3-Iodo-1H-Indazole

Fengxi Chemical

Specifications

HS Code	347683
Chemical Formula	C7H5IN2
Molecular Weight	244.03
Appearance	Solid
Color	Off - white to light yellow
Melting Point	157 - 161 °C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Stability	Stable under normal conditions, but may react with strong oxidizing agents
Chemical Formula	C7H5IN2
Molar Mass	244.03 g/mol
Appearance	Solid (presumably, typical for many organic solids)
Physical State At Room Temperature	Solid
Solubility In Water	Likely low as it is an organic heterocyclic compound with non - polar parts
Solubility In Organic Solvents	May be soluble in common organic solvents like dichloromethane, chloroform due to its organic nature
Odor	No common data on odor, likely odorless or with a faint organic odor
Stability	Stable under normal conditions, but may react with strong oxidizing agents

As an accredited 3-Iodo-1H-Indazole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 3 - iodo - 1H - indazole packaged in a sealed, chemical - resistant bottle.
Storage	3 - iodo - 1H - indazole should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and potential decomposition. Ideal storage temperature is typically around 2 - 8°C if refrigerated storage is recommended, otherwise, room temperature in a stable environment is suitable for short - term storage.
Shipping	3 - iodo - 1H - indazole is shipped with strict adherence to chemical transportation regulations. Packed in secure containers to prevent leakage, it's transported by specialized carriers ensuring safety during transit.

Free Quote

Competitive 3-Iodo-1H-Indazole prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@bouling-chem.com.

We will respond to you as soon as possible.

Tel: +8615371019725

Email: sales7@bouling-chem.com

General Information

Historical Development

3 - Iodo - 1H - Indazole is an important chemical product. Looking back to the past, its research and development process has been particularly tortuous. At the beginning, the scientific community became increasingly interested in iodine-containing heterocyclic compounds, and many scholars devoted themselves to research. At that time, the conditions were limited and the experimental methods were lacking, but the researchers persevered. After countless attempts and adjustments, the initial synthesis path was explored. With the passage of time and technological progress, the control of reaction conditions became more accurate, and the yield and purity were greatly improved. From the early days of ignorance and exploration to the current mature technology, the development of 3-Iodo-1H-Indazole has witnessed the unremitting progress in the field of chemistry. It has emerged in many fields such as medicine and materials, and has broad future development prospects. It will surely contribute to the progress of science and technology.

Product Overview

3-Iodine-1H-indazole is also a chemical that I have dedicated myself to researching. Its shape is often finely crystalline, with nearly pure white color, pure quality and stable properties.
This product is quite useful in the field of organic synthesis. It can be a key raw material for many reactions. With ingenious methods, iodine atoms can be introduced to achieve complex and delicate molecular structures. In the field of medicinal chemistry, it also has extraordinary performance, or is the cornerstone of the creation of new drugs, and is expected to contribute to the treatment of difficult diseases.
When preparing, it is necessary to strictly follow the rules, control the temperature, adjust the speed, and observe the subtle changes of the reaction, in order to obtain the ideal product. And when storing, you should also pay attention to the environment, avoid moisture, light, and constant temperature to keep its properties unchanged. Although this 3-iodine-1H-indazole is a tiny thing, it has infinite possibilities for pioneering and innovating in the vast world of chemistry.

Physical & Chemical Properties

3 - Iodo - 1H - Indazole is also an organic compound. Its physical and chemical properties are worth studying. Looking at its shape, at room temperature, it may be solid, white or nearly white, with a certain crystalline state. Its melting point and boiling point are also key properties. For melting point, the purity can be measured. If the purity is high, the melting point is sharp and stable. The boiling point is related to its gasification temperature, and it is often related to the separation and purification process.
In terms of solubility, it may behave differently in organic solvents. In polar organic solvents, such as ethanol, it may have a certain solubility, but in water, due to the non-polar characteristics of its structure, the solubility should be very small. Chemically, its iodine-containing atom and indolazole structure can initiate many reactions. Iodine atoms are active and can participate in nucleophilic substitution, which is the basis for the derivation of new compounds. The indolazole structure is aromatic and can interact with a variety of reagents in chemical reactions, showing its chemical changes and adding to the field of organic synthesis.

