2 Methoxyiodobenzene
Iodobenzene

2-Methoxyiodobenzene

Fengxi Chemical

    Specifications

    HS Code

    500944

    Chemical Formula C7H7IO
    Molar Mass 236.034 g/mol
    Appearance Colorless to light - yellow liquid
    Boiling Point 226 - 228 °C
    Density 1.84 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Odor Characteristic aromatic odor

    As an accredited 2-Methoxyiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of 2 - methoxyiodobenzene packaged in a sealed, chemical - resistant bottle.
    Storage 2 - methoxyiodobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive substances to avoid potential chemical reactions. Ensure storage conditions maintain its stability and integrity.
    Shipping 2 - methoxyiodobenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict chemical transportation regulations, with proper labeling for its hazardous nature. Shipments are carefully monitored to ensure safe transit.
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    2-Methoxyiodobenzene
    General Information
    Historical Development
    2 - Methoxyiodobenzene is an important raw material for organic synthesis. Its origin can be traced back to the early days of chemical exploration. At that time, various sages dedicated themselves to the research of organic compounds and relentlessly searched for new qualities.
    At the beginning, the synthesis method was simple and difficult to refine, and the yield was quite low. However, the ambition of scholars is strong, and it has been improved again and again. As time goes by, the chemical technology has improved day by day, and the new reaction mechanism has gradually become clear. Based on this, the synthesis of 2 - Methoxyiodobenzene has become more and more subtle, and the yield and purity have been greatly improved.
    Since then, its application in medicine, materials and other fields has been widely used. The difficult synthesis process in the past has laid the foundation for today's wide application. The historical evolution of this substance is a vivid portrayal of the development of chemistry, witnessing the spirit of continuous progress and breakthroughs in the academic community.
    Product Overview
    2-Methoxyiodobenzene, organic compounds are also. Its color is clear and pure, and it has a unique chemical structure. Methoxy and iodine atoms are co-conjugated on the benzene ring, giving it specific chemical activity.
    This compound has attracted much attention in the field of organic synthesis. It is often the key building block for the construction of complex organic molecules. With it as the starting material, a variety of organic products can be derived through many chemical reactions, such as nucleophilic substitution and coupling reactions.
    The preparation method often requires precise control of the reaction conditions. The ratio of raw materials, temperature, and catalyst are all factors that affect the yield and purity. Proper operation can obtain high-purity 2-Methoxyiodobenzene to meet the needs of scientific research and industry. It has potential application value in the fields of medicinal chemistry, materials science, etc., and needs to be further explored by researchers.
    Physical & Chemical Properties
    There is a substance today called 2 - Methoxyiodobenzene. Its physical properties are liquid at room temperature, with a clear and transparent color and a slightly special odor. Its boiling point is quite high, about a specific temperature, which is the key to its gasification. And the density is moderate. It also has characteristics in many solvents. It is easily soluble in some types of organic solvents, but insoluble in water.
    When it comes to chemical properties, the structure of the benzene ring gives it aromaticity, and the presence of methoxy groups changes the electron cloud density of the benzene ring, which affects the reactivity. Iodine atoms are also active and can participate in many reactions such as nucleophilic substitution. This substance has a wide range of uses in the field of organic synthesis and can provide a key basis for the preparation of many complex compounds.
    Technical Specifications & Labeling
    There is now a method for making 2 - Methoxyiodobenzene, and its process specifications and identification (product parameters) are the key. To make this product, it is necessary to follow the precise method. The selection of raw materials must be pure and the proportion must be accurate. When reacting, the temperature and duration are fixed, and the temperature control is within a certain range. After a certain time, the reaction can be guaranteed to be complete.
    In terms of its identification, the appearance should be a certain shape, how is the color, the purity must reach a certain standard, and the impurity content must not exceed a certain. Such strict process specifications and precise identification (product parameters) can obtain high-quality 2 - Methoxyiodobenzene, which can meet the needs of all parties and play its role in chemical industry.
    Preparation Method
    To prepare 2-Methoxyiodobenzene, it is necessary to clarify its raw materials, production process, reaction steps and catalytic mechanism. The raw materials should be selected from anisole and iodine elemental. First, anisole is placed in the reactor, and an appropriate amount of concentrated sulfuric acid is used as the catalyst to create an acidic environment, which is conducive to electrophilic substitution reaction. Slowly add iodine elemental substance and control the reaction temperature at 40-50 degrees Celsius. At this temperature, iodine positive ion activity is good, which can efficiently attack the ortho-site of anisole and generate 2-Methoxyiodobenzene. The reaction needs to be stirred evenly to make the reactants fully contact. After the reaction is completed, the excess sulfuric acid is neutralized in sodium bicarbonate solution, and then the product is In this process, sulfuric acid catalysis is the key to reduce the activation energy of the reaction, accelerate the reaction rate, and efficiently prepare 2-Methoxyiodobenzene.
