3-chloro-5-iodobenzonitrile

3-Chloro-5-iodobenzonitrile is an important intermediate in organic synthesis. It has a wide range of uses and has extraordinary applications in many fields such as medicine, pesticides, and materials.
In the field of medicine, this compound is often the key raw material for the synthesis of new drugs. Due to the unique chemical properties of halogen atoms (chlorine and iodine) and cyanobenzonitrile, it is endowed with specific reactivity and biological activity. Complex drug molecular structures can be constructed through various chemical reactions to develop therapeutic drugs for specific diseases. For example, for some difficult diseases, chemists can explore innovative drugs with high efficiency and low toxicity through chemical modification of 3-chloro-5-iodobenzonitrile, which can contribute to human health and well-being.
In the field of pesticides, it also plays an important role. Because its chemical structure can exhibit unique biological activities against insects, pathogens and other harmful organisms, it can be used as the basis for the development of new pesticides. Through ingenious structure optimization and synthesis, it is expected to develop environmentally friendly, efficient and highly targeted pesticide products, which can help agricultural production resist pest attacks, improve crop yield and quality, and ensure food security.
In the field of materials science, 3-chloro-5-iodobenzonitrile can participate in the synthesis of special functional materials. Its functional groups can react with other compounds to form materials with special electrical, optical or mechanical properties. For example, in the field of optoelectronic materials, through rational design and synthesis, it is expected to produce luminescent materials or semiconductor materials with excellent performance, which will play an important role in cutting-edge fields such as electronic display and optoelectronic devices, and promote the progress and development of science and technology.
In summary, 3-chloro-5-iodobenzonitrile has shown great application potential in many fields due to its unique chemical structure and reactivity, and has become an important compound in the field of organic synthetic chemistry.

3-Chloro-5-iodobenzonitrile is one of the organic compounds. Its physical properties are quite important and are related to many chemical uses and reaction characteristics.
First of all, its appearance, under room temperature and pressure, 3-chloro-5-iodobenzonitrile is mostly white to light yellow crystalline powder, which is easy to store and use. In many chemical reactions, the powdered substance can provide a large reaction contact area, which is conducive to the progress of the reaction.
The melting point is about 100-104 ° C. The melting point is the characteristic constant of the substance, which is of great significance in the identification and purification of this compound. If you want to obtain high-purity 3-chloro-5-iodobenzonitrile, you can precisely control the temperature, use the characteristics of the melting point, and recrystallize to achieve the purpose of purification.
In terms of boiling point, under specific pressure conditions, its boiling point is different. However, under common conditions, due to the relatively large molecular mass of the compound and strong intermolecular forces, its boiling point is quite high. High boiling point means that under conventional heating conditions, it is not easy to volatilize, relatively stable, and can maintain its own structure in high temperature chemical reaction environments, participating in specific reaction processes.
Solubility is also a key physical property. This compound has a certain solubility in common organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF). In dichloromethane, due to the non-polar of dichloromethane and the non-polar of the partial structure of 3-chloro-5-iodobenzonitrile, the compound can be well dissolved. This property can be used in the extraction, separation and other operation steps of organic synthesis to achieve effective separation and purification.
Furthermore, its density is also an important parameter. Although the exact value will vary slightly due to the measurement conditions, it is generally within a certain range. Density information provides indispensable data support for the quantitative reaction, material ratio and phase separation of the compound, which is helpful for accurately controlling the reaction process and product quality.
In summary, the physical properties of 3-chloro-5-iodobenzonitrile, such as appearance, melting point, boiling point, solubility and density, play a key role in many fields such as organic synthesis and medicinal chemistry, laying a solid foundation for in-depth research and rational use of this compound.

