3 Fluoro 4 Iodobenzoic Acid
Iodobenzene

3 Fluoro 4 Iodobenzoic Acid

Fengxi Chemical

Specifications

HS Code

445506

Chemical Formula C7H4FIO2
Molar Mass 268.01 g/mol
Appearance Solid (likely white or off - white)
Physical State At Room Temperature Solid
Melting Point Data may vary, need specific experimental value
Boiling Point Data may vary, need specific experimental value
Solubility In Water Low solubility, as it is a relatively non - polar aromatic carboxylic acid derivative
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone, dichloromethane
Pka Value Data may vary, need specific experimental value (carboxylic acid group is acidic)
Density Data may vary, need specific experimental value
Flash Point Data may vary, need specific experimental value
Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents
Chemical Formula C7H4FIO2
Molar Mass 268.009 g/mol
Appearance Solid
Melting Point 135 - 139 °C
Solubility In Water Low
Solubility In Organic Solvents Soluble in common organic solvents like DMSO, DMF
Cas Number 100753-19-3
Packing & Storage
Packing 500g of 3 - fluoro - 4 - iodobenzoic acid packaged in a sealed, chemical - resistant container.
Storage 3 - fluoro - 4 - iodobenzoic acid should be stored in a cool, dry place away from direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and contact with air, which could potentially lead to degradation. Store it separately from incompatible substances, such as strong oxidizing agents and bases, to avoid chemical reactions. Ensure the storage area has good ventilation.
Shipping 3 - fluoro - 4 - iodobenzoic acid is shipped in well - sealed, corrosion - resistant containers. Packaging adheres to strict chemical shipping regulations. Shipment is via approved carriers to ensure safe and proper transportation.
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3-fluoro-4-iodobenzoic Acid 3-fluoro-4-iodobenzoic Acid 3-fluoro-4-iodobenzoic Acid
General Information
Frequently Asked Questions
What are the chemical properties of 3-fluoro-4-iodobenzoic Acid?
3-Fluoro-4-iodobenzoic acid, this is an organic compound. It is acidic, because the carboxyl group can ionize hydrogen ions. In chemical reactions, the carboxyl group can participate in many reactions, such as neutralization with bases to form corresponding carboxylic salts and water; esterification with alcohols to form esters and water.
The fluorine atoms and iodine atoms in this compound also affect its chemical properties. Fluorine atoms have high electronegativity and have an electron-sucking induction effect, which can reduce the electron cloud density of the benzene ring and change the activity of electrophilic substitution reactions on the benzene ring. Although iodine atoms have lower electronegativity than fluorine atoms, their atomic radius is large, and they can participate in some special reactions. For example, iodine can undergo nucleophilic substitution reactions under specific conditions and be replaced by other nucleoph
In addition, benzene ring, as a stable conjugate system, endows this compound with certain aromaticity, which affects its reactivity and selectivity. This substance may have important uses in the field of organic synthesis, and can be used as an intermediate to synthesize more complex organic compounds. By reacting with carboxyl groups, fluorine atoms and iodine atoms, organic molecules with diverse structures can be constructed.
What are the main uses of 3-fluoro-4-iodobenzoic Acid?
3-Fluoro-4-iodobenzoic acid, which is one of the organic compounds. Its main uses are quite extensive, and today it is the first one for you.
First, in the field of pharmaceutical synthesis, this compound is often used as a key intermediate. Due to its unique chemical structure, it can participate in the construction of many drug molecules. For example, in the development of some new drugs with specific pharmacological activities, 3-fluoro-4-iodobenzoic acid can be ingeniously embedded in the molecular structure of the drug through a series of chemical reactions, giving the drug unique properties, such as enhancing the affinity between the drug and the target, and improving the efficacy of the drug. It can be seen in the synthesis of many anti-cancer drugs and antibacterial drugs, making great contributions to human health.
Second, in the field of materials science, 3-fluoro-4-iodobenzoic acid also has important applications. In the preparation of organic optoelectronic materials, it can be used as a basic raw material to participate in the synthesis. After specific processing, the derived materials may have excellent optical and electrical properties, and can be applied to the fabrication of organic Light Emitting Diodes (OLEDs), solar cells and other devices. Such materials may improve the key performance indicators such as luminous efficiency and stability of devices, and promote the progress of materials science and related electronic devices.
Third, in the field of fine chemicals, this compound is also an indispensable raw material. Used in the synthesis of various fine chemicals, such as special dyes, fragrances, etc. Taking dye synthesis as an example, 3-fluoro-4-iodobenzoic acid participates in the synthesis of dyes, which may have unique color, light resistance and dyeing properties to meet the needs of high-quality dyes in textile, printing and other industries. In fragrance synthesis, it may endow fragrances with unique aroma characteristics and enhance the quality and uniqueness of fragrances.
What are the synthetic methods of 3-fluoro-4-iodobenzoic Acid?
The synthesis method of 3-fluoro-4-iodobenzoic acid has been studied by many scholars in the past, and now I will describe the common methods.
