2 Nitro Iodo Benzene
Iodobenzene

2-Nitro Iodo Benzene

Fengxi Chemical

Specifications

HS Code

549656

Chemical Formula C6H4INO2
Molar Mass 249.005 g/mol
Appearance Yellow solid
Melting Point 55 - 59 °C
Boiling Point 281.8 °C at 760 mmHg
Density 1.992 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
Odor Pungent
Stability Stable under normal conditions but may react with strong oxidizing agents

As an accredited 2-Nitro Iodo Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 200g of 2 - nitro Iodo Benzene packaged in a sealed, corrosion - resistant container.
Storage 2 - nitro - iodo - benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents as it may be reactive. Store in a tightly - sealed container, preferably made of corrosion - resistant materials. Avoid storage near incompatible substances to prevent potential chemical reactions and ensure safety. Label the storage clearly for easy identification.
Shipping 2 - nitro Iodo Benzene is a chemical requiring careful shipping. It should be packaged in well - sealed, corrosion - resistant containers. Shipment must comply with hazardous material regulations, ensuring proper labeling and safe transport to prevent leakage and risks.
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2-Nitro Iodo Benzene
General Information
Historical Development
In the long river of time in China, the exploration process of chemical substances has also been ups and downs. The birth and evolution of this compound 2 - Nitro Iodo Benzene is quite meaningful.
In the past, all kinds of sages worked hard in the field of chemistry. At the beginning, due to the limitations of cognition and skills, the exploration of complex compounds was difficult. However, everyone was determined, and after countless attempts and pondering, they gradually touched the mystery of 2 - Nitro Iodo Benzene.
With the passage of time, the improvement of equipment, the improvement of knowledge, and the deepening of its cognition. From the initial observation of its properties to the clarification of its synthesis method, every step has been the work of the ancestors. The development of this compound is a testament to the unremitting efforts of chemists of all ages, and it also lays the foundation for future generations to continue to explore the chemical world.
Product Overview
2 - Description of Nitro Iodo Benzene
2 - Nitro Iodo Benzene is a special substance in the product. Its shape and color are often crystalline, color or light, and the outer surface is uniform. Its fabrication is exquisite, above benzene, the nitro-iodine atoms are in various positions, and they are mutually controlled, which makes them unique.
Its properties, chemical activity, nitro-absorptive properties, and the inverse orientation of iodine atoms play an important role in the reaction of polymorphism. In the field of synthesis, it is often important, can be standardized, and derived from compounds with many values.
It can only be obtained by precise control of the process, or the beginning of benzene, nitrification, chemical reduction, etc. However, the step-by-step operation is careful, because of the ease of reaction and the level of efficiency. Therefore, 2 - Nitro Iodo Benzene is very important in chemical research and production. Those who need to explore it in depth will develop their greater capabilities.
Physical & Chemical Properties
There is a thing today, named 2 - Nitro Iodo Benzene. Its properties are also related to physical and chemical characteristics. The color of this thing, or in the shape of light yellow, looks slightly transparent. At room temperature, it is usually solid and solid to the touch. Its melting degree is relatively fixed after testing, and it melts when heated and turns into a liquid state. As for the boiling point, it is also an inherent sign. When it reaches a specific heat, it gasifies into steam.
Its chemical properties are also meaningful. It has nitro and iodine atoms, so it shows unique properties in many reactions. Nitro is very active and can cause changes in nucleophilic substitution; iodine atoms are not idle and can cause many chemical changes. Looking at its structure, the benzene ring is the group, and the nitro group and iodine atoms are attached to it. With this structure, its physical and chemical properties are determined, which makes it useful in the field of chemical industry and medicine. In fact, it is also important for scientific research and industry.
Technical Specifications & Labeling
2-Nitro Iodo Benzene is a chemical substance. Its technical specifications and labeling (product parameters) are related to its quality, use and safety.
