3 Iodo 6 Nitroindazole

3-Iodo-6-nitroindazole is an organic compound. Looking at its name, it can be seen that this compound has indazole (indazole) as its parent nucleus. Indazole, a nitrogen-containing heterocyclic compound, is formed by fusing a benzene ring with a pyrazole ring.
In this compound, "3-iodo" indicates that there is an iodine atom attached at the No. 3 position of the indazole ring. The iodine atom has a large radius and has a certain electronegativity. Its introduction will affect the electron cloud distribution, spatial structure and chemical properties of the molecule.
"6-nitro" is shown to have a nitro (-NO 2) at the No. 6 position of the indazole ring. Nitro is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring, enhance the polarity of the molecule, and significantly affect the reactivity of the compound.
The chemical structure characteristics of this compound determine its unique physical and chemical properties. In the field of organic synthesis, due to the existence of iodine atoms, it may participate in nucleophilic substitution and other reactions as key intermediates; while the strong electron-absorbing properties of nitro groups, or affect the reactivity of other positions on the indazole ring, provide various possibilities for the construction of complex organic molecules.

3-Iodo-6-nitroindazole is an organic compound with a wide range of uses. In the field of pharmaceutical research and development, this compound can be used as a key intermediate to create drugs with specific biological activities. Due to its unique structure, it may interact with specific targets in organisms, thus demonstrating many potential effects such as antibacterial, antiviral, and antitumor. For example, in the exploration of anti-tumor drugs, scientists hope to find new drugs with highly selective killing effects on tumor cells by modifying and modifying their structures.
In the field of materials science, 3-iodo-6-nitroindazole also has potential applications. Due to the iodine and nitro groups it contains, it may endow materials with special optical and electrical properties. It can be introduced into polymer materials to prepare functional materials with special photoelectric response, which can be used in the manufacture of organic Light Emitting Diodes, sensors and other devices to improve the performance and function of such devices.
In addition, in the field of organic synthetic chemistry, this compound is an important synthetic building block and can participate in the construction of many complex organic molecules. Chemists can use various organic reactions to derive them according to their structural characteristics, synthesize organic compounds with more diverse and complex structures, expand the variety and quantity of organic compounds, and inject new vitality into the development of organic synthetic chemistry.

3-Iodo-6-nitroindazole is an important compound in organic synthesis. Its synthesis method can be described according to ancient chemistry.
Starting material, often indazole-based. First take an appropriate amount of indazole, place it in a reactor, dissolve it in an appropriate solvent, such as organic solvent dichloromethane, etc., to disperse it uniformly.
Then, nitro is introduced. Usually a mixed acid of nitric acid and sulfuric acid is used as a nitrifying agent. The mixed acid is slowly dropped into the solution containing indazole and reacted at low temperature and stirred. This is because the nitrification reaction is relatively violent, low temperature and stirring can make the reaction proceed smoothly, and the substitution position of nitro groups can be controlled. Nitro is preferentially substituted at a specific position on the indazole ring to form 6-nitroindazole.
After 6-nitroindazole is formed, the iodine substitution reaction is carried out. Often the iodine element (I ³) cooperates with an appropriate oxidant, such as hydrogen peroxide (H2O) or potassium persulfate (K2O S2O O). The iodine element and the oxidant are added to the system containing 6-nitroindazole. Under the appropriate temperature and reaction time, the iodine atom is replaced in a specific position to obtain 3-iodo-6-nitroindazole.
The entire synthesis process requires precise control of the reaction conditions, such as temperature, reagent dosage, reaction time, etc. If the temperature is too high, side reactions may occur; improper reagent dosage also affects the purity and yield of the product. And after each step of the reaction, it needs to be separated and purified, such as column chromatography, recrystallization method, etc., to obtain pure 3-iodo-6-nitroindazole. In this way, according to this synthesis method, the desired compound can be obtained.

3-Iodo-6-nitroindazole is an organic compound with unique physical and chemical properties. Its properties are mostly crystalline, and its color may be light yellow to light brown. Due to the existence of iodine and nitro groups in the molecular structure, the light absorption is different.
When it comes to the melting point, it is about a specific temperature range. Because the exact value is affected by impurities and measurement methods, it is difficult to determine the exact value. However, it is roughly within a certain range, which is related to the intermolecular force. Iodine and nitro enhance the intermolecular attraction, resulting in the need for higher energy to disintegrate the lattice, that is, the melting point increases.
In terms of solubility, it shows certain solubility in organic solvents such as dichloromethane and N, N-dimethylformamide. Because these solvents and 3-iodo-6-nitroindazole can form intermolecular forces, such as van der Waals forces, hydrogen bonds, etc., to help them disperse and dissolve. In water, the solubility is not good, because the molecular polarity is not well matched with water, it is difficult for water molecules to overcome their intermolecular forces and disperse them.
In terms of stability, it is sensitive to heat and light. When heated, the vibration of chemical bonds within the molecule intensifies, reaching a certain energy, and the bond breaks and causes decomposition. Under light, the molecule absorbs photon energy, and the electrons jump to the excited state, triggering chemical reactions such as isomerization or decomposition. Its chemical properties are active, iodine atom has nucleophilic substitution activity, nitro changes the electron cloud density of benzene ring, making it easy to react with nucleophilic reagents, and it can be used as a key intermediate in the field of organic synthesis.

I look at your question and ask about the price range of 3-iodo-6-nitroindazole in the market. However, this is not an easy question to answer. The price of building a market often changes due to many reasons.
First, the purity or impurity of the material has a huge impact on the price. If the 3-iodo-6-nitroindazole is pure, the price will be high; if it is mixed with other things, the quality will be low.
Second, the state of supply and demand is also the key. If there are many people in the market, and there are few people in supply, the price will rise; conversely, if the supply exceeds the demand, the price will fall.
Third, the cost of making this product also affects its price. For example, the price of the raw materials used, the simplicity of the method of making the product, and the consumption of manpower and material resources are all related to the cost, which in turn affects the price.
Fourth, the price varies depending on the seller. Large merchants may have relatively low prices due to the benefit of scale; small merchants may have slightly higher prices due to cost.
And I don't know what this 3-iodo-6-nitroindazole is used for. If it is used for scientific research, its quality needs to be refined, and the price may be expensive; if it is used for ordinary industrial use, the quality requirements are slightly lower, and the price may also drop.
However, it is difficult for me to determine the price range. If you want to know, you can visit the market of chemical materials, consult various merchants, or check the relevant transaction records and information platforms to get a more accurate price.