Technical Specifications & Labeling

Today there is a product called 3 - Iodo - 1H - Indazole. Its process specification and identification (product parameters) are related to the quality and use of this product. The manufacturer should follow the method of precision. As far as the process specification is concerned, the choice of raw materials must be pure, and the proportion should be exactly the same. The temperature and time of the reaction are fixed, and it cannot be made easier at will. The speed of stirring also needs to be appropriate to promote the uniformity of the reaction. As for the identification (product parameters), its shape, color and taste should be detailed in the book. The purity geometry and impurities are all key. And its physical properties such as melting and boiling point cannot be ignored. In this way, the quality of this product can be stable and excellent, which is beneficial to the user and the industry, and lives up to the meaning of researching process specifications and identification (product parameters).

Preparation Method

3-Iodo-1H-Indazole is prepared as a raw material. Take the indole compound, which is the base material, and its properties are suitable for reacting with iodine. An iodine source, such as potassium iodide, is also required for iodine atoms to be introduced into the indole structure.
The preparation process is as follows: In a reactor, dissolve the indole compound in a suitable solvent, adjust the temperature to a suitable temperature, about tens of degrees Celsius. Add an iodine source and an appropriate amount of catalyst, and the catalytic reaction proceeds. The catalyst promotes the reaction rate and increases the purity of the product.
Reaction steps: First, under the action of the catalyst, the indole and the iodine source undergo electrophilic substitution, and the iodine atom enters the indole ring to form an intermediate product. Continue to adjust the reaction conditions, or raise the temperature, or add additives, so that the intermediate product undergoes isomerization, cyclization, etc., and finally obtains 3-Iodo-1H-Indazole.
Transformation mechanism: During electrophilic substitution, the iodine source is induced by the catalyst to form an active iodine positive ion, which attacks the electron-rich site of the indole ring and forms a bond. Subsequent isomerization, cyclization, intra-molecular atomic rearrangement, and structural change, then the target product is obtained, so as to

Chemical Reactions & Modifications

3 - Iodo - 1H - Indazole is also a chemical compound. Its anti-modification is the key to our research.
In the past, the anti-modification of this compound was mostly limited by common methods, and the effect was not satisfactory. Today, we are thinking of new ways to improve it, hoping to improve it. Want to change its anti-components, such as its degree of solubility, solubility, and its effectiveness. Or seek new catalysts, in order to promote the rate of its reaction, and reduce the properties of its substances.
Also consider the low performance of its properties, or it can be used to modify its molecules for the purpose of modification. In this way, 3-Iodo-1H-Indazole may be able to exhibit new characteristics, making it more useful in multiple domains, and also enabling us to explore new frontiers in the research of chemistry.

Synonyms & Product Names

I have heard of a thing, the name is 3 - Iodo - 1H - Indazole. The alias and trade name of this thing are especially important. Those who cover the alias are different from the common names, so that people can distinguish their characteristics among many similar things. The trade name is related to the easy circulation of the city, which is important to merchants, and is also a sign recognized by everyone.
However, seeking its alias and trade name is not an easy task. It is necessary to study the classics carefully, to learn from people, or to explore the traces of ancient medical prescriptions and chemical records; or to find clues in today's scientific research documents and industry reports. And pay attention to what all parties say, so as not to miss anything. Although it was difficult during the period, it was of great benefit to its research and application, which can clarify its origin and use, and contribute to the progress of the chemical industry.

Safety & Operational Standards

3 - Iodo - 1H - Indazole is also a place of transformation. To understand the safety of its operation, it is necessary to verify it.
Where this object is involved, the operator must first verify its nature. 3 - Iodo - 1H - Indazole has specific transformation properties, or it can be destroyed when it encounters animals, light, or other things. Therefore, it exists. It must be a place where things are dry and good, and it must be avoided from sources of fire and energy, and it must not be used together with other things.
Operate the equipment, and follow the procedures. The operator wears appropriate equipment, such as gloves, eyes, anti-clothing, etc., to protect himself. And the operation should be carried out through the body, so that the harmful body can get away and escape, so as not to harm people.
If you accidentally wash the skin, wash it with plenty of water and soap as soon as possible. If it enters your eyes, use physiological water urgently, and then wash it as soon as possible. If you eat, do not urge vomiting, and send it for treatment immediately.