The preparation of this product requires a specific method. The reaction conditions must be precisely controlled, such as temperature, pressure and the ratio of the reactant. The raw materials used must be pure to prevent impurities from disturbing it.
On the label, state its name "2-Nitro Iodo Benzene", and specify its chemical formula and molecular weight. It should also indicate its physical and chemical properties, such as color, taste, state, melting point and solubility. Safety labels are indispensable to warn its hazards. If it is toxic, flammable, etc., it is necessary to inform people of protection. The product parameters list the purity, impurity content, etc. in detail to prove that it meets the standard. In this way, the standardization and safety of its preparation and use can be guaranteed.
Preparation Method
The method of making 2-Nitro Iodo Benzene is related to the raw materials and production process, reaction steps and catalytic mechanism. First take benzene as the starting material, and mix nitrate with sulfur and acid to obtain nitrobenzene. This step requires temperature control to avoid side reactions. Then, nitrobenzene reacts with iodine under the action of a catalyst. Commonly used catalysts can be copper salts and the like. During the reaction, pay attention to the ratio of materials. The amount of iodine is appropriate. If there is more, it will be expensive and heterogeneous, and if there is less, the yield will be low. The reaction conditions are appropriate for moderate temperature and pressure. If it is too high or too low, it will be unfavorable. After each step of the reaction, the impurities will be removed by separation and purification to obtain a pure product. In this process, 2-Nitro Iodo Benzene can be efficiently prepared
Chemical Reactions & Modifications
In recent years, the study of chemical things, in 2 - Nitro Iodo Benzene, has taken a lot of effort. Its transformation is wonderful, like the stars hidden in the night sky, waiting for our generation to explore it with wisdom.
At the beginning, it was implemented according to the usual method, and the effect of the transformation response did not meet expectations. Although its quality has potential, there are obstacles to the transformation, just like a boat against the current, it is difficult to move forward. Then think about the method of change, and study carefully where the agent is selected and the temperature is controlled.
Change to a new type of catalyst, and the temperature is precisely controlled. It is like clearing the clouds and seeing the sun, and the transformation should gradually improve. 2 - Nitro Iodo Benzene Under the new environment, the speed should be faster and the yield should also rise. Looking at its changes, it is like a phoenix bathing in fire and rejuvenating.
This change was not achieved overnight, but after several trials and errors, it was made over and over again. From this, I realized that chemistry needs to be constant and sensitive to change in order to gain insight into the mystery of transformation, optimize physical properties, and achieve the best.
Synonyms & Product Names
2 - Nitro Iodo Benzene is the same product name as Nitro Iodo Benzene
2 - Nitro Iodo Benzene, also known as nitroiodobenzene. Its same product also has 1-iodine-3-nitrobenzene and other factors. In the chemical industry, different companies or due to factors such as industry, market conditions, etc., the name of this chemical product is slightly different. However, it refers to this specific chemical product. Its product names may be different on the market. Some companies are named after their own brands, but they are based on their core ingredient 2 - Nitro Iodo Benzene. This compound plays an important role in the research direction of synthetic synthesis, etc., because of its special characteristics, it can be used for multiple reactions and assist in the synthesis and research of new substances. Therefore, the clarity of its trade name is essential for chemical research and related research.
Safety & Operational Standards
2 - Nitro Iodo Benzene is a chemical substance. It is essential for its safety and operating practices. It should not be ignored.
This substance is dangerous. For storage, it must be placed in a cool, dry and well-ventilated place. Keep away from fire, heat sources, and direct sunlight. Due to its nature or reaction with other substances, it should be stored separately from oxidizing agents, reducing agents, and alkalis. Do not mix storage. The storage place should be equipped with suitable materials to contain leaks.
During operation, operators must undergo special training and strictly follow the operating procedures. It is recommended that operators wear self-priming filter dust masks, chemical safety glasses, anti-poison infiltration work clothes, and rubber gloves. Avoid generating dust and avoid contact with oxidants, reducing agents, and alkalis. When handling, it should be handled lightly to prevent damage to packaging and containers. Equipped with leakage emergency treatment equipment.
