3 3 Diiodo L Thyronine
Iodobenzene

3 3 Diiodo L Thyronine

Fengxi Chemical

Specifications

HS Code

474232

Chemical Formula C15H12I2NO4
Molar Mass 523.07 g/mol
Appearance White to off - white powder
Solubility Slightly soluble in water, more soluble in organic solvents like ethanol
Purity Typically high - purity (e.g., 98% or above in commercial products)
Melting Point Approximately 220 - 225 °C
Optical Activity It is an L - isomer, so it has optical activity
Stability Stable under normal storage conditions, but sensitive to light and air
Role A metabolite in thyroid hormone metabolism
Odour Odourless
Chemical Formula C15H12I2NO4
Molar Mass 527.07 g/mol
Appearance White to off - white powder
Solubility In Water Poorly soluble
Melting Point Approximately 235 - 238 °C
Cas Number 659 - 34 - 7
Isomeric Form L - isomer
Role In Body A thyroid hormone metabolite
Stability Stable under normal storage conditions
Purity Typical Range Often 95%+ purity in commercial products
Chemical Formula C15H12I2NO4
Molecular Weight 521.07 g/mol
Appearance White to off - white powder
Solubility In Water Poorly soluble
Solubility In Organic Solvents Soluble in some organic solvents like DMSO
Pka Value Approximately 4.5 (carboxyl group)
Melting Point 180 - 185°C
Biological Role A metabolite in thyroid hormone metabolism
Isomeric Form L - isomer
Storage Condition Stored at -20°C in a dry environment
Chemical Formula C15H12I2NO4
Molecular Weight 499.07
Appearance Solid
Solubility In Water Poor
Solubility In Organic Solvents Moderate in some organic solvents like ethanol
Melting Point Approximately 200 - 210 °C
Pka Value Has acidic groups with characteristic pKa values related to carboxylic acid and phenolic - OH
Biological Activity Thyroid - hormone - like activity, affects metabolism
Stability Stable under normal storage conditions away from light and moisture
Color White to off - white
Packing & Storage
Packing 100g of 3,3'-diiodo-L-thyronine packaged in a sealed, airtight container.
Storage 3,3'-Diiodo-L-thyronine should be stored in a cool, dry place, away from direct sunlight and heat sources. Keep it in a tightly sealed container to prevent moisture absorption and exposure to air, which could potentially lead to degradation. Store it at a recommended temperature, typically around 2 - 8°C if refrigerated storage is indicated, to maintain its chemical integrity and stability over time.
Shipping 3,3'-Diiodo-L-thyronine is shipped in accordance with strict chemical transport regulations. It is carefully packaged to prevent breakage and leakage, often in air - tight containers, and transported via approved carriers to ensure safe delivery.
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3,3'-diiodo-l-thyronine 3,3'-diiodo-l-thyronine 3,3'-diiodo-l-thyronine
General Information
Frequently Asked Questions
What are the main uses of 3,3 '-diodol-l-thyronine?
3% 2C3% 27 -diiodo-l-thyronine is 3,3 '-diiodo-L-thyronine, which is used in medical pharmacology and has many wonderful uses.
Its primary use is related to the regulation of human metabolism. The human body is like a precision-operated instrument, and metabolism is its source of power, and 3,3' -diiodo-L-thyronine plays a key role here. It can act on many tissue cells, such as liver, muscle, etc., to accelerate the oxidative decomposition of intracellular substances, release energy, and supply it for the daily activities of the human body, just like adding power to the operation of the instrument. In this process, the metabolism of carbohydrates, fats and proteins is regulated by it to maintain balance and ensure the orderly operation of various functions of the human body.
Furthermore, it also has an important impact on growth and development. In early childhood, physical development is like a seedling that breaks the ground, and various substances and regulatory factors are urgently needed. 3,3 '-Diiodol-L-thyronine helps improve the nervous system, promotes the differentiation and maturation of brain cells, and enables the normal development of children's intelligence. At the same time, it is also indispensable for bone development. It can coordinate with other hormones to regulate the activities of osteoblasts and osteoclasts, and ensure the normal growth and remodeling of bones. It is like building a stable framework for the growth of seedlings.
In addition, in the cardiovascular system, 3,3 '-diiodine-L-thyronine also plays a role. It can regulate the contractile and diastolic functions of the heart, affecting heart rate and cardiac output. When appropriate, it can make the heart beat vigorously, blood circulation smooth, maintain the stability of the cardiovascular system, like dredging the river of circulation, to ensure the continuous flow of water.
However, if this material is out of balance, whether it is too much or too little, it will cause abnormalities in the body. Too much will cause hypermetabolism, sweating, weight loss, heart palpitations, etc.; too little will cause metabolic retardation, causing chills, fatigue, edema, etc. Therefore, 3,3 '-diiodine-L-thyronine is essential for maintaining human health and its use cannot be ignored.
What are the side effects of 3,3 '-diodol-l-thyronine?
3,3 '-Diiodol-L-thyronine has many side effects. The first to bear the brunt of human physiology, or cause metabolic disorders. If this substance is involved in the human body, it can cause sudden changes in the metabolic rate, causing diseases such as weight abnormalities. Or sudden weight loss, due to hypermetabolism, the body's consumption increases sharply; or the weight rises, the metabolism slows down, and fat accumulates.
Furthermore, it is also harmful to the cardiovascular system. It can make the heart beat faster and increase the load on the heart. For a long time, it is easy to induce heart palpitations, arrhythmias and other diseases, and even affect the heart function and damage the heart force.
The endocrine system is also disturbed by it. Interferes with the normal secretion rhythm of the thyroid gland, causes imbalance of thyroid hormones, feeds back to the pituitary gland and hypothalamus, disrupts the homeostasis of the entire endocrine axis, and causes many endocrine disorders, such as mood swings, menstrual disorders, etc.