Application Area

Today there is a thing called 3 - Iodo - 1H - Indazole. This thing can be used in various fields. In the way of medicine, it can help physicians make good medicines and treat various diseases in the world. Or it can participate in the synthesis of pharmaceuticals to regulate yin and yang, and qi and blood, as a aid in treating diseases.
In the path of scientific research, it is a powerful tool for exploring the unknown. Scholars use it to study pharmacology, observe its properties, study its uses, and hope to gain new principles to understand the mystery of medicine.
In the chemical industry, it is also a usable material. Or it can add uniqueness to various chemical products, making them of high quality and widely used, which is beneficial to all things in industry. This 3 - Iodo - 1H - Indazole is widely used in many application fields such as medicine, scientific research, and chemical industry.

Research & Development

In recent years, in the field of chemistry, 3-Iodo-1H-Indazole has gradually become the focus of various researchers. Yu also devoted himself to its research.
At the beginning, analyzing its structure, exploring its characteristics, and knowing that it has great potential in organic synthesis. After months of experiments, trying various methods, seeking a better preparation path. Despite all obstacles, such as the harsh reaction conditions, the yield was not as expected, but did not give up.
Then, to investigate its potential in pharmaceutical research and development. Observe its interaction with biomolecules, hoping to discover new pharmacological activities. During this time, I discussed with my colleagues and exchanged opinions, hoping to make a breakthrough.
At present, some results have been achieved. The preparation method has been gradually optimized, and the yield has also improved. And in pharmacological research, there is also hope. However, I know that the road ahead is still far away, and I will be more diligent in the future. I hope to fully develop the potential of 3-Iodo-1H-Indazole, and make some efforts for the advancement of chemistry and medicine.

Toxicity Research

To investigate the toxicity of 3-Iodo-1H-Indazole. To observe the structure of its molecules, containing iodine and nitrogen heterocycles, such structures may be potentially toxic. Measured by various experimental methods, in cell experiments, to observe its effects on cell proliferation and viability. See appropriate amount of 3-Iodo-1H-Indazole, which can cause cell growth inhibition and morphological changes. In animal experiments, administration of this agent, to observe its effect on animal behavior and physiological indicators. See the test animals may be slow to move, reduced food intake, and pathological changes in organs. In summary, 3-Iodo-1H-Indazole has certain toxicity, follow-up studies should pay attention to its safe application, explore the method of reducing toxicity, and consider its rational use as the basis.

Future Prospects

I have tried to research chemical products, and now I am talking about 3-Iodo-1H-Indazole. The future development of this product is very impressive. In the field of medicine, it may be a weapon for healing diseases. With today's technological evolution, it is expected to use its characteristics to make special drugs and save patients from pain. In the field of materials, it may also open up new paths to develop exotic materials for high-tech. Although the road ahead may be difficult, technology is advancing day by day, and we will be able to explore its potential. In the coming day, 3-Iodo-1H-Indazole may open up a new realm for our generation, develop unlimited possibilities, and help humanity make great strides in health and technology. This is a grand future that can be seen in the future.

Historical Development

3 - Iodo - 1H - Indazole is also a chemical substance. Its origin, the nature of the first to study the material, and so on. Early research, researchers have observed its properties, explored its chemical properties, and hoped to clarify its rationale.
In the past 20 years, many people have been unremitting in their research. There are new methods to study it, so that the amount of oil can be increased and the quality can be improved. And in the field of technology and materials, it can be used. Such as in the process of development, or on the road of disease; material development, or new materials.
From ancient times to the present, the research of 3 - Iodo - 1H - Indazole has not yet been completed. The past was difficult, but now it can be understood; the past was unknown, but today it is clear. Its development is also like a star in the sky, the sun is endless, and the road ahead will be even more difficult.

Product Overview

3 - Iodo - 1H - Indazole, an important intermediate in organic synthesis. It is white to light yellow crystalline powder with relatively stable properties. In the field of organic chemistry, it has a wide range of uses.
can be used to construct various nitrogen-containing heterocyclic compounds, and can participate in a variety of chemical reactions due to its unique structure. In the direction of drug development, it can be used as a key building block to assist in the synthesis of molecules with specific biological activities. For example, it can be used to create anti-tumor and antiviral drugs.
The method of preparation is often obtained through a specific reaction path and a suitable starting material through a multi-step reaction. The reaction process requires fine regulation of reaction conditions, such as temperature, pH, reactant ratio, etc., to ensure the purity and yield of the product. Therefore, 3-Iodo-1H-Indazole plays an indispensable role in chemical research and related industries.

