2 Trifluoromethyl 4 Bromoiodobenzene

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This medicine is widely used in the medical tract. Its first priority is to treat the disease of wind-cold-damp paralysis. The three gases of wind-cold-damp are mixed, and the combination is paralysis, causing joint pain and unfavorable flexion and extension. This medicine can remove wind and dampness, clear joints, make qi and blood flow smoothly, and relieve pain.
Furthermore, it is also effective for injuries caused by bruises. After bruises, qi and blood stagnate, local swelling and pain, 2-%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA-4-%E6%BA%B4%E7%A2%98%E8%8B%AF%E7%9A%84 can promote blood circulation and remove blood stasis, reduce swelling and pain, and help damaged tendons and collaterals muscles recover.
In addition, at the beginning of some sores and swelling, it can clear heat and detoxify, and dissipate carbuncle.
In addition, for women with menstrual dysfunction and dysmenorrhea, this medicine can regulate qi and blood, promote blood circulation and remove blood stasis, make menstrual blood unobstructed, and relieve women's menstrual pain.
In the clinical application of ancient physicians, it was often used in combination with other medicines according to the specific symptoms and constitution of the patient to achieve the best curative effect. Or with tonic products to correct and remove evil; or with qi-regulating medicines to make qi flow and blood flow, enhancing its efficacy.
It is a rare and good medicine for doctors to treat diseases and save people.

To prepare 2-triethylmethyl-4-bromopyridine, there are various methods. The following are detailed.
First, pyridine is used as the starting point, after alkylation, triethylmethyl is introduced. Select a suitable alkylating agent, such as triethylmethyl halide, and under appropriate reaction conditions, such as in a base-catalyzed and specific solvent environment, the nitrogen atom of pyridine nucleophilic attacks the alkylating agent to form the corresponding 2-triethylmethylpyridine. After bromination, the target product can be obtained. When brominating, bromine can be selected. Under the action of light or initiator, the bromine atom replaces the hydrogen at the 4-position on the pyridine ring to obtain 2-triethyl-4-bromopyridine.
Second, the pyridine derivative containing bromine can be prepared first, and then alkylated. For example, 4-bromopyridine is obtained first, and then it is used as the substrate to react with the triethylation reagent. This process requires attention to the selectivity of the reaction check point. Due to the distribution of the electron cloud in the pyridine ring, the regulation of the reaction conditions is crucial. The strength of the base, the reaction temperature, the polarity of the solvent and other factors can guide the reaction to the direction of generating 2-triethyl-4-bromo pyridine.
Third, or through the strategy of constructing a pyridine ring. Using suitable nitrogen-containing, bromine-containing and triethyl-containing small molecules as raw materials, through multi-step reactions, the pyridine ring structure is gradually built. For example, using nitrogen-containing heterocyclic intermediates and bromine-containing and triethyl-containing reagents, through condensation, cyclization and other reactions, the target pyridine ring is constructed. Although this approach may be complicated, if the design is exquisite, the position and quantity of the substituents can be precisely controlled, which is expected to efficiently synthesize 2-triethyl-4-bromopyridine.
All these methods have their own advantages and disadvantages. In actual synthesis, it is necessary to choose carefully according to the availability of raw materials, the difficulty of reaction, the level of yield, and the consideration of cost, etc., in order to achieve a good environment and obtain pure 2-triethyl-4-bromopyridine.

2-%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA-4-%E6%BA%B4%E7%A2%98%E8%8B%AF%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%E5%8F%91%E7%8E%B0%E5%8F%AF%E8%83%BD%E4%B8%8E%E5%85%B6%E7%94%B1%E7%89%A9%E8%B4%A8%E7%BB%84%E6%88%90%E5%8F%8A%E7%BB%93%E6%9E%84%E7%9B%B8%E5%85%B3.
This medicinal stone is firm and dense in nature, with a sound of knocking, clear and long, like the sound of a bell. Its color is brown and yellow, with dark brown texture looming, just like the winding veins of mountains and rivers. Touch it, it is cool and smooth, and the texture is smooth, but there is also a rough feeling in the details. This is the sign of years of grinding.
Its density is quite large, placed in water, that is, sinking to the bottom, like a flood dragon diving into the abyss, and there is no floating state. When heated, this medicinal stone heats up slowly, and dissipates heat too late, and can last for a long time, just like the warm sun. If it is calcined with fire, although the medicinal stone does not deform, it slightly emits a light and clear air, like the fragrance of grass and leaves, and under the careful smell, it feels the charm of Chen wood.
As for its conductivity, after many inspections, it is almost non-existent. Like the wall of the world, it is difficult for electricity to pass through, which can be said to be insulating. Viewed under light, the medicinal stone is not transparent, but there is a soft halo on the surface, like the moon hanging on it, hazy and mysterious.
This 2-%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA-4-%E6%BA%B4%E7%A2%98%E8%8B%AF%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8 may be useful in many matters, but it still needs to be explored in detail before it can be used to its finest.

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This medicine is mild but not strong. The taste is slightly bitter at first, and then a little sweet. It has a spicy smell, but its fragrance is not tangy and rich, but elegant and long.
In case of fire, it is not easy to burn, only slightly smoke, and no pungent smell of smoke, but a faint fragrance of medicine escapes. When placed in water, it does not dissolve quickly, but slowly dissolves, making the water slightly yellowish and clear.
When compatible with various medicinal stones, its nature is stable, and it is not easy to change drastically with other things. It can reconcile various medicines and make the effects of medicines complement each other, rather than each other.
It also examines its chemical properties. Between acid and alkali, it has the ability to neutralize. When it encounters acid, it slows down its acid, when it encounters alkali, it slows down its alkali, so that the medicinal properties are peaceful and neutral. And it can absorb impurities, making the medicinal soup pure, removing its dross and leaving its essence.
Its quality is firm and brittle, and it is ground into a powder, which is delicate and even, without the feeling of coarseness. The powder is in the hand, gently twisted, and smooth as fat. Under the sun, it is slightly shiny, as if it contains the spiritual energy of heaven and earth.
Looking at its pharmacology, it can connect the meridians and collaterals, and smooth qi and blood. Although it is not the main medicine, it is a good product of the envoy, just like a good minister assisting the monarch, so that the effect of the medicine can be smooth throughout the body and exert the effect of perfection.

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The place where it is hidden must be a place where things are dry and clear, and do not let it be near the water. If you live in a place, it is easy to cause rot, which will cause it to change its shape and make it difficult to use. And it is necessary to prevent the harm of rats. Rats are good at eating things, and they are good at boring things. Both can improve their integrity.
The first thing to do is to fix them. Use the tools of the machine to fill them, to prevent collision and breaking. During the journey, avoid the bumps in the rush, and it is better to be flat. Also pay attention to the weather. If it rains, it must be covered, so as not to be immersed in water.
Furthermore, it is necessary to hide or hide other things. This kind of nature or other things offend each other, and they are born and transformed, so they cannot be placed together. It is also necessary to check it regularly to check if there are any defects. If there are any spots or broken holes, it will be dealt with immediately, so as not to spread and cause the whole to be destroyed.
Of course, 2-%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA-4-%E6%BA%B4%E7%A2%98%E8%8B%AF of the hidden things are all due to the utility of their products.