The synthesis method of 3-chloro-5-iodobenzonitrile covers a variety of paths. One of its classics is to use benzonitrile as the initial substrate and perform a halogenation reaction first. Under appropriate reaction conditions, chlorine reagents such as copper chloride can be used to introduce chlorine atoms into specific positions in the benzene ring when assisted by catalysts. After that, iodine reagents, such as iodine elementals, are combined with appropriate oxidants, such as hydrogen peroxide, so that iodine atoms are also connected to the benzene ring. After fine regulation, the formation of the target molecule 3-chloro-5-iodobenzonitrile is achieved.
There are also benzene as the starting material. The formyl group is first introduced through the Fu-Ke acylation reaction to obtain the benzaldehyde derivative. Then, the aldehyde group is converted into the nitrile group by the nitrile reaction. Then, the chlorination and iodine reactions are carried out in steps or at the same time to obtain the product. This path requires detailed control of the reaction conditions of each step, such as reaction temperature, reaction time, and reagent dosage, etc., to ensure the smooth progress of each step of the reaction and achieve a high yield.
Furthermore, a coupling reaction strategy may be used. Using chlorobenzene derivatives and iodine-containing benzene derivatives as raw materials, under the action of transition metal catalysts such as palladium catalysts, with the assistance of suitable ligands, a carbon-carbon bond coupling reaction is carried out to generate the target product. Although this method has the advantage of atomic economy, it requires strict reaction conditions, and the selection of catalysts and ligands is also crucial. All factors need to be carefully weighed to optimize the synthesis process. All synthesis methods have their own advantages and disadvantages, and they need to be selected according to specific needs, raw material availability, cost considerations and other factors.

3-Chloro-5-iodobenzonitrile is a chemical commonly used in organic synthesis. When storing this substance, many key things need to be paid attention to to to ensure its stability and safety.
First, it should be stored in a cool and dry place. Because the substance is more sensitive to heat, high temperature can easily cause it to decompose, which will damage its quality and purity. Similarly, humid environments can also have adverse effects on it, or cause reactions such as hydrolysis, so the dryness of the storage environment is crucial.
Second, 3-chloro-5-iodobenzonitrile needs to be placed in a dark place. Light can induce chemical reactions and cause changes in its structure. For this reason, it is advisable to pack in opaque containers or store them in a dark place to minimize the damage caused by light.
In addition, when storing, pay attention to isolation from other chemical substances. This substance may chemically react with certain oxidants, reducing agents, acids, bases, etc., so it cannot be stored with these substances to prevent accidental reactions.
In addition, the choice of storage container is also very critical. Containers should be made of corrosion-resistant materials to avoid reactions with 3-chloro-5-iodobenzonitrile. At the same time, it is necessary to ensure that the container is well sealed to prevent the substance from evaporating or reacting with the outside air components.
Finally, the storage site should be equipped with corresponding safety facilities and emergency treatment equipment. In the event of an unexpected situation such as leakage, it can be dealt with quickly and effectively, thereby reducing the hazard. Staff also need to be familiar with relevant emergency treatment methods in order to respond correctly in an emergency. In this way, the safety and stability of 3-chloro-5-iodobenzonitrile during storage can be guaranteed.

I look at your question about the market price of 3-chloro-5-iodobenzonitrile. However, the market price of this chemical often changes due to many reasons, making it difficult to determine.
First, the trend of supply and demand determines its price. If the demand for this product in the market increases greatly, and the supply is limited, the price will increase; conversely, if the supply exceeds demand, the price may decrease.
Second, the price of raw materials is also a major factor. The production of this chemical requires specific raw materials. If the price of raw materials increases, the production cost increases, and the market price is also high; if the price of raw materials decreases, the price may decrease.
Third, the preparation method and technology can also affect its price. Advanced and efficient preparation techniques can reduce costs and make prices lower; while complex and inefficient methods may lead to high costs and high prices.
Fourth, the price varies from region to region. The economic conditions, transportation costs, tax policies, etc. vary from place to place, resulting in different prices in different regions.
In summary, if you want to know the exact market price of 3-chloro-5-iodobenzonitrile, you should consult chemical product suppliers, traders, or professional chemical market information platforms to get near real-time and accurate prices.