3 Fluoro 4 2 Iodothieno 3 2 B Pyridin 7 Yloxy Benzenamine
Iodobenzene

3-fluoro-4-(2-iodothieno[3,2-b]pyridin-7-yloxy)benzenamine

Fengxi Chemical

Specifications

HS Code

894628

Chemical Formula C16H10FIN2OS
Molecular Weight 426.23
Appearance Solid (predicted)
Boiling Point Predicted to be high due to molecular complexity
Melting Point Data may vary based on purity and measurement conditions
Solubility Limited solubility in water, better in organic solvents like DMSO
Logp Predicted to have a relatively high logP value, indicating lipophilicity
Pka Data might be available from experimental measurements for acidic or basic groups
Stability Should be stored in a cool, dry place away from light and oxidizing agents
Ir Absorption Characteristic absorption bands in IR spectrum for functional groups like -NH2, C=O (if present), etc.
Chemical Formula C16H10FIN2OS
Molecular Weight 424.14
Appearance Solid (predicted)
Solubility In Water Low (predicted)
Logp High (predicted)
Vapor Pressure Low (predicted)
Chemical Formula C16H10FIN2OS
Molecular Weight 426.13
Appearance Solid (predicted)
Boiling Point N/A (experimental), can be estimated based on structure
Melting Point N/A (experimental), can be estimated based on structure
Solubility In Water Low (due to non - polar nature of the molecule)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Density N/A (experimental), can be estimated based on structure
Pka N/A (experimental), can be estimated based on functional groups
Logp High (lipophilic, due to large aromatic structure)
Stability Stable under normal conditions, may decompose under extreme heat or strong oxidizing agents
Chemical Formula C16H10FIN2OS
Molecular Weight 424.23 g/mol
Appearance Solid (predicted)
Solubility In Water Low (predicted)
Solubility In Organic Solvents Soluble in common organic solvents (predicted)
Logp High (predicted)
Packing & Storage
Packing 100g of 3 - fluoro - 4-(2 - iodothieno[3,2 - b]pyridin - 7 - yloxy)benzenamine in sealed chemical - grade pouch.
Storage Store "3 - fluoro - 4 - (2 - iodothieno[3,2 - b]pyridin - 7 - yloxy)benzenamine" in a cool, dry place away from heat sources and direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and exposure to air, which could potentially cause degradation. Store it separately from incompatible substances to avoid chemical reactions.
Shipping The chemical "3 - fluoro - 4 - (2 - iodothieno[3,2 - b]pyridin - 7 - yloxy)benzenamine" will be shipped in properly sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations to ensure safety during transit.
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3-fluoro-4-(2-iodothieno[3,2-b]pyridin-7-yloxy)benzenamine 3-fluoro-4-(2-iodothieno[3,2-b]pyridin-7-yloxy)benzenamine 3-fluoro-4-(2-iodothieno[3,2-b]pyridin-7-yloxy)benzenamine
General Information
Frequently Asked Questions
What is the chemical structure of 3-fluoro-4- (2-iodothieno [3,2-b] pyridin-7-yloxy) benzenamine?
This is the name of the organic compound, and its corresponding chemical structure, let me explain it in detail for you.
First look at "3-fluoro-4- (2-iodothieno [3,2-b] pyridin-7-yloxy) benzenamine", "benzenamine" indicates that the main body of this compound is an aniline structure, that is, a phenyl ring-linked amino ($- NH_ {2} $). " 3-Fluo "means that the third position of the benzene ring is substituted by a fluorine atom ($F $), and" 4 - (2 - iodothieno [3,2 - b] pyridin - 7 - yloxy "means that the fourth position of the benzene ring is connected to a complex group.
In this complex group," thieno [3,2 - b] pyridin "is a thiopheno [3,2 - b] pyridine structure, which is formed by fusing a thiophene ring with a pyridine ring." 2-Iodo "indicates that thiopheno [3,2-b] pyridine has an iodine atom ($I $) substituted at position 2, and" 7-yloxy "indicates that the fused ring at position 7 is connected to the benzene ring through an oxygen atom ($O $).
In summary, the chemical structure of this compound is: aniline as the parent body, benzene ring at position 3 is connected to a fluorine atom, and at position 4 is connected to a 2-iodothiopheno [3,2-b] pyridine group through an oxygen atom.
What are the main uses of 3-fluoro-4- (2-iodothieno [3,2-b] pyridin-7-yloxy) benzenamine?
3-Fluoro-4- (2-iodothieno [3,2-b] pyridin-7-yloxy) benzenamine, an organic compound. Its main use is crucial in today's chemical and pharmaceutical fields.
