3 7 Dihydro 5 Iodo 4 Oxo 4h Pyrrolo 2 3 D Pyrimidine
Iodobenzene

3,7-dihydro-5-iodo-4-oxo-4h-pyrrolo[2,3-d]pyrimidine

Fengxi Chemical

Specifications

HS Code

604629

Chemical Formula C6H4IN3O
Molecular Weight 263.02 g/mol
Physical State Solid (usually)
Appearance Off - white to yellowish solid
Melting Point N/A (specific value may vary, needs experimental determination)
Boiling Point N/A (decomposes before boiling in normal conditions)
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
Pka N/A (relevant acid - base properties need experimental determination)
Stability Sensitive to light and air
Chemical Formula C6H4IN3O
Molar Mass 275.016 g/mol
Appearance Solid (predicted)
Melting Point No data
Boiling Point No data
Solubility In Water Low (predicted)
Logp 0.44 (predicted)
Pka No data
Density No data
Uv Vis Absorption Absorption bands in UV region (predicted based on structure)
Chemical Formula C6H4IN3O
Molecular Weight 263.02 g/mol
Appearance Solid (predicted)
Melting Point No data available
Boiling Point No data available
Solubility Solubility in water is low (predicted)
Pka No data available
Logp Positive value indicating lipophilicity (predicted)
Density No data available
Stability Stable under normal conditions (predicted), may decompose on heating or under strong acidic/basic conditions
Chemical Formula C6H4IN3O
Molecular Weight 263.02
Iupac Name 5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-one
Appearance Solid (predicted)
Boiling Point Decomposes
Melting Point 290 - 295 °C
Solubility Soluble in DMSO, slightly soluble in ethanol
Logp -0.79 (predicted)
Pka 11.08 (predicted)
Density 2.22 g/cm³ (predicted)
Packing & Storage
Packing 5 - gram vial of 3,7 - dihydro - 5 - iodo - 4 - oxo - 4H - pyrrolo[2,3 - d]pyrimidine, tightly sealed.
Storage Store 3,7 - dihydro - 5 - iodo - 4 - oxo - 4H - pyrrolo[2,3 - d]pyrimidine in a cool, dry place, away from heat sources and direct sunlight. Keep it in a tightly sealed container to prevent exposure to moisture and air, which could potentially lead to decomposition or degradation of the chemical. Store in a location separate from incompatible substances to avoid chemical reactions.
Shipping 3,7 - dihydro - 5 - iodo - 4 - oxo - 4H - pyrrolo[2,3 - d]pyrimidine is shipped in accordance with chemical regulations. It's carefully packaged to prevent breakage and leakage, often in sealed containers, and transported by carriers licensed for handling such chemicals.
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3,7-dihydro-5-iodo-4-oxo-4h-pyrrolo[2,3-d]pyrimidine 3,7-dihydro-5-iodo-4-oxo-4h-pyrrolo[2,3-d]pyrimidine 3,7-dihydro-5-iodo-4-oxo-4h-pyrrolo[2,3-d]pyrimidine
General Information
Frequently Asked Questions
What are the chemical properties of 3,7-dihydro-5-iodine-4-oxo-4H-pyrrolido [2,3-d] pyrimidine
3% 2C7-dicyano-5-chloro-4-oxo-4H-pyrano [2,3-d] pyrimidine is an organic compound with unique chemical properties.
This compound contains cyanyl, chlorine atom, carbonyl and heterocyclic structures, which endow it with various chemical activities. Cyanyl is a strong electron-absorbing group, which changes the electron cloud density distribution of the molecule, affects its reactivity, and makes it easy to participate in nucleophilic substitution, addition and other reactions. Chlorine atoms are active and can be replaced by nucleophiles under appropriate conditions. New functional groups are introduced to expand the derivativeness of compounds.
Carbonyl groups are polar and can participate in carbonyl-related classical reactions, such as nucleophilic addition, which reacts with nucleophilic reagents such as alcohols and amines to form new compounds. The heterocyclic structure of 4H-pyrano [2,3-d] pyrimidine, which contains multiple nitrogen atoms and unsaturated bonds, endows molecules with aromaticity and basicity, and can participate in proton transfer and coordination reactions. In the fields of organic synthesis and medicinal chemistry, it is often used as a key structural unit because it can interact with specific parts of biological macromolecules.
Its chemical properties make it have potential applications in drug development, materials science and other fields. In drug development, lead compounds with specific biological activities can be designed based on their structural modifications, such as by changing substituents to adjust affinity with biological targets; in materials science, their reactivity can be used to construct functional materials, such as polymerization to prepare polymer materials with special optical and electrical properties.
What are the main uses of 3,7-dihydro-5-iodine-4-oxo-4H-pyrrolido [2,3-d] pyrimidine
3,7-Dihydro-5-chloro-4-oxo-4H-pyrrolido [2,3-d] pyrimidine has a wide range of main uses. In the field of medicine, it is often used as a key intermediate to assist in the synthesis of many drugs. For example, in the development of anti-cancer drugs, the structural properties of this compound can participate in the construction of molecular structures with specific targeting, and interfere with the growth, proliferation and metastasis of cancer cells by acting on specific targets of cancer cells, providing an effective way to overcome cancer problems. In the development of antiviral drugs, it can interact with key enzymes in the process of virus replication by virtue of its unique chemical structure, inhibit the replication and transmission of viruses, and thus contribute to antiviral therapy.
In the field of agriculture, it also has important uses. It can be used as an important raw material for the synthesis of new pesticides. The synthesized pesticides may have special repellent or toxic effects on certain pests, which can effectively control crop pests, ensure the healthy growth of crops, and improve crop yield and quality. At the same time, it may also play a role in regulating plant growth, such as regulating the growth stages of plants such as flowering and fruiting, helping agriculture to achieve more scientific and efficient planting management.
What is the synthesis method of 3,7-dihydro-5-iodine-4-oxo-4H-pyrrolido [2,3-d] pyrimidine