If a leak unfortunately occurs, isolate the leakage contaminated area and restrict access. It is recommended that emergency personnel wear dust masks (full masks) and gas suits. Avoid dust, sweep it up carefully, and transfer it in a bag to a safe place. If a large amount of leakage occurs, collect it for recycling or transport it to a waste treatment site for disposal.
When using this substance for experiments or production, the experimental site should have good ventilation conditions, preferably in a fume hood. Before and after the experiment, carefully check the sealing of the equipment to prevent leakage. After use, the remaining 2-Nitro Iodo Benzene should be properly disposed of and not discarded at will. In this way, the safety of the operation process can be ensured and accidents can be avoided.
Application Area
2 - Nitro Iodo Benzene is an organic compound with a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate. Through delicate chemical reactions, it can be converted into compounds with specific pharmacological activities, or participate in the synthesis of antibacterial and antiviral drugs, contributing to the cause of human health.
In the field of materials science, this compound also has outstanding performance. Its unique chemical structure makes it possible to participate in the preparation of high-performance materials. For example, after polymerization, it is integrated into polymer materials, giving materials such as excellent optical properties or special electrical properties, which can help the research and development of new optoelectronic devices.
Furthermore, in the field of fine chemicals, 2-Nitro Iodo Benzene is often used to synthesize high-value-added fine chemicals, such as high-end pigments, special fragrances, etc., to meet the stringent needs of fine chemicals in different industries.
Research & Development
I am committed to the research and development of 2-Nitro Iodo Benzene. At the beginning, we explored the method of its synthesis, traversed various paths, and obtained the delicate method after repeated experiments. With specific reagents, control suitable conditions, so that the reaction goes forward.
Study its properties, check its stability and reactivity. This substance exhibits a unique chemical behavior under specific environments, paving the way for subsequent applications.
As for the development, look forward to its potential in the fields of medicine, materials, etc. Or it can be used as a key intermediate to make special drugs, or add novelty to materials. We should study it relentlessly, explore more possibilities, and promote it from the laboratory to practical use, contributing to the advancement of science and the prosperity of society.
Toxicity Research
There is a chemical substance today, named 2 - Nitro Iodo Benzene, and the study of its toxicity is quite important. Yu et al. studied this matter in detail to investigate the properties of this substance. Observe its structure and think about its biochemical effects. This substance may enter the human body, causing chaos to the internal organs and harming the luck of qi and blood. After various experiments, it has been found that it invades cells, can damage its vitality, and disrupt the order of its metabolism. Although it may be useful, its toxicity cannot be ignored. We must carefully investigate the methods of prevention, and know the way it enters the body, such as breathing and contact, all need to be observed. Design strategies to control it, so as to ensure the well-being of everyone, and do not make this poison a disaster to the world. Only then can it be used in the chemical industry, and it can be stable and far-reaching, harmless to living beings.
Future Prospects
There is a thing today, named "2 - Nitro Iodo Benzene", a chemist of our generation, and I have been studying it for years. Observe its properties, explore its quality, hope to be able to clarify its use, and expand its path.
The future prospect is when the new field is developed. First, in the field of medicine, this compound may be used to find new ways to cure diseases and save people. Its unique structure may be in line with the biochemical path of the human body, making special drugs and relieving the suffering of patients.
Second, the field of materials can also be used. With its characteristics, it may be able to refine new materials, with excellent insulation and strong properties, and shine in the electronics, construction and other industries.
We should do our best to explore its endless potential, looking forward to the future, and contribute to the progress of the world.
Where to Buy 2-Nitro Iodo Benzene in China?
As a trusted 2-Nitro Iodo Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Nitro Iodo Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-nitro Iodo Benzene?
