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3-iodo-5-indazolecarboxylic chemical properties of Acid Methyl Ester
3-Iodine-5-indazolecarboxylic acid methyl ester, this is an organic compound. Its shape is mostly solid, but its specific physical properties also depend on the purity and preparation conditions.
In terms of chemical properties, this compound contains an ester group and an iodine atom, so it has corresponding chemical reactivity. The ester group can be hydrolyzed. Under acidic or basic conditions, it can react with water to generate 3-iodine-5-indazolecarboxylic acid and methanol, respectively. In alkaline hydrolysis, the reaction is usually rapid and thorough, and the resulting carboxylate has good solubility in water.
The iodine atom gives the compound the properties of halogenated hydrocarbons, which can participate in nucleophilic substitution reactions. For example, in the presence of appropriate nucleophiles, iodine atoms can be replaced by other groups to achieve molecular structure modification and modification, which is extremely important in organic synthesis. At the same time, the presence of the indazole ring also gives the compound a unique electronic effect and spatial structure, which affects its reactivity and selectivity.
Furthermore, due to the presence of multiple polar groups, the compound should have a certain solubility in common organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide, which facilitates its operation and separation in organic synthesis reactions. However, its solubility in water is limited due to the relatively large hydrophobic part of the molecule.
3-iodo-5-indazolecarboxylic Acid Methyl Ester
The synthesis method of Fu 3 - iodo - 5 - indazolecarboxylic Acid Methyl Ester has various ways. The common ones can be initiated by a substrate containing indole structure. First, the indole is halogenated under suitable conditions with a specific halogenated reagent, such as an iodine substitution reagent, and iodine atoms are introduced at specific positions. This step requires attention to the control of reaction conditions, such as temperature and solvent selection, so that the iodine atoms are accurately connected to the target check point.
Then, the resulting halogenated indole derivative is carboxylated with a suitable carboxylating reagent and carboxylated to introduce carboxyl groups. In this process, the choice of catalyst is very critical, which can promote the reaction and improve the reaction efficiency and selectivity.
After the carboxyl group is successfully introduced, the esterification reaction is carried out with an esterification reagent under mild conditions to convert the carboxyl group into a methyl ester group, resulting in 3-iodo-5-indazolecarboxylic Acid Methyl Ester. During operation, it is necessary to pay attention to the monitoring of the reaction process. You can use thin-layer chromatography and other means to detect the degree of the reaction and stop the reaction in time to avoid the growth of side reactions.
There are other methods, or the indolazole skeleton can be constructed from a specific substituted aromatic hydrocarbon through a multi-step cyclization reaction. During the cyclization process, iodine atoms and carboxyl methyl ester structures are introduced synchronously or step by step. This path requires in-depth exploration of the mechanism of the cyclization reaction, precise regulation of the reaction conditions, so that each step of the reaction occurs smoothly in sequence, and the synthesis of the target product can be achieved. In short, to synthesize this compound, it is necessary to study the conditions of each step of the reaction, the characteristics of the reagents, and carefully plan the synthesis route to obtain satisfactory results.
3-iodo-5-indazolecarboxylic Acid Methyl Ester is used in
3-Iodine-5-indazole carboxylic acid methyl ester is useful in various fields. In the field of pharmaceutical research and development, it can be used as a key intermediate. The structure of Gainindazole often has unique biological activities in many drug molecules, and this compound contains iodine and ester groups, which can be modified by chemical means to create new drugs, or to develop specific therapeutic agents for specific diseases.
In the field of organic synthesis, its position is also quite important. It can be the cornerstone of the construction of complex organic molecules, and it can be connected with other organic fragments through various organic reactions, such as coupling reactions, to expand the molecular structure to obtain organic compounds with specific functions and structures, and to provide novel compound raw materials for related fields such as materials science.
In the field of materials science, it may be appropriately modified to prepare materials with special properties. For example, the introduction of specific groups to make them exhibit unique photoelectric properties can be used in the manufacture of optoelectronic devices, such as organic Light Emitting Diodes, solar cells and other components, to open up new directions for material research and development.
And in scientific research and exploration, it can help chemists to deeply explore the mechanism of organic reactions. By studying the various reactions in which it participates, the key information such as reaction conditions and product selectivity can be clarified, so as to improve the theory of organic chemistry and lay a solid theoretical foundation for the innovation of subsequent organic synthesis methods. In short, methyl 3-iodine-5-indazole carboxylate has broad application potential and research value in many aspects such as medicine, organic synthesis, materials science and scientific research.
3-iodo-5-indazolecarboxylic the market price of Acid Methyl Ester
What you are asking is the market price of methyl 3-iodine-5-indazole carboxylate. However, the market price of this compound is difficult to say in a single word.
Covers the fluctuation of its price, which is affected by many factors. First and foremost, the cost of raw materials. If the various raw materials required for the synthesis of this compound are scarce, or the process of obtaining them is cumbersome and expensive, the price of this product will rise.
Furthermore, the synthesis process is also critical. If the process of synthesizing methyl 3-iodine-5-indazolecarboxylate is complicated, special equipment, harsh reaction conditions, or multi-step reaction and low yield are required, the production cost will increase significantly, which will affect the market price.
The supply and demand relationship in the market should not be underestimated. If the market demand for this compound is strong and the supply is relatively insufficient, merchants may raise prices; conversely, if the market demand is weak and the supply is excessive, the price may decline.
In addition, different manufacturers will also make prices different. Most well-known manufacturers pay attention to quality and reputation, and their product prices may be slightly higher; while some small factories, although the price may have advantages, the quality may be difficult to compete with large factories.
Therefore, in order to know the exact market price of methyl 3-iodine-5-indazole carboxylate, it is necessary to check the chemical product trading platform and consult the relevant chemical raw material suppliers to obtain more accurate price information.
What are the storage conditions for 3-iodo-5-indazolecarboxylic Acid Methyl Ester?
3-Iodine-5-indazolecarboxylate methyl ester, this is an organic compound. Its storage conditions are crucial, which is related to the quality and stability of this compound.
should be placed in a cool, dry and well-ventilated place. In a cool place, due to high temperature or increased molecular activity of the compound, chemical reactions and deterioration are triggered. Therefore, it is necessary to avoid direct sunlight and high temperature environments to prevent decomposition or other adverse chemical changes due to heat.
A dry environment is also indispensable. Water vapor in the air may interact with the compound or cause reactions such as hydrolysis, which damages its chemical structure. Therefore, the appropriate humidity for storage can be maintained by means of desiccants, etc., to maintain a dry environment.
Furthermore, good ventilation is essential. If the storage space is not well ventilated, the volatile gas of the compound may accumulate to a certain concentration, which not only affects the stability of the compound itself, but also poses a safety hazard, such as an open flame or explosion.
When storing, it also needs to be separated from oxidants, acids, alkalis and other substances. Due to its active chemical properties, contact with the above substances may cause severe chemical reactions, causing the compound to fail or even cause danger.
In addition, the container containing 3-iodine-5-indazole carboxylic acid methyl ester should be made of suitable materials. Usually glass or specific plastic containers are more suitable, and it is necessary to ensure that the container is well sealed to prevent air and water vapor from invading.
Only by following the above storage conditions can the quality of 3-iodine-5-indazole carboxylate be effectively guaranteed, so that it can play its due role in subsequent use.