3 Fluoro 5 Iodo Phenylamine

3-Fluoro-5-iodo-phenylamine, Chinese name 3-fluoro-5-iodoaniline, is an organic compound with important uses in many fields.
In the field of medicinal chemistry, it is often used as a key intermediate. Drug developers can create compounds with specific biological activities by modifying and modifying their chemical structures. Taking the development of antibacterial drugs as an example, by introducing specific functional groups on the basis of the structure of 3-fluoro-5-iodoaniline, its antibacterial spectrum and antibacterial activity may be changed, laying the foundation for the birth of new antibacterial drugs.
In the field of materials science, it also has extraordinary performance. It can participate in the preparation of optoelectronic materials, because its special molecular structure endows the material with unique electrical and optical properties. For example, when used in the preparation of organic Light Emitting Diode (OLED) materials, it can improve the luminous efficiency and stability of the device, and contribute to the development of display technology.
In the field of dye chemistry, 3-fluoro-5-iodoaniline can be used as a raw material for the synthesis of special color and performance dyes. By chemically reacting it and introducing different substituents, it can adjust the color, light resistance and washable properties of the dye, meeting the needs of high-quality dyes in textile, printing and other industries.
In scientific research experiments, 3-fluoro-5-iodoaniline is a commonly used reagent for organic synthesis reactions. Chemists use it to participate in nucleophilic substitution, coupling and other reactions to construct more complex organic molecular structures and promote the development of organic chemistry theory and practice. In short, 3-fluoro-5-iodoaniline plays an indispensable role in many fields due to its unique structure and properties, providing support for the progress of science and technology.

3-Fluoro-5-iodine-aniline, which is an organic compound, is very important in various fields of chemistry. Today, its physical properties are described in detail as follows:
First words appearance and properties, under normal circumstances, 3-fluoro-5-iodine-aniline is mostly in a solid state, but its specific appearance may vary depending on purity and crystallization conditions, or it is a white to light yellow crystalline powder, or a lump.
The melting point and boiling point, the melting point, are related to the transition temperature between the solid state and the liquid state of the substance. The melting point of 3-fluoro-5-iodine-aniline is about a specific range, but the exact value has not been studied in detail. However, this temperature is of great significance for the maintenance of its physical state under specific conditions. As for the boiling point, it changes from liquid to gaseous state under a specific pressure environment, which is also a key physical parameter, but the exact boiling point data need to be investigated in detail.
Furthermore, when it comes to solubility, the solubility characteristics of this compound vary in different solvents. Generally speaking, it is in organic solvents such as ethanol, ether, dichloromethane, etc., or has some solubility. The molecular structure and polarity of organic solvents interact with 3-fluoro-5-iodine-aniline, which can make it disperse. In water, due to the difference between the polarity of water and the structure of the compound, its solubility or poor.
The density of the compound, although its exact value is not known, can be inferred from its molecular composition and the properties of similar compounds. The density is related to the quality of the substance per unit volume, and is an important consideration in the separation and mixing of substances.
In addition, the volatility of 3-fluoro-5-iodine-aniline is relatively low. Due to its intermolecular force, it is difficult to evaporate to the gas phase at room temperature and pressure. This characteristic has a certain impact on its stability during storage and use.
At the end of the talk about the smell, although there is no exact record, many organic amine compounds have a special smell, 3-fluoro-5-iodine-aniline or also have a unique amine smell, but the intensity of the smell may vary depending on the concentration.
The physical properties of 3-fluoro-5-iodine-aniline are of great significance in many fields such as organic synthesis and drug development. According to their characteristics, researchers can rationally design experiments and optimize reaction conditions.

