3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-alanine

3 - [4- (4-hydroxy-3,5-diiodophenoxy) -3,5-diiodophenyl] -alanine, this is an organic compound. Looking at its name, its chemical structure can be gradually deduced according to the nomenclature of organic chemistry.
"Alanine" is the basic skeleton of the compound. Alanine is one of the amino acids, with amino (-NH ²) and carboxyl (-COOH) groups, and the two are connected to the same carbon atom. This carbon atom is connected to another methyl (-CH ²) and hydrogen atom.
"3- [4- (4-hydroxy-3,5-diiodophenoxy) -3,5-diiodophenyl]" is a substituent attached to the alanine alpha-carbon atom. This substituent contains two phenyl ring structures.
One benzene ring is connected to an oxygen atom at the 4-position to form a phenoxy group. The benzene ring of the phenoxy group has a hydroxyl group (-OH) at the 4-position and an iodine atom at the 3,5-position. The other benzene ring is also connected to an iodine atom at the 3,5-position, and the 4-position of the benzene ring is connected to the previous benzene ring through an oxygen atom, and then to the alanine alpha-carbon atom.
In summary, the chemical structure of this compound is based on alanine, and the alpha-carbon atom is connected with a complex iodine-containing phenoxy phenyl substituent. It is connected by an oxygen atom through the two phenyl rings, and the benzene ring has iodine atom and hydroxyl The complexity of its structure reflects the changeable nature of the structure of organic compounds.

3 - [4- (4-hydroxy-3,5-diiodophenoxy) -3,5-diiodophenyl] -alanine, this substance is an organic compound. Its main physical properties are as follows:
In appearance, it is usually a white to light yellow crystalline powder, resembling fine ice crystals, with a fine texture and occasional shimmering in sunlight. The powder is gently twisted in the hand, resembling fine sand, but it is softer.
In terms of melting point, it is roughly between 195-200 ° C. When the temperature approaches this range, the substance gradually melts from a solid state to a liquid state, and changes from a regular crystalline structure to a flowing state.
In terms of solubility, it is slightly soluble in water, just like a light boat on the surface of a vast river, and can only be integrated into a little. However, in organic solvents, such as ethanol and dichloromethane, it has good solubility, and can dissolve in water like salt, blend with the solvent, and disperse evenly.
In terms of stability, it is relatively stable at room temperature and pressure, just like a calm old man, not moved by slight changes in the outside world. However, in the case of high temperature, strong acid, and strong alkali environment, its structure is like a fragile porcelain bottle, which is easily damaged, chemically reacts, and causes the original properties to change.
This compound has applications in medicine, chemical industry and other fields due to its unique physical properties. It can be used as a key intermediate in pharmacies and contribute to the development of new drugs. In the chemical industry, or participate in the synthesis of special materials, it shows its extraordinary value.

3 - [4 - (4 - hydroxy - 3,5 - diiodophenoxy) - 3,5 - diiodophenyl] - alanine, the Chinese name is often iodophenyl acid, which is widely used in the field.
Iodophenyl acid is an oral cystogram. Gu Yun: "Those who are good, benevolence is also." The development of iodophanic acid can solve the suffering of life. Iodophanic acid on the bed can make the capsule clear under X-ray. If you want to distinguish the shape and size of the capsule, or check its disease, such as cysts and inflammation, iodophanic acid can be used.
The principle is that oral iodopanoic acid is absorbed in the stomach tract, replaced by liver, and then excreted from the juice into the capsule. Due to its high iodine content, it can change the absorption difference of X radiation around the capsule, so that it can clearly improve the capsule profile and help the patient's disease.
Furthermore, in some research fields, iodopanoic acid can also be used as a tool to study the juice substitution and the physiological function of the capsule. For example, exploring the excretion of juice, the replacement of iodopanoic acid, etc., all have important implications for development. Therefore, this is an indispensable position in both research and research.

The preparation of 3- [4- (4-hydroxy-3,5-diiodophenoxy) -3,5-diiodophenyl] -alanine requires a multi-step and delicate operation.
At the beginning, suitable phenolic compounds are often used as raw materials, such as phenols with specific substituents. When the structure of this phenol is related to the intermediate structure of the target product, the subsequent reaction can be easily carried out. First, the phenolic compounds and iodine are reacted under specific reaction conditions. The choice of iodine source can be a mixed system of potassium iodide and potassium iodate. In an acidic environment, the two react to produce iodine elemental substances, and then undergo electrophilic substitution reaction with phenols. The key to this reaction is to control the ratio of the reaction temperature to the reactant. Generally, the reaction temperature is usually maintained at a moderate low temperature, such as between 0 and 10 ° C, to ensure that the iodine atom selectively replaces the adjacent and para-position of the phenolic hydroxyl group to generate 3,5-diiodophenolic derivatives.
Then, the obtained 3,5-diiodophenolic derivatives are reacted with halogenated alkanes. The halogenated alkanes need to be related to the carbon chain structure of the target product, such as selecting an appropriate halogenated propanol. The reaction is carried out under alkaline conditions with a suitable base, such as potassium carbonate, in an organic solvent. The purpose of this reaction is to introduce the corresponding carbon chain on the phenolic hydroxyl group to form 4- (4-hydroxy-3,5-diiodophenoxy) -halopropane derivatives. During the reaction, attention should be paid to the control of the reaction time and temperature. Generally, the reaction temperature is 40-60 ° C, and the reaction time is about several hours to ensure the full progress of the reaction.
Next, the 4- (4-hydroxy-3,5-diiodophenoxy) -halopropane derivative is oxidized. A suitable oxidant, such as potassium permanganate, can be selected. In a suitable reaction system, the terminal hydroxyl group of halopropane is oxidized to a carboxyl group to obtain a 4- (4-hydroxy-3,5-diiodophenoxy) -propionic acid derivative. This oxidation reaction requires control of the amount of oxidant and reaction conditions to prevent excessive oxidation.
Finally, the 4- (4-hydroxy-3,5-diiodophenoxy) -propionic acid derivative is reacted with the ammonia source. Ammonia gas or ammonia water can be selected as the ammonia source. Under certain temperature and pressure conditions, the carboxyl group reacts with ammonia to generate 3- [4- (4-hydroxy-3,5-diiodophenoxy) -3,5-diiodophenyl] -alanine. After this reaction, it needs to be separated and purified, such as recrystallization, column chromatography and other methods to obtain high-purity target products.

This is 3- [4- (4-hydroxy-3,5-diiodophenoxy) -3,5-diiodophenyl] -alanine. Its safety and toxicity are related. Although ancient books do not contain this specific thing, it can be determined according to common sense and related pharmacy.
Looking at its chemical structure, it contains a group of diiodine. Although iodine is a trace element required by the human body, excessive intake may cause thyroid and other diseases. This compound contains a polyiodine structure, or has an impact on human metabolism.
In terms of safety, if it enters the human body, whether it can be metabolized smoothly, and whether there is any risk of accumulation, it is unknown. If it is difficult to metabolize in the body, or accumulates in organs and tissues, it may cause lesions over time.
In terms of its toxicity, the complex structure may make it have special chemical activities. or interact with biological macromolecules such as proteins and nucleic acids in the body to disrupt the normal physiological functions of cells. Or affect the activity of enzymes and cause disorders of metabolic pathways. And contain iodine structure or cause immune-related adverse reactions such as allergies.
Although there is no empirical evidence to prove its exact safety and toxicity, it is inferred from the chemical structure and pharmaceutical theory that its use in the human body should be done with caution. It needs to undergo rigorous experimental studies to carefully investigate its metabolism and toxic reactions in the body before it can be used in related fields.