One is the halogenation method. First take the appropriate benzoic acid derivative, and carry out the halogenation reaction under suitable reaction conditions with a specific halogenating agent, such as a halogenating agent containing fluorine and iodine. Among them, the choice of reaction solvent is very critical. Common ones such as dichloromethane, N, N-dimethylformamide, etc., depend on the characteristics of the halogenating agent and the needs of the reaction. The reaction temperature also needs to be precisely controlled. If it is too high, the side reactions will increase, and if it is too low, the reaction rate will be delayed. Usually it starts at low temperature and gradually heats up to make the reaction complete. And the dosage ratio of the halogenating agent also has a great influence on the purity and yield of the product, and it needs to be tested many times to determine the best ratio.
The second is achieved through a coupling reaction. First, the intermediates containing fluorine and iodine are prepared separately, and then the two are connected by coupling reagents, such as palladium catalytic systems. The activity and stability of palladium catalysts are related to the success or failure of the reaction, and the ligands in the reaction system have a significant effect on the performance of palladium catalysts. The type and dosage of bases during the reaction also affect the reaction process, such as potassium carbonate, sodium carbonate and other bases, which can create a suitable alkaline environment and promote the coupling reaction. The reaction process needs to be protected by inert gas to prevent the intermediate and product from being oxidized and affecting the synthesis effect.
The third is an aromatic compound as the starting material, obtained by multi-step functional group conversion. Fluorine atoms are introduced first, then iodine atoms are introduced through a suitable reaction path, and finally carboxyl groups are constructed. In this process, the selectivity of each step of the reaction needs to be carefully considered. If fluorine atoms are introduced, unnecessary effects on other potential reaction check points should be avoided. After each step of the reaction, it must be separated and purified to ensure the purity of the raw materials in the next step, so as to effectively improve the quality and yield of the final product 3-fluoro-4-iodobenzoic acid.
3-fluoro-4-iodobenzoic the market price of Acid
What you are asking is the market price of 3-fluoro-4-iodobenzoic acid. However, this price is not constant and often varies with many factors.
The source of its raw materials is an important factor. If the raw materials are easy to obtain and abundant, the cost may decrease and the price will also fall. On the contrary, if the raw materials are scarce and rare, the cost will rise and the market price will also be high.
The quality of the production process is also related to the price. Advanced and exquisite technology may improve the output efficiency, reduce consumption and improve quality, and make the product price more competitive. If the process is crude and inefficient, the cost will increase and the selling price will increase.
The market supply and demand situation is the key. If there are many seekers and few suppliers, the supply is in short supply, and the price will tend to rise. On the contrary, if there is an oversupply, merchants will sell their goods or reduce prices to compete for the market.
In addition, the industry competition situation also has an impact. The competition between the same industry is fierce, and in order to occupy the market, or use various means, price reduction is a common method. However, exclusive operation, less competitive pressure, the price may be controllable at a higher level.
To determine the current exact market price of this 3-fluoro-4-iodobenzoic acid, check the chemical product trading platform, industry information, or consult the merchant specializing in this chemical. The price may vary depending on the quantity, quality, and time, and must be carefully investigated to obtain the truth.
3-fluoro-4-iodobenzoic Acid during storage and transportation
For 3-fluoro-4-iodobenzoic acid, pay attention to many matters during storage and transportation.
Its nature may be more active and it is afraid of heat. Therefore, when storing, it is advisable to find a cool and dry place, away from direct sunlight, so as not to decompose or cause other chemical reactions due to excessive temperature. If overheated, it may damage its quality and even cause danger.
Furthermore, this substance may be corrosive and must not be inadvertently contacted. During transportation, the packaging must be firm and tight to prevent leakage. The packaging materials used must be resistant to its corrosion and can effectively protect it. Once leaked, it will not only stain the environment, but also cause serious harm to human health, or cause erosion of the skin, respiratory tract, etc.
And because of its special chemical properties, it is appropriate to transport with other chemicals, especially those who react with them, and place them separately and never mix them. In this way, accidental chemical reactions can be avoided and transportation safety can be guaranteed.
The storage area should also be well ventilated to prevent the accumulation of harmful gases. When the staff operates, they must wear suitable protective equipment, such as gloves, protective clothing and goggles, to ensure their own safety. And the storage and transportation places should be equipped with corresponding emergency treatment equipment and materials. If there is an accident, they can respond quickly.