What is 3,5,3 '-triiodothyronine?
3% 2C5% 2C3 '-triiodothyronine is a type of hormone secreted by the human thyroid gland. It plays a crucial role in many key physiological processes such as growth and development, metabolism regulation, etc.
This hormone is produced by the coupling of one molecule of iodothyronine and one molecule of diiodothyronine. Its activity is much higher than that of thyroxine. It can quickly bind to intracellular receptors and affect the function of various tissues and organs by regulating gene transcription.
In terms of growth and development, it has a significant effect on the development of the nervous system and skeletal system. If children lack this hormone, it can cause mental retardation, short stature and other stunts.
In the field of metabolism, it can improve the basal metabolic rate, increase the body's oxygen consumption and calorie production, and accelerate the metabolic rate of carbohydrates, fats and proteins. For example, patients with hyperthyroidism will experience hypermetabolic symptoms such as overeating, weight loss, and sweating when the hormone level is increased; while patients with hypothyroidism will experience symptoms such as chills, fatigue, and weight gain due to reduced hormone levels.
Clinically, the detection of 3% 2C5% 2C3 '-triiodothyronine in the blood is an important basis for diagnosing diseases such as hyperthyroidism and hypothyroidism, and is of great significance for guiding treatment and evaluating curative effects.
What are the main physiological functions of 3,5,3 '-triiodothyronine?
3,5,3 '-triiodothyronine is a key component of thyroid hormones and plays an important role in the regulation of human physiology. Its main physiological functions are as follows:
First, regulate metabolism. This substance can significantly improve the basal metabolic rate, promote the body's cells to use energy more efficiently, and accelerate the metabolic rate of carbohydrates, fats and proteins. For example, it can accelerate lipolysis and supply energy to the body; it can also improve the absorption and utilization of sugar, and maintain the dynamic balance of blood sugar levels.
Second, it affects growth and development. In the infant stage, 3,5,3' -triiodothyronine is particularly critical for the development of the nervous system and bones. If children do not secrete enough of this hormone, it is easy to cause nerves, resulting in mental retardation, short stature and other serious consequences.
Third, it has an effect on the nervous system. It can improve the excitability of the nervous system and make the body respond more acutely to external stimuli. When the secretion of this hormone increases, people often show symptoms such as emotional agitation and insomnia; when the secretion is reduced, they may appear listlessness, drowsiness and other conditions.
Fourth, it is related to the cardiovascular system. It can enhance the contractility of the heart, increase the heart rate, and increase the output of the heart. Therefore, when the thyroid gland is hyperactive, the burden on the heart increases, which is easy to cause cardiovascular symptoms such as heart palpitations; when the thyroid gland is hypoactive, the heart activity will weaken.
Fifth, it acts on the digestive system. It can promote gastrointestinal peristalsis, improve the secretion function of digestive glands, and help digestion and absorption of food. If thyroid hormone secretion is abnormal, the digestive system will also be affected, or cause constipation, diarrhea and other symptoms.
In short, 3,5,3 '-triiodothyronine plays an indispensable role in many aspects of human physiological activities and is of great significance for maintaining the normal physiological state of the body.
What is the clinical significance of the detection of 3,5,3 '-triiodothyronine?
3% 2C5% 2C3 '-triiodothyronine (T3) is a type of hormone secreted by the thyroid gland, which plays a key role in many physiological processes such as human metabolism, growth and development. In clinical practice, the detection of this hormone has the following important significance:
One is related to the evaluation of thyroid function. When the thyroid gland is hyperactive, the synthesis and secretion of thyroid hormone in the body increases, and the level of T3 is often increased; when the thyroid gland is hypoactive, the secretion of thyroid hormone is reduced, and the level of T3 is usually reduced. Therefore, the detection of T3 can help doctors to judge whether the thyroid is hyperthyroidism or hypothyroidism, and then provide a key basis for the diagnosis of diseases.
The second is also valuable for the diagnosis and monitoring of some non-thyroid diseases. In severe diseases such as acute myocardial infarction, liver cirrhosis, and diabetic ketoacidosis, T3 levels may change abnormally, presenting the so-called "low T3 syndrome". Through the detection of T3, doctors can gain a more comprehensive understanding of the patient's condition, evaluate the severity of the disease and the prognosis.