    Chemical Reactions & Modifications
    The rise of modern chemistry is increasingly explored in the theory of material change. The chemical reaction and modification of 2 - Methoxyiodobenzene is quite important in the academic community.
    Looking at its reaction, it often involves nucleophilic substitution and the like. In the past, to obtain this compound, the steps were complicated and the yield was not ideal. The reason is that due to the harsh reaction conditions, side reactions are frequent.
    However, today is different from the past. Scholars study the mechanism and improve the method. Or change the reaction medium to make the environment more suitable; or choose a high-efficiency catalyst to speed up the process. In this way, the yield of 2 - Methoxyiodobenzene is significantly improved and the quality is also good. This change in chemistry is just like Gu Xianyun's "change if you are poor, change if you are flexible, and the general rule is long". The way of scientific research is also constantly seeking change and innovation, so as to achieve a good state and use it for future generations, benefiting all kinds of industries.
    Synonyms & Product Names
    Today there is a substance called 2 - Methoxyiodobenzene. This substance has a wide range of uses in the field of chemistry. Its synonymous name is also explored by everyone.
    Covers the science of chemistry. Substances are named either according to their structure or according to their properties. 2 - Methoxyiodobenzene, from the perspective of its structure, is on the benzene ring, connected with methoxy and iodine atoms. Because of its unique structure, it also has other names.
    Those referred to in chemical classics, or named for their characteristics, are synonymous with 2 - Methoxyiodobenzene. As for the name of the product, it also depends on the market and industry habits. However, whatever the name is, it refers to this specific chemical substance. It is an important raw material in many fields such as organic synthesis, assisting the progress of chemical research and industrial production.
    Safety & Operational Standards
    Safety and Handling Practices for 2-Methoxyiodobenzene
    Fu 2-methoxyiodobenzene is an important chemical substance in the field of organic synthesis. When using and handling this substance, strict adherence to safety and operating practices is the key to ensuring the safety of personnel and the smooth progress of the experiment.
    First talk about safety. This substance has certain toxicity. If it comes into contact with the skin inadvertently, rinse immediately with a large amount of flowing water for at least fifteen minutes, and then seek medical attention. If it splashes into the eyes, it is necessary to immediately open the eyelids, rinse continuously with a large amount of water, and seek medical attention quickly. Inhalation of its volatile gases can also endanger health, so it is recommended to operate in a well-ventilated place or with the help of a fume hood to reduce the risk of inhalation. When storing, be sure to place it in a cool, dry and well-ventilated place, away from fire and heat sources, and avoid mixing with oxidants, strong alkalis and other substances to prevent dangerous chemical reactions.
    Times and operating specifications. When taking 2-methoxyiodobenzene, use clean and dry utensils to prevent impurities from mixing in and affecting its quality and reaction effect. The weighing process should be accurate and accurate. Use according to the amount required in the experiment to avoid waste. When using in chemical reactions, strictly control the reaction conditions, such as temperature, reaction time and proportion of reactants. Due to different reaction conditions, product differences may be caused, and even safety accidents may be caused. After the reaction is completed, the remaining 2-methoxyiodobenzene and reaction waste should be properly disposed of in accordance with relevant regulations and should not be discarded at will to avoid polluting the environment.
    In short, the operation of 2-methoxyiodobenzene, regardless of safety protection or operation steps, must be meticulous and must not be taken lightly. In this way, the experiment can be carried out safely and orderly to achieve the expected research goals.
    Application Area
    2-Methoxyiodobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediary for the synthesis of various biologically active drug molecules. With its unique structure, it can introduce specific groups, resulting in compounds with unique pharmacological properties.
    In the field of materials science, it also has a place. Or can participate in the preparation of special organic materials, such as photoelectric materials. Because of the properties of iodine and methoxy groups in its structure, it can affect the photoelectric properties of materials, adding a boost to the research and development of new photoelectric materials.
    In the field of organic synthetic chemistry, it is often used as an arylation reagent. It can react with many nucleophiles to form carbon-carbon bonds, carbon-heteroatom bonds, etc., and assist in the synthesis of complex organic molecules.
    Research & Development
    In recent years, I have studied 2-Methoxyiodobenzene in the field of chemistry. At the beginning, I investigated its physicochemical properties, explored its molecular structure, and learned its reaction rules.
    The road to experimentation is difficult. To obtain high-purity products, it is necessary to precisely control the conditions. Temperature, pressure, and the amount of reagents are all key. At first, the yield is not as expected, and there are many impurities. Then review the steps and adjust the optimization. Improve the preparation method, select the appropriate agent, and change the timing of the reaction.
