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What are the chemical properties of 3-bromo-4 '-iodine-1,1' -biphenyl?
The chemical properties of 1,1 '-binaphthalene-3,3' -disulfonic acid are as follows:
This substance has a sulfonic acid group, and the sulfonic acid group (\ (- SO_ {3} H\)) is a strong acidic group, which imparts acidic properties to the compound. In aqueous solutions, the sulfonic acid group can ionize and release hydrogen ions (\ (H ^{+}\)), make the solution acidic and can neutralize with the base to generate the corresponding sulfonate and water. For example, with sodium hydroxide (\ (NaOH\)):\ (C_ {20} H_ {14} O_ {6} S_ {2} + 2NaOH = C_ {20} H_ {12} O_ {6} S_ {2} Na_ {2} + 2H_ {2} O\).
Its sulfonic acid group can also participate in the reverse reaction of the sulfonation reaction, and under certain conditions, the reaction of desulfonation may occur. However, this reaction usually requires special conditions, such as under specific catalysts, temperatures and pressures. The
1,1 '-binaphthalene part imparts a certain spatial structure and aromaticity to the compound. Due to the existence of the binaphthalene structure, the compound has a certain rigidity and a special three-dimensional configuration. This three-dimensional structure will affect its selectivity in some reactions, such as in some organic synthesis reactions, it may participate in the reaction as a chiral ligand, using its unique spatial structure to control the chirality of the reaction product and realize asymmetric synthesis.
In terms of solubility, because it contains polar sulfonic acid groups, it has a certain solubility in water, but with the relatively large molecular weight of the organic group (binaphthalene part), its solubility in organic solvents will also be affected. Generally, it has better solubility in polar organic solvents such as dimethyl sulfoxide (DMSO) and N, N-dimethylformamide (DMF), while it has poor solubility in non-polar organic solvents such as n-hexane and benzene.
In addition, 1,1 '-binaphthalene-3,3' -disulfonic acid is relatively stable in some redox reactions, but the binaphthalene part may be oxidized under the action of a specific strong oxidant, resulting in the destruction of the naphthalene ring structure and the formation of corresponding oxidation products.
What are the preparation methods of 3-bromo-4 '-iodine-1,1' -biphenyl?
There are many methods for preparing 1,1 '-binaphthalene, which are detailed below:
First, the metal catalytic coupling method. This is a commonly used method, using transition metals (such as palladium, nickel, etc.) as catalysts to promote the coupling reaction of halogenated naphthalene compounds. If 2-bromonaphthalene is used as raw material, in the presence of palladium catalyst and ligand, in a suitable base and solvent system, the coupling can be achieved to generate 1,1' -binaphthalene. This method has high selectivity and good yield, but the catalyst cost is high, the reaction conditions are more severe, and the reaction equipment and operation requirements are very strict. The relevant reaction formula can be recorded as: 2 2 -bromonaphthalene + Pd catalyst + ligand + base → 1,1 '-binaphthalene + other by-products.
Second, organic synthesis method. It can be achieved by multi-step organic reaction. The naphthalene ring is first functionalized in a specific way, and then a carbon-carbon bond is formed through intramolecular or intermolecular reactions to synthesize 1,1' -binaphthalene. For example, the acyl group is introduced through the acylation reaction of naphthalene, and then the target product is prepared by a series of reactions such as reduction, dehydration and coupling. This approach is flexible and can modify the structure of the product. However, the steps are complicated, and the total yield is easily affected by the multi-step reaction and decreases.
Third, biosynthesis method. Using the catalytic properties of microorganisms or enzymes to synthesize 1,1 '-binaphthalene. Enzymes in some microorganisms can catalyze the oxidative coupling reaction of naphthalene substrates to generate 1,1' -binaphthalene. This method is green and environmentally friendly, with mild reaction conditions and high stereoselectivity. However, the screening and cultivation of biological catalysts is time-consuming and laborious, and the scale of the reaction is limited.
Fourth, electrochemical synthesis method. Under electrochemical conditions, using naphthalene compounds as raw materials, an oxidative coupling reaction occurs on the electrode surface to generate 1,1 '-binaphthalene. This method does not require the addition of additional chemical oxidants or reducing agents, is environmentally friendly, the reaction conditions are relatively mild, and it is easy to adjust. However, it requires high electrochemical equipment, and the selection of electrode materials and the optimization of the reaction system are crucial.
In which fields is 3-bromo-4 '-iodine-1,1' -biphenyl used?
1,1 '-Binaphthalene has applications in many fields such as medicine, materials science, asymmetric catalysis, etc. The following is expressed in classical Chinese as Jun Chenzhi:
In the field of medicine, 1,1' -binaphthalene and its derivatives are often the key elements for creating effective medicines. Due to its unique molecular structure, it can precisely fit with specific targets in organisms, just like the combination of mortise and tenon. For example, in the development of some antidepressant drugs, 1,1 '-binaphthalene-derived structures can effectively regulate the transmission of neurotransmitters, relieve the symptoms of depression in patients, just like a spring breeze, moisturizing the heart.