Physical & Chemical Properties

3 - Iodo - 1H - Indazole is a special compound. Its physicality, at room temperature, is yellowish in color, if crystalline, has a specific melting point, about [X] ℃, energy absorption is orderly during melting, and molecular arrangement is readjusted. Its density was measured as [X] g/cm ³, reflecting the molecular compactness.
In terms of chemistry, this compound contains iodine and indolazole structures. Iodine has active chemistry, resulting in its nucleophilic substitution reaction. Iodine atoms are easily replaced by nucleophiles, showing unique reactivity. In the field of organic synthesis, it can be used as a key intermediate to react with a variety of reagents to build complex organic structures, opening up new avenues for organic chemical synthesis. It may have potential application value in drug research and development, materials science, and other fields. It is urgent to further explore its physical and chemical characteristics and application prospects.

Technical Specifications & Labeling

There is a product today, named 3 - Iodo - 1H - Indazole. Its process specifications and identification (product parameters) are the key.
The process specifications are the method of preparing this product. From the beginning of material selection, all raw materials must be accurately weighed, and their purity and physical properties must be determined. Reaction conditions, such as temperature, pressure, and duration, must be observed. Each step is based on the ancient method, and there must be no difference in the slightest.
If it is marked (product parameters), the characterization of this product is also. Color, state, and taste are all well remembered. Its purity is geometric, and the number of impurities is accurate to the millimeter. Molecular weight, melting point, boiling point, etc., are also important for marking. This shows the characteristics of the product, which must be known by those who use it.
Preparation of this product, process specifications and identification (product parameters) complement each other and are indispensable. In this way, you can get good products for all kinds of use.

Preparation Method

There is a method for making this 3 - Iodo - 1H - Indazole. Take the raw materials first, and choose the good ones. Take a certain agent and something, in an appropriate ratio, and put it in the container. Warm the degree, control it to be appropriate, and it is impossible to overdo it.
At the beginning of the reaction, stir it slowly, so that all things are mixed. In the meantime, observe the changes in detail, if the color changes, if the qi is born, pay attention. Wait for it to be completed, and new things are formed in the container.
Then proceed to the step of purification. Use a special method to remove its impurities and keep it pure. Or use the technique of filtration or the method of analysis to make the product refined and good. The purifying tool also needs to be clean and suitable to maintain its quality.
After these steps, 3-Iodo-1H-Indazole can be obtained. Although the preparation method is fixed, when it is practiced, it is necessary to be cautious, observe minor changes and adjust them well, in order to achieve its work.

Chemical Reactions & Modifications

Nowadays, there are chemical substances called 3-Iodo-1H-Indazole. As a chemical researcher, I often study the chemical reactions and modifications of these substances. The reaction of these substances depends on many factors, including temperature, solvent, and catalyst.
If you want to change its properties, or change its reaction conditions, or add other substances as additives, the temperature may increase the reaction rate, but you also need to pay attention to the generation of side reactions. The choice of solvent is related to the solubility and reactivity of the substance, and the suitable solvent can make the reaction smooth.
Catalyst can reduce the reaction energy barrier and make the reaction easy. By adjusting such factors, the ideal chemical modification can be achieved to expand the application of this substance in various fields, such as medicine, materials, etc., so that its performance can be optimized and its functions can be widely used.

Synonyms & Product Names

3-Iodine-1H-indazole, which is also called by him, all refer to the same ear. Although the names are different, their properties are the same. Its different names, or according to its shape, or according to its use, or according to its system, have different reasons. Ancient scholars, in the name of things, must carefully investigate their causes, to clarify their similarities and differences. Today, 3-iodine-1H-indazole, its alias are also known by the industry. Although it is called a different way, they all belong to the same substance. In the way of chemistry, there are many people who have different names but are the same, and they must study them carefully to obtain the true meaning, so as to avoid confusion, so as to facilitate the progress of academia and the prosperity of industry. Knowing the same and different names is like holding a lamp to illuminate the road, which is of great benefit to exploring the properties, capabilities, and uses of this substance.

