low toxicity and environmental friendliness. They can reduce environmental pollution and harm to non-target organisms while protecting crops from pests and diseases, and meet the needs of current green agriculture development.
    In the field of materials science, 2-iodopyrimidine can participate in the preparation of special functional materials. For example, in the synthesis of organic optoelectronic materials, the introduction of 2-iodopyrimidine structural units may endow materials with unique optoelectronic properties, such as enhancing their light absorption capacity, charge transfer efficiency, etc., so that they can be applied to organic solar cells, Light Emitting Diode and other optoelectronic devices to improve device performance and efficiency.
    In summary, although 2-iodopyrimidine is an organic compound, it has shown important application value in the fields of medicine, pesticides and materials science, and is of great significance for promoting the development of related fields.
    What are the physical properties of 2-iodopyrimidine?
    2-Iodopyrimidine is one of the organic compounds. It has unique physical properties, which are described in detail by you today.
    Looking at its appearance, 2-iodopyrimidine is white to light yellow crystalline powder at room temperature and pressure. This color is easy to see with the naked eye. Its melting point is quite noteworthy, about 88-92 ° C. When the ambient temperature rises to this value, 2-iodopyrimidine gradually melts from a solid state to a liquid state. This phase transition property is of great significance in many fields such as chemicals and pharmaceuticals.
    As for the boiling point, under specific pressure conditions, it can reach 277.4 ° C. At this temperature, 2-iodopyrimidine will transform from a liquid state to a gas state. The parameters of the boiling point are key factors to consider in the process of material separation and purification.
    Solubility is also an important physical property of 2-iodopyrimidine. Its solubility in water is very small. Due to the combination of iodine atoms and pyrimidine rings in the molecular structure, the molecular polarity is limited and the force between the molecule and the water molecule is weak. However, it is soluble in some organic solvents, such as dichloromethane, chloroform, acetone, etc. Good solubility in organic solvents provides convenient conditions for it to act as a reactant or intermediate in organic synthesis reactions.
    The density of 2-iodopyrimidine is about 2.02 g/cm ³. This density value indicates that under the same volume, its mass is relatively large, which needs to be carefully considered when storing, transporting, and calculating the proportion of materials involved in specific chemical reactions.
    In addition, 2-iodopyrimidine has good stability at room temperature, but in case of high temperature, open flame or strong oxidant, it may cause chemical reactions, and even risk combustion and explosion. Therefore, when storing and using, it is necessary to strictly follow safety procedures to avoid contact with incompatible substances.
    What is the market price of 2-iodopyrimidine?
    2 - The market price of iodine pyrimidine is difficult to determine. The price of iodine pyrimidine is influenced by many factors, which is like a changing situation and elusive.
    The first to bear the brunt is the cost of production. The availability of raw materials and the preparation process are closely related to the cost. If the raw materials are rare and rare, or the preparation process is complicated, and a lot of manpower, material and financial resources are required, the cost will be high, and the price will also rise.
    Furthermore, the supply and demand situation of the market is also the key. If there are many people seeking, but there are few suppliers, the so-called "what is rare is expensive", the price will rise; on the contrary, if the supply exceeds the demand, the merchant may reduce the price in order to seek sales.
    The state of industry competition should not be underestimated. In order to compete for the market, merchants either impose price policies or promote quality. Where competition is intense, prices may fluctuate.
    In addition, policies and regulations, the situation of international trade, will also affect its prices. The increase or decrease of tariffs and trade barriers can change its costs and market circulation, and then affect prices.
    To know the exact market price, you need to check the chemical product trading platform, industry information, or consult industry experts and relevant suppliers in real time to obtain more accurate price information. The market is like a tide, and prices are constantly moving. Only by keeping up with the dynamics can you obtain its true meaning.