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What is the chemical structure of 3-amino-2,4, 6-triiodo-hydrocinnamic Acid?
3-Amino-2,4,6-triiodo-hydrocinnamic Acid is 3-amino-2,4,6-triiodophenylpropionic acid. Its chemical structure is as follows:
The core structure of this compound is propionic acid with a benzene ring. The propionic acid structure is\ (CH_ {3} CH_ {2} COOH\), which is connected by methylene\ (- CH_ {2} -\) between the benzene ring and the carboxyl group to form the basic structure of phenylpropionic acid.
Looking at the benzene ring again, each of the 2,4,6 positions is connected to an iodine atom. The iodine atom has a large atomic radius and electronegativity, which has a great influence on the distribution of electron clouds in the benzene ring and the physical and chemical properties of compounds.
The 3-position is connected with an amino group\ (- NH_ {2}\). The amino group is basic and can participate in many chemical reactions, such as salting with acids, participating in nucleophilic substitution, etc. Its existence also affects molecular polarity and biological activity.
Overall, the chemical structure of 3-amino-2,4,6-triiodophenylpropionic acid is a combination of benzene ring, carboxyl group, amino group and iodine atom. The interaction of each group endows this compound with unique chemical and physical properties. It may have important applications in organic synthesis, medicinal chemistry and other fields.
What are the physical properties of 3-amino-2,4, 6-triiodo-hydrocinnamic Acid
3-Amino-2,4,6-triiodo-hydrocinnamic Acid is 3-amino-2,4,6-triiodophenylpropionic acid. This physical property is particularly important and is related to its wide application.
Looking at its physical properties, at room temperature, it is mostly solid, like a powder, fine and uniform. Its color is white or nearly white, and its color is pure.
When it comes to solubility, it is limited in water, but it has a certain solubility in organic solvents such as ethanol and acetone. Ethanol, with its intermolecular force, can interact with some groups of 3-amino-2,4,6-triiodophenylpropionic acid to promote its dispersion and dissolution. The melting point of
is also a key physical property. After fine determination, it can reach a specific temperature. At this point, the substance gradually melts from solid to liquid. This temperature range is its inherent property and can be used as a basis for identification and purification.
Its density is also of characterization significance. Under specific conditions, it has a certain value, reflecting the compactness of its molecules. This density value needs to be considered in the preparation, separation and other processes.
As for its stability, it is still stable in the conventional environment. In case of strong light, hot topics or specific chemical reagents, its structure may change. Under the hot topic, the molecular thermal motion intensifies and chemical bonds may be broken.
In summary, the physical properties of 3-amino-2,4,6-triiodophenylpropionic acid, such as morphology, solubility, melting point, density and stability, are interrelated, and its synthesis, storage, and application are all indispensable factors to consider.
What are the common uses of 3-amino-2,4, 6-triiodo-hydrocinnamic Acid?
3 - amino - 2,4,6 - triiodo - hydrocinnamic Acid, Chinese name 3 - amino - 2,4,6 - triiodophenylpropionic acid, is a chemical compound. This compound is often used in the field of chemical synthesis.
In this field, it is often used as a raw material for imaging. For imaging, it can make specific organs or organs clearer in imaging (such as X-ray, CT, etc.). 3-Amino-2,4,6-triiodophenylpropionic acid contains three iodine atoms, the atomic number of iodine is high, and the absorption capacity of X radiation is high. Therefore, the contrast of this raw material can be effectively changed by injecting it into the human body. The absorption difference of X radiation can be effectively changed, and the helper can clearly observe the human body, so as to prevent diseases.
In the field of chemical synthesis, it is also important. Because its molecules contain amino-carboxyl groups and other active groups, it can be used for the synthesis of many compounds with specific biological activities or functions, such as acetylation and esterification. This compound, due to its special characteristics, plays an indispensable role in chemical synthesis and other aspects, promoting the development of the phase domain.
