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3, 3 ', 5 - What is triiodothyronine?
3,3 ', 5-triiodothyronine is a crucial thyroid hormone in the human body. It plays a key role in the regulation of human metabolism, growth and development, and many physiological functions.
This hormone is secreted by the thyroid gland, and its synthesis and secretion are precisely regulated by the hypothalamic-pituitary-thyroid axis. The hypothalamus secretes thyroid-stimulating hormone-releasing hormone, which stimulates the pituitary to secrete thyroid-stimulating hormone, which in turn prompts the thyroid gland to synthesize and release 3,3', 5-triiodothyronine.
3,3 ', 5-triiodothyronine has a wide range of physiological effects. In terms of metabolism, it can improve the basal metabolic rate, speed up the body's heat production, and promote the metabolism of carbohydrates, fats and proteins. For example, in fat metabolism, it can accelerate the oxidative decomposition of fats and supply energy to the body. At the level of growth and development, it is particularly critical for the development of the nervous system and bones. If this hormone is not secreted enough in childhood, it can cause stunting, mental retardation, short stature, etc.
In addition, it also has an impact on the cardiovascular system, which can enhance the contractility of the heart, accelerate the heart rate, and increase the cardiac output. At the same time, it is also indispensable for maintaining the excitability of the nervous system. An appropriate amount of 3,3 ', 5-triiodothyronine can make people full of energy and quick thinking. If the secretion is abnormal, it can cause nervous system dysfunction.
Clinically, the detection of the level of 3,3 ', 5-triiodothyronine in the blood is an important basis for the diagnosis of thyroid diseases. When hyperthyroidism occurs, its level often increases; when hypothyroidism occurs, its level often decreases. Therefore, doctors can accurately diagnose the condition and give appropriate treatment according to its value and combined with the patient's symptoms and signs.
What is the effect of 3, 3 ', 5 - triiodothyronine?
3% 2C3% 27% 2C5 - triiodothyronine, or triiodothyronine, is an important component of thyroid hormones and plays a key role in the regulation of human physiology. Its functions are as follows:
First, it can promote metabolism. It can significantly improve the basal metabolic rate and speed up the oxidative decomposition process of many substances in the body, thereby increasing the body's heat production. For example, in cold winter, the human body will secrete more of this hormone to improve heat production and maintain body temperature.
Second, it has a profound impact on growth and development. Especially in infancy and young children, it is essential for nervous system and bone development. If this hormone is not secreted enough in infants and young children, it is very likely to lead to stupidity, mental retardation, short stature and other serious consequences.
Third, it can regulate the excitability of the nervous system. An appropriate amount of this hormone can maintain the normal excitability of the nervous system. When its secretion increases, people are prone to emotional agitation, insomnia, hyperhidrosis and other symptoms; reduced secretion may lead to mental weakness, drowsiness, etc.
Fourth, it also has an effect on the cardiovascular system. It can enhance cardiac contraction, speed up heart rate, and increase cardiac output. If secreted abnormally, it may cause cardiovascular dysfunction.
In short, 3% 2C3% 27% 2C5 - triiodothyronine plays an indispensable role in human growth, development, metabolism, and regulation of various system functions, and is of great significance to maintaining human health.
3, 3 ', 5 - What is the normal level of triiodothyronine?
3% 2C3% 27% 2C5 -triiodothyronine is one of the thyroid hormones, which plays a key role in human metabolism, growth and development and many other physiological processes. Its normal level will vary depending on the detection method and the difference of the detection population.
Generally speaking, the normal reference range of serum total triiodothyronine (TT
) is 1.3-3.1 nmol/L. The normal reference range of free triiodothyronine (FT
) is about 3.1-6.8 pmol/L. These values are for reference only. In actual diagnosis, it is necessary to combine the patient's symptoms, signs and other thyroid function indicators, such as thyroxine (T4), thyroid stimulating hormone (TSH), etc., to be determined comprehensively.
If the level of triiodothyronine is abnormal, or it indicates a problem with thyroid function. For example, if the level is increased, it is common in hyperthyroidism, and the patient may be accompanied by sweating, palpitations, weight loss, hand shaking and other symptoms; if the level is reduced, it is more common in hypothyroidism, and the patient may have fatigue, chills, lethargy, edema and other manifestations.
Because the human body's physiological state is complex and changeable, and the detection methods are also different, the exact normal level value should be subject to the reference range provided by the medical institution. When a doctor diagnoses a disease, he must carefully observe all factors and act cautiously to achieve accuracy.
3, 3 ', 5 - triiodothyronine abnormalities may indicate which diseases?
3,3 ', 5-triiodothyronine (T3) abnormality may indicate the following diseases:
First, thyroid self-disease. If T3 is elevated, the possibility of hyperthyroidism is quite large. This is caused by hyperfunction of the thyroid gland itself, synthesis and secretion of excessive thyroid hormones. Patients often suffer from palpitation, hypersweating, weight loss, hand shaking, etc., as if the body's yang qi is excessive, qi and blood run too fast. And if T3 is reduced, it may be hypothyroidism. At this time, the secretion of thyroid hormones is insufficient, the body's metabolism is slowed down, and chills, fatigue, drowsiness, edema, etc. often appear, just like yang qi deficiency, insufficient warming function.
Second, pituitary lesions. The pituitary gland is the upstream organ that regulates thyroid function. If there is a problem with the pituitary gland, such as a pituitary tumor, it will affect the secretion of thyroid stimulating hormone (TSH), which in turn affects the synthesis and release of thyroid hormones including T3. If TSH is abnormally increased or decreased, it will cause fluctuations in the level of T3. This is due to the disorder of the relationship between viscera and viscera.
Third, non-thyroid disease syndrome. In some serious diseases, such as serious infections, trauma, and malignant tumors, the body is under stress, thyroid hormone metabolism will change, and T3 levels can be reduced. This is a self-protection mechanism of the body, but it also reflects the severity of the disease, just like the human body's qi and blood operation and viscera functions are affected in distress.
How to detect the level of 3, 3 ', 5 - triiodothyronine?
In order to detect the level of 3,3 ', 5-triiodothyronine, although the ancient method is different from today, there are still traces to follow. In the past, physicians wanted to know the state of subtle substances in the body, often by observing the color according to the pulse and observing the shape of the syndrome. Looking at the face of a person, if you see flushing, hot and sweaty, or you can think of the hormone level or high; if you are pale, cold and cold, you may consider the level or low. According to its pulse, if the pulse number is strong, it may be related to the strong hormone; if the pulse is late and weak, it may be related to the decline of hormones.
In today's world, science and technology are prosperous, and the level of 3,3 ', 5-triiodothyronine is detected, thanks to advanced testing technology. The common method is to take a patient's blood sample. With modern instrument analysis, such as radioimmunoassay, it can accurately measure its content in the blood. This method uses the principle of competition and binding of radionuclide-labeled antigens and non-labeled antigens to specific antibodies. After a series of operations, the specific value can be known.
There is also chemiluminescence immunoassay, which is more sensitive, rapid and accurate. Based on the photon signal released by the chemical reaction, the level of 3,3', 5-triiodothyronine in the sample is accurately determined. Doctors can determine the level of this hormone in their bodies based on the data obtained from this test, combined with the patient's symptoms and signs, and then provide a solid basis for diagnosing diseases and formulating treatment methods.
