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3, 3 ', what is 5-triiodo-l-thyronine?
3% 2C3% 27% 2C5 - triiodo - l - thyronine, or triiodothyronine, is the central body of human thyroid hormones. Its functions in the body are extremely complex and critical.
In terms of physiological effects, the first is to promote the rate of metabolism in the body. It can accelerate the oxidation process in cells, thereby increasing the basal metabolic rate, and increasing the body's oxygen consumption and calorie production. Just like adding firewood to a stove, the firepower is more intense, which makes the energy supply of life activities more abundant. In this process, the metabolism of sugar, fat and protein is regulated by it. In carbohydrate metabolism, it not only helps glycogen decomposition, but also accelerates the oxidation and utilization of glucose, just like providing assistance for the "burning" of sugar; in fat metabolism, it can not only promote fat decomposition, but also affect the synthesis and distribution of fat, just like the "dispatcher" of fat; in protein metabolism, it can promote synthesis at physiological doses and maintain the normal growth and development of the body. If the dose is inappropriate, it may cause increased protein decomposition.
In addition, it also plays a pivotal role in growth and development. In particular, it has a profound impact on the development of the nervous system and bones. In embryo and infancy, if this hormone is deficient in secretion and the development of the nervous system is blocked, it can cause mental retardation, slow response, slow bone growth, and short stature. This is the so-called stenosis. Like a building, the cornerstone is unstable, and the overall structure is difficult to form.
In addition, it also has the ability to regulate the excitability of the nervous system. The right amount of hormones can keep the nervous system alert and sensitive, making people think quickly and respond quickly. If the hormone level is abnormal, or the excitability is too high, there will be restlessness, insomnia, etc.; or the excitability is too low, showing a state of depression and drowsiness.
Triiodothyronine plays an irreplaceable role in the maintenance of human physiological balance and the promotion of growth and development. It is like a key gear in a delicate clock. Although it is small, it controls the overall operation.
What are the physiological functions of 3, 3 ', 5-triiodo-l-thyronine?
3,3 ', 5' -triiodol-L-thyronine is a key factor in human thyroid hormones and plays a crucial role in the regulation of physiological functions of the body. Its physiological functions are complex and critical, as detailed below:
First, it is related to the regulation of energy metabolism. This substance can significantly improve the basal metabolic rate and greatly increase the body's thermogenesis. It can induce the production of sodium-potassium-ATPase on the cell membrane. This enzyme is of great significance in maintaining the balance of ion concentrations inside and outside the cell. However, when it hydrolyzes ATP, it will release a lot of energy to convert into heat. At the same time, it also has a profound impact on the metabolism of sugar, fat and protein. In sugar metabolism, it not only promotes the absorption and utilization of sugar, but also accelerates glycogen decomposition, causing blood sugar to rise; in fat metabolism, it promotes lipolysis and oxidation, thereby supplying energy to the body; in protein metabolism, it can promote protein synthesis at physiological doses, and in excess, it will promote protein decomposition.
Second, it has a profound impact on growth and development. Especially in infants and young children, it is indispensable for the development of the nervous system and bones. If this hormone is deficient in infants and young children, it will lead to stunted mental development, short stature, and severe bone development.
Third, it is crucial for the role of the nervous system. It can improve the excitability of the nervous system, which not only affects the proliferation, differentiation and myelination of nerve cells, but also regulates the function of the differentiated and mature nervous system. When there is too much thyroid hormone, people are prone to symptoms such as restlessness and insomnia; when there is a lack of thyroid hormone, it is easy to appear as drowsiness and sluggishness.
Fourth, it also has many effects on the cardiovascular system. It can enhance the contractility of the heart, speed up the heart rate, and increase the output of the heart. It can up-regulate the number and affinity of β-adrenergic receptors on the membrane of cardiomyocytes, enhance the sensitivity of the heart to catecholamines, and then improve the pumping function of the heart.
What is the normal level of 3, 3 ', 5-triiodo-l-thyronine in the human body?
3% 2C3% 27% 2C5-triiodo-l-thyronine is triiodothyronine, referred to as T3. In the human body, its normal level will vary depending on the detection method and the detection population.