What are the synthesis methods of 3-amino-2,4, 6-triiodo-hydrocinnamic Acid
3-Amino-2,4,6-triiodo-hydrocinnamic Acid is 3-amino-2,4,6-triiodophenylpropionic acid. The synthesis method is as follows:
Compounds containing benzene rings are often selected as starting materials, such as phenylpropionic acid derivatives. The genphenyl ring can provide the basic framework for the subsequent introduction of iodine atoms and amino groups.
The iodine substitution reaction is first carried out to introduce iodine atoms at specific positions in the benzene ring. In this step, iodine elements (\ (I_ {2}\)) and suitable oxidants such as hydrogen peroxide (\ (H_ {2} O_ {2}\)) or nitric acid (\ (HNO_ {3}\)) are often used. In a suitable solvent, such as glacial acetic acid, heat the reaction. The iodine atom undergoes electrophilic substitution on the benzene ring. According to the positioning rules, iodine atoms are introduced at the 2, 4, and 6 positions of the benzene ring to form intermediates containing 2,4,6-triiodophenylpropionic acid. This process requires precise control of the reaction temperature, time, and the proportion of reactants to prevent excessive substitution or side reactions.
Then the amination reaction is carried out. For the introduction of amino groups, there are two common methods. One is through nitro reduction. First, the iodized phenylpropionic acid derivative is nitrified with a nitrifying agent, such as a mixed acid of concentrated nitric acid and concentrated sulfuric acid, and the nitro group is introduced at a suitable position. After the reduction of nitrobenzene, such as iron powder and hydrochloric acid system, or catalytic hydrogenation, the nitro group is reduced to an amino group, so as to obtain the target product 3-amino-2,4,6-triiodophenylpropionic acid. The second is to introduce an amino group by an aminolysis reaction. Select a suitable halogenated phenylpropionic acid derivative (the halogen atom can be chlorine, bromine, etc.), react with ammonia under suitable conditions, and the halogen atom is replaced by an amino group, and the target product can also be obtained. This process requires attention to the effect of reaction conditions on the purity and yield of the product. Each step of the
synthesis requires appropriate analytical methods, such as thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC), etc., to monitor the reaction process to ensure that the reaction proceeds as expected, and the product is separated and purified, such as recrystallization, column chromatography, etc., to achieve high purity.
What are the precautions for 3-amino-2,4, 6-triiodo-hydrocinnamic Acid in storage and transportation?
3-Amino-2,4,6-triiodine-hydrogenated cinnamic acid is an important chemical substance, and many key matters need to be paid attention to during storage and transportation.
First, when storing, find a cool, dry and well-ventilated place. If this substance is exposed to high temperature or humid environment, it may cause deterioration. High temperature will make its chemical properties active and accelerate decomposition; humid air may cause it to absorb moisture, affecting purity. For example, if stored in a hot and humid warehouse, within a few months, its properties may change and its purity will decrease.
Second, it should be strictly separated from oxidants, acids, bases, etc. Due to its chemical structure characteristics, contact with the above substances is highly susceptible to chemical reactions, or serious consequences such as fire and explosion. For example, if it coexists with a strong oxidant, a slight carelessness, or due to slight friction or collision, will cause a violent reaction.
Third, the storage place should be equipped with suitable materials for containing leaks. In case of leakage, it can be properly handled in time to avoid pollution of the environment and reduce harm. Such as preparing sand, vermiculite, etc., can effectively absorb leaking liquids.
Fourth, the transportation process must ensure that the container does not leak, collapse, fall, or damage. Because of its certain chemical activity, damage to the container is prone to leakage, endangering the safety of transportation personnel and the surrounding environment.
Fifth, when transporting, you need to follow the specified route and do not stop in densely populated areas and residential areas. To prevent accidents during transportation, which pose a huge threat to the lives and property of many people. And transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment in order to deal with emergencies.