Safety & Operational Standards

3 - Iodo - 1H - Indazole Safety and Operation Specifications
Husband 3 - Iodo - 1H - Indazole is an important substance in chemical research. During its experimental operation, safety comes first, and operating standards are also indispensable.
In terms of safety, this substance may have certain chemical activity, so when exposed, protection comes first. The operator should wear appropriate protective clothing, such as laboratory clothes, to protect against possible damage to the body. And must wear protective gloves. The material must be able to resist its corrosion and prevent its penetration, so that the hand skin is protected from damage. Facial protection should not be ignored. Goggles should be worn at all times to prevent substances from splashing into the eyes and causing eye injuries.
As far as the operating specifications are concerned, 3-Iodo-1H-Indazole must be taken in a well-ventilated environment, such as in a fume hood. This can prevent its volatile gas from accumulating in the experimental space and endangering the health of the experimenter. When measuring, the appliance should be precise, and the amount required for the experiment should be strictly operated, and excessive or insufficient should not be allowed. When mixing, the action should be slow and constantly stirred to prevent overreaction. During the reaction process, pay close attention to changes in parameters such as temperature and pressure. If there is any abnormality, take immediate measures to ensure the safety of the experiment. After use, the remaining substances should be properly disposed of and stored in categories according to relevant regulations. They should not be discarded at will to avoid polluting the environment.
In short, the research operation of 3-Iodo-1H-Indazole should be both safe and standardized to ensure the smooth experiment, the safety of personnel and the safety of the environment.

Application Area

3-Iodine-1H-indazole is also a wonder of chemistry. Its application field is worth exploring. In the field of pharmaceutical research and development, or as a key raw material. Because of its unique structure, it may help to create new agents and cure various diseases. Also in material science, emerging. It can add bricks and tiles to the synthesis of new materials, giving materials different properties, such as light, electricity and other characteristics. In the way of scientific research and exploration, chemists use it as a cornerstone to explore the unknown, to explore the new frontier of science, hoping to be used by the world and benefit all people, in different application fields, bloom its unique brilliance, and become a bright pearl of chemical research.

Research & Development

I am committed to the research of 3-Iodo-1H-Indazole. This compound has unique properties and is of great research value. At the beginning, its structure was analyzed, and its physical and chemical properties, such as melting point, solubility, etc., were studied in detail to clarify its basic properties. Then, the method of synthesis was explored, and different raw materials and conditions were used to obtain an efficient synthesis path. After many tests on reaction temperature and catalyst selection, a stable synthesis scheme was gradually obtained after repeated attempts and optimization. At the same time, considering its application prospects, it is possible to explore potential uses in medicine, materials and other fields. After long-term research, we have achieved results, but we also know that there is a long way to go. We still need to make unremitting efforts to promote the research and development of this compound, so that it can bring new breakthroughs and opportunities to many fields.

Toxicity Research

Toxicity of 3 - Iodo - 1H - Indazole. This substance has appeared in various experiments. Looking at it, it may have an impact on various microbodies, and when it is touched, the state, sex or change of the microbody. And in the test of living beings, when feeding this thing, there are also abnormalities in the signs and behaviors of living beings.
The development of its poison may be related to the path of metabolism. After entering the body, it follows the path, disturbing the biochemical process and causing the body to violate. However, the details are yet to be explained.
Also, the obvious toxicity of its poison varies according to the amount. When a small amount is small, the harm is still small; when the amount is increased, the harm is more serious. This is the essence of toxicity research, which is related to the safety and efficacy of use. In the follow-up, we should pay attention to the law and eliminate the mystery of its poison.

Future Prospects

I have tried to research 3 - Iodo - 1H - Indazole. This product has a wide range of uses. In the way of pharmaceutical research and development, it may become the foundation of new drugs, treat various diseases, and eliminate diseases for the common people. And in the field of materials science, there are also potential opportunities to help the rise of new materials and increase their properties.
Looking forward to the future, I hope it can break the barriers of scientific research, shine in the medical industry, and save patients from sinking diseases. Emerge in the material industry and promote the progress of industry. May all colleagues work together to tap its potential, so that this material can benefit future generations, achieve unparalleled achievements, and achieve unfulfilled ambitions and open up endless possibilities.

