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What is the chemical structure of 3-iodo-1,1,1-trifluoropropane?
3-Iodo-1,1,1-trifluoropropane is also a chemical compound. Among its molecules, propane is the main component of propane. Propane is composed of three carbon atoms and forms a direct phase.
On top of this propane base, the first carbon atom at the end is connected to three fluorine atoms. The fluorine atom is weak and the carbon atom is weak, making this chemical property special. The introduction of fluorine atoms is due to its chemical properties, such as molecular properties, boiling properties, and solubility.
And at the other end, that is, the third carbon atom, is connected to an iodine atom. The iodine atom has a large atomic mass, and its total is also large. The presence of iodine atoms makes the molecule form one of the active sites in the chemical reaction. Due to the small energy phase of carbon-iodine, iodine atoms are easily replaced in suitable components, and the generation of such reactions as nuclear substitution is easy.
Therefore, the chemical reaction of 3-iodo-1,1,1-trifluoropropane is composed of fluorine atoms and iodine atoms at a specific position in the propane skeleton. This gives the chemical properties of the compound. It has certain uses in the field of synthesis and other fields.
What are the main uses of 3-iodo-1,1,1-trifluoropropane?
3-Iodo-1,1,1-trifluoropropane (3-iodo-1,1,1-trifluoropropane) is an organic compound with a wide range of main uses.
First, it plays a significant role in the field of organic synthesis. It can be used as a key intermediate to construct organic molecules with diverse structures. With its unique structure, iodine atoms are highly active in the substitution reaction of halogenated alkanes and are easily replaced by various nucleophiles, thus achieving the construction of carbon-carbon bonds and carbon-heteroatomic bonds. For example, in the synthesis path of building fluorinated drug molecules, through carefully designed reaction steps, this compound can precisely introduce trifluoromethyl and other specific groups, laying the foundation for the creation of new drugs with specific physiological activities.
Second, it also has outstanding performance in materials science. Due to the fluorine atoms in the molecule, the material is endowed with unique physical and chemical properties, such as improving the thermal stability, chemical stability and corrosion resistance of the material. For example, in the preparation of high-performance fluoropolymer materials, 3-iodo-1,1,1-trifluoropropane can be used as a monomer or modifier to participate in the reaction, thereby improving the properties of the polymer, making it suitable for aerospace, electronics and other fields that require strict material properties.
Third, it can be used as a fluorination reagent in some special reactions. Due to the existence of trifluoromethyl in the molecule, the selective fluorination of other compounds can be achieved under suitable reaction conditions, which is of great significance in the field of organic fluorine chemistry research and provides an effective way for the synthesis of compounds with specific fluorination modes.
To sum up, 3-iodo-1,1,1-trifluoropropane, with its unique structure and properties, plays an indispensable role in many fields such as organic synthesis, materials science and organic fluorine chemistry, providing a solid material foundation and technical support for many scientific research and industrial applications.
What are the physical properties of 3-iodo-1,1,1-trifluoropropane?
3-Iodine-1,1,1-trifluoropropane is an organic compound with specific physical properties. It is mostly liquid at room temperature and pressure, with moderate volatility.
Looking at its appearance, pure 3-iodine-1,1,1-trifluoropropane is often colorless and transparent, like clear water, with no visible impurities, showing a pure state.
When it comes to odor, although there is no detailed information to describe it accurately, it is analogous to similar halogenated hydrocarbons, or has a slightly irritating odor. It smells or feels uncomfortable, but it is not intensely pungent.
Its boiling point is about 74-76 ° C. At this temperature, the substance gradually changes from liquid to gaseous. The boiling point value is related to the intermolecular force. The existence of halogen atoms and fluorine atoms makes the intermolecular force different, and the boiling point is in this range.
The melting point is about -70 ° C. The temperature drops below the melting point, and the substance condenses from liquid to solid state. The lower melting point indicates the order of the time division of the solid state and the interaction characteristics between molecules.
In terms of density, its density is relatively high compared to water, about 1.84 g/cm ³. If it is placed in the same container as water, it will sink to the bottom of the water, which is due to the type and structure of atoms in the molecule, resulting in a larger mass per unit volume.
In terms of solubility, 3-iodine-1,1,1-trifluoropropane is insoluble in water. Because water is a polar molecule, and the compound has a certain degree of non-polarity, according to the principle of "similar miscibility", the two are difficult to miscible. However, it is soluble in some organic solvents, such as ether, acetone, etc. The polarity of these organic solvents is more compatible with the compound, and can attract each other through intermolecular forces to achieve dissolution.