The synthesis method of 3% 2C7-dicyano-5-bromo-4-oxo-4H-pyrizo [2,3-d] pyrimidine is a crucial topic in the field of organic synthetic chemistry. Its synthesis pathways are diverse, and different pathways have their own advantages and disadvantages. Often choose carefully according to actual needs and conditions.
Common synthesis methods, or start from basic raw materials and gradually build the target molecular structure by multi-step reactions. For example, with a compound containing a pyrimidine ring structure as the starting material, bromine atoms can be introduced at a specific position after halogenation. The control of the halogenation reaction conditions is extremely critical, and factors such as reaction temperature, reagent dosage and reaction time need to be paid attention to in order to ensure the precise positioning of bromine atoms.
Then, cyanide is introduced at a suitable check point through cyanation. In the cyanation reaction, the cyanide reagent and reaction solvent selected have a significant impact on the reaction yield and selectivity. And the reaction process may require catalyst assistance to improve the reaction rate and efficiency.
To construct a pyran ring structure, a suitable cyclization reaction is required. This cyclization reaction may involve the process of intra-molecular cyclization, during which the spatial structure and electronic effects of the reactants have a significant effect on the reaction process. Or by adjusting the reaction conditions, such as changing the pH of the reaction medium, adding specific additives, etc., to optimize the cyclization reaction and increase the proportion of the target product.
Or another strategy is adopted, using the compound of the pre-constructed pyran ring as the starting material, and then introducing the pyrimidine ring and other substituents in turn. This process also requires fine regulation of the reaction conditions at each step to ensure the smooth progress of the reaction and the efficient synthesis of the target product.
When synthesizing 3% 2C7-dicyano-5-bromo-4-oxo-4H-pyrizo [2,3-d] pyrimidine, the intermediates must be strictly separated and identified at each step to ensure that the reaction proceeds according to the expected path. And in the overall synthesis route design, factors such as atomic economy, simplicity of reaction steps and convenience of operation should be considered, and efficient and green synthesis methods should be developed.
What is the market price of 3,7-dihydro-5-iodine-4-oxo-4H-pyrrolido [2,3-d] pyrimidine?
I don't know the price of the product you said "3% 2C7-dioxo-5-azole-4-oxo-4H-imidazolo [2,3-d] pyrimidine" in the market. However, according to "Tiangong Kaiwu", the price of everything is often tied to multiple ends.
First, it is related to the material. The scarcity of the material has a great impact on the price. If the material required for this product is rare and difficult to collect, its price will be high; if the material is abundant and easy to obtain, the price may be relatively easy.
Second, it depends on the process. If the process of preparing this "3% 2C7-dioxy-5-azole-4-oxo-4H-imidazolo [2,3-d] pyrimidine" is complicated, requires multiple processes, takes a long time and has high labor costs, and the price is also high; if the process is simple and requires less manpower and material resources, the price may be slightly lower.
Third, the state of supply and demand is also the key. If there is a strong demand for this product in the market and the supply is limited, the so-called "rare is expensive", its price will rise; if there is little demand and sufficient supply, the price may decline.
It is difficult to determine the market price of the material, process and supply and demand details of "3% 2C7-dioxo-5-azole-4-oxo-4H-imidazolo [2,3-d] pyrimidine". The approximate price can only be known after careful investigation of the source of materials, the simplicity of the process, and the situation of supply and demand.
What are the manufacturers of 3,7-dihydro-5-iodine-4-oxo-4H-pyrrolido [2,3-d] pyrimidine?
3,7-Dihydro-5-chloro-4-oxo-4H-pyrrolido [2,3-d] pyrimidine is an important organic compound, which is widely used in the field of medicinal chemistry and is often an intermediate in drug synthesis. Its preparation involves many chemical processes, and many outstanding chemists and scientific research teams are devoted to the research and production of this compound.
In foreign countries, such as BASF in Germany, its scientific research strength is strong and it has made extraordinary achievements in the field of organic synthetic chemistry. With advanced equipment and cutting-edge technology, they have profound knowledge in the synthesis of nitrogen-containing heterocyclic compounds, and are very likely to participate in the production of 3,7-dihydro-5-chloro-4-oxo-4H-pyrrolido [2,3-d] pyrimidine. Merck & Co., Inc. of the United States is also a well-known pharmaceutical company in the world, and has achieved fruitful results in the research and development of innovative drugs. In order to explore new active pharmaceutical ingredients, Merck may conduct synthetic research and production of such compounds, hoping to develop new drugs on this basis.
In China, the Shanghai Institute of Pharmaceutical Research is a leader. The researchers of this institute have been deeply involved in the synthesis and pharmaceutical activity research of heterocyclic compounds for many years, and have in-depth research on compounds with potential medicinal value such as 3,7-dihydro-5-chloro-4-oxo-4H-pyrrolido [2,3-d] pyrimidine, which is very likely to master the relevant production technology and realize production. In addition, WuXi PharmaTech, as the world's leading "integrated, end-to-end" new drug research and development service platform, relies on its strong chemical synthesis capabilities and rich project experience, and may also be involved in the production and preparation of this compound to provide related products and services to global customers.