In the process of drug development, it is often used as a lead compound. Due to its unique structure, it contains fluorine atoms, iodine atoms, and the structure of thiophenopyridine linked to benzene rings, giving it unique physical, chemical and biological activities. Scientists can explore its interaction with biological targets by modifying its structure to search for potential drug molecules with higher activity, better selectivity and lower toxicity. For example, in the development of anti-cancer drugs, such compounds containing specific heterocycles and halogen atoms may be able to precisely act on specific targets of cancer cells and inhibit the growth and spread of cancer cells.
In the field of materials science, this compound can also be used. Due to its particularity of structure or unique photoelectric properties, it can be used to prepare organic optoelectronic materials, such as organic Light Emitting Diode (OLED), organic solar cells, etc. The introduction of fluorine atoms may improve the stability and electron transport properties of materials, while iodine atoms can adjust the electron cloud distribution of molecules, thereby optimizing the photoelectric conversion efficiency of materials.
In chemical synthesis research, it is an important intermediate. Chemists can use their diverse reaction check points to construct more complex organic molecular structures through various chemical reactions. On this basis, the methods and strategies of organic synthesis are expanded, and the variety and structure of organic compounds are enriched.
In summary, 3-fluoro-4- (2-iodothieno [3,2-b] pyridin-7-yloxy) benzenamine has important uses in many fields such as drug development, materials science and chemical synthesis, providing a key material basis and research direction for the development of related fields.
What are the physical properties of 3-fluoro-4- (2-iodothieno [3,2-b] pyridin-7-yloxy) benzenamine?
3-Fluoro-4- (2-iodothiopheno [3,2-b] pyridine-7-yloxy) aniline, which is an organic compound. To clarify its physical properties, it is necessary to look at it from various aspects.
The first appearance of this compound is that it may be in the form of a solid powder at room temperature and pressure, but it also depends on its intermolecular forces, crystal structure and other factors. If the intermolecular action is strong and the arrangement is orderly, it is easy to be solid, and the color may be white or nearly colorless. This is due to the lack of significant influence of chromophore groups in the molecular structure.
On the melting point, the molecule contains fluorine, iodine and other halogen atoms, as well as benzene ring and heterocyclic structure, and the intermolecular force is complex. Halogen atoms can increase the polarity of the molecule and increase the van der Waals force; while there is π-π accumulation between aromatic rings, which increases the melting point. Roughly presumed, its melting point may be in a higher temperature range, but the exact value needs to be accurately determined by experiments.
In terms of boiling point, the molecule has a certain complexity and relatively high molecular weight. In addition, there are polar groups, and the intermolecular force is strong. In order to make it boil to overcome the attractive force between molecules, high energy is required, so the boiling point should not be low.
In terms of solubility, because it contains polar amine groups, it can form hydrogen bonds with water, and may have a certain solubility in polar solvents such as methanol, ethanol, acetone, etc. However, there are also large non-polar parts in the molecule, such as benzene ring, thiophene and pyridine ring, which may have a certain solubility in non-polar solvents such as n-hexane and toluene, but in general, the solubility in water may be inferior to that of polar organic solvents.
Density is related to the molecular weight and the degree of molecular packing. Molecules contain heavy atom iodine, which increases molecular weight, and the structure or makes the molecular packing more compact, so the density may be relatively large.
In addition, the compound contains fluorine, iodine and other halogen atoms, which can affect its refractive index, making it different from common organic compounds.