What are the synthesis methods of 3-iodo-1,1,1-trifluoropropane?
3-Iodo-1,1,1-trifluoropropane is an organic compound. Its synthesis method is diverse, and you will describe it in detail today.
First, the reaction of halogenated alkanes with nucleophiles can cause its formation. Using 1,1,1-trifluoropropane as the starting material, iodine atoms are introduced through halogenation reaction. For example, under the action of light or initiator, 1,1,1-trifluoropropane reacts with iodine elemental substance to generate 3-iodo-1,1,1-trifluoropropane. The mechanism of this reaction is a radical substitution reaction. The light or initiator prompts the iodine molecule to cleave into iodine radicals, which attack the hydrocarbon bonds of 1,1,1-trifluoropropane and form carbon radical intermediates, which then combine with iodine radicals to obtain the target product. However, the selectivity of this reaction is not good, or side reactions may occur, resulting in impure products.
Second, it can be prepared by substitution reaction of alcohols. First, 3-hydroxy-1,1,1-trifluoropropane is prepared by a suitable method, and then the hydroxyl group is converted into an iodine atom. For example, phosphorus triiodide (PI 🥰) or hydrogen iodide (HI) is used as a reagent to react with 3-hydroxy-1,1,1-trifluoropropane. Taking PI 🥰 as an example, when it reacts with alcohol, it becomes an intermediate, and then nucleophilic substitution occurs, and the hydroxyl group is replaced by an iodine atom to obtain 3-iodo-1,1,1-trifluoropropane. The advantage of this method is that the reaction conditions are relatively mild and the selectivity is good, but the corresponding alcohol needs to be prepared in advance, and the steps may be slightly complicated.
Third, the addition reaction of olefins is also the way of synthesis. Add 1,1,1-trifluoropropene containing double bonds to iodizing reagents. If 1,1,1-trifluoropropene is added to hydrogen iodide in the presence of an appropriate catalyst, according to Markov's rule, iodine atoms are added to double-bonded carbon atoms containing less hydrogen to generate 3-iodo-1,1,1-trifluoropropane. This method has high atomic utilization and simple reaction steps, but the preparation and storage of olefins raw materials may require specific conditions.
Fourth, reactions involving organometallic reagents are also possible. The organometallic intermediate is formed by reacting 1,1,1-trifluoropropyl halide with organolithium reagent or Grignard reagent, and then reacting with iodine substitution reagent, iodine atoms can be introduced to obtain the target product. This method can precisely control the reaction check point and improve the selectivity of the product. However, the organometallic reagent has high activity and demanding reaction conditions. It requires an anhydrous and anaerobic environment, which is inconvenient to operate.
Synthesis of 3-iodo-1,1,1-trifluoropropane has its own advantages and disadvantages. In practical application, it is necessary to comprehensively consider the availability of raw materials, reaction conditions, product purity requirements and other factors to choose a suitable synthesis path.
What are the precautions for storing and transporting 3-iodo-1,1,1-trifluoropropane?
3-Iodo-1,1,1-trifluoropropane is an organic compound. When storing and transporting, it is necessary to pay great attention to ensure safety.
It is flammable and easy to burn in case of open flames and hot topics. Therefore, the storage place must be kept away from fire, heat sources, and well ventilated. The warehouse temperature should not exceed 30 ° C to prevent it from evaporating due to excessive temperature, increasing the risk of combustion and even explosion.
This compound is hazardous to water, and do not let undiluted or large quantities of products come into contact with groundwater, waterways or sewage systems. During transportation, it should be prevented from leaking into the environment. If a leak occurs, measures should be taken quickly to prevent the expansion of pollution.
Because of its lively chemical properties, it needs to be stored separately from oxidants, acids, alkalis, etc., and must not be mixed in storage to avoid violent chemical reactions. The handling process should be handled lightly to avoid damage to packaging and containers and leakage of materials.
When transporting, it should be driven according to the specified route, and do not stop in densely populated areas and residential areas. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment.
Operators need to undergo special training and strictly abide by the operating procedures. It is recommended that operators wear self-priming filter gas masks (half masks), chemical safety glasses, anti-static overalls, and rubber oil-resistant gloves to ensure their own safety.