2-Nitro + Iodo + Benzene is 2-nitroiodobenzene, which has a wide range of uses.
One of them is a key intermediate in the field of organic synthesis. Because of the nitro and iodine atoms attached to the benzene ring, both of them have active chemical properties. Nitro can be reduced to amino groups, thus providing the possibility to prepare compounds such as 2-aminoiodobenzene, while 2-aminoiodobenzene can be used as a key structural fragment in drug synthesis to construct molecules with specific pharmacological activities. Iodine atoms exhibit unique activities in many reactions, such as the Ullmann reaction, which can be coupled with compounds containing active hydrogen to form carbon-carbon bonds or carbon-heteroatomic bonds, which can assist in the synthesis of complex organic molecules.
Second, it also has applications in the field of materials science. With its chemical activity, it can participate in the preparation of functional polymer materials. For example, by polymerizing with specific monomers, the structure of 2-nitroiodobenzene is introduced into the polymer chain, endowing the material with unique electrical, optical or thermal properties, laying the foundation for the development of new optoelectronic materials.
Furthermore, in the process of drug development, 2-nitroiodobenzene can be used to build a diverse library of compounds. Scientists can use it as a starting material and modify it through a series of chemical reactions to synthesize many compounds with similar structures but different biological activities, and then screen lead compounds with potential medicinal value, providing rich materials for the creation of new drugs.
What are the physical properties of 2-nitro Iodo Benzene?
2-Nitroiodobenzene is an organic compound. It has various physical properties, which are detailed by you today.
Looking at its properties, at room temperature, 2-nitroiodobenzene is in a light yellow crystalline shape, which can be seen by the naked eye. Its melting point is quite important, about 38 to 41 degrees Celsius. The melting point is also the critical temperature at which a substance changes from a solid state to a liquid state. In this temperature range, the state of 2-nitroiodobenzene will change.
As for the boiling point, this is also the key physical property. The boiling point of 2-nitroiodobenzene is about 281 degrees Celsius. At boiling point, the temperature at which the saturated vapor pressure of the liquid is equal to the external atmospheric pressure. At this temperature, the liquid will vaporize violently.
In terms of solubility, 2-nitroiodobenzene is insoluble in water. Water is a common solvent, while 2-nitroiodobenzene has little solubility in it, due to the difference in the force between the two molecules. However, it is soluble in organic solvents such as ethanol, ether, and benzene. Ethanol, ether, and benzene are all organic solvents. They have similar molecular structures to 2-nitroiodobenzene. According to the principle of "similar miscibility", they are soluble.
Density is also one of its physical properties. The density of 2-nitroiodobenzene is relatively high, and the specific value is about 2.079g/cm ³. The density is the mass of the substance per unit volume. This value indicates that 2-nitroiodobenzene is heavier than the same volume of water and other substances.
In addition, 2-nitroiodobenzene has a certain degree of volatility, but its volatility is not very strong. Volatility is related to the ability of a substance to change from a liquid or solid state to a gaseous state. This property is also affected by factors such as its intermolecular force and boiling point.
From the above, it can be seen that the physical properties of 2-nitroiodobenzene are unique. In the field of organic synthesis and other fields, these properties have a great impact on its application and related operations, which cannot be ignored.
What is the chemistry of 2-nitro Iodo Benzene?
2-Nitro + Iodo + Benzene, or 2-nitroiodobenzene, has unique chemical properties and multiple reaction characteristics, which are related to many levels of organic synthesis.