In summary, the physical properties of 3-fluoro-4- (2-iodothiopheno [3,2-b] pyridine-7-yloxy) aniline are influenced by the interaction of various groups in the molecular structure. Although the structure can be slightly speculated, the exact value still depends on the experimental measurement.
What is the synthesis of 3-fluoro-4- (2-iodothieno [3,2-b] pyridin-7-yloxy) benzenamine?
The synthesis of 3-fluoro-4- (2-iodothieno [3,2-b] pyridine-7-yloxy) aniline is an important task in organic synthetic chemistry. To prepare this substance, the following steps can be followed.
First, the key intermediate needs to be prepared. Using thiopheno [3,2-b] pyridine as the starting material, the iodine atom is introduced into the 2-position through halogenation reaction. In this halogenation reaction, suitable halogenating reagents can be selected, such as iodine elemental substance and appropriate oxidizing agent. Under suitable reaction conditions, such as in a specific solvent, the temperature and reaction time can be controlled to precisely connect the iodine atom to the 2-position of thiopheno [3,2-b] pyridine.
Second, prepare fluorophenoxy intermediates. Using 3-fluoro-4-hydroxyaniline as the starting material, the substitution reaction occurs with appropriate halogenated hydrocarbons to form 3-fluoro-4- (haloalkoxy) aniline. The choice of this haloalkoxy group needs to be considered according to the subsequent reaction, and the activity and selectivity of the reaction should be ensured.
Then, the 2-iodothieno [3,2-b] pyridine intermediate obtained above is coupled with the 3-fluoro-4- (haloalkoxy) aniline intermediate. This coupling reaction can be selected from a palladium-catalyzed coupling reaction system, such as the Buchwald-Hartwig coupling reaction. In the reaction, it is necessary to precisely control the amount of palladium catalyst, the type and amount of ligands, the type and amount of bases, as well as the reaction solvent, temperature and time, so that the two intermediates can be successfully coupled to generate the target product 3-fluoro-4- (2-iodothiopheno [3,2-b] pyridine-7-yloxy) aniline.
After the reaction is completed, the product needs to be separated and purified. Common separation and purification methods such as column chromatography and recrystallization can be used to obtain high-purity target products. Through this series of steps, 3-fluoro-4- (2-iodothieno [3,2-b] pyridine-7-yloxy) aniline can be obtained.
What is the market outlook for 3-fluoro-4- (2-iodothieno [3,2-b] pyridin-7-yloxy) benzenamine?
Today, there is a product named 3-fluoro-4- (2-iodothieno [3,2-b] pyridin-7-yloxy) benzenamine. The prospect of this product in the market is related to many parties and needs to be examined in detail.
From the perspective of the pharmaceutical field, its unique structure or pharmacological activity can open up a new path for the development of new drugs. Today's pharmaceutical industry is eager for novel compounds, hoping that they can treat intractable diseases. This compound contains fluorine, iodine and other elements, and its characteristics are significant, or it is helpful for the development of targeted therapeutic drugs. It is expected to solve the problems of tumors and other diseases. Therefore, the pharmaceutical market has infinite potential.
In the field of materials science, due to the coexistence of heterocycles and benzene rings in its structure, or with special electrical and optical properties. Nowadays, the demand for electronic and optical materials is increasing, and it may be used to make new semiconductor materials and improve the performance of electronic devices; or it may be used in the field of optical display to improve the display effect, and the market prospect is promising.
However, the road ahead for its market is not smooth. Synthesizing this compound may require complex processes and high costs, making mass production difficult. And the market competition is fierce. If new compounds want to stand out, they must undergo strict testing and approval. However, over time, if they can overcome technical problems, reduce costs and increase efficiency, they will surely shine in the market and bring innovation to related industries.