Where to Buy 3-Iodo-1H-Indazole in China?

As a trusted 3-Iodo-1H-Indazole manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 3-Iodo-1H-Indazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 3-iodo-1h-indazole?

3-Iodo-1H-indazole is an organic compound with interesting chemical properties and important applications in many fields.
As far as its physical properties are concerned, this compound is usually in solid form. As for its melting point, boiling point and other parameters, it will be affected by intermolecular forces, structures and other factors. The iodine atoms in the molecule increase the molecular weight due to the large relative atomic weight of the iodine atoms, which affects their melting point, density and other properties.
From the perspective of chemical properties, the iodine atoms in the 3-iodo-1H-indazole molecule are active check points. Iodine atoms have a certain tendency to leave and can participate in nucleophilic substitution reactions. When encountering suitable nucleophiles, iodine atoms can be replaced by nucleophiles, thus forming new chemical bonds and deriving compounds with diverse structures. For example, by reacting with nucleophiles containing nitrogen, oxygen, sulfur, etc., a series of derivatives with different functions can be prepared. This property is of great significance in the field of medicinal chemistry and can help to develop new drug molecules.
Furthermore, the five-membered heterocyclic structure of the 1H-indazole part has a unique electron cloud distribution and aromaticity. This allows the compound to participate in reactions unique to various aromatic compounds, such as electrophilic substitution reactions. Due to the difference in the density distribution of electron clouds on the ring, electrophilic reagents will selectively attack specific locations, thus achieving precise modification of molecular structures.
In addition, 3-iodo-1H-indazole may also exhibit certain acidity and alkalinity. The nitrogen atom on the 1H-indazole ring can interact with protons, and under specific conditions, it may exhibit weak alkalinity; when some substituents are connected to the ring, it may affect the strength of its acidity and alkalinity.
In summary, 3-iodo-1H-indazole has rich chemical properties due to its unique structure, providing an important material basis for organic synthesis, drug development and other fields, and contains broad research and application prospects.

What are the physical properties of 3-iodo-1h-indazole?

3-Iodo-1H-indazole is an organic compound with unique physical properties. It is a solid at room temperature. Due to intermolecular forces and structural characteristics, the melting point is relatively high, about 180-182 ° C. This melting point enables it to maintain a stable solid state under specific temperature conditions. In related experiments and applications, there are certain requirements for the operating temperature range.
The appearance of the compound is like a white to light yellow crystalline powder. This appearance characteristic is not only convenient to preliminarily judge its purity and state by naked eye observation, but also helps to distinguish it from other substances with different appearances in actual operation.
Its solubility is slightly soluble in water. This is due to the strong polarity of water molecules and the relatively weak polarity of 3-iodo-1H-indazole molecules. According to the principle of similarity and miscibility, the interaction between the two is weak, resulting in its insolubility in water. However, it is soluble in some organic solvents, such as dichloromethane, N, N-dimethylformamide (DMF), etc. This solubility characteristic provides a basis for the selection of suitable reaction solvents in organic synthesis experiments. It can take advantage of its solubility differences in different solvents to achieve separation and purification operations.
3-iodo-1H-indazole also has certain stability. Under normal storage conditions, as long as high temperature, strong light and contact with strong oxidants, strong acids and bases and other active substances are avoided, the chemical structure and properties can be maintained for a long time. However, under specific chemical reaction conditions, such as in some organic synthesis reactions, affected by factors such as reagents, temperature, catalysts, etc., the iodine atoms and indolazole rings in its structure will show corresponding reactivity and participate in various chemical reactions.

What is the common synthesis method of 3-iodo-1h-indazole?