As far as nucleophilic substitution is concerned, due to the strong electron-absorbing effect of the nitro group on the benzene ring, its o-para-position electron cloud density is significantly reduced, and the activity of iodine atoms is enhanced, which is vulnerable to attack by nucleophilic reagents. If sodium alcohol is used as the nucleophilic reagent, under appropriate conditions, the alkoxy group can replace the iodine atom to form 2-nitrophenyl ether compounds. This reaction mechanism is that the nucleophilic reagent first adds the benzene ring, and then the iodine ion of the leaving group The nitro group in 2-nitroiodobenzene also has typical reactivity. Under the action of reducing agent such as iron and hydrochloric acid system, the nitro group can be reduced to amino group to obtain 2-aminoiodobenzene. The reaction undergoes multiple electron transfer steps, and the nitro group is gradually converted into an amino group. This 2-aminoiodobenzene is an important organic synthesis intermediate, which can further participate in diazotization reactions, etc., to realize the conversion of various functional groups.
Its iodine atom can also participate in the coupling reaction catalyzed by metals. Under the catalysis of palladium, it is coupled with boric acid containing alkenyl groups and aryl groups to form carbon-carbon bonds. In this process, the palladium catalyst is first oxidized with the iodine atom, then metallized with another coupling agent, and finally reduced and eliminated to form a new carbon-carbon bond, providing a powerful means for the construction of complex organic molecular structures.
In addition, although the benzene ring of 2-nitroiodobenzene affects the electron cloud distribution due to nitro and iodine atoms, electrophilic substitution reactions can still occur. However, due to the localization effect of nitro and iodine atoms, the reaction check point is different from that of ordinary benzene, and the newly introduced groups mostly enter the meta-site. In conclusion, 2-nitroiodobenzene is rich in chemical properties and has a wide range of uses in the field of organic synthesis. It lays the foundation for the creation of new organic compounds. Through clever design of reaction conditions and reagents, a variety of target products can be synthesized.
What are the synthesis methods of 2-nitro Iodo Benzene
To make 2-nitroiodobenzene, there are two common methods. First, benzene is used as the starting material, and nitrobenzene is first obtained by nitrification. This step requires sulfuric acid and nitric acid to work together as reagents, and heating is required to introduce the benzene ring into the nitro group. Nitrobenzene is then halogenated, with iodine as the halogenating agent and the help of a catalyst to obtain 2-nitroiodobenzene. Although this approach can be successful, the reaction conditions are harsh, and the selectivity during halogenation is poor, and there are many by-products.
Second, aniline is used as the starting material. Aniline is first acetylated to protect the amino group and prevent it from overacting in the subsequent reaction. After nitrification of acetaniline, p-nitroacetaniline can be obtained. This step has excellent selectivity and mainly results in the P-nitroacetaniline is rehydrolyzed to restore the amino group, resulting in p-nitroaniline. P-nitroaniline reacts with sodium nitrite, hydroiodic acid and other reagents, and is converted into 2-nitroiodobenzene through diazotization, iodine substitution and other series of conversions. This diameter step is slightly more complicated, but each step has good reaction controllability and product purity or higher. The specific selection method depends on actual demand, availability of raw materials and cost considerations.
What are the precautions for 2-nitro Iodo Benzene in storage and transportation?
2-Nitroiodobenzene is a chemical substance, and many matters must be paid attention to when storing and transporting.
First, storage, this material is dangerous, and it must be placed in a cool, dry and well-ventilated place. Because of its sensitivity to heat, it is easy to decompose and cause danger when heated, so it should be avoided in high temperature places, away from fire and heat sources. And it should be stored in isolation from oxidizing agents, reducing agents, alkalis, etc., because of its mixing with it, it is easy to cause chemical reactions and cause accidents. In addition, the storage place should be equipped with suitable materials to contain leaks, in case of leakage, and can be dealt with in time.
As for transportation, practitioners must have professional training and be familiar with transportation specifications and emergency response methods. During transportation, the packaging must be firm to ensure that it will not be damaged and leaked during the bumps in the road. Transportation vehicles should also be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. During driving, it should be protected from exposure to the sun, rain and high temperature. Do not mix with contraindications, drive according to the specified route, and do not stay in densely populated areas and busy cities for a long time.
All of these are for the storage and transportation of 2-nitroiodobenzene, so as to ensure the safety of personnel and the environment.