In the nervous system, it often causes nervousness and anxiety, making it difficult for people to maintain a calm state of mind, sleep is also affected, and insomnia occurs. In the long run, it can cause mental weakness and endanger the health of the nervous system.
The digestive system is also unavoidable. Or cause abnormal appetite, or hyperactivity or decline, and gastrointestinal peristalsis, causing indigestion, diarrhea or constipation, etc., affecting nutrient absorption and waste excretion.
What are the applicable populations of 3,3 '-diodol-l-thyronine?
3% 2C3% 27 -diiodo-l-thyronine is 3,3 '-diiodol-L-thyronine, which is an important intermediate in the synthesis of thyroid hormones. Its applicable populations are as follows:
-hypothyroidism: Insufficient thyroid hormone secretion in this population, 3,3' -diiodol-L-thyronine can help regulate hormone levels in the body, relieve symptoms such as fatigue, chills, drowsiness, weight gain and other symptoms caused by hypothyroidism, and restore the body's metabolism to normal.
- Those with thyroid-related diseases and need to adjust hormone balance: for example, suffering from autoimmune thyroiditis, disease or thyroid hormone secretion disorder, appropriate supplementation of 3,3 '-diiodol-L-thyronine may assist in maintaining thyroid hormone balance and improve the condition.
- Some special groups, such as women during pregnancy or breastfeeding: During pregnancy, women have increased demand for thyroid hormones. If thyroid function is slightly insufficient, it may affect the intellectual and physical development of the fetus. Timely supplementation of 3,3' -diiodol-L-thyronine can protect the health of the mother and fetus.
However, supplementation of 3,3 '-diiodol-L-thyronine must be cautious and should be carried out under the guidance of a professional doctor. Due to improper dosage, it may cause hyperthyroidism symptoms such as palpitations, sweating, and insomnia, which can cause damage to health.
Does 3,3 '-diodol-l-thyronine interact with other drugs?
3% 2C3% 27 -diiodo-l-thyronine is 3,3 '-diiodo-L-thyronine, which is a key intermediate product in the biosynthesis of thyroid hormones. Whether this substance interacts with other drugs needs to be analyzed in detail from the general pharmacological properties and body reactions.
The interaction of husband drugs is often related to metabolism, transport, and target binding. 3,3' -diiodo-L-thyronine has a unique metabolic pathway in the body, or is catalyzed by a specific enzyme system. If other drugs affect the activity of this enzyme system, it is easy to initiate interactions. For example, some liver drug enzyme inducers can accelerate its metabolism, reduce blood drug concentration, and reduce drug efficacy; while enzyme inhibitors do the opposite, increase its concentration, or increase the risk of adverse reactions.
Furthermore, drug transport is also key. Transmembrane transport proteins on the cell membrane are responsible for their transmembrane transport. If other drugs compete with the transporter for binding check points, their distribution and efficacy will be affected.
As for target binding, 3,3 '-diiodol-L-thyronine acts on a specific receptor to exert physiological effects. If other drugs have affinity with the receptor, or interfere with its binding to the receptor, or change the receptor conformation, their efficacy can be affected.
Another important factor is the body's own state. If the patient has liver and kidney dysfunction and drug metabolism and excretion are blocked, the possibility of interaction is greatly increased when combined with other drugs.
Therefore, from a comprehensive perspective, 3,3 '-diiodine-L-thyronine is highly likely to interact with other drugs. When using clinical drugs, doctors must carefully observe the characteristics of the drug and the individual condition of the patient, and use prudent drugs to prevent adverse interactions and ensure the safety and effectiveness of the drug.
What are the precautions for the use of 3,3 '-diodol-l-thyronine?
3% 2C3% 27 - diiodo - l - thyronine is 3,3 '-diiodine-L-thyronine, which is commonly used by physicians for treating diseases. However, when using it, many matters must be observed.
The first to bear the brunt is the dose. If you use too little, it may be difficult to achieve the effect of treatment; if you use too much, it is easy to cause various adverse reactions, such as palpitations, tremors, sweating, insomnia, etc., all due to the excessive impact of the drug on human metabolism. Therefore, the doctor must carefully review the patient's condition, age, weight, etc., and accurately weigh to determine the appropriate dose.
Furthermore, the course of medication should not be ignored. It is necessary to determine a reasonable course of treatment according to the severity and severity of the disease and the recovery of the patient. If the course of treatment is too short, the disease may not be cured, and it is easy to cause the disease to repeat; if the course of treatment is too long, the body may become dependent on the drug, or cause other potential harm.
During the medication period, it is necessary to closely monitor the patient's physical condition. Observe the changes in their symptoms and regularly check the thyroid function and other related indicators in order to adjust the medication plan in time. If the patient experiences sudden discomfort during the medication, such as allergic reactions, itchy skin, erythema, etc., or other abnormal manifestations, stop the medication immediately and seek medical attention immediately.
In addition, when using 3,3 '-diiodine-L-thyronine in combination with other drugs, special caution is required. Or interact with certain drugs, causing changes in drug efficacy and increasing the risk of adverse reactions. Therefore, before taking medication, patients must inform the doctor in detail of other drugs they are using in order to weigh the pros and cons and ensure the safety of medication.
In short, although 3,3' -diiodine-L-thyronine is a good medicine for treating diseases, it can only be used cautiously by doctors and patients should follow the doctor's advice to achieve the best therapeutic effect and avoid its harm to the greatest extent.