3-Iodo-Dl-Tyrosine

3-Iodo-dl-tyrosine, also known as 3-iodine-racemic tyrosine. Its transformation can be described as follows:
The core of this compound is tyrosine. Tyrosine, one of the α-amino acids. Its basic framework contains an α-carbon atom, which is divided into an amino group (-NH ²), a carboxyl group (-COOH), and an iodine group.
In 3-iodo-dl-tyrosine, the tyrosine benzene The third carbon atom is connected with an iodine atom (I). The "dl -" indicates that this compound is racemic, meaning that it contains left-handed (l -) and right-handed (d -), which are mixed in equal amounts and have no optical rotation.
Its formula can be approximated as follows: on a skeleton with the following arrangement, H ² N - CH (R) - COOH, where R represents phenylpropyl, and phenylpropyl has an iodine atom at the benzene 3 position. The special characteristics of this compound make it play a specific role in the production of multiple physiological processes and substances due to the introduction of iodine atoms or the different properties and activities of ordinary tyrosine.

3-Iodo-dl-tyrosine, Chinese name 3-iodo-dl-tyrosine, is an organic compound with wide uses in medicine, biochemical research and other fields.
First, in the field of medicine, this compound plays a pivotal role in thyroid hormone synthesis. The thyroid gland uses iodine to synthesize thyroid hormones, and 3-iodo-dl-tyrosine is a key intermediate product. Therefore, it is of great significance in thyroid disease research and therapeutic drug development. For example, the pathogenesis of some thyroid dysfunction diseases may be related to abnormal synthesis and metabolism of 3-iodo-dl-tyrosine. By studying its transformation process in vivo, it can provide a basis for disease diagnosis and treatment plan formulation.
Second, in biochemical research, it is an important tool. Scientists use it to explore the process and mechanism of protein iodization. Protein iodization regulates many biological processes, such as cell signaling, immune response, etc. Taking immune response as an example, iodization of some immune proteins may affect their activity and function. Using 3-iodo-dl-tyrosine can simulate the iodization environment in vivo, helping researchers to understand the details of protein iodization and reveal the mysteries of related biological processes.
Third, in pharmaceutical chemistry, 3-iodo-dl-tyrosine can be used as an intermediate in drug synthesis. Because its structure contains iodine atoms and tyrosine structural units, it has unique chemical properties and biological activities. Medicinal chemists can develop new drugs with specific pharmacological activities based on this structural modification and modification. For example, small molecule drugs that can precisely act on specific targets can be designed to provide more options for disease treatment.

3-Iodo-dl-tyrosine, that is, 3-iodo-racemic tyrosine, this material property is very different. Looking at its properties, it is a white to off-white powder under normal conditions, which is relatively stable in air, but is easy to gradually change when exposed to light. Its melting point is quite considerable, about 200 ° C. Under this high temperature, the molecular structure begins to change.
In terms of solubility, 3-iodo-racemic tyrosine dissolves very little in water, just like sand and stones entering water, and it is difficult to form a uniform state. However, in dilute alkali solutions, it can be better dissolved, such as salt into soup, gradually melting invisible. In organic solvents, such as ethanol and ether, its solubility is also low, just like oil and water, and it is distinct.
This compound has amphoteric properties, because its structure contains amino and carboxyl groups. When exposed to acid, the amino group can bind to protons, showing alkaline performance; when it is alkali, the carboxyl group can give protons, showing acidic characteristics.
3-Iodine-racemic tyrosine is radioactive because it contains iodine atoms. Although it is weak, it still needs to be protected during use and storage to prevent radiation damage. Its chemical activity is unique, and iodine atoms can participate in a variety of chemical reactions, forming new chemical bonds and deriving other compounds. And because its structure is similar to tyrosine, it may participate in specific biochemical processes in living organisms and affect physiological functions.

3-Iodo-dl-tyrosine is also known as 3-iodo-racemic tyrosine. Its synthesis method has also been explored in the past.
One method can start from tyrosine and introduce iodine atoms by halogenation reaction. First, the tyrosine is placed in an appropriate reaction system, often dissolved in a suitable solvent, such as alcohol or a mixed system of water and organic solvents. Then, an iodine source, such as iodine elemental substance (I2O), is added, and an appropriate catalyst, such as potassium iodide (KI), is added. This catalyst can promote the reactivity of iodine and accelerate the replacement of hydrogen atoms on the tyrosine phenyl ring by iodine atoms. Under the control of suitable temperature and reaction time, the reaction can proceed smoothly. If the temperature is too high, side reactions may occur. If it is too low, the reaction rate will be delayed. Generally speaking, the reaction temperature may be controlled in the range of tens of degrees Celsius. After several hours of reaction, the 3-iodo-dl-tyrosine product can be obtained. After separation and purification, such as recrystallization, column chromatography, etc., to obtain a pure product.
There is another way to use the protected tyrosine derivative as the starting material. First protect the active groups of tyrosine, such as amino groups and carboxyl groups, to avoid unnecessary reactions during halogenation. The protected derivatives react with the iodine source under specific reaction conditions. After the iodine atom is successfully introduced, the protective group is removed. Although this step is slightly complicated, it can improve the selectivity of the reaction and the purity of the product. The selection of protective groups is crucial, considering that they are easy to introduce and remove, and can exist stably during the halogenation reaction. After a series of reaction operations and separation and purification methods, 3-iodo-dl-tyrosine can be obtained. These synthesis methods require fine operation and precise control of the reaction conditions to achieve satisfactory results.

Prices in Wuguan shops often change from time to time, and also vary according to the location and quality of the product. However, it is not easy to determine the market price range of 3-iodo-dl-tyrosine. Covering this product or using it in various fields, such as pharmaceutical research and development, biochemical research, etc., the trend of demand and supply changes at any time, resulting in uncertain price fluctuations.
I have heard that in the past market transactions, the prices of similar products are also very different due to differences in quality. 3-iodo-dl-tyrosine If it is used in medicine, it is related to human life and health, its quality must be excellent, and the price is high; if it is used in ordinary biochemical research, the quality is slightly inferior, and the price may be slightly reduced.
And looking at the production of the four sides, where the production is abundant, the price may be easy; if the origin is scarce and trafficked far away, the price will increase again, adding to the freight and preservation costs. However, in my humble opinion, the current business situation is complicated. Although I want to seek wide acquisition, it is difficult to be sure. Or in special pharmaceutical markets and biochemical stores, ask merchants, or you can get their approximate prices. The price may vary depending on the quantity, and buying in bulk may have a profit; taking a little from zero will be expensive. However, if you want to get an accurate price range, you still need to go to the city in person and visit many places to get it.