Three are indispensable for monitoring the treatment effect of thyroid diseases. During the treatment of hyperthyroidism or hypothyroidism, doctors adjust the drug dose in a timely manner according to the changes in T3 and other thyroid function indicators to ensure the effectiveness and safety of the treatment, and promote the patient's thyroid function to return to normal levels as soon as possible.
In conclusion, the clinical detection of 3% 2C5% 2C3 '-triiodothyronine is of great significance, providing key information for the diagnosis, treatment and monitoring of thyroid diseases and related diseases, and is like a powerful tool for doctors to gain insight into the disease and help them develop more accurate and effective diagnosis and treatment plans for patients.
What are the possible causes of abnormal levels of 3,5,3 '-triiodothyronine?
3% 2C5% 2C3 '-triiodothyronine level is abnormal, the reason is investigated, or the following reasons exist.
First, it is because of endowment. People are born with different constitutions, or have innate defects such as viscera deficiency and qi and blood insufficiency, which involve thyroid function, resulting in abnormal production and metabolism of triiodothyronine.
Second, disordered diet. Too much food is cold, fat and sweet, or causes dysfunction in the transportation and transformation of the spleen and stomach, deficiency of qi and blood biochemistry, and affects thyroid hormone synthesis. Or iodine intake is unbalanced. Iodine is a raw material for thyroid hormone synthesis. Iodine deficiency or excess iodine can disrupt thyroid hormone secretion and cause abnormal triiodothyronine levels.
Third, emotional disorders. Long-term worry and anger, emotional disorders, cause liver qi stagnation, qi depression and fire, burn yin, and then affect the qi and blood of the viscera, involve the thyroid function, and cause the level of triiodothyronine to be abnormal.
Fourth, external evils invade. Wind cold, wind heat and other external evils take advantage of the void and form in front of the neck, accumulate heat, damage the thyroid gland, affect its normal function, and cause abnormal levels of triiodothyronine.
Fifth, long-term illness and the transformation of other diseases. His visceral disease persists, involving the kidney, kidney yin and kidney yang deficiency, unable to nourish and warm the thyroid gland, or long-term illness consumes qi and hurts blood, qi and blood deficiency, affects thyroid function, resulting in abnormal levels of triiodothyronine.
In summary, the level of 3% 2C5% 2C3 '-triiodothyronine is abnormal, which is mostly caused by the interaction of various factors such as endowment, diet, emotion, externality and long-term illness.
What diseases can be caused by abnormal 3,5,3 '-triiodothyronine?
3% 2C5% 2C3% 27 -Triiodothyronine (T3), thyroxine (T4), free triiodothyronine (FT3) if abnormal, often can cause a variety of serious diseases.
The husband's thyroid gland, the main gland of the human body, its secretion of T3, T4 and FT3, related to all kinds of physiological ability. If these three are abnormal, one is prone to hyperthyroidism. In hyperthyroidism, thyroid hormone secretion is excessive, resulting in hypermetabolism. Patients often feel palpitations, sweating, weight loss, hand trembling, and irritability, sleep and eating restlessness. Second, hypothyroidism is also common. This is due to the insufficient secretion of thyroid hormones, the body's metabolism slows down, and the patient has chills, fatigue, drowsiness, edema, facial swelling, and hair loss easily.
Furthermore, if these three abnormalities are found in pregnant women, it will be a great disaster. It may cause premature birth and miscarriage, and also affect the neurological and intellectual development of the fetus, which can lead to diseases such as dementia in offspring. And when children grow and develop, thyroid hormone imbalance will hinder their bone and intellectual growth, affecting life.
As for thyroid nodules, thyroiditis, etc., it is also associated with abnormalities of T3, T4, and FT3. The formation of nodules may stimulate glandular hyperplasia due to hormonal disorders; during thyroiditis, inflammation affects the secretion function of the glands, causing hormone levels to fluctuate.
Therefore, the regularity of T3, T4, and FT3 is related to human health. Doctors should carefully observe, and patients should also pay attention. If there is a slight abnormality, it should be diagnosed and treated early to avoid serious diseases.