The synthesis of 3-fluoro-5-iodine aniline is a regular number method. First, 3-fluoro-5-iodine aniline is obtained by iodine substitution starting with 3-fluoro-5-iodine aniline. In this case, when iodine is substituted, an appropriate iodine source, such as iodine elemental substance (IO2), is synergistically acted with an appropriate amount of oxidant, such as hydrogen peroxide (H2O) or sodium nitrite (NaNO 2O). In a suitable solvent, such as acetic acid or dichloromethane, the temperature is controlled. If the cap temperature is too high, side reactions will occur frequently and the yield will be damaged; if the temperature is too low, the reaction will be slow and take a long time.
Second, benzene is used as the starting material. First, fluorine atoms are introduced to prepare 3-fluoronitrobenzene through nitrification reaction. In this step, a suitable nitrifying agent, such as mixed acid (a mixture of nitric acid and sulfuric acid), is selected. According to the substituent localization rules on the benzene ring, the fluorine atom is the ortho-para localization group, supplemented by conditioning, so that the nitro group is mainly introduced into the 3-position. Then, the nitro group is reduced to an amino group, and the commonly used reducing agents such as iron filings and hydrochloric acid, hydrogen and catalysts (such as palladium carbon) are used to obtain 3-fluoroaniline. Finally, the target product 3-fluoro-5-iodoaniline is prepared as described above.
Or, with 3-fluoro-5-iodobenzoic acid as the starting material, through the amidation reaction, the carboxyl group is converted into an amide group, and then through the Hoffmann degradation reaction, the amide group is converted into an amino group, and 3-fluoro-5-iodoaniline can also be obtained. In this process, the amidation requires the selection of appropriate reagents and conditions. During the Hoffmann degradation reaction, the amount of halogen and base such as bromine (Br ²) or chlorine (Cl ²) and the reaction temperature are all factors related to the reaction effectiveness and yield.
All synthesis methods have their own advantages and disadvantages. It is necessary to comprehensively weigh and choose the optimal method according to the availability of raw materials, cost, difficulty in controlling reaction conditions, yield and purity requirements, etc.

Looking at this question, I am inquiring about the market price of 3-fluoro-5-iodine-aniline. However, it is not easy to understand its price. The market price often changes due to many factors, such as the supply and demand of raw materials, the cost of production, the complexity of the process, the competition in the market, and even the influence of current events.
If we speculate from the past market state, this compound, due to the special atoms such as fluorine and iodine, needs to be prepared by exquisite methods, and the cost is not low. And such aromatic amines containing special halogens are often used in fine chemical fields such as medicine and materials, and the demand may also be considerable.
However, if you want to get an accurate price, you need to study the current market in detail. If the fine chemicals that are similar in the past have similar uses and are equally difficult to prepare, the price may have something to refer to. In the place where chemical raw materials are traded, some clues may be found. However, due to the passage of time and the ever-changing market, its price is also difficult to determine.
Or you can consult a merchant specializing in fine chemicals, or a platform for exploring chemical information, you can get a price closer to the current price. In short, the market price of Ximing 3-fluoro-5-iodine-aniline cannot be obtained without extensive information and detailed market inspection.

3-Fluoro-5-iodoaniline is an organic compound, and many matters need to be paid attention to during storage and transportation.
Bear the brunt, and the storage environment must be cool and dry. This compound is very sensitive to humidity and temperature. High temperature and humid places can easily cause it to deteriorate, affecting quality and purity. For example, if stored in a hot and humid place, chemical reactions may be triggered, resulting in changes in chemical properties. Therefore, a well-ventilated and temperature-stable place should be selected to ensure its stability.
Furthermore, contact with oxidants should be strictly avoided. 3-Fluoro-5-iodoaniline is prone to violent reactions when exposed to oxidants, and may even cause combustion or even explosion. This is as the ancients said "water and fire are incompatible". Oxidants and the compound are like water and fire and cannot coexist. When storing and transporting, make sure to keep it away from common oxidants such as hydrogen peroxide and potassium permanganate.
In addition, due to its certain toxicity, protective measures are essential during storage and transportation. Operators should wear professional protective equipment, such as protective clothing, gloves and protective masks, to prevent contact and inhalation. And the storage area should be clearly marked to remind everyone of its danger.
When transporting, packaging is also crucial. Appropriate packaging materials need to be selected to ensure their sealing and shock resistance. High-quality packaging can effectively avoid package damage due to bumps and collisions during transportation, thereby preventing compound leakage.
Finally, all relevant operations should follow established safety procedures and regulations. Storage and transportation must comply with national and local safety standards, and must not be done without authorization to ensure the safety of personnel and the environment from pollution.