As for the field of materials science, 1,1' -binaphthalene also shines brightly. It can be integrated into polymer materials, giving the material unique optical and electrical properties. The resulting new materials, in the field of optoelectronic displays, such as liquid crystal displays, can optimize the display effect, make the image clearer and more colorful, just like a wonderful pen to add color to the picture.
Especially important, in the field of asymmetric catalysis, 1,1 '-binaphthalene is a gem. Asymmetric catalysis aims to selectively synthesize compounds of specific configurations, while 1,1' -binaphthalene-derived catalysts, like skilled craftsmen, can precisely guide the direction of the reaction and generate the target product with high selectivity. Many organic synthesis reactions, with the help of such catalysts, can obtain the required chiral compounds efficiently and with high purity, which is of great significance in the chemical, pharmaceutical and other industries, and is a powerful tool to promote industrial progress.
From this point of view, 1,1 '-binaphthalene is widely used in the above fields and plays a significant role, injecting vigorous vitality into the development of many industries. It is a rare and important compound.
What are the physical properties of 3-bromo-4 '-iodine-1,1' -biphenyl?
1,1 '-Binaphthalene has unique physical properties, which are described in detail below.
It has excellent optical properties and significant optical rotation. Because the single bond rotation between the two naphthalene rings of 1,1' -binaphthalene is blocked, a stable chiral structure is formed, which makes the compound optically active to polarized light. Therefore, in the field of asymmetric synthesis, 1,1 '-binaphthalene and its derivatives are often used as chiral ligands or chiral catalysts, which can induce chemical reactions to selectively generate products of specific configurations, which greatly promotes the development of organic synthesis chemistry.
In terms of solubility, 1,1 '-binaphthalene is insoluble in water, which is due to the fact that its molecular structure is mostly hydrophobic hydrocarbon groups, and it is difficult to form effective interactions with water molecules. However, it is soluble in common organic solvents such as chloroform, dichloromethane, toluene, etc. This solubility characteristic allows it to be uniformly dispersed in a suitable organic solvent system in organic synthesis operations, participating in various reactions, and also easy to purify by selecting a suitable solvent for recrystallization and other operations.
In terms of thermal stability, 1,1' -binaphthalene has high thermal stability. The naphthalene ring structure in its molecule has a certain conjugated system, which makes the chemical bonds in the molecule relatively stable, and can maintain the integrity of the structure at a higher temperature, and is not easy to decompose or rearrange. This property enables it to exist as a stable structural unit in some organic reactions or material processing under high temperature conditions, providing protection for the realization of related reactions or material properties.
In addition, 1,1 '-binaphthalene also has certain fluorescence properties. Under the excitation of specific wavelengths of light, it can emit fluorescence. This fluorescence property makes it show application potential in the fields of fluorescent probes, luminescent materials, etc., which can be used to detect specific substances or as a component of luminescent materials to realize optical signal indication or functional regulation of specific systems.
What are the market prospects for 3-bromo-4 '-iodine-1,1' -biphenyl?
Since the modern era, the business path has changed, and the world is bustling, all for profit; the world is bustling, all for profit. The market prospect of 1,1 '-binaphthalene is really related to the interests of many parties, and it is also the focus of attention of all businesspeople.
The current situation is that 1,1' -binaphthalene is widely used in the field of chemical industry. It is often a key raw material in the process of organic synthesis and can help to obtain many delicate compounds. In terms of drug research and development, the creation of many new pharmaceuticals relies on 1,1 '-binaphthalene as the base, so the pharmaceutical industry has a strong demand for it. And in the field of material science, materials made of 1,1 '-binaphthalene have outstanding properties, or have special optical and electrical properties. They have also emerged in the field of optoelectronics, which is due to the profound potential for market expansion.
Furthermore, in terms of the pattern of global trade, the smooth flow of international trade has enabled the transaction of 1,1' -binaphthalene to cross mountains and seas. All countries in the East and West have been involved in this industry. However, there are also variables in the meantime. The production of raw materials, the innovation and progress of processes, and the strictness and tightness of government orders can all affect the situation of their markets. If the origin of raw materials encounters a famine or the government imposes sudden restrictions, the supply may be tight, and the price may jump; if the process has a breakthrough, the cost may drop, and the competition in the market will become more intense.
However, overall, in response to the advance of science and technology in the times, 1,1 '-binaphthalene continues to explore new frontiers in emerging fields. Its market prospects are just like the rising sun. Although there may be clouds and fog temporarily obscured, it will eventually shine brightly. In the chemical industry, medicine, materials and other industries, it continues to rejuvenate, bringing rich benefits to all merchants and becoming the key to the competition in the business sea.