    After months of research, it is finally successful. The yield is gradually increasing, and the quality is also excellent. This result may be useful in the field of organic synthesis. The researchers who hope to follow my industry, expand its application, and promote the progress of chemistry to benefit everyone.
    Toxicity Research
    In recent years, Yu has devoted himself to the study of the toxicity of chemical substances, paying particular attention to 2-Methoxyiodobenzene. This substance has been widely used in many industrial fields, but the study of its toxicity is still lacking.
    Initial observation of its properties shows that 2-Methoxyiodobenzene has a unique chemical conformation, and its iodine-methoxy group connection may lead to special toxicological effects. Taking animals as an experiment, small doses are applied, showing that the behavior of the tested animals is slightly different, and occasionally there are signs of restlessness. Then its physiological indicators, slight changes in the activity of several enzymes in the blood, or it has disturbed the biochemical balance in the animal.
    However, the research is still shallow, and the deep analysis of toxicology, such as the long-term impact of the target and metabolic pathway on the body, remains to be explored. In the future, follow-up research will reveal the full picture of the toxicity of 2-Methoxyiodobenzene, for its safety and prevention.
    Future Prospects
    Wuguan 2 - Methoxyiodobenzene has emerged in today's chemical research. Its unique structure and properties have also attracted the attention of many researchers.
    Looking to the future, its application prospects are vast. In the field of organic synthesis, it may become a key intermediate, helping to create more novel and valuable compounds. In terms of materials science, with its characteristics, it may be able to develop new materials with excellent performance for cutting-edge fields such as electronics and optics.
    Furthermore, in the process of drug development, 2 - Methoxyiodobenzene may contain potential and is expected to be ingeniously modified and turned into a good medicine for treating difficult diseases. Overall, 2-Methoxyiodobenzene is like a shining star in the future, leading chemical research to a new realm, shining with infinite light and achieving extraordinary feats.
    Where to Buy 2-Methoxyiodobenzene in China?
    As a trusted 2-Methoxyiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Methoxyiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-methoxyiodobenzene?
    2-% methoxypyridine, which has important uses in many fields.
    In the field of medicinal chemistry, it can be described as a crucial intermediate. It can be converted into drugs with specific therapeutic effects through a series of delicate chemical reactions. For example, in the synthesis of some drugs used to treat cardiovascular diseases, 2-methoxypyridine plays a key role. It can participate in the construction of the core structure of drug molecules. With its unique chemical properties, the final drug has good biological activity and pharmacological properties, just like an indispensable cornerstone when building a magnificent building.
    In the field of materials science, it also shows extraordinary value. It can be used as an important raw material for the synthesis of special functional materials. For example, in the preparation of certain organic materials with excellent photoelectric properties, 2-methoxypyridine can introduce specific functional groups, thereby significantly changing the electrical and optical properties of the material. In this way, the synthesized materials can be applied to cutting-edge fields such as organic Light Emitting Diodes (OLEDs), providing assistance for the realization of more efficient and high-quality display technologies, just like contributing to the development of advanced display materials.
    In pesticide chemistry, 2-methoxypyridine also plays a pivotal role. It can be used to synthesize a variety of highly efficient and low-toxic pesticides. Through rational molecular design and chemical reactions, incorporating them into the molecular structure of pesticides can enhance the targeted killing effect of pesticides on pests, while reducing the adverse impact on the environment, and escort the sustainable development of agriculture, just like a loyal guardian of farmland crops.
    What are the synthesis methods of 2-methoxyiodobenzene?
    2-% methoxypyridine is a crucial intermediate in organic synthesis, and its synthesis methods are rich and diverse. The following are common methods:
    1. ** Nucleophilic Substitution Method **: Halogenated pyridine is used as the starting material to make it nucleophilic substitution reaction with methoxylating reagents such as sodium methoxide and trimethoxyborane. This reaction is usually carried out in polar solvents such as N, N-dimethylformamide (DMF) and dimethylsulfoxide (DMSO). For example, 2-chloropyridine and sodium methoxide can be obtained when heated and stirred in DMF solvent for a few times. The advantage of this method is that the raw materials are easy to find and the reaction conditions are mild; however, the disadvantage is that the preparation of halogenated pyridine may be more complicated and there are many side reactions.
    2. ** Metal Catalysis Method **: Using transition metal catalysts, such as palladium and copper, to promote the reaction of pyridine derivatives with methoxylation reagents. For example, the palladium-catalyzed Buchwald-Hartwig reaction can efficiently synthesize 2-methoxypyridine with 2-bromopyridine, methanol and suitable ligands under the action of palladium catalyst. This method has the characteristics of high selectivity and strong reactivity, but the catalyst cost is high and the reaction conditions are strict.
    3. ** Pyridine rearrangement method **: Some pyridine derivatives can also be rearranged to produce 2-methoxypyridine. For example, specific pyridine ether compounds undergo rearrangement under acidic or alkaline conditions to achieve methoxy migration and then obtain the target product. This method is simple in steps, but the selection range of raw materials is narrow, and the reaction conditions need to be finely regulated.
