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What is the chemical structure of (2r) -3-iodo-2- [ (2-methylpropan-2-yl) oxycarbonylamino] propanoic Acid
(2R) - 3 - iodine - 2 - [ (2 - methylpropyl - 2 - yl) oxycarbonylamino] propionic acid, the structure of this compound is as follows:
First say "propionic acid", this is the main chain structure, containing three carbon atoms of carboxylic acid, carboxyl (-COOH) is located at one end of the main chain, this is the basic framework.
" (2R) ", this is the configuration label of chiral carbon. On the second carbon atom of the propionic acid main chain, it has chirality due to the different spatial arrangement of the four groups connected. This label indicates that the configuration of the chiral carbon is R-type, which determines one of the important characteristics of the spatial three-dimensional structure of the molecule.
"3-iodine" means that there is an iodine atom (-I) connected to the third carbon atom of the propionic acid main chain. The introduction of this halogen atom endows the molecule with specific chemical activity and reaction characteristics.
"2- [ (2-methylpropane-2-yl) oxycarbonylamino]", further analysis, "oxycarbonylamino" is the - NHCOO - structure, which is connected to the second carbon atom of the propionic acid backbone at one end, and " (2-methylpropane-2-yl) " at the other end. " (2-methylpropane-2-yl) " is also known as tert-butyl, and its structure is -C (CH 🥰). In this way, the whole constitutes the complex and unique chemical structure of the compound, and the interaction of each part determines its physicochemical properties and chemical reactivity.
What is the main use of (2r) -3-iodo-2- [ (2-methylpropan-2-yl) oxycarbonylamino] propanoic Acid
(2R) -3 -iodine-2 - [ (2-methylpropyl-2-yl) oxycarbonyamino] propionic acid, an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
In the process of organic synthesis, many complex and delicate compounds rely on this as the starting material to build the required structure through various chemical reactions. Its unique structural characteristics enable it to precisely guide the reaction direction in specific reactions and help synthesize the expected target product.
In the field of pharmaceutical research and development, this compound is also of great value. In the synthesis process of many drugs, it may participate in key steps to lay the foundation for the creation of drug molecules with specific pharmacological activities. Or because its structure is compatible with some activity checking points in the organism, it is expected to develop new drugs with excellent efficacy after reasonable modification and transformation.
Furthermore, in the field of materials science, it may be used as a raw material for the synthesis of functional materials. Through chemical reactions, it is introduced into the material structure to endow the material with unique properties, such as special optical, electrical or mechanical properties, opening up new paths for the development of materials science.
From this perspective, (2R) -3-iodine-2- [ (2-methylpropyl-2-yl) oxycarbonyamino] propionic acid is an organic compound, but it has played an indispensable role in many fields such as organic synthesis, pharmaceutical research and development, and materials science. It has promoted the continuous development of various fields and expanded the boundaries of human cognition and application.
What are the synthesis methods of (2r) -3-iodo-2- [ (2-methylpropan-2-yl) oxycarbonylamino] propanoic Acid
The method of synthesizing (2R) -3-iodo-2- [ (2-methylpropyl-2-yl) oxycarbonyl amino] propionic acid is very particular.
First, the corresponding amino acid can be started. First, the amino group is protected by tert-butoxycarbonyl (Boc), which is a commonly used method. Select a suitable tert-butoxycarbonylation reagent, such as di-tert-butyl dicarbonate (Boc 2O O), under mild reaction conditions, such as in a suitable solvent, such as dichloromethane, add an organic base such as triethylamine to promote the reaction of the amino group with Boc 2O O to form an amino acid derivative protected by Boc.
Then, iodide the carboxyl side. A specific halogenated reagent, such as N-iodosuccinimide (NIS), can be used, and an appropriate amount of initiator, such as azodiisobutyronitrile (AIBN), can be added under heating or lighting conditions to iodize the carboxyl ortho-carbon to obtain the target product.