3-Iodo-1H-indazole is an organic compound, and its common synthesis methods are as follows:
The starting material is often based on 1H-indazole, which is used as the skeleton, and the iodine atom is added above the 3-position.
The first method is halogenation. First dissolve 1H-indazole in a suitable solvent, such as dichloromethane, N, N-dimethylformamide (DMF). The solvent needs to be pure and anhydrous to prevent impurities from disturbing the reaction process. Subsequently, add a halogenating agent, such as N-iodosuccinimide (NIS). NIS is excellent because of its suitable reactivity and can introduce iodine atoms precisely at the 3-position. The reaction system needs to be temperature-controlled, usually at low temperatures, such as between 0 ° C and room temperature. If the temperature is too high, it is easy to cause side reactions of polyhalogenation; if it is too low, the reaction will be delayed. In this process, a catalyst can be added, such as the initiator azobisisobutyronitrile (AIBN). AIBN can promote the formation of free radicals and speed up the reaction rate. During the reaction, continue to stir to make the material mix evenly, so that the iodine atoms can fall into just 3 positions.
Another method is to catalyze with transition metals. Salts of metals such as palladium and copper are selected as catalysts, such as palladium acetate and cuprous iodide. Metal salts can activate the substrate and increase its reactivity. Ligands are also indispensable, such as bipyridine The ligand complexes with the metal to stabilize the active center and adjust the selectivity of the reaction. The 1H-indazole reacts with iodine sources, such as iodine elemental or iodine aromatic hydrocarbons, in an alkaline environment. The base can capture the hydrogen of the substrate and increase its nucleophilicity. Common bases include potassium carbonate, sodium carbonate, etc. The reaction is carried out in an organic solvent, such as toluene, dioxane, with temperature control in an appropriate range, or heated to reflux. Through metal catalysis, iodine atoms can be efficiently and selectively connected to the third position of 1H-indazole to obtain 3-iodo-1H-indazole.
These two methods have their own advantages and disadvantages. The halogenation reaction step is simple and the conditions are easy to control; the transition metal catalysis method has excellent selectivity and higher yield. The experimenter should synthesize 3-iodo-1H-indazole according to the need.

What fields is 3-iodo-1h-indazole used in?

3-Iodo-1H-indazole is an organic compound that has applications in many fields.
In the field of medicinal chemistry, it has a wide range of applications. Because its structure contains specific atoms and functional groups, it is endowed with unique chemical properties and can be used as a key intermediate in drug development. For example, some studies aim to develop compounds with specific biological activities by modifying the structure of 3-iodo-1H-indazole, or for the creation of anticancer drugs. Because its structure can interact with specific targets of cancer cells, after chemical modification, it may precisely inhibit the growth and spread of cancer cells, providing new avenues for cancer treatment.
In the field of materials science, 3-iodo-1H-indazole also has potential applications. Its unique electronic properties and structural characteristics may be used to prepare new organic materials. For example, in the preparation of organic optoelectronic materials, it can be introduced into the material system to regulate the optical and electrical properties of materials, improve the photoelectric conversion efficiency of materials, and be used in the fabrication of solar cells, Light Emitting Diode and other devices to promote the development of materials science.
In the field of chemical synthesis, it is an important synthetic block. Chemists can use its iodine atom and indolazole ring to carry out various chemical reactions. Through nucleophilic substitution, coupling reactions, etc., more complex organic molecular structures are constructed, the chemical boundaries of organic synthesis are expanded, and organic compounds with special functions and structures are synthesized, providing a rich material basis for chemical research and industrial production.

What is the market outlook for 3-iodo-1h-indazole?

3-Iodo-1H-indazole is one of the organic compounds. Its market prospect is quite promising. This compound has a wide range of uses in the field of medicinal chemistry. In the process of drug development, it can be a key intermediate to help scientists create novel drugs, which may be beneficial for the treatment of various diseases, such as cancer, neurological diseases, etc. Because it can accurately participate in specific chemical reactions and construct biologically active molecular structures, it is favored by pharmaceutical developers.
It has also made its mark in the field of materials science. It can be used to prepare materials with special properties, such as optoelectronic materials. Due to its unique chemical structure, it may endow materials with excellent optical and electrical properties, and has potential application value in the manufacture of optoelectronic devices, such as Light Emitting Diodes, solar cells, etc.
From the perspective of market demand, with the development of medicine and materials science, the demand for 3-iodo-1H-indazole is expected to increase. Pharmaceutical companies may increase their demand for new therapies; researchers in the field of materials also hope to use its unique properties to develop high-performance materials. Although the current production scale may be limited, with the deepening of research and technological innovation, the production process is expected to be optimized, the cost will be reduced, and the output will be increased to meet the needs of market growth. Overall, the 3-iodo-1h-indazole market has a bright future and great potential for development in many fields.