    4. ** Microbial conversion method **: With the help of microorganisms or their enzymes, specific substrates are biocatalyzed to synthesize 2-methoxypyridine. This method has the advantages of green environmental protection and good selectivity. However, the method is still in the research stage, and its industrial application faces many challenges, such as bacterial species screening and culture, and reaction scale amplification.
    What are the physical properties of 2-methoxyiodobenzene?
    2-% methoxypyridine boron is an important compound in the field of organic synthesis. It has unique physical properties and exhibits special activities in many reactions.
    This compound is solid at room temperature, with good stability and easy storage and operation. Looking at its appearance, it is mostly white to light yellow crystalline powder. This property makes it easy to disperse in many reaction systems and can effectively participate in the reaction process.
    2-% methoxypyridine boron has a high melting point, about [specific melting point value]. This property determines that it can remain stable in higher temperature environments and is not easy to decompose due to heat, which provides great convenience for reactions involving high temperature conditions.
    Its solubility is also a key physical property. It can be moderately dissolved in common organic solvents such as ethanol and dichloromethane, but it is difficult to dissolve in water. This solubility characteristic provides a specific range for the solvent selection of organic synthesis reactions, so that the reaction can be carried out smoothly in a suitable liquid phase environment, thereby optimizing the reaction conditions and improving the reaction efficiency and yield.
    Furthermore, the density of 2-% methoxypyridine boron is about [specific density value]. Although this physical parameter is often ignored in basic research, it has important reference value for material measurement and reaction system ratio in actual industrial production, and is related to the accuracy and stability of the entire production process. Overall, the physical properties of 2% methoxypyridine boron provide a solid foundation for its application in the field of organic synthetic chemistry. Chemists have carefully designed various reactions based on these properties to achieve efficient synthesis and preparation of complex organic compounds.
    What should be paid attention to when storing and transporting 2-methoxyiodobenzene?
    When storing and transporting 2-% methoxypyridyl boron, many key points need to be paid attention to. Its nature is delicate, and it is easy to contact with water and cause qualitative changes. Therefore, the storage place must be very dry, and there should be no water vapor intrusion at all. And it should be placed in a cool place, away from the source of heat. Due to high temperature, its stability can easily collapse, creating many hidden dangers.
    When transporting, the packaging must be strong and well sealed. It is packed in a special container to ensure that it is tight and seamless, and there is no opportunity for air and water vapor. The escort must be well aware of the characteristics of this object and can properly deal with it in case of emergencies.
    Furthermore, 2-% methoxypyridyl boron is prone to react with many substances. When storing and transporting, it must not be co-located with oxidizing agents, acids, etc., otherwise, it may cause a violent reaction and cause great harm. On its packaging, the warning label should be clear and prominent, so that contacts can identify its potential danger at a glance and treat it with caution.
    The handling process should not be hasty, and it should be handled with care to avoid collisions and falls, in case the packaging is damaged and causes leakage. If a leak occurs unfortunately, it should be acted immediately according to the established emergency strategy, evacuate the surrounding crowd, quickly clean up by professional personnel, and properly collect the residue. It must not be allowed to disperse, so as not to pollute the environment and endanger the safety of everyone.
    What is the market price of 2-methoxyiodobenzene?
    At present, the price of 2-methoxypyridine in the market often fluctuates due to the purity of the product and the situation of supply and demand.
    If its purity is higher, it is mostly used in fine chemical and pharmaceutical research and development. It is used in the pharmaceutical industry. It is a key intermediate for synthesis and can make special drugs. Its quality is high and its price is high. Such high-purity products in the city can cost hundreds of gold per kilogram, or even more than a thousand gold. It is difficult to prepare and requires extremely high precision control technology.
    As for the less pure ones, they are used in general chemical production, such as the production of certain pesticides and fragrances. This kind of product is slightly easier to prepare because its purity requirements are not as severe as those of pharmaceuticals, and its price is between tens of gold and hundreds of gold per kilogram.
    In addition, the situation of supply and demand also affects its price. If there is a pharmaceutical research and development boom, the demand for 2-methoxypyridine will increase greatly, and the supply will not meet the demand, the price will rise. On the contrary, if the market is saturated, the supply will exceed the demand, and the price will fall.
    And the cost of origin and transportation also affects the price. If it is shipped from a long distance, the price will be higher than that of the nearest producer. Therefore, in order to know the exact market price of 2-methoxypyridine, the actual price can only be obtained by carefully studying various factors and studying the market conditions at the time.