Second, you can also start with the corresponding ester compound. First, the ester compound with the protective amino group is hydrolyzed under basic conditions to transform the ester group into a carboxyl group. Then, the same suitable halogenation method is used to achieve iodization with NIS and other reagents, and the final product is (2R) -3-iodo2- [ (2-methylpropyl-2-yl) oxycarbonylamino] propionic acid.
When operating, it is necessary to pay attention to the precise control of the reaction conditions. If the temperature is too high or too low, it may affect the rate and selectivity of the reaction. The choice of solvent is also crucial to ensure that it has good solubility to the reactants and reagents and does not interfere with the reaction process. During the reaction process, the progress of the reaction should also be monitored in real time, and means such as thin layer chromatography (TLC) should be used to ensure that the reaction proceeds in the expected direction to improve the purity and yield of the product.
What are the physical properties of (2r) -3-iodo-2- [ (2-methylpropan-2-yl) oxycarbonylamino] propanoic Acid
(2R) -3 -iodine-2 - [ (2-methylpropyl-2-yl) oxycarbonylamino] propionic acid, an organic compound. Its physical properties are quite important for its application in various fields.
First, the appearance is usually white to white solid powder. This form is easy to store and transport, and in many chemical reactions, the powdered substance can provide a large reaction surface area, which is conducive to the progress of the reaction.
The melting point is about a specific temperature range. The melting point is the inherent physical property of the substance. For the compound, accurate melting point determination can help to determine its purity. If impurities are mixed in, the melting point will often change, or decrease, or the melting range will become wider.
Solubility is also a key physical property. In organic solvents, such as common ethanol and dichloromethane, etc., it exhibits a certain solubility. This property makes it possible to choose a suitable solvent according to the reaction requirements in organic synthesis to achieve the dissolution, reaction and separation of compounds. In water, the solubility is relatively limited, because although there is a part in the structure of the compound that can form hydrogen bonds with water, the hydrophobicity of the overall structure also plays a role.
Density is also one of its physical properties. Although its specific value needs to be accurately determined experimentally, the density is of guiding significance for the operation of the solution preparation and separation process. Only by knowing the density can we know the fluctuation of the compound in different media and help the design of related processes.
In summary, the physical properties of (2R) -3-iodine-2- [ (2-methylpropyl-2-yl) oxycarbonyamino] propionic acid, such as appearance, melting point, solubility and density, play an indispensable role in its research, application and development of related processes.
What is the market outlook for (2r) -3-iodo-2- [ (2-methylpropan-2-yl) oxycarbonylamino] propanoic Acid?
(2R) -3 -iodine-2 - [ (2-methylpropyl-2-yl) oxycarbonylamino] propionic acid, this compound has great potential in the field of pharmaceutical and chemical industry, and the market prospect is promising.
Looking at its use in drug synthesis, this compound may be a key intermediate. Taking the development of anti-cancer drugs as an example, in the process of creating many innovative drugs, it is necessary to build a molecular framework with specific activities through its unique structure. Because its structure contains iodine atoms and specific carbamate groups, it can endow drugs with unique physical and chemical properties and biological activities, so the demand for drug chemical synthesis may increase day by day.
In the field of chemical production, with the vigorous development of the fine chemical industry, the demand for high value-added intermediates is increasing. This compound can be used to synthesize special materials or functional additives due to its special structure. With the technological innovation of the chemical industry, if its synthesis process can be optimized and the cost can be controlled, it will also gain a broad application space in the chemical market.
However, its market development also faces challenges. The synthesis process is complex, involving steps such as iodine substitution reaction and amino protection, which may lead to high production costs and limit large-scale production. And iodine resources are limited, and the price fluctuates, which affects the stability of its market supply.
But overall, with the advancement of science and technology, the optimization of the synthesis process can be expected, and the demand support of the pharmaceutical and chemical industries, (2R) - 3 - iodine - 2 - [ (2 - methylpropyl - 2 - yl) oxycarbonyamino] propionic acid has a bright future market prospect and is expected to emerge in more fields, contributing to the development of the industry.