Usually the normal range of total serum T3 is 1.3-3.1 nmol/L. This is a common value range for adults, and the normal value of children, pregnant women and other people will fluctuate.
The normal range of free T3 is about 2.8-7.1 pmol/L. Free T3 can more accurately reflect the thyroid function status.
T3 secreted by the thyroid gland plays a key role in many physiological processes such as human metabolism, growth and development. If the T3 level deviates from the normal range, it may indicate abnormal thyroid function, such as T3 levels often increase in hyperthyroidism and decrease in hypothyroidism. In clinical diagnosis, in addition to T3 values, it is also necessary to comprehensively consider T4, TSH and other indicators, combined with patient symptoms and signs, to make an accurate diagnosis.
3,3 ', What diseases does 5-triiodo-l-thyronine deficiency cause?
If there is a deficiency of 3,3 ', 5' -triiodine-L-thyronine, it may cause various diseases. This is related to the subtle transportation of the human body, and it has vital functions in metabolism, growth and development, and many other functions.
If it is deficient, the first to bear the brunt may be a disease of hypothyroidism. Under this disease, the body's metabolism slows down, and it can be seen that it is afraid of cold. Even in a warm environment, people feel cold invading the body; lack of energy, and they feel tired after a little daily labor, making it difficult to continue to manage affairs; thinking is also tired, slow to respond, memory loss, and thinking and coping with everything is slow.
Furthermore, growth and development are also constrained. For children, it is particularly critical. Because this is the golden period of rapid physical growth and intellectual development, the lack of 3,3 ', 5-triiodol-L-thyronine can cause short stature, bone growth retardation, and height growth that does not reach normal standards; intellectual development may also be hindered, learning ability declines, and cognitive level is difficult to compare with peers, affecting their future long-term development.
During pregnancy, if a woman is deprived of this substance, the harm is even greater. Not only is her own health worried, it is easy to experience discomfort during pregnancy, and it has a huge impact on fetal development. Or cause fetal nervous system dysplasia, or mental retardation, motor development retardation and other problems after birth, which is related to their well-being in life.
It can be seen that although 3,3 ', 5-triiodol-L-thyronine is small, it has a profound impact on human health. When deprived, various diseases are plagued and cannot be ignored.
What are the effects of 3, 3 ', 5-triiodo-l-thyronine overdose?
If 3% 2C3% 27% 2C5 - triiodo - l - thyronine (triiodothyronine, referred to as T3) is excessive, the impact on human health is not limited to one end.
The first to bear the brunt is the appearance of hypermetabolism. T3 regulates the metabolic rate of the human body and is related to the weight of Qi. When overdose occurs, it is like the wheel of metabolism is running rapidly, causing the basal metabolic rate to rise sharply. Under this situation, the body's heat production surges, and people often feel hot and dry. Even in a cool place, they often sweat profusely. And the energy consumption is too fast, the diet has not changed, the weight is often declining, and the body is gradually losing weight.
The burden on the heart is also increased. Excessive T3 causes the excitement of the sympathetic nerves to increase greatly, and the heart seems to be receiving an expedited order, and the beating becomes more frequent and powerful. Over time, the heart rate continues to remain high, and the symptoms of heart palpitations are frequent. Patients often feel flustered and uneasy. In severe cases, it may cause arrhythmia, cardiac rhythm disorder, and even involve the heart's pumping function, endangering the safety of life.
Furthermore, the nervous system is also affected. People are often in an excited state, with violent mood swings, irritability and irritability, like a powder keg that is about to burn. Sleep at night is also disturbed, tossing and turning, and it is difficult to sleep. Over time, they are mentally depressed, and their memory is impaired, which is harmful to daily labor and study.
Musculoskeletal aspects are also difficult to escape. Patients often feel muscle weakness and fatigue, as if they are weighed down by a thousand catties. And the occasional muscle tremor, although slight tremor seems fine, is actually a warning to the body. In the bones, calcium loss accelerates, bone is gradually loose, and the risk of fracture is significantly increased.
Therefore, the balance of T3 is related to the overall situation of human health. Excessive state, many hazards, cannot be ignored.
